Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1-stearoyl-2-arachidonoylphosphatidylinositol + CMP
CDP-1-stearoyl-2-arachidonoylglycerol + myo-inositol
-
-
-
r
2-deoxy-CDP-diacylglycerol + myo-inositol
CMP + ?
CDP-1-arachidonoyl-2-stearoylglycerol + myo-inositol
CMP + 1-arachidonoyl-2-stearoylphosphtidylinositol
-
6% of the activity with CDP-1-stearoyl-2-oleoylglycerol
-
-
r
CDP-1-stearoyl-2-arachidonoylglycerol + myo-inositol
CMP + 1-stearoyl-2-arachidonoylphosphatidylinositol
-
4% of the activity with CDP-1-stearoyl-2-oleoylglycerol
-
-
r
CDP-1-stearoyl-2-oleoylglycerol + myo-inositol
CMP + 1-stearoyl-2-oleoylphosphatidylinositol
-
-
-
-
r
CDP-diacylglycerol + 1D-chiro-inositol
CMP + phosphatidyl-1D-chiro-inositol
-
conversion of 30.9% CDP-diacylglycerol (utilization significant compared to background, p: 0.05), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + 1L-chiro-inositol
CMP + phosphatidyl-1L-chiro-inositol
-
conversion of 25.1% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + allo-inositol
CMP + phosphatidyl-allo-inositol
CDP-diacylglycerol + D-chiro-inositol
CMP + phosphatidyl-chiro-inositol
-
82% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + D-myo-inositol
CMP + phosphatidyl-1D-myo-inositol
CDP-diacylglycerol + epi-inositol
CMP + phosphatidyl-epi-inositol
CDP-diacylglycerol + L-chiro-inositol
CMP + phosphatidyl-chiro-inositol
-
67% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + muco-inositol
CMP + phosphatidyl-muco-inositol
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-myo-inositol
CDP-diacylglycerol + scyllo-inositol
CMP + phosphatidyl-scyllo-inositol
CDP-diarachidonoylglycerol + myo-inositol
CMP + diarachidonoylphosphatidylinositol
-
9% of the activity with CDP-1-stearoyl-2-oleoylglycerol
-
-
r
CDP-didecanoyl-sn-glycerol + myo-inositol
CMP + didecanoylphosphatidylinositol
-
preferred substrate
-
-
r
CDP-diheptadecanoylglycerol + D-myo-inositol
CMP + 1,2-diheptadecanoyl-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-dilinoleoylglycerol + D-myo-inositol
CMP + 1,2-dilinoleoyl-phosphatidyl-1D-myo-inositol
CDP-dioleoylglycerol + D-myo-inositol
CMP + 1,2-dioleoyl-phosphatidyl-1D-myo-inositol
CDP-dioleoylglycerol + myo-inositol
CMP + dioleoylphosphatidylinositol
CDP-dipalmitin + myo-inositol
?
-
-
-
-
?
CDP-dipalmitoyl-sn-glycerol + myo-inositol
CMP + dipalmitoylphosphatidylinositol
CDP-dipalmitoylglyceride + myo-inositol
?
-
-
-
-
?
CDP-dipalmitoylglycerol + D-myo-inositol
CMP + 1,2-dipalmitoyl-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-distearoylglycerol + myo-inositol
CMP + distearoylphosphatidylinositol
-
38% of the activity with CDP-1-stearoyl-2-oleoylglycerol
-
-
r
CDPdipalmitoyl-sn-glycerol + myo-inositol
CMP + dipalmitoylphosphatidylinositol
-
70% of the activity with CDP-1-stearoyl-2-oleoylglycerol
-
-
r
additional information
?
-
2-deoxy-CDP-diacylglycerol + myo-inositol
CMP + ?
-
maximal activity only 36% of the optimal activity reached with CDP-diacylglycerol
-
-
r
2-deoxy-CDP-diacylglycerol + myo-inositol
CMP + ?
-
-
-
-
r
2-deoxy-CDP-diacylglycerol + myo-inositol
CMP + ?
-
optimal activity is 25% higher then with CDP-diacylglycerol
-
-
r
CDP-diacylglycerol + allo-inositol
CMP + phosphatidyl-allo-inositol
-
83% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + allo-inositol
CMP + phosphatidyl-allo-inositol
-
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + allo-inositol
CMP + phosphatidyl-allo-inositol
-
83% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + allo-inositol
CMP + phosphatidyl-allo-inositol
-
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + D-myo-inositol
CMP + phosphatidyl-1D-myo-inositol
key step in lipid biosynthesis
-
-
?
CDP-diacylglycerol + D-myo-inositol
CMP + phosphatidyl-1D-myo-inositol
D-myo-inositol substrates: phosphatidylethanolamine, phosphatidic acid, overexpressed enzyme in bacterial membrane pellets, 30 min, 22°C, pH 8, 1% (v/v) Triton X-100, 20 mM MgCl2
fatty acid analysis by thin-layer chromatography
-
?
CDP-diacylglycerol + epi-inositol
CMP + phosphatidyl-epi-inositol
-
62% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + epi-inositol
CMP + phosphatidyl-epi-inositol
-
conversion of 31.1% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + muco-inositol
CMP + phosphatidyl-muco-inositol
-
41% of the activity on myo-inositol
-
-
?
CDP-diacylglycerol + muco-inositol
CMP + phosphatidyl-muco-inositol
-
conversion of 15.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
specificity of PI synthase for the substrates, no activity with 1L-myo-inositol 1-phosphate
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
specificity of PI synthase for the substrates, no activity with 1L-myo-inositol 1-phosphate
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme plays a role in resynthesis of phosphatidylinositol during agonist-stimulated inositol-phospholipid metabolism
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
membrane lipid biosynthesis
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
key enzyme in cell membrane biosynthesis
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
formation of membrane phospholipids essential for the growth
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
phosphatidylinositol synthase activity increased when zinc is depleted from the growth medium. Analysis of a zrt1DELTA zrt2DELTA mutant defective in plasma membrane zinc transport indicates that the cytoplasmic levels of zinc are responsible for the regulation of phosphatidylinositol synthase. Regulation of PIS1 gene expression by zinc depletion is mediated by the zinc-regulated transcription factor Zap1p. Direct in-teraction between glutathione S-transferase (GST)-Zap1p 687880 and a putative upstream activating sequence (UAS) zinc-responsive element in the PIS1
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
high specificityfor myo-inositol
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-myo-inositol
parasite membrane extracts, infected red blood cells
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-myo-inositol
-
myo-inositol and scyllo-inositol are preferred substrates
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-myo-inositol
-
conversion of 37.4% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, standard reaction: 20 min, 30°C, pH 8, 2 mM MgCl2, 2 mM MnCl2, 1.6 mM Triton X-100
analyses by liquid scintillation counting and thin-layer chromatography
-
?
CDP-diacylglycerol + scyllo-inositol
CMP + phosphatidyl-scyllo-inositol
-
myo-inositol and scyllo-inositol are preferred substrates
-
-
?
CDP-diacylglycerol + scyllo-inositol
CMP + phosphatidyl-scyllo-inositol
-
conversion of 33.7% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
-
-
?
CDP-dilinoleoylglycerol + D-myo-inositol
CMP + 1,2-dilinoleoyl-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-dilinoleoylglycerol + D-myo-inositol
CMP + 1,2-dilinoleoyl-phosphatidyl-1D-myo-inositol
highest activity, preferred in competition assay additionally containing 1,2-dipalmitoyl-, 1,2-dioleoyl-, and 1,2-diheptadecanoyl-CDP-diacylglycerol
-
-
?
CDP-dioleoylglycerol + D-myo-inositol
CMP + 1,2-dioleoyl-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-dioleoylglycerol + D-myo-inositol
CMP + 1,2-dioleoyl-phosphatidyl-1D-myo-inositol
highest activity, preferred in competition assay additionally containing 1,2-dipalmitoyl-, 1,2-dilinoleoyl-, and 1,2-diheptadecanoyl-CDP-diacylglycerol
-
-
?
CDP-dioleoylglycerol + myo-inositol
CMP + dioleoylphosphatidylinositol
-
-
-
r
CDP-dioleoylglycerol + myo-inositol
CMP + dioleoylphosphatidylinositol
-
-
-
r
CDP-dipalmitoyl-sn-glycerol + myo-inositol
CMP + dipalmitoylphosphatidylinositol
-
-
-
-
r
CDP-dipalmitoyl-sn-glycerol + myo-inositol
CMP + dipalmitoylphosphatidylinositol
-
-
-
-
?
additional information
?
-
-
enzyme also catalyzes diacylglycerol-independent exchange reaction between phosphatidylinositol and inositol
-
-
?
additional information
?
-
highly efficient conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic, acid linoleic acid and linolenic acid, complete conversion of CDP-diacylglycerol residues containing palmitic, acid linoleic acid and linolenic acid
-
-
?
additional information
?
-
highly efficient conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic, acid linoleic acid and linolenic acid, complete conversion of CDP-diacylglycerol residues containing palmitic, acid linoleic acid and linolenic acid
-
-
?
additional information
?
-
-
highly efficient conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic, acid linoleic acid and linolenic acid, complete conversion of CDP-diacylglycerol residues containing palmitic, acid linoleic acid and linolenic acid
-
-
?
additional information
?
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, and polyphosphoinositide (PtdIns(4,5)P, PtdIns(4,5)P2) that are enriched in polyunsaturated fatty acids compared to wild-type plants
-
-
?
additional information
?
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, and polyphosphoinositide (PtdIns(4,5)P, PtdIns(4,5)P2) that are enriched in polyunsaturated fatty acids compared to wild-type plants
-
-
?
additional information
?
-
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, and polyphosphoinositide (PtdIns(4,5)P, PtdIns(4,5)P2) that are enriched in polyunsaturated fatty acids compared to wild-type plants
-
-
?
additional information
?
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, phosphatidylethanolamine and diacylglycerol containing less polyunsaturated fatty acids but more saturated and monounsaturated fatty acids, no change in fatty acid composition of polyphopshoinositides compared to wild-type plants
-
-
?
additional information
?
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, phosphatidylethanolamine and diacylglycerol containing less polyunsaturated fatty acids but more saturated and monounsaturated fatty acids, no change in fatty acid composition of polyphopshoinositides compared to wild-type plants
-
-
?
additional information
?
-
-
in transgenic plants, elevated formation of phosphatidic acid, phosphatidylinositol, phosphatidylethanolamine and diacylglycerol containing less polyunsaturated fatty acids but more saturated and monounsaturated fatty acids, no change in fatty acid composition of polyphopshoinositides compared to wild-type plants
-
-
?
additional information
?
-
moderate conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic acid and little linoleic acid, non-converted CDP-diacylglycerol residues containing linoleic acid and linolenic acid
-
-
?
additional information
?
-
moderate conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic acid and little linoleic acid, non-converted CDP-diacylglycerol residues containing linoleic acid and linolenic acid
-
-
?
additional information
?
-
-
moderate conversion of biological mixture of CDP-diacylglycerol substrates (synthesised from phosphatidylethanolamine in plant leaves) into phosphatidyl-1D-myo-inositol mainly containing palmitic acid and little linoleic acid, non-converted CDP-diacylglycerol residues containing linoleic acid and linolenic acid
-
-
?
additional information
?
-
preference of C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
preference of C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
-
preference of C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
preference of polyansaturated C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
preference of polyansaturated C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
-
preference of polyansaturated C18-fatty acid CDP-diacylglycerol substrates
-
-
?
additional information
?
-
-
enzyme also catalyzes diacylglycerol-independent exchange reaction between phosphatidylinositol and inositol
-
-
?
additional information
?
-
-
UDP-diacylglycerol, ADP-diacylglycerol, and GDP-diacylglycerol are inactive as substrates
-
-
?
additional information
?
-
-
CDP, CTP, UMP, AMP, and GMP, are no substrates
-
-
?
additional information
?
-
partial complementation of PIS activity by overexpression of PfPIS/ScPIS hybrids in ScPIS1-deficient Saccharomyces cerevisiae mutant strain BY4743, analysis by enzyme assay (30°C, yeast membrane pellet, in presence of 18 mM octyl-beta-D-glucopyranoside) or lipid incorporation and extraction
-
-
?
additional information
?
-
partial complementation of PIS activity by overexpression of PfPIS/ScPIS hybrids in ScPIS1-deficient Saccharomyces cerevisiae mutant strain BY4743, analysis by enzyme assay (30°C, yeast membrane pellet, in presence of 18 mM octyl-beta-D-glucopyranoside) or lipid incorporation and extraction
-
-
?
additional information
?
-
-
partial complementation of PIS activity by overexpression of PfPIS/ScPIS hybrids in ScPIS1-deficient Saccharomyces cerevisiae mutant strain BY4743, analysis by enzyme assay (30°C, yeast membrane pellet, in presence of 18 mM octyl-beta-D-glucopyranoside) or lipid incorporation and extraction
-
-
?
additional information
?
-
-
enzyme also catalyzes diacylglycerol-independent exchange reaction between phosphatidylinositol and inositol
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
enzyme also catalyzes diacylglycerol-independent exchange reaction between phosphatidylinositol and inositol
-
-
?
additional information
?
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
additional information
?
-
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
additional information
?
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
additional information
?
-
-
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
-
-
?
additional information
?
-
-
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
-
-
?
additional information
?
-
-
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
-
-
?
additional information
?
-
-
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
-
-
?
additional information
?
-
-
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
-
-
?
additional information
?
-
-
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CDP-diacylglycerol + D-myo-inositol
CMP + phosphatidyl-1D-myo-inositol
key step in lipid biosynthesis
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
additional information
?
-
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + 1-phosphatidyl-1D-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme plays a role in resynthesis of phosphatidylinositol during agonist-stimulated inositol-phospholipid metabolism
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
membrane lipid biosynthesis
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
key enzyme in cell membrane biosynthesis
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
formation of membrane phospholipids essential for the growth
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
phosphatidylinositol synthase activity increased when zinc is depleted from the growth medium. Analysis of a zrt1DELTA zrt2DELTA mutant defective in plasma membrane zinc transport indicates that the cytoplasmic levels of zinc are responsible for the regulation of phosphatidylinositol synthase. Regulation of PIS1 gene expression by zinc depletion is mediated by the zinc-regulated transcription factor Zap1p. Direct in-teraction between glutathione S-transferase (GST)-Zap1p 687880 and a putative upstream activating sequence (UAS) zinc-responsive element in the PIS1
-
-
?
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
-
r
CDP-diacylglycerol + myo-inositol
CMP + phosphatidyl-1D-myo-inositol
-
enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol
-
r
additional information
?
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
additional information
?
-
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
additional information
?
-
cytosolically made inositol and CDP-diacylglycerol can access the active site of the yeast PI synthase Pis1 from the cytosolic side
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Murthy, P.P.N.; Agranoff, B.W.
Stereospecific synthesis and enzyme studies of CDP-diacylglycerols
Biochim. Biophys. Acta
712
473-483
1982
Cavia porcellus
brenda
Lykidis, A.; Jackson, P.; Rock, C.O.; Jackowski, S.
The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content
J. Biol. Chem.
272
33402-33409
1997
Homo sapiens (O14735), Homo sapiens
brenda
Prottey, C.; Hawthorne, J.N.
The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas
Biochem. J.
105
379-392
1967
Cavia porcellus
brenda
Rao, R.H.; Strickland, K.P.
On the solubility, stability and partial purification of CDPdiacyl-sn-glycerol: inositol transferase from rat brain
Biochim. Biophys. Acta
348
306-314
1974
Rattus norvegicus
brenda
Hokin-Neaverson, M.; Sadeghian, K.; Harris, D.W.; Merrin, J.S.
Synthesis of CDP-diglyceride from phosphatidylinositol and CMP
Biochem. Biophys. Res. Commun.
78
364-371
1977
Mus musculus
brenda
Takenawa, T.; Egawa, K.
CDP-diglyceride:inositol transferase from rat liver. Purification and properties
J. Biol. Chem.
252
5419-5423
1977
Rattus norvegicus
brenda
Wootton, J.A.; Kinsella, J.E.
Properties of cytidinediphosphodiacyl-sn-glycerol:myoinositol transferase of bovine mammary tissue
Int. J. Biochem.
8
449-456
1977
Bos taurus
-
brenda
Sexton, J.S.; Moore, T.S.
Phosphatidylinositol synthesis in castor bean endosperm
Plant Physiol.
62
978-980
1978
Ricinus communis
brenda
Bleasdale, J.E.; Wallis, P.; MacDonald, P.C.; Johnston, J.M.
Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue
Biochim. Biophys. Acta
575
135-147
1979
Oryctolagus cuniculus
brenda
Robinson, M.L.; Carman, G.M.
Solubilization of microsomal-associated phosphatidylinositol synthase from germinating soybeans
Plant Physiol.
69
146-149
1982
Glycine max
brenda
Fischl, A.S.; Carman, G.M.
Phosphatidylinositol biosynthesis in Saccharomyces cerevisiae: purification and properties of microsome-associated phosphatidylinositol synthase
J. Bacteriol.
154
304-311
1983
Saccharomyces cerevisiae
brenda
Parries, G.S.; Hokin-Neaverson, M.
Phosphatidylinositol synthase from canine pancreas: solubilization by n-octyl glucopyranoside and stabilization by manganese
Biochemistry
23
4785-4791
1984
Canis lupus familiaris
brenda
Parries, G.S.; Hokin-Neaverson, M.
Inhibition of phosphatidylinositol synthase and other membrane-associated enzymes by stereoisomers of hexachlorocyclohexane
J. Biol. Chem.
260
2687-2693
1985
Canis lupus familiaris
brenda
Fischl, A.S.; Homann, M.J.; Poole, M.A.; Carman, G.M.
Phosphatidylinositol synthase from Saccharomyces cerevisiae. Reconstitution, characterization, and regulation of activity
J. Biol. Chem.
261
3178-3183
1986
Saccharomyces cerevisiae
brenda
Kasinathan, C.; Kirchberger, M.A.
Presence of a Ca2+-sensitive CDPdiglyceride-inositol transferase in canine cardiac sarcoplasmic reticulum
Biochemistry
27
2834-2839
1988
Canis lupus familiaris
brenda
Cubitt, A.B.; Gershengorn, M.C.
Characterization of a salt-extractable phosphatidylinositol synthase from rat pituitary-tumour membranes
Biochem. J.
257
639-644
1989
Rattus norvegicus
brenda
Carman, G.M.; Fischl, A.S.
Phosphatidylinositol synthase from yeast
Methods Enzymol.
209
305-312
1992
Saccharomyces cerevisiae
brenda
Imoto, M.; Taniguchi, Y.; Umezawa, K.
Inhibition of CDP-DG: inositol transferase by inostamycin
J. Biochem.
112
299-302
1992
Homo sapiens
brenda
Klezovitch, O.; Brandenburger, Y.; Geindre, M.; Deshusses, J.
Characterization of reactions catalysed by yeast phosphatidylinositol synthase
FEBS Lett.
320
256-260
1993
Saccharomyces cerevisiae
brenda
Antonsson, B.E.
Purification and characterization of phosphatidylinositol synthase from human placenta
Biochem. J.
297
517-522
1994
Homo sapiens
-
brenda
Elabbadi, N.; Ancelin, M.L.; Vial, H.J.
Characterization of phosphatidylinositol synthase and evidence of a polyphosphoinositide cycle in Plasmodium-infected erythrocytes
Mol. Biochem. Parasitol.
63
179-192
1994
Plasmodium knowlesi
brenda
Monaco, M.E.; Feldman, M.; Kleinberg, D.L.
Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein
Biochem. J.
304
301-305
1994
Rattus norvegicus
-
brenda
Justin, A.M.; Hmyene, A.; Kader, J.C.; Mazliak, P.
Compared selectivities of the phosphatidylinositol-synthase from maize coleoptiles either in microsomal membranes or after solubilization
Biochim. Biophys. Acta
1255
161-166
1995
Zea mays
brenda
Antonsson, B.E.; Klig, L.S.
Candida albicans phosphatidylinositol synthase has common features with both Saccharomyces cerevisiae and mammalian phosphatidylinositol synthases
Yeast
12
449-456
1996
Candida albicans
brenda
Antonsson, B.
Phosphatidylinositol synthase from mammalian tissues
Biochim. Biophys. Acta
1348
179-186
1997
Bos taurus, Saccharomyces cerevisiae, Cavia porcellus, Gallus gallus, Oryctolagus cuniculus, Homo sapiens, Meleagris gallopavo, Rattus norvegicus
brenda
Nikawa, J.; Yamashita, S.
Phosphatidylinositol synthase from yeast
Biochim. Biophys. Acta
1348
173-178
1997
Saccharomyces cerevisiae, no activity in Escherichia coli, Rattus norvegicus
brenda
Seron, K.; Dzierszinski, F.; Tomavo, S.
Molecular cloning, functional complementation in Saccharomyces cerevisiae and enzymatic properties of phosphatidylinositol synthase from the protozoan parasite Toxoplasma gondii
Eur. J. Biochem.
267
6571-6579
2000
Toxoplasma gondii, Toxoplasma gondii (Q9XY91), Toxoplasma gondii 76K, Toxoplasma gondii 76K (Q9XY91)
brenda
Xue, H.W.; Hosaka, K.; Plesch, G.; Mueller-Roeber, B.
Cloning of Arabidopsis thaliana phosphatidylinositol synthase and functional expression in the yeast pis mutant
Plant Mol. Biol.
42
757-764
2000
Arabidopsis thaliana, Arabidopsis thaliana (Q8GUK6), no activity in Saccharomyces cerevisiae
brenda
Deguchi, A.; Segawa, K.; Hosaka, K.; Weinstein, I.B.; Umezawa, K.
Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cells
Jpn. J. Cancer Res.
93
157-166
2002
Mus musculus, Rattus norvegicus
brenda
Justin, A.M.; Kader, J.C.; Collin, S.
Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis
Eur. J. Biochem.
269
2347-2352
2002
Arabidopsis thaliana, no activity in Escherichia coli
brenda
Norman, R.A.; McAlister, M.S.; Murray-Rust, J.; Movahedzadeh, F.; Stoker, N.G.; McDonald, N.Q.
Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis
Structure
10
393-402
2002
Mycobacterium tuberculosis
brenda
Blouin, A.; Lavezzi, T.; Moore, T.S.
Membrane lipid biosynthesis in Chlamydomonas reinhardtii. Partial characterization of CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
Plant Physiol. Biochem.
41
11-16
2003
Chlamydomonas reinhardtii
-
brenda
Justin, A.M.; Kader, J.C.; Collin, S.
Synthetic capacity of Arabidopsis phosphatidylinositol synthase 1 expressed in Escherichia coli
Biochim. Biophys. Acta
1634
52-60
2003
Arabidopsis thaliana
brenda
Han, S.H.; Han, G.S.; Iwanyshyn, W.M.; Carman, G.M.
Regulation of the PIS1-encoded phosphatidylinositol synthase in Saccharomyces cerevisiae by zinc
J. Biol. Chem.
280
29017-29024
2005
Saccharomyces cerevisiae
brenda
Das, S.; Hussain, A.; Bock, C.; Keller, W.A.; Georges, F.
Cloning of Brassica napus phospholipase C2 (BnPLC2), phosphatidylinositol 3-kinase (BnVPS34) and phosphatidylinositol synthase1 (BnPtdIns S1) - comparative analysis of the effect of abiotic stresses on the expression of phosphatidylinositol signal transduction-related genes in B. napus
Planta
220
777-784
2005
Brassica napus (Q8H1S8), Brassica napus
brenda
Martin, K.L.; Smith, T.K.
Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei
Biochem. J.
396
287-295
2006
Trypanosoma brucei (Q6KBS8)
brenda
Riggs, B.M.; Lansley, T.A.; Ryals, P.E.
Phosphatidylinositol synthase of Tetrahymena: inositol isomers as substrates in phosphatidylinositol biosynthesis and headgroup exchange reactions
J. Eukaryot. Microbiol.
54
119-124
2007
Tetrahymena vorax, Tetrahymena vorax V2S
brenda
Wengelnik, K.; Vial, H.J.
Characterisation of the phosphatidylinositol synthase gene of Plasmodium species
Res. Microbiol.
158
51-59
2007
Plasmodium falciparum (C0H5B7), Plasmodium falciparum (Q2MJB9), Plasmodium falciparum, Plasmodium knowlesi (Q2MJB8), Plasmodium knowlesi
brenda
Loefke, C.; Ischebeck, T.; Koenig, S.; Freitag, S.; Heilmann, I.
Alternative metabolic fates of phosphatidylinositol produced by phosphatidylinositol synthase isoforms in Arabidopsis thaliana
Biochem. J.
413
115-124
2008
Arabidopsis thaliana (Q8GUK6), Arabidopsis thaliana (Q8LBA6), Arabidopsis thaliana
brenda
Murphy, T.R.; Vihtelic, T.S.; Ile, K.E.; Watson, C.T.; Willer, G.B.; Gregg, R.G.; Bankaitis, V.A.; Hyde, D.R.
Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye
Exp. Eye Res.
93
460-474
2011
Danio rerio
brenda
Davy de Virville, J.; Brown, S.; Cochet, F.; Soler, M.N.; Hoffelt, M.; Ruelland, E.; Zachowski, A.; Collin, S.
Assessment of mitochondria as a compartment for phosphatidylinositol synthesis in Solanum tuberosum
Plant Physiol. Biochem.
48
952-960
2010
Solanum tuberosum
brenda
Zhai, S.M.; Gao, Q.; Xue, H.W.; Sui, Z.H.; Yue, G.D.; Yang, A.F.; Zhang, J.R.
Overexpression of the phosphatidylinositol synthase gene from Zea mays in tobacco plants alters the membrane lipids composition and improves drought stress tolerance
Planta
235
69-84
2012
Zea mays
brenda
Morii, H.; Ogawa, M.; Fukuda, K.; Taniguchi, H.
Ubiquitous distribution of phosphatidylinositol phosphate synthase and archaetidylinositol phosphate synthase in bacteria and archaea, which contain inositol phospholipid
Biochem. Biophys. Res. Commun.
443
86-90
2013
Homo sapiens, Saccharomyces cerevisiae (P70500), Saccharomyces cerevisiae
brenda
Bochud, A.; Conzelmann, A.
The active site of yeast phosphatidylinositol synthase Pis1 is facing the cytosol
Biochim. Biophys. Acta
1851
629-640
2015
Saccharomyces cerevisiae (P06197), Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4742 (P06197)
brenda
Liu, X.; Zhai, S.; Zhao, Y.; Sun, B.; Liu, C.; Yang, A.; Zhang, J.
Overexpression of the phosphatidylinositol synthase gene (ZmPIS) conferring drought stress tolerance by altering membrane lipid composition and increasing ABA synthesis in maize
Plant Cell Environ.
36
1037-1055
2013
Zea mays (Q6UG58), Zea mays, Zea mays DH4866 (Q6UG58)
brenda
Long, Q.; Yue, F.; Liu, R.; Song, S.; Li, X.; Ding, B.; Yan, X.; Pei, Y.
The phosphatidylinositol synthase gene (GhPIS) contributes to longer, stronger, and finer fibers in cotton
Mol. Genet. Genomics
293
1139-1149
2018
Gossypium hirsutum (A0A075T0L0), Gossypium hirsutum
brenda