Reference on EC 2.7.7.52 - RNA uridylyltransferase
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Bakalara, N.; Simpson, A.M.; Simpson, L.
The Leishmania kinetoplast-mitochondrion contains terminal uridylyltransferase and RNA ligase activities
J. Biol. Chem.
264
18679-18686
1989
Leishmania tarentolae, Leishmania tarentolae UC
Zabel, P.; Dorssers, L.; Wernars, K.; van Kammen, A.
Terminal uridylyl transferase of Vigna unguiculata: purification and characterization of an enzyme catalyzing the addition of a single UMP residue to the 3-end of an RNA primer
Nucleic Acids Res.
9
2433-2453
1981
Vigna unguiculata
Andrews, N.C.; Baltimore, D.
Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction
Proc. Natl. Acad. Sci. USA
83
221-225
1986
Homo sapiens
Sugisaki, H.
Purification of terminal uridylyltransferase from the Crithidia kinetoplast-mitochondrion
ICR Annual Report
7
58-59
2001
Crithidia fasciculata
-
Aphasizhev, R.; Sbicego, S.; Peris, M.; Jang, S.H.; Aphasizheva, I.; Simpson, A.M.; Rivlin, A.; Simpson, L.
Trypanosome mitochondrial 3' terminal uridylyl transferase (TUTase): the key enzyme in U-insertion/deletion RNA editing
Cell
108
637-648
2002
Leishmania tarentolae, Trypanosoma brucei
Ernst, N.L.; Panicucci, B.; Igo, R.P., Jr.; Panigrahi, A.K.; Salavati, R.; Stuart, K.
TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome
Mol. Cell
11
1525-1536
2003
Trypanosoma brucei
Trippe, R.; Richly, H.; Benecke, B.J.
Biochemical characterization of a U6 small nuclear RNA-specific terminal uridylyltransferase
Eur. J. Biochem.
270
971-980
2003
Homo sapiens
Aphasizhev, R.; Aphasizheva, I.; Simpson, L.
A tale of two TUTases
Proc. Natl. Acad. Sci. USA
100
10617-10622
2003
Trypanosoma brucei
Gott, J.M.
Two distinct roles for terminal uridylyl transferases in RNA editing
Proc. Natl. Acad. Sci. USA
100
10583-10584
2003
Trypanosoma brucei
Aphasizhev, R.; Aphasizheva, I.; Simpson, L.
Multiple terminal uridylyltransferases of trypanosomes
FEBS Lett.
572
15-18
2004
Trypanosoma brucei
Nebohacova, M.; Maslov, D.A.; Falick, A.M.; Simpson, L.
The effect of RNA interference down-regulation of RNA editing 3'-terminal uridylyl transferase (TUTase) 1 on mitochondrial de novo protein synthesis and stability of respiratory complexes in Trypanosoma brucei
J. Biol. Chem.
279
7819-7825
2004
Trypanosoma brucei
Stagno, J.; Aphasizheva, I.; Rosengarth, A.; Luecke, H.; Aphasizhev, R.
UTP-bound and Apo structures of a minimal RNA uridylyltransferase
J. Mol. Biol.
366
882-899
2007
Trypanosoma brucei (Q381M1)
Aphasizhev, R.; Aphasizheva, I.
RNA editing uridylyltransferases of trypanosomatids
Methods Enzymol.
424
55-73
2007
Leishmania tarentolae, Trypanosoma brucei
Zhelonkina, A.G.; OHearn, S.F.; Law, J.A.; Cruz-Reyes, J.; Huang, C.E.; Alatortsev, V.S.; Sollner-Webb, B.
T. brucei RNA editing: action of the U-insertional TUTase within a U-deletion cycle
RNA
12
476-487
2006
Trypanosoma brucei, Trypanosoma brucei TREU-667
Aphasizhev, R.; Aphasizheva, I.
Terminal RNA uridylyltransferases of trypanosomes
Biochim. Biophys. Acta
1779
270-280
2008
Leishmania tarentolae, Trypanosoma brucei
Heo, I.; Ha, M.; Lim, J.; Yoon, M.; Park, J.; Kwon, S.; Chang, H.; Kim, V.
Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs
Cell
151
521-532
2012
Homo sapiens (Q5TAX3), Homo sapiens (Q5VYS8)
Stagno, J.; Aphasizheva, I.; Bruystens, J.; Luecke, H.; Aphasizhev, R.
Structure of the mitochondrial editosome-like complex associated TUTase 1 reveals divergent mechanisms of UTP selection and domain organization
J. Mol. Biol.
399
464-475
2010
Trypanosoma brucei (C7AJA4), Trypanosoma brucei
Ringpis, G.E.; Aphasizheva, I.; Wang, X.; Huang, L.; Lathrop, R.H.; Hatfield, G.W.; Aphasizhev, R.
Mechanism of U insertion RNA editing in trypanosome mitochondria: the bimodal TUTase activity of the core complex
J. Mol. Biol.
399
680-695
2010
Trypanosoma brucei
Ringpis, G.E.; Stagno, J.; Aphasizhev, R.
Mechanism of U-insertion RNA editing in trypanosome mitochondria: characterization of RET2 functional domains by mutational analysis
J. Mol. Biol.
399
696-706
2010
Trypanosoma brucei
Aphasizheva, I.; Aphasizhev, R.
RET1-catalyzed uridylylation shapes the mitochondrial transcriptome in Trypanosoma brucei
Mol. Cell. Biol.
30
1555-1567
2010
Trypanosoma brucei
Talsky, K.B.; Collins, K.
Strand-asymmetric endogenous Tetrahymena small RNA production requires a previously uncharacterized uridylyltransferase protein partner
RNA
18
1553-1562
2012
Tetrahymena thermophila (I1Y9V9)
Thornton, J.E.; Chang, H.M.; Piskounova, E.; Gregory, R.I.
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7)
RNA
18
1875-1885
2012
Homo sapiens (Q5TAX3), Homo sapiens (Q5VYS8)
Reimao-Pinto, M.M.; Ignatova, V.; Burkard, T.R.; Hung, J.H.; Manzenreither, R.A.; Sowemimo, I.; Herzog, V.A.; Reichholf, B.; Farina-Lopez, S.; Ameres, S.L.
Uridylation of RNA hairpins by tailor confines the emergence of microRNAs in Drosophila
Mol. Cell
59
203-216
2015
Drosophila melanogaster (Q9VI58)
Sement, F.M.; Ferrier, E.; Zuber, H.; Merret, R.; Alioua, M.; Deragon, J.M.; Bousquet-Antonelli, C.; Lange, H.; Gagliardi, D.
Uridylation prevents 3 trimming of oligoadenylated mRNAs
Nucleic Acids Res.
41
7115-7127
2013
Arabidopsis thaliana (O64642), Arabidopsis thaliana Col-0 (O64642)
Tu, B.; Liu, L.; Xu, C.; Zhai, J.; Li, S.; Lopez, M.A.; Zhao, Y.; Yu, Y.; Ramachandran, V.; Ren, G.; Yu, B.; Li, S.; Meyers, B.C.; Mo, B.; Chen, X.
Distinct and cooperative activities of HESO1 and URT1 nucleotidyl transferases in microRNA turnover in Arabidopsis
PLoS Genet.
11
e1005119
2015
Arabidopsis thaliana (O64642), Arabidopsis thaliana (Q5XET5)
Chung, C.Z.; Jo, D.H.; Heinemann, I.U.
Nucleotide specificity of the human terminal nucleotidyltransferase Gld2 (TUT2)
RNA
22
1239-1249
2016
Homo sapiens
Zhu, L.; Hu, Q.; Cheng, L.; Jiang, Y.; Lv, M.; Liu, Y.; Li, F.; Shi, Y.; Gong, Q.
Crystal structure of Arabidopsis terminal uridylyl transferase URT1
Biochem. Biophys. Res. Commun.
524
490-496
2020
Arabidopsis thaliana (O64642)
Yashiro, Y.; Tomita, K.
Function and regulation of human terminal uridylyltransferases
Front. Genet.
9
538
2018
Homo sapiens (F5H0R1), Homo sapiens (Q5TAX3), Homo sapiens (Q5VYS8)
Modepalli, V.; Moran, Y.
Evolution of miRNA tailing by 3' terminal uridylyl transferases in Metazoa
Genome Biol. Evol.
9
1547-1560
2017
Amphimedon queenslandica, Drosophila melanogaster, Hydra vulgaris, Nematostella vectensis
George, J.T.; Azhar, M.; Aich, M.; Sinha, D.; Ambi, U.B.; Maiti, S.; Chakraborty, D.; Srivatsan, S.G.
Terminal uridylyl transferase mediated site-directed access to clickable chromatin employing CRISPR-dCas9
J. Am. Chem. Soc.
142
13954-13965
2020
Schizosaccharomyces pombe
Kim, H.; Kim, J.; Yu, S.; Lee, Y.Y.; Park, J.; Choi, R.J.; Yoon, S.J.; Kang, S.G.; Kim, V.N.
A mechanism for microRNA arm switching regulated by uridylation
Mol. Cell
78
1224-1236
2020
Homo sapiens (Q5TAX3), Homo sapiens (Q5VYS8)
Yamashita, S.; Nagaike, T.; Tomita, K.
Crystal structure of the Lin28-interacting module of human terminal uridylyltransferase that regulates let-7 expression
Nat. Commun.
10
1960
2019
Homo sapiens (Q5TAX3), Homo sapiens
Yamashita, S.; Takagi, Y.; Nagaike, T.; Tomita, K.
Crystal structures of U6 snRNA-specific terminal uridylyltransferase
Nat. Commun.
8
15788
2017
Homo sapiens (F5H0R1), Homo sapiens
Kroupova, A.; Ivascu, A.; Reimao-Pinto, M.M.; Ameres, S.L.; Jinek, M.
Structural basis for acceptor RNA substrate selectivity of the 3 terminal uridylyl transferase Tailor
Nucleic Acids Res.
47
1030-1042
2019
Drosophila melanogaster (Q9VI58)
Chung, C.; Jaramillo, J.; Ellis, M.; Bour, D.; Seidl, L.; Jo, D.; Turk, M.; Mann, M.; Bi, Y.; Haniford, D.; Duennwald, M.; Heinemann, I.
RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe
Nucleic Acids Res.
47
3045-3057
2019
Schizosaccharomyces pombe, Schizosaccharomyces pombe BG 0000H6
Cheng, L.; Li, F.; Jiang, Y.; Yu, H.; Xie, C.; Shi, Y.; Gong, Q.
Structural insights into a unique preference for 3 terminal guanine of mirtron in Drosophila TUTase Tailor
Nucleic Acids Res.
47
495-508
2019
Drosophila melanogaster (Q9VI58)
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