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Information on EC 3.1.1.85 - pimelyl-[acyl-carrier protein] methyl ester esterase

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EC Tree
IUBMB Comments
Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains [1,2]. Even though the enzyme can interact with coenzyme A thioesters , the in vivo role of the enzyme is to hydrolyse the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalysed by the fatty acid elongation enzymes .
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
bioh protein, pimeloyl-acp methyl esterase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pimeloyl-[acyl-carrier protein] methyl ester + H2O = pimeloyl-[acyl-carrier protein] + methanol
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PATHWAY SOURCE
PATHWAYS
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