Information on EC 3.5.1.47 - N-acetyldiaminopimelate deacetylase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY hide
3.5.1.47
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RECOMMENDED NAME
GeneOntology No.
N-acetyldiaminopimelate deacetylase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N-acetyl-LL-2,6-diaminoheptanedioate + H2O = acetate + LL-2,6-diaminoheptanedioate
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
L-lysine biosynthesis II
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lysine metabolism
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Lysine biosynthesis
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Metabolic pathways
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Biosynthesis of secondary metabolites
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SYSTEMATIC NAME
IUBMB Comments
N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
99193-93-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene dapE
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
N-acetyl-LL-2,6-diaminoheptanedioate + H2O
acetate + LL-2,6-diaminoheptanedioate
show the reaction diagram
N-acetyl-LL-2,6-diaminopimelic acid + H2O
?
show the reaction diagram
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intermediate in the diaminopimelic acid pathway
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N-acetyl-LL-2,6-diaminopimelic acid + H2O
acetate + LL-2,6-diaminopimelic acid
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
N-acetyl-LL-2,6-diaminoheptanedioate + H2O
acetate + LL-2,6-diaminoheptanedioate
show the reaction diagram
N-acetyl-LL-2,6-diaminopimelic acid + H2O
?
show the reaction diagram
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intermediate in the diaminopimelic acid pathway
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00001
0.00003
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activity in cell extract
60
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wild type strain
80
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strain 1-16
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
gene dapE, DNA determination and analysis, expression in Escherichia coli
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