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4-amino-1-(beta-D-glucuronosyl)pyrimidin-2(1H)-one + H2O
1-(beta-D-glucuronosyl)-4-hydroxypyrimidin-2(1H)-one
acetylblasticidin S + H2O
acetyldeaminohydroxyblasticidin S + NH3
alanylcytosinine + H2O
?
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
blasticidin S methylester + H2O
deaminohydroxyblasticidin S methylester + NH3
-
only slightly deaminated
-
-
?
cytosinine + H2O
?
-
only slightly deaminated
-
-
?
demethylblasticidin S + H2O
?
-
-
-
-
?
dihydroblasticidin S + H2O
?
-
-
-
-
?
dihydrocytomycin + H2O
?
-
-
-
-
?
phenylalanylcytosinine + H2O
?
-
-
-
-
?
pyrimidinoblasticidin S + H2O
pyrimidinodeaminohydroxyblasticidin S + NH3
-
-
-
-
?
additional information
?
-
4-amino-1-(beta-D-glucuronosyl)pyrimidin-2(1H)-one + H2O
1-(beta-D-glucuronosyl)-4-hydroxypyrimidin-2(1H)-one
-
low activity
-
-
?
4-amino-1-(beta-D-glucuronosyl)pyrimidin-2(1H)-one + H2O
1-(beta-D-glucuronosyl)-4-hydroxypyrimidin-2(1H)-one
-
low activity
-
-
?
acetylblasticidin S + H2O
acetyldeaminohydroxyblasticidin S + NH3
-
-
-
-
?
acetylblasticidin S + H2O
acetyldeaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
blasticidin S + H2O
deaminohydroxyblasticidin S + NH3
-
-
-
-
?
cytidine + H2O
?
-
-
-
-
?
cytidine + H2O
?
-
only slightly deaminated
-
-
?
cytomycin + H2O
?
-
-
-
-
?
cytomycin + H2O
?
-
-
-
-
?
cytomycin + H2O
?
-
-
-
-
?
cytomycin + H2O
?
-
-
-
-
?
cytomycin + H2O
?
-
-
-
-
?
deoxycytidine + H2O
?
-
-
-
-
?
deoxycytidine + H2O
?
-
only slightly deaminated
-
-
?
gougerotin + H2O
?
-
only slightly deaminated
-
-
?
gougerotin + H2O
?
-
only slightly deaminated
-
-
?
mildiomycin + H2O
?
-
low activity
-
-
?
mildiomycin + H2O
?
-
low activity
-
-
?
additional information
?
-
-
cytosine, cytidine, deoxycytidine, CMP, d-CMP or purine nucleosides are no substrates
-
-
?
additional information
?
-
-
cytosine is no substrate
-
-
?
additional information
?
-
-
cytosine, cytosinine, CMP, d-CMP, adenine, adenosine, AMP, guanine, guanosine, GMP or other purine bases or their nucleosides are no substrates
-
-
?
additional information
?
-
-
cytosine, CMP, d-CMP, adenine, guanine and their nucleosides and nucleotides are no substrates
-
-
?
additional information
?
-
-
cytosine, cytosinine, CMP, d-CMP, adenine, adenosine, AMP, guanine, guanosine, GMP or other purine bases or their nucleosides are no substrates
-
-
?
additional information
?
-
-
cytidine and arabinosylcytosine are no substrates
-
-
?
additional information
?
-
-
cytidine and arabinosylcytosine are no substrates
-
-
?
additional information
?
-
-
cytidine and arabinosylcytosine are no substrates
-
-
?
additional information
?
-
-
the enzyme does not catalyze the deamination of CMP
-
-
?
additional information
?
-
-
the enzyme does not catalyze the deamination of CMP
-
-
?
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Airway Obstruction
Use of an electrothermal, feedback-controlled, bipolar sealing device for resection of the elongated portion of the soft palate in dogs with obstructive upper airway disease.
Apnea
Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function.
Apraxias
Deficient body structural description contributes to apraxic end-position errors in imitation.
Arthralgia
Comparison of the toxicity of two treatment schemes with benznidazole for chronic Chagas disease: a prospective cohort study in two Spanish referral centres.
Blindness
A model of the incidence and consequences of choroidal neovascularization secondary to age-related macular degeneration. Comparative effects of current treatment and potential prophylaxis on visual outcomes in high-risk patients.
Brain Death
Optimal management of brain-dead organ donor.
Breast Neoplasms
Facilitating informed decisions about breast cancer screening: development and evaluation of a web-based decision aid for women in their 40s.
Carcinoma
Multimodal ultrasonographic algorithm in the differentiation of submandibular masses.
Cerebrospinal Fluid Leak
Tension Pneumocephalus Following Balloon Sinuplasty.
Cholangitis
Biliary sphincterotomy dilation for the extraction of difficult common bile duct stones.
Chronobiology Disorders
Circadian Rhythm Dysregulation in Bipolar Spectrum Disorders.
Colitis
pH-Sensitive nanospheres for colon-specific drug delivery in experimentally-induced colitis rat model.
Confusion
Associations of Buying-Shopping Disorder Symptoms with Identity Confusion, Materialism, and Socially Undesirable Personality Features in a Community Sample.
Confusion
Object attachment in buying-shopping disorder.
Congenital Abnormalities
Is oxidative stress the mechanism of blue sac disease in retene-exposed trout larvae?
Deglutition Disorders
Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function.
Dementia
Apolipoprotein epsilon4 status is associated with behavioral symptoms in nursing home residents with dementia.
Dementia
Behavioral and psychological symptoms of dementia in developing countries.
Dementia
Consecutive brain SPECT surface three-dimensional displays show progression of cerebral cortical abnormalities in Alzheimer's disease
Dementia
The effect of therapeutic touch on behavioral symptoms and cortisol in persons with dementia.
Dementia
The nursing assistants' communication style and the behavioral symptoms of dementia in Korean-American nursing home residents.
Diabetes Mellitus, Type 1
Impact of the Balanced School Day on Glycemic Control in Children with Type 1 Diabetes.
Discitis
Comparison of brucellar and tuberculous spondylodiscitis patients: results of the multicenter "Backbone-1 Study".
Disorders of Excessive Somnolence
Development and validation of the Maugeri Sleep Quality and Distress Inventory (MaSQuDI-17).
Disorders of Excessive Somnolence
Sleep and daytime behavior in children with obstructive sleep apnea and behavioral sleep disorders.
Gastroesophageal Reflux
Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease.
Gastroesophageal Reflux
Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function.
Heart Failure
Triple Björk-Shiley valve--more than 30 years of asymptomatic functioning: to the memory of late academic prof. Isidor Papo and the 45th anniversary of the first valve implantation in Yugoslavia.
Hypersensitivity
Assessment and Treatment of Bipolar Spectrum Disorders in Emerging Adulthood: Applying the Behavioral Approach System Hypersensitivity Model.
Hypersensitivity
The Development and Course of Bipolar Spectrum Disorders: An Integrated Reward and Circadian Rhythm Dysregulation Model.
Infections
Identification of genetic markers linked to banana streak disease expression in inter-specific Musa hybrids.
Leukopenia
Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease.
Liver Failure
Slow Continuous Ultrafiltration with Bound Solute Dialysis.
Malaria
Rapid positive selection of stable integrants following transfection of Plasmodium falciparum.
Mania
Clinical consequences of under-recognized bipolar spectrum disorder.
Mania
Phenomenology of bipolar disorder not otherwise specified in youth: a comparison of clinical characteristics across the spectrum of manic symptoms.
Mania
Placebo-controlled study of quetiapine monotherapy in ambulatory bipolar spectrum disorder with moderate-to-severe hypomania or mild mania.
Mania
Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild mania.
Mania
The high prevalence of bipolar spectrum disorders in young adults with recurrent depression: toward an innovative diagnostic framework.
Mania
Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders.
Nasal Polyps
The intraoperative accuracy of maxillary balloon dilation: a blinded trial.
Nasopharyngeal Carcinoma
Reduction in stray radiation dose using a body-shielding device during external radiation therapy.
Neoplasms
Clinical implementation of target tracking by breathing synchronized delivery.
Neoplasms
Current indications for balloon sinuplasty.
Neoplasms
Deep local and regional hyperthermia with annular phased array.
Neoplasms
Reduction in stray radiation dose using a body-shielding device during external radiation therapy.
Neoplasms
Regional hyperthermia for deep-seated malignancies using the BSD annular array.
Neoplasms
Temperature data and specific absorption rates in pelvic tumours: predictive factors and correlations.
Neoplasms
The effect of hyperthermia and radiation on small bowel permeability using 51Cr EDTA and 14C mannitol in man.
Neoplasms
Thermoradiotherapy of pelvic tumours with the BSD 2000: first clinical results.
Obesity
Binge Eating Disorder and Bipolar Spectrum disorders in obesity: Psychopathological and eating behaviors differences according to comorbidities.
Obesity
Bipolar Spectrum Disorders in Male Youth: The Interplay between Symptom Severity, Inflammation, Steroid Secretion, and Body Composition.
Obesity
Bipolar spectrum features in obese individuals.
Osteonecrosis
Bone-Specific Drugs and Osteonecrosis of Sites Other Than the Jaw: A Nationwide Cohort Study.
Overweight
Bipolar Spectrum Disorders in Male Youth: The Interplay between Symptom Severity, Inflammation, Steroid Secretion, and Body Composition.
Overweight
Body shape dissatisfaction is a 'normative discontent' in a young-adult Nigerian population: A study of prevalence and effects on health-related quality of life.
Overweight
Prevalence and magnitude of body weight and shape dissatisfaction among university students.
Pancreatic Neoplasms
Locoregional peritoneal hyperthermia to enhance the effectiveness of chemotherapy in patients with peritoneal carcinomatosis: a simulation study comparing different locoregional heating systems.
Pancreatitis
Biliary sphincterotomy dilation for the extraction of difficult common bile duct stones.
Persistent Vegetative State
Knowledge, acceptance and perception towards brainstem death among medical students in Hong Kong: a questionnaire survey on brainstem death.
Pneumocephalus
Tension Pneumocephalus Following Balloon Sinuplasty.
Prostatic Neoplasms
Peripheral neuropathy and myonecrosis following hyperthermia and radiation therapy for recurrent prostatic cancer: correlation of damage with predicted SAR pattern.
Psoas Abscess
Comparison of brucellar and tuberculous spondylodiscitis patients: results of the multicenter "Backbone-1 Study".
Psychomotor Agitation
Apolipoprotein epsilon4 status is associated with behavioral symptoms in nursing home residents with dementia.
Sarcopenia
Association of the Baltic Sea and Mediterranean diets with indices of sarcopenia in elderly women, OSPTRE-FPS study.
Sepsis
Rates of Comorbidities in Very Low Birth Weight Infants Fed an Exclusive Human Milk Diet Versus a Bovine Supplemented Diet.
Sinusitis
Current indications for balloon sinuplasty.
Sinusitis
Medical therapy versus sinus surgery by using balloon sinus dilation technology: A prospective multicenter study.
Sinusitis
Office-based balloon sinus dilation: a prospective, multicenter study of 203 patients.
Sleep Apnea Syndromes
Sleep and daytime behavior in children with obstructive sleep apnea and behavioral sleep disorders.
Sleep Initiation and Maintenance Disorders
Development and validation of the Maugeri Sleep Quality and Distress Inventory (MaSQuDI-17).
Sleep Wake Disorders
Development and validation of the Maugeri Sleep Quality and Distress Inventory (MaSQuDI-17).
Sleep Wake Disorders
Sleep and daytime behavior in children with obstructive sleep apnea and behavioral sleep disorders.
Stomach Diseases
Gastric mucosal pathology in Belgian Shepherd dogs with and without clinical signs of gastric disease.
Stroke
Deficient body structural description contributes to apraxic end-position errors in imitation.
Stroke
Does Prestroke Depression Impact Poststroke Depression and Treatment?
Stroke
Hearts From DCD Donors Display Acceptable Biventricular Function After Heart Transplantation in Pigs.
Uterine Cervical Neoplasms
Radiochemotherapy combined with regional pelvic hyperthermia induces high response and resectability rates in patients with nonresectable cervical cancer > or =FIGO IIB "bulky".
Vitamin A Deficiency
Serum and hepatic vitamin A levels in captive and wild marine toads (Bufo marinus).
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Yamaguchi, I.; Shibata, H.; Seto, H.; Misato, T.
Isolation and purification of blasticidin S deaminase from Aspergillus terreus
J. Antibiot.
28
7-14
1975
Aspergillus flavipes, Aspergillus flavus, Aspergillus fumigatus, Aspergillus ochraceus, Aspergillus terreus, Aspergillus ustus, Aspergillus flavipes NHL 5013, Aspergillus ustus 1004, Aspergillus fumigatus NHL 5009, Aspergillus ochraceus 67-MI-87, Aspergillus terreus NHL 5037
brenda
Misato, T.; Yamaguchi, I.
Blasticidin S deaminase production by Aspergillus
Jpn. Kokai JP48099383 JP72-33359
19 pp
1973
Aspergillus terreus
-
brenda
Yamaguchi, I.; Misato, T.
Active center and mode of reaction of blasticidin S deaminase
Agric. Biol. Chem.
49
3355-3361
1985
Aspergillus terreus
-
brenda
Yamaguchi, I.; Sheto, H.; Misato, T.
Substrate binding by blasticidin S deaminase, an aminohydrolase for novel 4-aminopyrimidine nucleosides
Pestic. Biochem. Physiol.
25
54-62
1986
Aspergillus fumigatus, Aspergillus terreus, Bacillus sp. (in: Bacteria), Streptomyces sp.
-
brenda
Endo, T.; Furuta, K.; Kaneko, A.; Katsiki, T.; Kobayashi, K.
Inactivation of blasticidin S by Bacillus cereus. I. Inactivation mechanism
J. Antibiot.
40
1791-1793
1987
Bacillus cereus, Bacillus cereus K55-S2, Bacillus cereus K55-S1
brenda
Kamakura, T.; Kobayashi, I.; Tanaka, T.; Yamaguchi, I.; Endo, T.
Cloning and expression of a new structuralgene for blasticidin S deaminase, a nucleoside aminohydrolase
Agric. Biol. Chem.
51
3165-3168
1987
Bacillus cereus, Bacillus cereus K55-S1
-
brenda
Kimura, M.; Kamakura, T.; Tao, Q.Z.; Kaneko, I.; Yamaguchi, I.
Cloning of the blasticidin S deaminase from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae
Mol. Gen. Genet.
242
121-129
1994
Aspergillus terreus, Bacillus sp. (in: Bacteria)
brenda
Tamura, K.; Kimura, M.; Yamaguchi, I.
Blasticidin S deaminase gene(BSD): a new selection marker gene for tranformation of arabidopsis thaliana and Nicotiana tabacum
Biosci. Biotechnol. Biochem.
59
2336-2338
1995
Aspergillus terreus
brenda
Karremann, C.
New positive/negative selectable markers for mammalian cells on the basis of blasticidin deaminase-thymidine kinase fusions
Nucleic Acids Res.
26
2508-2510
1998
Aspergillus terreus
brenda
Nakasako, M.; Kimura, M.; Yamaguchi, I.
Crystallization and preliminary X-ray diffraction studies of blasticidin S deaminase from Aspergillus terreus
Acta Crystallogr. Sect. D
55
547-548
1999
Aspergillus terreus
brenda
Fukuda, H.; Kizaki, Y.
A new transformation system of Saccharomyces cerevisiae with blasticidin S deaminase gene
Biotechnol. Lett.
21
969-971
1999
Aspergillus terreus
-
brenda
Kimura, M.; Sekido, S.; Isogai, Y.; Yamaguchi, I.
Expression, purification, and characterization of blasticidin S deaminase (BSD) from Aspergillus terreus: The role of catalytic zinc in enzyme structure
J. Biochem.
127
955-963
2000
Aspergillus terreus, Bacillus cereus
brenda
Kimura, M.; Furuichi, M.; Yamamoto, M.; Kumasaka, T.; Mizuno, H.; Miyano, M.; Yamaguchi, I.
The flexible C-terminal region of Aspergillus terreus blasticidin S deaminase: identification of its functional roles with deletion enzymes
Biochem. Biophys. Res. Commun.
290
421-426
2002
Aspergillus terreus (P0C2P0), Aspergillus terreus
brenda
Kumasaka, T.; Yamamoto, M.; Furuichi, M.; Nakasako, M.; Teh, A.H.; Kimura, M.; Yamaguchi, I.; Ueki, T.
Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc
J. Biol. Chem.
282
37103-37111
2007
Aspergillus terreus (P0C2P0), Aspergillus terreus S-712 / ATCC 28865 (P0C2P0)
brenda
Bugorsky, R.; Perriard, J.C.; Vassalli, G.
Genetic selection system allowing monitoring of myofibrillogenesis in living cardiomyocytes derived from mouse embryonic stem cells
Eur. J. Histochem.
52
1-10
2008
Aspergillus terreus
brenda
Li, L.; Wu, J.; Deng, Z.; Zabriskie, T.M.; He, X.
Streptomyces lividans blasticidin S deaminase and its application in engineering a blasticidin S-producing strain for ease of genetic manipulation
Appl. Environ. Microbiol.
79
2349-2357
2013
Streptomyces lividans, Streptomyces lividans HXY16
brenda
Buck, J.M.; Rio Bartulos, C.; Gruber, A.; Kroth, P.G.
Blasticidin-S deaminase, a new selection marker for genetic transformation of the diatom Phaeodactylum tricornutum
PeerJ
6
e5884
2018
Phaeodactylum tricornutum
brenda