Information on EC 2.7.3.10 - agmatine kinase

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The expected taxonomic range for this enzyme is: Ochromonas danica

EC NUMBER
COMMENTARY hide
2.7.3.10
-
RECOMMENDED NAME
GeneOntology No.
agmatine kinase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + agmatine = ADP + N4-phosphoagmatine
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phospho group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
ATP:agmatine N4-phosphotransferase
L-Arginine can act as acceptor, but more slowly.
CAS REGISTRY NUMBER
COMMENTARY hide
71061-39-7
-
9076-75-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + agmatine
ADP + N4-phosphoagmatine
show the reaction diagram
-
-
-
-
?
ATP + L-Arg
ADP + N5-phosphoarginine
show the reaction diagram
-
18% of the activity with agamatine
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
-
no activity without divalent cation, Ca2+ is more effective than Mg2+
Mg2+
-
no activity without divalent cation, less effective than Ca2+
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.5
-
2 optima in the reaction with agmatine in presence of Ca2+: pH 7.5 and pH 9.0. Reaction with L-Arg occurs only at pH 7.5-8.0, activity at pH 7.5 is higher than at pH 8.0
9
-
2 optima in the reaction with agmatine in presence of Ca2+: pH 7.5 and pH 9.0
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.5 - 8
-
reaction with L-Arg occurs only at pH 7.5-8.0, no activity at pH 7.0 and 8.6
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
80000
-
gel filtration