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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
cdp-diglyceride hydrolase, cdpdiacylglycerol pyrophosphatase,
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CDP diacylglycerol hydrolase
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CDP-diacylglycerol phosphatidylhydrolase
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CDP-diglyceride hydrolase
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CDPdiacylglycerol pyrophosphatase
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cytidine diphosphodiacylglycerol pyrophosphatase
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CDP-diacylglycerol + H2O = CMP + phosphatidate
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phosphorous acid anhydride hydrolysis
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CDP-diacylglycerol phosphatidylhydrolase
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CDP-1-stearoyl-2-oleoylglycerol + H2O
CMP + 1-stearoyl-2-oleoyl-sn-glycerol-3-phosphate
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CDP-1-stearoyl-2-stearoylglycerol + H2O
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
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CDPdiacylglycerol + H2O
CMP + phosphatidate
CDPdipalmitoylglycerol + H2O
CMP + 1,2-dipalmitoyl-sn-glycerol-3-phosphate
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CDPdistearoylglycerol + H2O
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
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CDPdiacylglycerol + H2O
CMP + phosphatidate
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CDPdiacylglycerol + H2O
CMP + phosphatidate
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CDPdiacylglycerol + H2O
CMP + phosphatidate
CDPdiacylglycerol + H2O
CMP + phosphatidate
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CDPdiacylglycerol + H2O
CMP + phosphatidate
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additional information
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no requirement for added metal ions
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AMP
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none competitive, Ki: 0.04 mM
AMP
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very strong inhibition
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Triton X-100
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detergent required for activity, optimum concentration 0.3%
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0.04
CDP-1-stearoyl-2-oleoylglycerol
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0.047
CDP-1-stearoyl-2-stearoylglycerol
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0.063
CDPdipalmitoylglycerol
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0.14
CDPdistearoylglycerol
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brenda
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brenda
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brenda
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brenda
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brenda
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Raetz, C.R.H.; Hirschberg, C.B.; Dowhan, W.; Wickner, W.T.; Kenney, E.P.
A membrane-bound pyrophosphatase in Escherichia coli catalyzing the hydrolysis of cytidine diphosphate-diglyceride
J. Biol. Chem.
247
2245-2247
1972
Escherichia coli
brenda
Murthy, P.P.N.; Agranoff, B.W.
Stereospecific synthesis and enzyme studies of CDP-diacylglycerols
Biochim. Biophys. Acta
712
473-483
1982
Cavia porcellus
brenda
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