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Ac-Ala-Thr-Leu-Asn-Phe-Pro-Ile-Ser-Pro-Ile-Glu-NH2 + H2O
Ac-Ala-Thr-Leu-Asn-Phe + Pro-Ile-Ser-Pro-Ile-Glu-NH2
-
-
-
?
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 + H2O
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-OH + Pro-Val-Val-NH2
Ac-Arg-Lys-Ile-Leu-Phe-Leu-Asp-Gly-NH2 + H2O
Ac-Arg-Lys-Ile-Leu + Phe-Leu-Asp-Gly-NH2
-
-
-
-
?
Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 + H2O
Ac-Ser-Gln-Asn-Tyr + Pro-Val-Val-NH2
-
-
-
?
acetyl-Arg-Ala-Ser-Gln-Asn-Tyr-Pro-Val-Val + H2O
acetyl-Arg-Ala-Ser-Gln-Asn-Tyr + Pro-Val-Val
-
-
-
-
?
aminobenzoyl-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2 + H2O
?
-
-
-
-
?
biotin-Gly-Gly-Asp-Arg-Gly-Phe-Ala-Ala-Pro-Gln-Phe-Ser-Leu-Trp-Arg-Arg + H2O
biotin-Gly-Gly-Asp-Arg-Gly-Phe-Ala-Ala + Pro-Gln-Phe-Ser-Leu-Trp-Arg-Arg
-
-
-
?
Lys-Ala-Arg-Val-Nle-(NO2)Phe-Glu-Ala-Nle-Gly + H2O
Lys-Ala-Arg-Val-Nle + (NO2)Phe-Glu-Ala-Nle-Gly
oxidized insulin B chain + H2O
?
-
cleavage sites: HLVE13-ALYL and EALY16-LVC[SO3-]G
-
-
?
Pr55Gag polyprotein + H2O
?
SIV Gag precursor protein + H2O
?
-
determination of cleavage sites and substrate specificity
-
-
?
troponin C + H2O
?
-
cleavage sites: EEEL97-AECF and AEEL117-AEIF
-
-
?
Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val + H2O
Val-Ser-Gln-Asn-Tyr + Pro-Ile-Val
-
-
-
?
additional information
?
-
-
cleavage site in Lys-PE40, a construct based upon the Pseudomonas exotoxin OE66 that is missing domain I are: ANL-1-AEEA and GDAL389-LERN
-
-
?
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 + H2O
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-OH + Pro-Val-Val-NH2
-
-
-
?
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 + H2O
Ac-Arg-Ala-Ser-Gln-Asn-Tyr-OH + Pro-Val-Val-NH2
-
-
-
-
?
galactokinase + H2O
?
-
galactokinase engineered with individual cleavage sites. Cleaves the sites in the order of decreasing preference: Met-Met, Phe-Pro, Leu-Phe, Tyr-Pro, Phe-Leu, Leu-Ala
-
-
?
galactokinase + H2O
?
-
galactokinase engineered with individual cleavage sites. Cleaves the sites in the order of decreasing preference: Met-Met, Phe-Pro, Leu-Phe, Tyr-Pro, Phe-Leu, Leu-Ala
-
-
?
Lys-Ala-Arg-Val-Nle-(NO2)Phe-Glu-Ala-Nle-Gly + H2O
Lys-Ala-Arg-Val-Nle + (NO2)Phe-Glu-Ala-Nle-Gly
-
-
-
?
Lys-Ala-Arg-Val-Nle-(NO2)Phe-Glu-Ala-Nle-Gly + H2O
Lys-Ala-Arg-Val-Nle + (NO2)Phe-Glu-Ala-Nle-Gly
-
-
-
?
Lys-Ala-Arg-Val-Nle-(NO2)Phe-Glu-Ala-Nle-Gly + H2O
Lys-Ala-Arg-Val-Nle + (NO2)Phe-Glu-Ala-Nle-Gly
-
-
-
?
Pr55Gag polyprotein + H2O
?
-
lentiviral Gag polyprotein, proteolytic processing for activation, cleavage in the late stages of life cycle, required for maturation of the virion meaning a structural rearrangement required for infectivity in budding virions, cleavage in the phosphorylated capsid domains, the enzyme is not influenced by the preceeding phosphorylation, but cleaved sites are no longer phosphorylated, while incompletely cleaved capsid domains are phosphorylated to a greater extent, overview
-
-
?
Pr55Gag polyprotein + H2O
?
-
lentiviral Gag polyprotein, cleavage in the phosphorylated capsid domains, the enzyme is not influenced by the preceeding phosphorylation, but cleaved sites are no longer phosphorylated, while incompletely cleaved capsid domains are phosphorylated to a greater extent, overview
-
-
?
Pr55Gag polyprotein + H2O
?
-
PR cleaves Pr55Gag into its constituent domains: matrix (MA), capsid (CA), nucleocapsid (NC), and p6
-
-
?
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Sequence of simian immunodeficiency virus from African green monkey, a new member of HIV/SIV group
Nature
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457-461
1988
Simian immunodeficiency virus (P05895)
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Crystallization and preliminary X-ray investigation of recombinant simian immunodeficiency virus proteinase
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Simian immunodeficiency virus, Simian immunodeficiency virus mac251-32H
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Crystallization and biochemical characterisation of simian immunodeficiency virus proteinase mutant
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Simian immunodeficiency virus
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Substrate specificity of the human (type 1) and simian immunodeficiency virus proteases
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306
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Purification of crystallizable recombinant SIVmac251-32H proteinase
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5
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Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture
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37
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Simian immunodeficiency virus
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Antiviral properties of aminodiol inhibitors against Human immunodeficiency virus and protease
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39
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Alkylation of a catalytic aspartate group of the SIV protease by an epoxide inhibitor
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Simian immunodeficiency virus
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Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particles
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Simian immunodeficiency virus
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Domain flexibility in retroviral proteases: Structural implications for drug resistant mutations
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Simian immunodeficiency virus
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Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease
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Use of protein unfolding studies to determine the conformational and dimeric stabilities of HIV-1 and SIV proteases
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Simian immunodeficiency virus
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Three-dimensional structures of HIV-1 and SIV protease product complexes
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Simian immunodeficiency virus retropepsin
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1
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Phosphorylation and proteolytic cleavage of Gag proteins in budded simian immunodeficiency virus
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The SIVmac239 Pr55Gag isoform, SIV p43, suppresses proteolytic cleavage of Pr55Gag
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