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Information on EC 3.1.4.14 - [acyl-carrier-protein] phosphodiesterase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.4 Phosphoric-diester hydrolases
                3.1.4.14 [acyl-carrier-protein] phosphodiesterase
IUBMB Comments
The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl chains of 6-16 carbon atoms although it appears to demonstrate a preference for the unacylated acyl-carrier protein (ACP) and short-chain ACPs over the medium- and long-chain species . Deletion of the gene encoding this enzyme abolishes ACP prosthetic-group turnover in vivo . Activation of apo-ACP to form the holoenzyme is carried out by EC 2.7.8.7, holo-[acyl-carrier-protein] synthase.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
acyl carrier protein phosphodiesterase, acp phosphodiesterase, 4'-phosphopantetheine hydrolase, acp hydrolyase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
holo-[acyl-carrier protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier protein]
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PATHWAY SOURCE
PATHWAYS
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