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Flp1 prepilin + H2O
Flp1 pilin + Flp1 prepilin leader peptide
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
pilin type-IV precursor + H2O
pilin type-IV
-
-
-
-
?
PilS2 + H2O
?
-
precursor of the major pilus subunit
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
prepilin type IV + H2O
pilin type IV + leader peptide
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
prePulG + H2O
?
-
processing of proteins which are required for pullulanase secretion
-
-
?
PulG prepseudopilin + H2O
PulG pseudopilin + ?
-
-
-
-
?
T2S prepseudopilin + H2O
?
TadE prepseudopilin + H2O
TadE pseudopilin + TadE prepseudopilin leader peptide
TadF prepseudopilin + H2O
TadF pseudopilin + TadF prepseudopilin leader peptide
TcpA + H2O
?
-
prepilin-containing membrane preparation
-
-
?
type IV Flp1 prepilin + H2O
type IV Flp1 pilin + type IV Flp1 prepilin leader peptide
additional information
?
-
Flp1 prepilin + H2O
Flp1 pilin + Flp1 prepilin leader peptide
-
-
-
-
?
Flp1 prepilin + H2O
Flp1 pilin + Flp1 prepilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pseudopilins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
-
-
-
-
?
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
-
-
-
-
?
Msh prepilin + H2O
?
-
-
-
-
?
Msh prepilin + H2O
?
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
?
prepilin PilA + H2O
?
-
cosynthesis of PilD with its full-length substrate, PilA, leads to complete cleavage of the substrate signal peptides
-
?
prepilin PilA + H2O
?
-
cosynthesis of PilD with its full-length substrate, PilA, leads to complete cleavage of the substrate signal peptides
-
?
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
-
-
-
-
?
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
-
-
-
-
?
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
-
-
-
-
?
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
-
-
-
-
?
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
-
-
-
-
?
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
-
-
-
-
?
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
-
-
-
-
?
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + leader peptide
-
prepilin maturation is required for extracellular protein secretion, and competence state and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
the consensus sequence of the cleavage site is Gly-Phe or Gly-Met within Gly-Phe/Met-Thr-Leu-Ile/Leu-Glu
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
Legionella pneumoniae
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
Legionella pneumoniae
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
the consensus sequence of the cleavage site is Gly-Phe or Gly-Met within Gly-Phe/Met-Thr-Leu-Ile/Leu-Glu
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
the consensus sequence of the cleavage site is Gly-Phe or Gly-Met within Gly-Phe/Met-Thr-Leu-Ile/Leu-Glu
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
T2S prepseudopilin + H2O
?
-
-
-
-
?
T2S prepseudopilin + H2O
?
-
-
-
-
?
TadE prepseudopilin + H2O
TadE pseudopilin + TadE prepseudopilin leader peptide
-
-
-
-
?
TadE prepseudopilin + H2O
TadE pseudopilin + TadE prepseudopilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pilin-like proteins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
TadF prepseudopilin + H2O
TadF pseudopilin + TadF prepseudopilin leader peptide
-
-
-
-
?
TadF prepseudopilin + H2O
TadF pseudopilin + TadF prepseudopilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pilin-like proteins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
type IV Flp1 prepilin + H2O
type IV Flp1 pilin + type IV Flp1 prepilin leader peptide
-
-
-
-
?
type IV Flp1 prepilin + H2O
type IV Flp1 pilin + type IV Flp1 prepilin leader peptide
-
maturation of pilin type IV, the enzyme is involved in the assembly of type IVb pili required for motility and attachment, overview
-
-
?
type IV prepilin + H2O
?
-
-
-
-
?
type IV prepilin + H2O
?
-
-
-
-
?
additional information
?
-
-
activity rate with different recombinant mutants of Flp1, TadE, and TadF constructed by site-directed mutagenesis and expressed in Escherichia coli, overview
-
-
?
additional information
?
-
-
the enzyme is involved in secretion of pullulanase
-
-
?
additional information
?
-
Legionella pneumoniae
-
the enzyme is involved in type II secretion pathway and intracellular survival
-
-
?
additional information
?
-
-
function in protein secretion
-
-
?
additional information
?
-
-
additionally catalyzes the N-methylation of the newly exposed N-terminal amino acid
-
-
?
additional information
?
-
-
additionally catalyzes the N-methylation of the newly exposed N-terminal amino acid
-
-
?
additional information
?
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
the enzyme cleaves sugar-binding proteins unique to Sulfolobus solfataricus
-
-
?
additional information
?
-
-
the enzyme cleaves sugar-binding proteins unique to Sulfolobus solfataricus
-
-
?
additional information
?
-
-
processing by the prepilin peptidase PilD occurs after Gly-1
-
-
?
additional information
?
-
-
processing by the prepilin peptidase PilD occurs after Gly-1
-
-
?
additional information
?
-
-
processing of Eps preplilin-like proteins and Msh prepilins required for cholera toxin secretion
-
-
?
additional information
?
-
-
the loss of PilD significantly reduces the ability of Vibrio vulnificus to persist in Crassostrea virginica over a 66 h interval, strongly suggesting that pili expressed by this bacterium play a role in colonization or persistence in oysters
-
-
?
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Flp1 prepilin + H2O
Flp1 pilin + Flp1 prepilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pseudopilins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
preflagellin + H2O
flagellin + preflagellin leader peptide
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
prepilin type IV + H2O
pilin type IV + leader peptide
-
prepilin maturation is required for extracellular protein secretion, and competence state and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
PulG prepseudopilin + H2O
PulG pseudopilin + ?
-
-
-
-
?
TadE prepseudopilin + H2O
TadE pseudopilin + TadE prepseudopilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pilin-like proteins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
TadF prepseudopilin + H2O
TadF pseudopilin + TadF prepseudopilin leader peptide
-
the enzyme is required for maturation of the Flp1 pilin and TadE and TadF pilin-like proteins which are essential for adhesion of the bacterium to surfaces and formation of strong biofilms
-
-
?
type IV Flp1 prepilin + H2O
type IV Flp1 pilin + type IV Flp1 prepilin leader peptide
-
maturation of pilin type IV, the enzyme is involved in the assembly of type IVb pili required for motility and attachment, overview
-
-
?
additional information
?
-
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
-
-
-
-
?
GspG prepseudopilin + H2O
GspG pseudopilin + GspG prepseudopilin leader peptide
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
-
?
preflagellin + H2O
flagellin + preflagellin leader peptide
-
-
-
?
prepilin PilA + H2O
?
-
cosynthesis of PilD with its full-length substrate, PilA, leads to complete cleavage of the substrate signal peptides
-
?
prepilin PilA + H2O
?
-
cosynthesis of PilD with its full-length substrate, PilA, leads to complete cleavage of the substrate signal peptides
-
?
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
-
-
-
-
?
prepilin PilA + H2O
pilin PilA + prepilin PilA leader peptide
-
-
-
-
?
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
-
-
-
-
?
prepilin PilB + H2O
pilin PilB + prepilin PilB leader peptide
-
-
-
-
?
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
-
-
-
-
?
prepilin PilC + H2O
pilin PilC + prepilin PilC leader peptide
-
-
-
-
?
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
-
-
-
-
?
prepilin PilE1 + H2O
pilin PilE1 + prepilin PilE1 leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
Legionella pneumoniae
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
prepilin type IV + H2O
pilin type IV + prepilin type IV leader peptide
-
prepilin maturation is required for extracellular protein secretion of degradative enzymes and DNA uptake, overview
-
-
?
additional information
?
-
-
the enzyme is involved in secretion of pullulanase
-
-
?
additional information
?
-
Legionella pneumoniae
-
the enzyme is involved in type II secretion pathway and intracellular survival
-
-
?
additional information
?
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
enzyme additionally catalyzes S-adenosyl methionine-dependent methylation of the mature pilin
-
-
?
additional information
?
-
-
processing by the prepilin peptidase PilD occurs after Gly-1
-
-
?
additional information
?
-
-
processing by the prepilin peptidase PilD occurs after Gly-1
-
-
?
additional information
?
-
-
the loss of PilD significantly reduces the ability of Vibrio vulnificus to persist in Crassostrea virginica over a 66 h interval, strongly suggesting that pili expressed by this bacterium play a role in colonization or persistence in oysters
-
-
?
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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A129V
-
random mutagenesis, DNA sequence determination, inactive mutant
A92V
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
C170R
-
random mutagenesis, DNA sequence determination, inactive mutant
C200R
-
random mutagenesis, DNA sequence determination, inactive mutant
D151N
-
random mutagenesis, DNA sequence determination, inactive mutant
D91N
-
random mutagenesis, DNA sequence determination, inactive mutant
E125G
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
F101L
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
F30Y
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
G95D
-
random mutagenesis, DNA sequence determination, inactive mutant
H76L
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
H76R
-
random mutagenesis, DNA sequence determination, inactive mutant
I114N
-
random mutagenesis, DNA sequence determination, inactive mutant
I23T
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
I24V
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
K138R
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
K188R
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
K191E
-
random mutagenesis, DNA sequence determination, inactive mutant
K45R
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
L136P
-
random mutagenesis, DNA sequence determination, inactive mutant
L66S
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
L81P
-
random mutagenesis, DNA sequence determination, inactive mutant
L93P
-
random mutagenesis, DNA sequence determination, inactive mutant
L96S
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
L97I
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
L97S
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
M110R
-
random mutagenesis, DNA sequence determination, inactive mutant
M87K
-
random mutagenesis, DNA sequence determination, inactive mutant
N210D
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
Q86R
-
random mutagenesis, DNA sequence determination, inactive mutant
S112P
-
random mutagenesis, DNA sequence determination, inactive mutant
S82L
-
random mutagenesis, DNA sequence determination, inactive mutant
T102A
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
T128N
-
random mutagenesis, DNA sequence determination, inactive mutant
V132D
-
random mutagenesis, DNA sequence determination, inactive mutant
V140D
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
W153R
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
W161R
-
random mutagenesis, DNA sequence determination, inactive mutant
W169G
-
random mutagenesis, DNA sequence determination, reduced activity compared to the wild-type enzyme
W185R
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
W55R
-
random mutagenesis, DNA sequence determination, inactive mutant
Y212C
-
random mutagenesis, DNA sequence determination, highly reduced activity compared to the wild-type enzyme
D17A
-
site-directed mutagenesis, inactive mutant
D17A/D78A
-
site-directed mutagenesis, inactive mutant
D78A
-
site-directed mutagenesis, inactive mutant
D157A
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme
D173A
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme
D180A
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme
D187A
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
D187A/D188A
site-directed mutagenesis, inactive mutant
D188A
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
D207N
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme
D23A
site-directed mutagenesis, inactive mutant
D30A
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme
D80A
site-directed mutagenesis, inactive mutant
D80E
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
C51A
-
activity identical to wild-type
C73A
-
activity identical to wild-type
C76A
-
activity identical to wild-type
D125A
-
no peptidase activity
D125E
-
partial peptidase activity
D125N
-
no peptidase activity
D183N
-
activity identical to wild-type
D189E
-
partial peptidase activity
D189N
-
no peptidase activity
D198A
-
no peptidase activity
E88A
-
activity identical to wild-type
K191A
-
activity identical to wild-type
S172A
-
activity identical to wild-type
S18A
-
activity identical to wild-type
S46A
-
activity identical to wild-type
S65A
-
activity identical to wild-type
S81L
-
activity identical to wild-type
additional information
-
effects of mutations on membrane topology of mutants, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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Lory, S.; Strom, M.S.
Structure-function relationship of type-IV prepilin peptidase of Pseudomonas aeruginosa
Gene
192
117-121
1997
Pseudomonas aeruginosa
brenda
LaPointe, C.F.; Taylor, R.K.
The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases
J. Biol. Chem.
275
1502-1510
2000
Vibrio cholerae serotype O1
brenda
Bally, M.; Filloux, A.; Akrim, M.; Ball, G.; Lazdunski, A.; Tommassen, J.
Protein secretion in Pseudomonas aeruginosa: characterization of seven xcp genes and processing of secretory apparatus components by prepilin peptidase
Mol. Microbiol.
6
1121-1131
1992
Pseudomonas aeruginosa
brenda
Liles, M.R.; Edelstein, P.H.; Cianciotto, N.P.
The prepilin peptidase is required for protein secretion by and the virulence of the intracellular pathogen Legionella pneumophila
Mol. Microbiol.
31
959-970
1999
Legionella pneumophila
brenda
Marsh, J.W.; Taylor, R.K.
Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation
Mol. Microbiol.
29
1481-1492
1998
Vibrio cholerae serotype O1
brenda
Pugsley, A.P.; Dupuy, B.
An enzyme with type IV prepilin peptidase activity is required to process components of the general extracellular protein secretion pathway of Klebsiella oxytoca
Mol. Microbiol.
6
751-760
1992
Klebsiella oxytoca
brenda
Nunn, D.N.; Lory, S.
Components of the protein-excretion apparatus of Pseudomonas aeruginosa are processed by the type IV prepilin peptidase
Proc. Natl. Acad. Sci. USA
89
47-51
1992
Pseudomonas aeruginosa, Pseudomonas aeruginosa mutant
brenda
Dupuy, B.; Deghmane, A.; Taha, M.
Type IV prepilin peptidase
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. )
1
204-208
2004
Bacillus subtilis, Escherichia coli, Dickeya chrysanthemi, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Xanthomonas campestris, Vibrio vulnificus, Legionella pneumoniae, Vibrio cholerae serotype O1
-
brenda
Szabo, Z.; Albers, S.V.; Driessen, A.J.
Active-site residues in the type IV prepilin peptidase homologue PibD from the archaeon Sulfolobus solfataricus
J. Bacteriol.
188
1437-1443
2006
Saccharolobus solfataricus (Q6IFS8), Saccharolobus solfataricus
brenda
de Bentzmann, S.; Aurouze, M.; Ball, G.; Filloux, A.
FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili
J. Bacteriol.
188
4851-4860
2006
Pseudomonas aeruginosa
brenda
Tomich, M.; Fine, D.H.; Figurski, D.H.
The TadV protein of Actinobacillus actinomycetemcomitans is a novel aspartic acid prepilin peptidase required for maturation of the Flp1 pilin and TadE and TadF pseudopilins
J. Bacteriol.
188
6899-6914
2006
Aggregatibacter actinomycetemcomitans
brenda
Akahane, K.; Sakai, D.; Furuya, N.; Komano, T.
Analysis of the pilU gene for the prepilin peptidase involved in the biogenesis of type IV pili encoded by plasmid R64
Mol. Genet. Genomics
273
350-359
2005
Escherichia coli
brenda
Paranjpye, R.N.; Johnson, A.B.; Baxter, A.E.; Strom, M.S.
Role of type IV pilins in persistence of Vibrio vulnificus in Crassostrea virginica oysters
Appl. Environ. Microbiol.
73
5041-5044
2007
Vibrio vulnificus
brenda
Ng, S.Y.; Chaban, B.; Jarrell, K.F.
Archaeal flagella, bacterial flagella and type IV pili: a comparison of genes and posttranslational modifications
J. Mol. Microbiol. Biotechnol.
11
167-191
2006
Escherichia coli, Methanococcus maripaludis, Methanococcus voltae, Pseudomonas aeruginosa, Saccharolobus solfataricus
brenda
Bernard, C.S.; Bordi, C.; Termine, E.; Filloux, A.; de Bentzmann, S.
Organization and PprB-dependent control of the Pseudomonas aeruginosa tad Locus, involved in Flp pilus biology
J. Bacteriol.
191
1961-1973
2009
Pseudomonas aeruginosa (P22610), Pseudomonas aeruginosa
brenda
Bouhenni, R.; Vora, G.; Biffinger, J.; Shirodkar, S.; Brockman, K.; Ray, R.; Wu, P.; Johnson, B.; Biddle, E.; Marshall, M.; Fitzgerald, L.; Little, B.; Fredrickson, J.; Beliaev, A.; Ringeisen, B.; Saffarini, D.
The role of Shewanella oneidensis MR-1 outer surface structures in extracellular electron transfer
Electroanalysis
22
856-864
2010
Shewanella oneidensis, Shewanella oneidensis MR-1 / ATCC 700550
-
brenda
Carter, M.Q.; Chen, J.; Lory, S.
The Pseudomonas aeruginosa pathogenicity island PAPI-1 is transferred via a novel type IV pilus
J. Bacteriol.
192
3249-3258
2010
Pseudomonas aeruginosa
brenda
Aly, K.A.; Beebe, E.T.; Chan, C.H.; Goren, M.A.; Sepulveda, C.; Makino, S.; Fox, B.G.; Forest, K.T.
Cell-free production of integral membrane aspartic acid proteases reveals zinc-dependent methyltransferase activity of the Pseudomonas aeruginosa prepilin peptidase PilD
MicrobiologyOpen
2
94-104
2013
Pseudomonas aeruginosa (P22610), Pseudomonas aeruginosa, Pseudomonas aeruginosa ATCC 15692 (P22610)
brenda
Linhartova, M.; Bucinska, L.; Halada, P.; Jecmen, T.; Setlik, J.; Komenda, J.; Sobotka, R.
Accumulation of the Type IV prepilin triggers degradation of SecY and YidC and inhibits synthesis of Photosystem II proteins in the cyanobacterium Synechocystis PCC 6803
Mol. Microbiol.
93
1207-1223
2014
Synechocystis sp. (P72640), Synechocystis sp.
brenda
Gimenez, M.; Cerletti, M.; De Castro, R.
Archaeal membrane-associated proteases Insights on Haloferax volcanii and other haloarchaea
Front. Microbiol.
6
39
2015
Haloferax volcanii, Saccharolobus solfataricus
brenda
Berry, J.L.; Gurung, I.; Anonsen, J.H.; Spielman, I.; Harper, E.; Hall, A.M.J.; Goosens, V.J.; Raynaud, C.; Koomey, M.; Biais, N.; Matthews, S.; Pelicic, V.
Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis
J. Biol. Chem.
294
6796-6808
2019
Streptococcus sanguinis, Streptococcus sanguinis 2908
brenda
Santos-Moreno, J.; East, A.; Guilvout, I.; Nadeau, N.; Bond, P.J.; Tran Van Nhieu, G.; Francetic, O.
Polar N-terminal residues conserved in type 2 secretion pseudopilins determine subunit targeting and membrane extraction steps during fibre assembly
J. Mol. Biol.
429
1746-1765
2017
Klebsiella oxytoca
brenda
Harding, C.M.; Kinsella, R.L.; Palmer, L.D.; Skaar, E.P.; Feldman, M.F.
Medically relevant Acinetobacter species require a type II secretion system and specific membrane-associated chaperones for the export of multiple substrates and full virulence
PLoS Pathog.
12
e1005391
2016
Acinetobacter nosocomialis, Acinetobacter nosocomialis M2
brenda