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(2R,2'R,2''R,2'''R,3S,3'S,3''S,3'''S,4S,4'S,4''R)-2,2',2'''-tris(3,4-dihydroxyphenyl)-2''-(4-hydroxyphenyl)-3,3',3'',3''',4,4',4'',4'''-octahydro-2H,2'H,2''H,2'''H-4,8':4',8'':4'',8'''-quaterchromene-3,3',3'',3''',5,5',5'',5''',7,7',7'',7'''-dodecol
-
-
(2R,2'R,2''R,3S,3'S,3''S,4S,4'R)-2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-2H,2'H,2''H-4,8':4',8''-terchromene-3,3',3'',5,5',5'',7,7',7''-nonol
-
-
1-O-(3-O-sulfo-beta-D-galactopyranosyl)-ceramide
-
0.001 mg elastase in 0.01 ml of 50 mM HEPES buffer at pH 7.5 with 0.01 mg inhibitor in 0.01 ml DMSO at 37° for 30 min
3,4-dichloroisocoumarin
-
-
3-Phenylpropionic acid
-
-
4-([(S)-1-[((S)-2-[[(RS)-3,3,3-trifluoro-1-isopropyl-2-oxopropyl]aminocarbonyl]pyrrolidin-1-yl-)carbonyl]-2-methylpropyl]aminocarbonyl)benzoic acid
-
Alpha1-proteinase inhibitor
-
-
alpha2-Macroglobulin
-
-
-
Bovine pancreatic trypsin inhibitor
-
-
Cholesterol sulfate
-
0.001 mg elastase in 0.09 ml of 50 mM HEPES buffer at pH 7.5 with 0.01 mg inhibitor in 0.01 ml DMSO at 37° for 30 min
diisopropyl fluorophosphate
FR130180
i.e. 4-([(S)-1-[((S)-2-[[(RS)-3,3,3-trifluoro-1-isopropyl-2-oxopropyl]-aminocarbonyl]pyrrolidin-1yl)carbonyl]-2-methylpropyl]aminocarbonyl) benzoic acid
FR136706
potent inhibitor
largamide A methyl ester
-
low-micromolar inhibitory activity
largamide B methyl ester
-
low-micromolar inhibitory activity
largamide C methyl ester
-
low-micromolar inhibitory activity
N-(trifluoroacetyl)-alpha-aspartyl-N-[4-(trifluoromethyl)phenyl]alaninamide
-
reversible inhibitor
N-(trifluoroacetyl)-Phe-Ala 4-(trifluoromethyl)anilide
-
-
N-(trifluoroacetyl)-Val-Ala 4-(trifluoromethyl)anilide
-
-
N-(trifluoroacetyl)leucyl-N-[4-(trifluoromethyl)phenyl]alaninamide
-
reversible inhibitor
N-(trifluoroacetyl)valyl-N-[4-(trifluoromethyl)phenyl]alaninamide
-
reversible inhibitor
N-benzyl-2-oxo-4-(phenylsulfonyl)azetidine-1-carboxamide
-
JM54, potent and irreversible inhibitor
N2-(trifluoroacetyl)lysyl-N-[4-(trifluoromethyl)phenyl]alaninamide
-
reversible inhibitor
NaCl
-
elastase 1: slight inhibition above 150 mM, elastase 2: 25-250 mM, activation
Pancreatic trypsin inhibitor
-
-
-
phenylmethanesulfonyl fluoride
Schistocerca gregaria proteinase inhibitor 2 variant E1
-
Schistocerca gregaria proteinase inhibitor 2 variant E10
-
Schistocerca gregaria proteinase inhibitor 2 variant E11
-
Schistocerca gregaria proteinase inhibitor 2 variant E12
-
Schistocerca gregaria proteinase inhibitor 2 variant E2
-
Schistocerca gregaria proteinase inhibitor 2 variant E3
-
Schistocerca gregaria proteinase inhibitor 2 variant E4
-
Schistocerca gregaria proteinase inhibitor 2 variant E5
-
Schistocerca gregaria proteinase inhibitor 2 variant E6
-
Schistocerca gregaria proteinase inhibitor 2 variant E7
-
Schistocerca gregaria proteinase inhibitor 2 variant E8
-
Schistocerca gregaria proteinase inhibitor 2 variant E9
-
scyptolin A
the inhibitor occupies the most prominent subsites S1 through S4 of the elastase and prevents a hydrolytic attack by covering the active center with its rigid ring structure
SDS
-
0.001 mg elastase in 0.09 ml of 50 mM HEPES buffer at pH 7.5 with 0.01 mg inhibitor in 0.01 ml DMSO at 37° for 30 min
serpin
active site distortion is sufficient for proteinase inhibition by serpins
-
Soybean trypsin inhibitor
-
tiglicamide A
-
moderate inhibition of porcine pancreatic elastase in vitro
tiglicamide B
-
moderate inhibition of porcine pancreatic elastase in vitro
tiglicamide C
-
moderate inhibition of porcine pancreatic elastase in vitro
tosyl-L-phenylalanyl chloromethylketone
-
-
viral serpin crmA
-
pancreatic elastase is rapidly inhibited by wild-type crmA and reactive loop variant P1 Arg crmAs
-
diisopropyl fluorophosphate
-
-
diisopropyl fluorophosphate
-
-
diisopropyl fluorophosphate
Thunnus albacora
-
-
EETI II
-
trypsin-specific squash inhibitor from Ecballium elaterium
-
EETI II
trypsin-specific squash inhibitor from Ecballium elaterium
-
elafin
-
-
-
Elastinal
-
-
HEI-TOE I
-
hybrid inhibitor from Ecballium elaterium and the optimized binding loop of the third domain of turkey ovomucoid inhibitor
-
HEI-TOE I
hybrid inhibitor from Ecballium elaterium and the optimized binding loop of the third domain of turkey ovomucoid inhibitor
-
OMTKY3
-
third Kazal-type domain of ovomucoid inhibitor from turkey egg white
-
OMTKY3
third Kazal-type domain of ovomucoid inhibitor from turkey egg white
-
PACTLEYRC
-
-
phenylmethanesulfonyl fluoride
-
-
phenylmethanesulfonyl fluoride
-
-
phenylmethanesulfonyl fluoride
Thunnus albacora
-
-
PMTLEYR
-
-
Schistocerca gregaria proteinase inhibitor 2 variant E1
-
Tyr-Cys-Thr-Leu-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E1
-
Tyr-Cys-Thr-Leu-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E10
-
Ala-Cys-Thr-Leu-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E10
-
Ala-Cys-Thr-Leu-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E11
-
Ala-Cys-Thr-Leu-Met-Tyr-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E11
-
Ala-Cys-Thr-Leu-Met-Tyr-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E12
-
Tyr-Cys-Thr-Leu-Met-Leu-Cys-Ala
-
Schistocerca gregaria proteinase inhibitor 2 variant E12
-
Tyr-Cys-Thr-Leu-Met-Leu-Cys-Ala
-
Schistocerca gregaria proteinase inhibitor 2 variant E2
-
Tyr-Cys-Thr-Ile-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E2
-
Tyr-Cys-Thr-Ile-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E3
-
Tyr-Cys-Thr-Val-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E3
-
Tyr-Cys-Thr-Val-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E4
-
Tyr-Cys-Thr-Met-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E4
-
Tyr-Cys-Thr-Met-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E5
-
Tyr-Cys-Thr-Ala-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E5
-
Tyr-Cys-Thr-Ala-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E6
-
Tyr-Cys-Thr-Ser-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E6
-
Tyr-Cys-Thr-Ser-Met-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E7
-
Tyr-Cys-Thr-Ile-Met-Glu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E7
-
Tyr-Cys-Thr-Ile-Met-Glu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E8
-
Tyr-Cys-Thr-Leu-Arg-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E8
-
Tyr-Cys-Thr-Leu-Arg-Leu-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E9
-
Tyr-Cys-Thr-Leu-Met-Tyr-Cys-His
-
Schistocerca gregaria proteinase inhibitor 2 variant E9
-
Tyr-Cys-Thr-Leu-Met-Tyr-Cys-His
-
Soybean trypsin inhibitor
-
-
-
Soybean trypsin inhibitor
-
-
-
Soybean trypsin inhibitor
-
-
-
additional information
-
serum from normal volunteers and patients with alpha 1-antitrypsin deficiency completely inactivate PRT-201 elastase activity in vitro
-
additional information
-
-
-
additional information
-
-
-
additional information
-
not inhibited by dehydroepiandrosterone sulfate, pregnenolone sulfate, cholesterol, oleic acid, triolein, phosphatidylethanolamine, phosphatidylcholine, phosphatidylserine, sphingomyelin, GalCer, LacCer
-
additional information
-
the peptide RC-12 does not inhibit pancreatic elastase at concentrations up to 0.1 mM
-
additional information
-
an oligomeric fraction of procyanidins shows about 90% inhibition at 0.2 mM
-
additional information
not inhibited by ShPI-1
-
additional information
-
not inhibited by ShPI-1
-
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Human pancreatic enzymes: purification and characterization of a nonelastolytic enzyme, protease E. resembling elastase
Biochemistry
14
722-730
1975
Homo sapiens
brenda
Szilagyi, C.M.; Sarfati, P.; Pradayrol, L.; Morisset, J.
Purification, characterization and substrate specificity of rat pancreatic elastase II
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Rattus norvegicus
brenda
Powers, J.C.; Gupton, B.F.; Harley, A.D.; Nishino, N.; Whitley, R.J.
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Biochim. Biophys. Acta
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Sus scrofa
brenda
Largman, C.
Isolation and characterization of rat pancreatic elastase
Biochemistry
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1983
Rattus norvegicus
brenda
Fujimoto, K.; Ogawa, M.; Saito, N.; Kosaki, G.; Minamiura, N.; Yamamoto, T.
A novel method of isolation and some characteristic properties of human pancreatic elastases
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Homo sapiens
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Katagiri, K.; Takeuchi, T.; Taniguchi, K.; Sasaki, M.
One step purification procedure of elastase from pancreatic powder by affinity chromatography
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1978
Sus scrofa
brenda
Ohlsson, K.; Olsson, A.S.
Purification and partial characterization of human pancreatic elastase
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357
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1976
Homo sapiens
brenda
Largman, C.; Brodrick, J.W.; Geokas, M.C.
Purification and characterization of two human pancreatic elastases
Biochemistry
15
2491-2500
1976
Homo sapiens
brenda
Ardelt, W.
Partial purification and properties of porcine pancreatic elastase II
Biochim. Biophys. Acta
341
318-326
1974
Sus scrofa
brenda
Tsunemi, M.; Matsuura, Y.; Sakakibara, S.; Katsube, Y.
Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution
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35
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1996
Sus scrofa (P00772), Sus scrofa
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Tsunemi, M.; Matsuura, Y.; Sakakibara, S.; Katsube, Y.
Crystallization of a complex between an elastase-specific inhibitor elafin and porcine pancreatic elastase
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1993
Sus scrofa
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Erlendsson, L.S.; Filippsusson, H.
Purification and characterization of ovine pancreatic elastase
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120
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1998
Ovis aries
brenda
Berglund, G.I.; Smalas, A.O.; Outzen, H.; Willassen, N.P.
Purification and characterization of pancreatic elastase from North Atlantic salmon (Salmo salar)
Mol. Mar. Biol. Biotechnol.
7
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brenda
Wendorf, P.; Linder, D.; Sziegoleit, A.; Geyer, R.
Carbohydrate structure of human pancreatic elastase 1
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278
505-514
1991
Homo sapiens
brenda
Smine, A.; Gal, Y.L.
Purification and characterization of two pancreatic elastase isoforms from dogfish (Scyliorhinus canicula)
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4
295-303
1995
Scyliorhinus canicula
brenda
Smine, A.; Guerard, F.; Gal, Y.L.
Purification and characterization of pancreatic elastase from tuna (Thunnus albacora)
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1
41-46
1993
Thunnus albacora
-
brenda
Berglund, G.I.; Willassen, N.P.; Hordvik, A.; Smalas, A.O.
Structure of native pancreatic elastase from north atlantic salmon at 1.6 A resolution
Acta Crystallogr. Sect. D
51
925-937
1995
Salmo salar
brenda
Mattos, C.; Gianmmona, D.A.; Petsko, G.A.; Ringe, D.
Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors
Biochemistry
34
3193-3203
1995
Sus scrofa
brenda
Bode, W.; Meyer Jr., E.; Powers, J.C.
Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors
Biochemistry
28
1951-1963
1989
Sus scrofa
brenda
Wendorf, P.; Geyer, R.; Sziegoleit, A.; Linder, D.
Localization and characterization of the glycosylation site of human pancreatic elastase 1
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249
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1989
Homo sapiens
brenda
Gildberg, A.; Overbo, K.
Purification and characterization of pancreatic elastase from Atlantic cod (Gadus morhua)
Comp. Biochem. Physiol. B
97
775-782
1990
Gadus morhua
brenda
Plaskon, R.R.; Kam, C.M.; Burgess, E.M.; Powers, J.C.; Suddath, F.L.
Michaelis complexes of porcine pancreatic elastase with 7-[(alkylcarbamoyl)amino]-4-chloro-3-ethoxyisocoumarins: translational sampling of inhibitor position and kinetic measurements
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13
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1992
Sus scrofa
brenda
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Atomic resolution structure of native porcine pancreatic elastase at 1.1 A
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56
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2000
Sus scrofa
-
brenda
Hilpert, K.; Schneider-Mergener, J.; Ay, J.
Crystallization and preliminary X-ray analysis of the complex of porcine pancreatic elastase and a hybrid squash inhibitor
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58
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2002
Sus scrofa (P00772), Sus scrofa
brenda
Ay, J.; Hilpert, K.; Krauss, N.; Schneider-Mergener, J.; Hohne, W.
Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution
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59
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2003
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brenda
Jaspard, E.
Role of protein-solvent interactions in refolding. Effects of cosolvent additives on the renaturation of porcine pancreatic elastase at various pHs
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375
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2000
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'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes
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351
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2000
Sus scrofa
-
brenda
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True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor
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13
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2003
Sus scrofa (P00772), Sus scrofa
brenda
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Binding structure of elastase inhibitor scyptolin A
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10
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brenda
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Design and characterization of a hybrid miniprotein that specifically inhibits porcine pancreatic elastase
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Inhibition of pancreatic elastase by sulfated lipids in the intestinal mucosa
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Tris(hydroxymethyl)aminomethane induces conformational change and crystal-packing contraction of porcine pancreatic elastase
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623-626
2006
Sus scrofa, Sus scrofa (P00772)
brenda
Dementiev, A.; Dobo, J.; Gettins, P.G.
Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase
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281
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Crystallization and preliminary X-ray analysis of complexes of porcine pancreatic elastase with two natural inhibitors
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11
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2004
Sus scrofa
brenda
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Specificity and reactive loop length requirements for crmA inhibition of serine proteases
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14
533-542
2005
Sus scrofa
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Kinoshita, T.; Tamada, T.; Imai, K.; Kurihara, K.; Ohhara, T.; Tada, T.; Kuroki, R.
Crystallization of porcine pancreatic elastase and a preliminary neutron diffraction experiment
Acta Crystallogr. Sect. F
63
315-317
2007
Sus scrofa (P00772), Sus scrofa
brenda
Walkowiak, J.; Wadolowska, L.; Szaflarska-Poplawska, A.; Lisowska, A.; Bugajewska, A.; Przyslawski, J.
The elimination of meat from the diet selectively decreases pancreatic elastase secretion
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98
154-158
2007
Homo sapiens
brenda
Chen, C.Y.; Tsai, W.L.; Wu, H.C.; Syu, M.J.; Wu, C.C.; Shiesh, S.C.
Diagnostic role of biliary pancreatic elastase for cholangiocarcinoma in patients with cholestasis
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390
82-89
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Homo sapiens (Q9UNI1), Homo sapiens
brenda
Naruse, S.; Ishiguro, H.; Ko, S.B.; Yoshikawa, T.; Yamamoto, T.; Yamamoto, A.; Futakuchi, S.; Goto, H.; Saito, Y.; Takahashi, S.
Fecal pancreatic elastase: a reproducible marker for severe exocrine pancreatic insufficiency
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41
901-908
2006
Homo sapiens
brenda
Oliveira, T.F.; Mulchande, J.; Moreira, R.; Iley, J.; Archer, M.
Crystallization and preliminary diffraction studies of porcine pancreatic elastase in complex with a novel inhibitor
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14
93-95
2007
Sus scrofa
brenda
Benahmed, N.A.; Manene, D.; Barbot, L.; Kapel, N.
Fecal pancreatic elastase in infants under 2 years of age
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66
549-552
2008
Homo sapiens
brenda
Erickson, J.A.; Aldeen, W.E.; Grenache, D.G.; Ashwood, E.R.
Evaluation of a fecal pancreatic elastase-1 enzyme-linked immunosorbent assay: Assessment versus an established assay and implication in classifying pancreatic function
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397
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2008
Homo sapiens
brenda
Nadarajah, D.; Atkinson, M.A.; Huebner, P.; Starcher, B.
Enzyme kinetics and characterization of mouse pancreatic elastase
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49
409-415
2008
Mus musculus
brenda
Suzuki, M.; Betsuyaku, T.; Ito, Y.; Nagai, K.; Odajima, N.; Moriyama, C.; Nasuhara, Y.; Nishimura, M.
Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice
Am. J. Physiol. Lung Cell Mol. Physiol.
296
L614-L623
2009
Sus scrofa
brenda
Conlon, J.M.; Raza, H.; Coquet, L.; Jouenne, T.; Leprince, J.; Vaudry, H.; King, J.D.
Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)
Comp. Biochem. Physiol. C
150
150-154
2009
Sus scrofa
brenda
Tamada, T.; Kinoshita, T.; Kurihara, K.; Adachi, M.; Ohhara, T.; Imai, K.; Kuroki, R.; Tada, T.
Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond
J. Am. Chem. Soc.
131
11033-11040
2009
Sus scrofa (P00772), Sus scrofa
brenda
Inoue, K.; Koike, E.; Yanagisawa, R.; Takano, H.
Extensive analysis of elastase-induced pulmonary emphysema in rats: ALP in the lung, a new biomarker for disease progression?
J. Clin. Biochem. Nutr.
46
168-176
2010
Sus scrofa
brenda
Kwan, J.C.; Taori, K.; Paul, V.J.; Luesch, H.
Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena
Mar. Drugs
7
528-538
2009
Sus scrofa
brenda
Rietschel, B.; Arrey, T.; Meyer, B.; Bornemann, S.; Schuerken, M.; Karas, M.; Poetsch, A.
Elastase digests: New ammunition for shotgun membrane proteomics
Mol. Cell. Proteomics
8
1029-1043
2009
Sus scrofa (P00772), Sus scrofa
brenda
Matthew, S.; Paul, V.J.; Luesch, H.
Tiglicamides A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides
Phytochemistry
70
2058-2063
2009
Sus scrofa
brenda
Bras, N.F.; Goncalves, R.; Fernandes, P.A.; Mateus, N.; Ramos, M.J.; de Freitas, V.
Understanding the binding of procyanidins to pancreatic elastase by experimental and computational methods
Biochemistry
49
5097-5108
2010
Sus scrofa
brenda
Herzig, K.; Purhonen, A.; Rsnen, K.; Idziak, J.; Juvonen, P.; Phillps, R.; Walkowiak, J.
Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus
BMC Geriatr.
11
4-4
2011
Homo sapiens
brenda
Bras, N.F.; Goncalves, R.; Mateus, N.; Fernandes, P.A.; Ramos, M.J.; de Freitas, V.
Inhibition of pancreatic elastase by polyphenolic compounds
J. Agric. Food Chem.
58
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2010
Sus scrofa
brenda
Qamar, A.A.; Burke, S.K.; Lafleur, J.D.; Ding, B.C.; Bland, K.S.; Wong, M.D.; Gustafson, P.N.; Blair, A.T.; Franano, F.N.
The ability of serum from alpha 1-antitrypsin-deficient patients to inhibit PRT-201, a recombinant human type I pancreatic elastase
Biotechnol. Appl. Biochem.
59
22-28
2012
Homo sapiens
brenda
Qasim, M.A.; Wang, L.; Qasim, S.; Lu, S.; Lu, W.; Wynn, R.; Yi, Z.P.; Laskowski, M.
Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB)
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3021-3026
2013
Sus scrofa
brenda
Burke, S.K.; Macdonald, K.; Moss, E.; Bunton, D.; Starcher, B.; Wong, M.D.; Bland, K.S.; Franano, F.N.
Effects of recombinant human type I pancreatic elastase on human atherosclerotic arteries
J. Cardiovasc. Pharmacol.
64
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2014
Homo sapiens
brenda
Hofbauer, S.; Brito, J.A.; Mulchande, J.; Nogly, P.; Pessanha, M.; Moreira, R.; Archer, M.
Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking
Acta Crystallogr. Sect. F
71
1346-1351
2015
Sus scrofa
brenda
Sadeghi-Kaji, S.; Shareghi, B.; Saboury, A.A.; Farhadian, S.
Spectroscopic and molecular docking studies on the interaction between spermidine and pancreatic elastase
Int. J. Biol. Macromol.
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473-483
2019
Sus scrofa
brenda
Boros, E.; Szabo, A.; Zboray, K.; Heja, D.; Pal, G.; Sahin-Toth, M.
Overlapping specificity of duplicated human pancreatic elastase 3 isoforms and archetypal porcine elastase 1 provides clues to evolution of digestive enzymes
J. Biol. Chem.
292
2690-2702
2017
Homo sapiens, Sus scrofa
brenda
Stergiou, P.Y.; Foukis, A.; Gkini, O.A.; Bieth, J.G.; Papamichael, E.M.
Kinetic and computational analysis of the reversible inhibition of porcine pancreatic elastase a structural and mechanistic approach
J. Enzyme Inhib. Med. Chem.
31
131-139
2016
Sus scrofa
brenda
Hernandez Gonzalez, J.E.; Garcia-Fernandez, R.; Valiente, P.A.
Polar desolvation and position 226 of pancreatic and neutrophil elastases are crucial to their affinity for the Kunitz-Type inhibitors ShPI-1 and ShPI-1/K13L
PLoS ONE
10
e0137787
2015
Sus scrofa (P00772), Sus scrofa
brenda