Information on EC 2.7.4.31 - [5-(aminomethyl)furan-3-yl]methyl phosphate kinase

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The expected taxonomic range for this enzyme is: Methanocaldococcus jannaschii

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EC NUMBER
COMMENTARY hide
2.7.4.31
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RECOMMENDED NAME
GeneOntology No.
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [5-(aminomethyl)furan-3-yl]methyl phosphate = ADP + [5-(aminomethyl)furan-3-yl]methyl diphosphate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Methane metabolism
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methanofuran biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
ATP:[5-(aminomethyl)furan-3-yl]methyl-phosphate phosphotransferase
Requires Mg2+. The enzyme, isolated from the archaeon Methanocaldococcus jannaschii, participates in the biosynthesis of the methanofuran cofactor.
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
AMP + ATP
2 ADP
show the reaction diagram
ATP + [5-(aminomethyl)furan-3-yl]methyl phosphate
ADP + [5-(aminomethyl)furan-3-yl]methyl diphosphate
show the reaction diagram
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
MfnE exclusively uses Mg2+ as a cofactor to facilitate phosphoryl group transfer
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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
EDTA
10 mM, complete loss of activity
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.072
substrate AMP, pH 7.0, 80°C
0.16
substrate 5-(aminomethyl)-3-furanmethanol-phosphate, pH 7.0, 80°C
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
24000
x * 24000, SDS-PAGE
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SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
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LINKS TO OTHER DATABASES (specific for EC-Number 2.7.4.31)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
SYSTERS
Protein Mutant Database
InterPro (database of protein families, domains and functional sites)