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Information on EC 2.7.4.24 - diphosphoinositol-pentakisphosphate 1-kinase

for references in articles please use BRENDA:EC2.7.4.24
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EC Tree
IUBMB Comments
This enzyme is activated by osmotic shock . Ins(1,3,4,5,6)P5, 1D-myo-inositol diphosphate tetrakisphosphate and 1D-myo-inositol bisdiphosphate triphosphate are not substrates . The enzyme specifically phosphorylates the 1-position of the substrates .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Archaea
Synonyms
ppip5k, diphosphoinositol pentakisphosphate kinase, ip7 kinase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate = ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
show the reaction diagram
(1)
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ATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate
show the reaction diagram
(2)
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PATHWAY SOURCE
PATHWAYS
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