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DABA aminotransferase/decarboxylase
L-2,4-diaminobutyrate aminotransferase/decarboxylase
L-2,4-diaminobutyrate decarboxylase
L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase
-
L-2,4-diaminobutyric acid decarboxylase
additional information
the enzyme belongs to the subgroup II of the aminotransferases
DABA aminotransferase/decarboxylase
-
-
DABA aminotransferase/decarboxylase
Vibrio cholerae serotype O1 El Tor
-
-
-
DABA AT/DC
-
-
DABA AT/DC
Vibrio cholerae serotype O1 El Tor
-
-
-
DABA DC
-
-
DABA decarboxylase
-
-
DABA decarboxylase
Vibrio cholerae serotype O1 NCTC4716
-
-
-
DABA-DC
-
-
L-2,4-diaminobutyrate aminotransferase/decarboxylase
-
-
L-2,4-diaminobutyrate aminotransferase/decarboxylase
Vibrio cholerae serotype O1 El Tor
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
L-2,4-diaminobutyrate decarboxylase
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
-
L-2,4-diaminobutyrate decarboxylase
-
-
L-2,4-diaminobutyrate decarboxylase
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
Vibrio cholerae serotype O1 NCTC4716
-
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
L-2,4-diaminobutyric acid decarboxylase
-
-
-
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4-aminobutanoate
propylamine + CO2
-
-
-
?
DL-2,4-diaminobutanoate
propane-1,3-diamine + CO2
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
L-2,4-diaminobutanoate + 2-oxoglutarate
L-aspartic beta-semialdehyde + L-glutamic acid
the enzyme is highly specific for 2-oxoglutarate
-
-
r
L-2,4-diaminobutyrate
? + CO2
L-lysine
1,5-diaminopentane + CO2
L-ornithine
1,4-diaminobutane + CO2
additional information
?
-
DL-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
DL-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
GC-MS product identification
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
specific for
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
specific for
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
the enzyme is involved in polyamine biosynthesis
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
the enzyme is involved in polyamine biosynthesis
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
propane-1,3-diamine is a precursor for norspermidine, the enzyme is involved in biosynthesis of norspermidine
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
stereospecific reaction, no activity with the D-isomer
product identification
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
stereospecific reaction, no activity with the D-isomer
product identification
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
Vibrio cholerae serotype O1 NCTC4716
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutyrate
? + CO2
-
DABA AT/DC fusion protein exhibits a preference for L-2,4-diaminobutyrate over L-ornithine by 1000fold
-
-
?
L-2,4-diaminobutyrate
? + CO2
Vibrio cholerae serotype O1 El Tor
-
DABA AT/DC fusion protein exhibits a preference for L-2,4-diaminobutyrate over L-ornithine by 1000fold
-
-
?
L-lysine
1,5-diaminopentane + CO2
-
-
-
?
L-lysine
1,5-diaminopentane + CO2
the catalytic efficiency of the enzyme is 24fold higher with L-2,4-diaminobutanoate than with L-lysine
-
-
?
L-ornithine
1,4-diaminobutane + CO2
low activity
-
-
?
L-ornithine
1,4-diaminobutane + CO2
-
Kcat/Km is 1000fold lower than with L-2,4-diaminobutyrate
-
-
?
L-ornithine
1,4-diaminobutane + CO2
Vibrio cholerae serotype O1 El Tor
-
Kcat/Km is 1000fold lower than with L-2,4-diaminobutyrate
-
-
?
additional information
?
-
substrate specificity of the purified recombinant enzyme, L-2,3-diaminopropionic acid is a poor substrate
-
-
?
additional information
?
-
-
substrate specificity of the purified recombinant enzyme, L-2,3-diaminopropionic acid is a poor substrate
-
-
?
additional information
?
-
-
no activity with 4-N-acetyl-L-2,4-diaminobutanoate, L-2,3-diaminopropionate, L-ornithine, and L-lysine
-
-
?
additional information
?
-
-
no activity with 4-N-acetyl-L-2,4-diaminobutanoate, L-2,3-diaminopropionate, L-ornithine, and L-lysine
-
-
?
additional information
?
-
-
no activity with 2,3-diaminopropionate, ornithine, lysine, or arginine
-
-
?
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L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
the enzyme is involved in polyamine biosynthesis
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
the enzyme is involved in polyamine biosynthesis
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
propane-1,3-diamine is a precursor for norspermidine, the enzyme is involved in biosynthesis of norspermidine
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
Vibrio cholerae serotype O1 NCTC4716
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
L-2,4-diaminobutanoate
propane-1,3-diamine + CO2
-
-
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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3660fold to homogeneity by ammonium sulfate fractionation, gel filtration, and two steps of ion exchange chromatography
-
DABA AT/DC affinity-purified
-
HiTrap chelating column chromatography, and gel filtration
native enzyme 168fold by ammonium sulfate fractionation, ion exchange chromatography, and gel filtration
-
native enzyme 1750fold to homogeneity by two steps of ion exchange chromatography, gel filtration, hydroxyapatite chromatography, and another two steps of ion exchange chromatography
-
native enzyme 2150fold to homogeneity by ammonium sulfate fractionation, two steps of ion exchange chromatography, and two steps of gel filtration
-
native enzyme 22.7fold by ammonium sulfate fractionation and anion exchange chromatography
-
native enzyme 886fold to homogeneity by two steps of ion exchange chromatography, gel filtration, hydroxyapatite chromatography, and another two steps of ion exchange chromatography
-
recombinant enzyme from Escherichia coli strain HB101
recombinant enzyme from Escherichia coli strain HB101 to homogeneity by ammonium sulfate fractionation, ion exchange chromatography, gel filtration, and hydroxylapatite chromatography
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Ikai, H.; Yamamoto, S.
Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii
J. Bacteriol.
179
5118-5125
1997
Acinetobacter baumannii (P56744), Acinetobacter baumannii
brenda
Ikai, H.; Yamamoto, S.
Sequence analysis of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii: similarity to the group II amino acid decarboxylases
Arch. Microbiol.
166
128-131
1996
Acinetobacter baumannii (Q43908), Acinetobacter baumannii
brenda
Yamamoto, S.; Ikai, H.; Uesugi, T.; Horie, A.; Hirai, Y.
Occurrence and antigenic heterogeneity of L-2,4-diaminobutyrate decarboxylase in Acinetobacter species
Biol. Pharm. Bull.
18
454-456
1995
Acinetobacter baumannii, Acinetobacter calcoaceticus, Acinetobacter baumannii ATCC 19606
brenda
Yamamoto, S.; Mutoh, N.; Ikai, H.; Nagasaka, M.
Occurrence of a novel L-2,4-diaminobutyrate decarboxylase activity in some species of Enterobacteriaceae, and purification and characterization of the enzymes of Enterobacter aerogenes and Serratia marcescens
Biol. Pharm. Bull.
19
1298-1303
1996
Klebsiella aerogenes, Enterobacter cloacae, Citrobacter freundii, Pantoea agglomerans, Klebsiella oxytoca, Klebsiella pneumoniae, Serratia liquefaciens, Serratia marcescens, Serratia liquefaciens RM 2-Ia
brenda
Yamamoto, S.; Mutoh, N.; Tsuzuki, D.; Ikai, H.; Nakao, H.; Shinoda, S.; Narimatsu, S.; Miyoshi, S.I.
Cloning and characterization of the ddc homolog encoding L-2,4-diaminobutyrate decarboxylase in Enterobacter aerogenes
Biol. Pharm. Bull.
23
649-653
2000
Klebsiella aerogenes (Q9S0P8), Klebsiella aerogenes
brenda
Yamamoto, S.; Tsuzaki, Y.; Kishi, R.; Nakao, H.
Occurrence of L-2,4-diaminobutyrate decarboxylase activity in Acinetobacter
Chem. Pharm. Bull.
39
2451-2453
1991
Acinetobacter calcoaceticus
brenda
Ikai, H.; Yamamoto, S.
Cloning and expression in Escherichia coli of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii
FEMS Microbiol. Lett.
124
225-228
1994
Acinetobacter baumannii, Acinetobacter baumannii ATCC 19606
brenda
Yamamoto, S.; Suemoto, Y.; Seito, Y.; Nakao, H.; Shinoda, S.
The presence of L-2,4-diaminobutyric acid decarboxylase activity in Vibrio species: a new biosynthetic pathway for 1,3-diaminopropane
FEMS Microbiol. Lett.
35
289-293
1986
Vibrio proteolyticus, Vibrio alginolyticus, Vibrio anguillarum, Salinivibrio costicola, Vibrio cholerae serotype O1, Vibrio alginolyticus ATCC 17749, Vibrio anguillarum NCMB6, Vibrio proteolyticus ATCC 15338, Vibrio cholerae serotype O1 NCTC4716, Salinivibrio costicola NCMB701
-
brenda
Nakao, H.; Takeuchi, K.; Shinoda, S.; Yamamoto, S.
L-2,4,-Diaminobutyric acid decarboxylase activity responsible for the formation of 1,3-diaminopropane in Enterobacter aerogenes
FEMS Microbiol. Lett.
70
61-66
1990
Klebsiella aerogenes, Klebsiella aerogenes NCTC 10006
-
brenda
Nakao, H.; Ishii, M.; Shinoda, S.; Yamamoto, S.
Purification and some properties of a novel L-2,4-diaminobutyric acid decarboxylase from Vibrio alginolyticus
J. Gen. Microbiol.
135
345-351
1989
Vibrio alginolyticus
brenda
Yamamoto, S.; Tsuzaki, Y.; Tougou, K.; Shinoda, S.
Purification and characterization of L-2,4-diaminobutyrate decarboxylase from Acinetobacter calcoaceticus
J. Gen. Microbiol.
138
1461-1465
1992
Acinetobacter calcoaceticus, Acinetobacter calcoaceticus ATCC 23055
brenda
Lee, J.; Sperandio, V.; Frantz, D.E.; Longgood, J.; Camilli, A.; Phillips, M.A.; Michael, A.J.
An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae
J. Biol. Chem.
284
9899-9907
2009
Vibrio cholerae serotype O1, Vibrio cholerae serotype O1 El Tor
brenda
Burrell, M.; Hanfrey, C.C.; Kinch, L.N.; Elliott, K.A.; Michael, A.J.
Evolution of a novel lysine decarboxylase in siderophore biosynthesis
Mol. Microbiol.
86
485-499
2012
Trichormus variabilis (Q3M985), Trichormus variabilis
brenda