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Disease on EC 2.7.2.3 - phosphoglycerate kinase

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DISEASE
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5'-nucleotidase deficiency
Enzymatic diagnosis in non-spherocytic hemolytic anemia.
6-phosphofructokinase deficiency
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
ACTH-Secreting Pituitary Adenoma
Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease.
Acute Kidney Injury
Familial phosphoglycerate kinase deficiency associated with rhabdomyolysis and acute renal failure: abnormality in mRNA splicing?
Adenocarcinoma
Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma.
Protein profiles associated with survival in lung adenocarcinoma.
Adenocarcinoma of Lung
Protein profiles associated with survival in lung adenocarcinoma.
Adenoma
Clonal analysis of parathyroid adenomas by means of the polymerase chain reaction.
Lentiviral vectors efficiently transduce human gonadotroph and somatotroph adenomas in vitro. Targeted expression of transgene by pituitary hormone promoters.
The role of hyperplasia in multiple parathyroid adenomas.
adenylate kinase deficiency
Enzymatic diagnosis in non-spherocytic hemolytic anemia.
Red cell enzymopathies as a model of inborn errors of metabolism.
alpha-Thalassemia
A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe.
Alzheimer Disease
Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease.
Anemia
Clonal hematopoiesis in patients with acquired aplastic anemia.
Long-term and stable correction of uremic anemia by intramuscular injection of plasmids containing hypoxia-regulated system of Epo expression.
Phosphoglycerate kinase deficiency due to a novel mutation (c. 1180A>G) manifesting as chronic hemolytic anemia in a Japanese boy.
Red cell phosphoglycerate kinase deficiency. A new cause of non-spherocytic hemolytic anemia.
Anemia, Aplastic
Clonal haematopoiesis in children with acquired aplastic anaemia.
Clonal hematopoiesis as defined by polymorphic X-linked loci occurs infrequently in aplastic anemia.
Anemia, Hemolytic
A new case of phosphoglycerate kinase deficiency: PGK Creteil associated with rhabdomyolysis and lacking hemolytic anemia.
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: Molecular and functional characterization.
A novel missense mutation (1060G --> C) in the phosphoglycerate kinase gene in a Japanese boy with chronic haemolytic anaemia, developmental delay and rhabdomyolysis.
A Novel Missense Variant Associated with A Splicing Defect in A Myopathic Form of PGK1 Deficiency in The Spanish Population.
A phosphoglycerate kinase mutant (PGK Herlev; D285V) in a Danish patient with isolated chronic hemolytic anemia: mechanism of mutation and structure-function relationships.
A phosphoglycerate kinase variant, PGK Uppsala, associated with hemolytic anemia.
Altered expression of PGK1 in a family with phosphoglycerate kinase deficiency.
Characterization of a phosphoglycerate kinase deficiency variants not associated with hemolytic anemia.
Characterization of a phosphoglycerate kinase variant associated with hemolytic anemia.
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?
Enzymatic and metabolic characterization of the phosphoglycerate kinase deficiency associated with chronic hemolytic anemia caused by the PGK-Barcelona mutation.
Erythrocyte phosphoglycerate kinase deficiency: enzymatic and oxygen binding studies.
Hereditary deficiency of phosphoglycerate kinase: a new variant in erythrocytes and leucocytes, not associated with haemolytic anaemia.
Human erythrocyte phosphoglycerate kinase deficiency: presence in a deficient patient of a stable variant with lowered catalytic activity.
Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Créteil and PGK Amiens.
Mitochondrial changes in muscle phosphoglycerate kinase deficiency.
Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia.
Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3.
Molecular defect of a phosphoglycerate kinase variant associated with haemolytic anaemia and neurological disorders in a large kindred.
Molecular genetic heterogeneity of phosphoglycerate kinase (PGK) deficiency.
Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line.
Normal mRNA content in a phosphoglycerate kinase variant with severe enzyme deficiency.
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
Parkinsonism in PGK1 deficiency implicates the glycolytic pathway in nigrostriatal dysfunction.
PGK deficiency.
Phosphoglycerate kinase (PKG) deficiency hereditary nonspherocytic hemolytic anemia: report of a case found in a Japanese family.
Phosphoglycerate kinase abnormalities: functional, structural and genomic aspects.
Phosphoglycerate kinase deficiency due to a novel mutation (c. 1180A>G) manifesting as chronic hemolytic anemia in a Japanese boy.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphoglycerate kinase deficiency myopathy: biochemical and immunological studies of the mutant enzyme.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
Red cell phosphoglycerate kinase deficiency. A new cause of non-spherocytic hemolytic anemia.
Slowly progressive leukodystrophy in an adolescent male with phosphoglycerate kinase deficiency.
Structural and functional properties of mutant Arg203Pro from yeast phosphoglycerate kinase, as a model of phosphoglycerate kinase-Uppsala.
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Therapeutic Benefit of Blood Transfusion in a Patient With Novel PGK1 Mutation (c.461T>C [p.L154P]).
Tissue levels of glycolytic enzymes in phosphoglycerate kinase deficiency.
Two new phosphoglycerate kinase mutations associated with chronic haemolytic anaemia and neurological dysfunction in two patients from Spain.
Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia.
Anemia, Hemolytic, Congenital
Hereditary hemolytic anemia associated with phosphoglycerate kinase deficiency in erythrocytes and leukocytes. A probable X-chromosome-linked syndrome.
Hereditary hemolytic anemia: association with phosphoglycerate kinase deficiency in erythrocytes and leukocytes.
Molecular aspects of erythroenzymopathies associated with hereditary hemolytic anemia.
[Congenital hemolytic anemia associated with phosphoglycerate kinase deficiency in erythrocytes, polynuclear cells and lymphocytes]
Anemia, Hemolytic, Congenital Nonspherocytic
Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3.
Normal mRNA content in a phosphoglycerate kinase variant with severe enzyme deficiency.
Anemia, Sideroblastic
Linkage analysis of a large pedigree with hereditary sideroblastic anaemia.
Sideroblastic anaemia.
X-linked sideroblastic anemia and ataxia: linkage to phosphoglycerate kinase at Xq13.
Anencephaly
A human autosomal phosphoglycerate kinase locus maps near the HLA cluster.
Arthritis
Overexpression of CXC chemokine ligand 14 exacerbates collagen-induced arthritis.
Asthenozoospermia
Characteristics of testis-specific phosphoglycerate kinase 2 and its association with human sperm quality.
Astrocytoma
Over-expression of cofilin-1 and phosphoglycerate kinase 1 in astrocytomas involved in pathogenesis of radioresistance.
Phosphoglycerate kinase 1 promotes radioresistance in U251 human glioma cells.
Ataxia
Sideroblastic anaemia.
X-linked sideroblastic anemia and ataxia: linkage to phosphoglycerate kinase at Xq13.
Bacteremia
Comparative Exoproteomics and Host Inflammatory Response in Staphylococcus aureus Skin and Soft Tissue Infections, Bacteremia, and Subclinical Colonization.
Bone Diseases, Metabolic
A proteomic study of protein variation between osteopenic and age-matched control bone tissue.
Bone Resorption
Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice.
Brain Neoplasms
[Enzymes in cerebrospinal fluid (HK, TIM, GAPDH, PGK, enolase, PK, LDH, GPT, ChE) in normal samples, in brain neoplasms and other neurologic diseases]
Breast Neoplasms
Clonal analysis of benign and malignant human breast tumors by means of polymerase chain reaction.
Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysis.
Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer.
Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer.
Candidiasis
Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies.
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
carboxypeptidase t deficiency
Metabolic causes of myoglobinuria.
[Clinical and biochemical analysis of 27 patients with myoglobinuria of unknown causes]
Carcinogenesis
A spring loaded release mechanism regulates domain movement and catalysis in phosphoglycerate kinase.
Conformational dynamics in phosphoglycerate kinase, an open and shut case?
Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing.
Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.
Long noncoding RNA MSC-AS1 promotes hepatocellular carcinoma oncogenesis via inducing the expression of phosphoglycerate kinase 1.
pH-dependent relationship between thermodynamic and kinetic stability in the denaturation of human phosphoglycerate kinase 1.
Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea.
Sequential studies of skin tumorigenesis in PGK mosaic mice: the effect of repeated exposure to a carcinogen on regressed mouse skin papillomas.
Sequential studies of skin tumorigenesis in phosphoglycerate kinase mosaic mice: effect of resumption of promotion on regressed papillomas.
Studies of skin tumorigenesis in PGK mosaic mice: many promoter-independent papillomas and carcinomas do not develop from pre-existing promoter-dependent papillomas.
X-linked allozymes of phosphoglycerate kinase as tools in experimental carcinogenesis in the mouse.
Carcinoma
Clonal origin of skin and bone tumors produced by repeated beta-irradiation in mosaic cell mice.
Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysis.
Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma.
Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.
Lentivirus vectors incorporating the immunoglobulin heavy chain enhancer and matrix attachment regions provide position-independent expression in B lymphocytes.
Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.
Nucleotide-binding domain of phosphoglycerate kinase 1 reduces tumor growth by suppressing COX-2 expression.
Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo.
Purification and characterization of 3-phosphoglycerate kinase from Ehrlich ascites carcinoma cells.
Regulation of urokinase receptor expression by phosphoglycerate kinase is independent of its catalytic activity.
Regulation of urokinase receptor expression by phosphoglycerate kinase.
Short tandem repeat polymorphism linkage to the androgen receptor gene in prostate carcinoma.
Studies of skin tumorigenesis in PGK mosaic mice: many promoter-independent papillomas and carcinomas do not develop from pre-existing promoter-dependent papillomas.
Test of recurrence after experimental radiation therapy of chemically induced autochthonous tumors in mosaic mice.
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
Carcinoma, Adenosquamous
Colliding primary lung cancers of adenosquamous carcinoma and large cell neuroendocrine carcinoma.
Carcinoma, Ehrlich Tumor
Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system.
Carcinoma, Embryonal
Comparative analysis of retroviral vector expression in mouse embryonal carcinoma cells.
DNA methylation of two X chromosome genes in female somatic and embryonal carcinoma cells.
Enhanced transgene expression in embryonal carcinoma stem cells: transcription through introns and exons increases gene copy numbers and forestalls silencing.
Intragenic regions of the murine Pgk-1 locus enhance integration of transfected DNAs into genomes of embryonal carcinoma cells.
Carcinoma, Hepatocellular
Antrodia cinnamomea Inhibits Migration in Human Hepatocellular Carcinoma Cells: The Role of ERp57 and PGK-1.
Clonality in hepatocellular carcinoma: analysis of methylation pattern of polymorphic X-chromosome-linked phosphoglycerate kinase gene in females.
Development of a gene therapy strategy to target hepatocellular carcinoma based inhibition of protein phosphatase 2A using the ?-fetoprotein promoter enhancer and pgk promoter: an in vitro and in vivo study.
Downregulation of long non-protein coding RNA MVIH impairs glioblastoma cell proliferation and invasion through an miR-302a-dependent mechanism.
Expression of hypoxia-inducible genes in tumor cells.
Gene therapy for hepatocellular carcinoma based on tumour-selective suicide gene expression using the alpha-fetoprotein (AFP) enhancer and a housekeeping gene promoter.
Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha.
Inhibition of Non-flux-Controlling Enzymes Deters Cancer Glycolysis by Accumulation of Regulatory Metabolites of Controlling Steps.
Long noncoding RNA MSC-AS1 promotes hepatocellular carcinoma oncogenesis via inducing the expression of phosphoglycerate kinase 1.
MicroRNA-450b-3p inhibits cell growth by targeting phosphoglycerate kinase 1 in hepatocellular carcinoma.
Subchromosomal localization and order of GLA, PGK1, HPRT, and G6PD loci on the X chromosome of the American mink (Mustela vison).
[Influence of phosphoglycerate kinase 1 on metastasis and invasion of hepatoma cells and prognosis of liver cancer].
[The distribution of 4 genes (alpha GAL, PGK-1, HPRT and G6PD) on the X chromosome of the American mink (Mustela vison)]
Carcinoma, Intraductal, Noninfiltrating
Clonal analysis of predominantly intraductal carcinoma and precancerous lesions of the breast by means of polymerase chain reaction.
Carcinoma, Lewis Lung
Nucleotide-binding domain of phosphoglycerate kinase 1 reduces tumor growth by suppressing COX-2 expression.
Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo.
Carcinoma, Neuroendocrine
Colliding primary lung cancers of adenosquamous carcinoma and large cell neuroendocrine carcinoma.
Carcinoma, Non-Small-Cell Lung
Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma.
Carcinoma, Pancreatic Ductal
Enhanced levels of annexins in pancreatic carcinoma cells of Syrian hamsters and their intrapancreatic allografts.
Carcinoma, Squamous Cell
Clonal origin of skin and bone tumors produced by repeated beta-irradiation in mosaic cell mice.
Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing.
carnitine o-palmitoyltransferase deficiency
Neonatal metabolic myopathies.
Cholesteatoma
Pathogenesis of Middle Ear Cholesteatoma. A New Model of Experimentally Induced Cholesteatoma in Mongolian Gerbils.
Choroideremia
22-Mb integrated physical and genetic map based on YAC/STS content spanning the interval DXS1125-DXS95 in human Xq12-q21.31.
Comparative mapping of canine and human proximal Xq and genetic analysis of canine X-linked severe combined immunodeficiency.
Clonorchiasis
Molecular cloning and immunological characterization of phosphoglycerate kinase from Clonorchis sinensis.
Colonic Neoplasms
Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.
Coronary Artery Disease
Optimisation of methods for quantifying plasma mRNA levels from genes responsible for coronary artery plaque development and destabilization.
Cysts
Analysis of clonality in human endometriotic cysts based on evaluation of X chromosome inactivation in archival formalin-fixed, paraffin-embedded tissue.
Cytochrome-c Oxidase Deficiency
Neonatal metabolic myopathies.
Deafness
The gene for X-linked progressive mixed deafness with perilymphatic gusher during stapes surgery (DFN3) is linked to PGK.
Dehydration
Phosphoglycerate kinase 1 expression responds to freezing, anoxia, and dehydration stresses in the freeze tolerant wood frog, Rana sylvatica.
Diabetes Mellitus
Red cell phosphoglycerate kinase in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Red cell phosphoglycerate kinase in insulin-dependent diabetes mellitus.
Diphtheria
Folding funnels and conformational transitions via hinge-bending motions.
Down Syndrome
Clonal analysis of transient myeloproliferative disorder in Down's syndrome.
Increased phosphoglycerate kinase in the brains of patients with Down's syndrome but not with Alzheimer's disease.
Monoclonal nature of transient abnormal myelopoiesis in Down's syndrome.
Dystonia Musculorum Deformans
22-Mb integrated physical and genetic map based on YAC/STS content spanning the interval DXS1125-DXS95 in human Xq12-q21.31.
Endometrial Neoplasms
[Expression of phosphoglycerate kinase 1 in endometrial carcinoma and its association with patients' outcome].
Endometriosis
Analysis of clonality in human endometriotic cysts based on evaluation of X chromosome inactivation in archival formalin-fixed, paraffin-embedded tissue.
Fabry Disease
X-Linked Parkinsonism: Phenotypic and Genetic Heterogeneity.
Fibroadenoma
Clonal analysis of fibroadenoma and phyllodes tumor of the breast.
Fibrosarcoma
Clonal interaction in tumours.
Effect of solvents on methylcholanthrene-induced carcinogenesis in mice.
Evidence concerning the clonal nature of chemically induced tumors: phosphoglycerate kinase-1 isozyme patterns in chemically induced fibrosarcomas.
Evidence for single-cell origin of 3-methylcholanthrene-induced fibrosarcomas in mice with cellular mosaicism.
Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase.
fructose-bisphosphate aldolase deficiency
Red cell enzymopathies as a model of inborn errors of metabolism.
Tarui disease and distal glycogenoses: clinical and genetic update.
Gallbladder Neoplasms
Down-Regulated Phosphoglycerate Kinase 1 Expression Is Associated With Poor Prognosis in Patients With Gallbladder Cancer.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Genetic Diseases, Inborn
A negative waveform in the scotopic response in a patient with phosphoglycerate kinase deficiency: a visual electrophysiology report.
Structural and energetic basis of protein kinetic destabilization in human phosphoglycerate kinase 1 deficiency.
Glioblastoma
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Glioma
Cofilin-1 and phosphoglycerate kinase 1 as promising indicators for glioma radiosensibility and prognosis.
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52.
Phosphoglycerate kinase 1 promotes radioresistance in U251 human glioma cells.
The Neurogenic Compound P7C3 Regulates the Aerobic Glycolysis by Targeting Phosphoglycerate Kinase 1 in Glioma.
[Experimental study on human glioma SHG44 treated by HSV-tk gene therapy]
Glucose Intolerance
Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability.
glucose-6-phosphate isomerase deficiency
Enzymatic diagnosis in non-spherocytic hemolytic anemia.
glutathione synthase deficiency
Enzymatic diagnosis in non-spherocytic hemolytic anemia.
Glycogen Storage Disease
Metabolic myopathies.
Neonatal metabolic myopathies.
Tarui disease and distal glycogenoses: clinical and genetic update.
Growth Hormone-Secreting Pituitary Adenoma
Lentiviral vectors efficiently transduce human gonadotroph and somatotroph adenomas in vitro. Targeted expression of transgene by pituitary hormone promoters.
Heart Arrest
Selection of reference genes for quantitative real-time PCR in a rat asphyxial cardiac arrest model.
Hematologic Diseases
Clonality in hematopoietic disorders.
[Clonal study of hematopoietic cells]
Hematologic Neoplasms
Clonal determination by the fragile X (FMR1) and phosphoglycerate kinase (PGK) genes in hematological malignancies.
Hepatitis
Human CMV immediate-early enhancer: a useful tool to enhance cell-type-specific expression from lentiviral vectors.
Herpes Simplex
Comparative analysis of retroviral vector expression in mouse embryonal carcinoma cells.
Gene therapy for hepatocellular carcinoma based on tumour-selective suicide gene expression using the alpha-fetoprotein (AFP) enhancer and a housekeeping gene promoter.
Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene.
Histiocytosis
Langerhans'-cell histiocytosis (histiocytosis X)--a clonal proliferative disease.
Hyperparathyroidism
Clonal analysis of nodular parathyroid hyperplasia in renal hyperparathyroidism.
Hyperparathyroidism, Secondary
PDGFB-based stem cell gene therapy increases bone strength in the mouse.
Hypospadias
A hemizygous short tandem repeat polymorphism 3' to the human phosphoglycerate kinase gene.
Short tandem repeat polymorphism linkage to the androgen receptor gene in prostate carcinoma.
Ichthyosis, X-Linked
Dosage of the Sts gene in the mouse.
Incontinentia Pigmenti
X inactivation as a mechanism of selection against lethal alleles: further investigation of incontinentia pigmenti and X linked lymphoproliferative disease.
Infections
A hypothetical model of crossing Bombyx mori nucleopolyhedrovirus through its host midgut physical barrier.
Analysis of the serologic response to systemic Candida albicans infection in a murine model.
Characterization and role of PGK from Litopenaeus vannamei in WSSV infection.
Chloroplast phosphoglycerate kinase is involved in the targeting of Bamboo mosaic virus to chloroplasts in Nicotiana benthamiana plants.
Construction of a lentiviral T/A vector for direct analysis of PCR-amplified promoters.
Efficient transduction of monocyte- and CD34+-derived Langerhans cells with lentiviral vectors in the absence of phenotypic and functional maturation.
Elongation factor 1 (EF1alpha) promoter in a lentiviral backbone improves expression of the CD20 suicide gene in primary T lymphocytes allowing efficient rituximab-mediated lysis.
HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Immune response to Schistosoma mansoni phosphoglycerate kinase during natural and experimental infection: identification of a schistosome-specific B-cell epitope.
Immune responses in rats and sheep induced by a DNA vaccine containing the phosphoglycerate kinase gene of Fasciola hepatica and liver fluke infection.
Linear correlation between average fluorescence intensity of green fluorescent protein and the multiplicity of infection of recombinant adenovirus.
Long-term promoter activity during herpes simplex virus latency.
Lymphocyte responses of rats vaccinated with cDNA encoding a phosphoglycerate kinase of Fasciola hepatica (FhPGK) and F. hepatica infection.
Microarray analysis of rat immune responses to liver fluke infection following vaccination with Fasciola hepatica phosphoglycerate kinase.
Murine Retroviral but not Human Cellular Promoters Induce In Vivo Erythroid-specific Deregulation that can be Partially Prevented by Insulators.
Infertility
Electrophoresis of phosphoglycerate kinase-2 to determine testicular damage induced by ethylene glycol monomethyl ether and sterility associated with chromosomal abnormality.
Intellectual Disability
A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.
A New 5' Terminal Murine GAPDH Exon Identified Using 5'RACE LaNe.
Altered expression of PGK1 in a family with phosphoglycerate kinase deficiency.
Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Créteil and PGK Amiens.
Intronic mutation in the PGK1 gene may cause recurrent myoglobinuria by aberrant splicing.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Recurrent episodes of myoglobinuria, mental retardation and seizures but no hemolysis in two brothers with phosphoglycerate kinase deficiency.
Recurrent myoglobinuria in a child with mental retardation: phosphoglycerate kinase deficiency.
Iron Overload
Modulation of transduced erythropoietin expression by iron.
l-lactate dehydrogenase deficiency
Myopathies due to enzyme deficiencies.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Leiomyoma
Clonal determination of uterine leiomyomas by analyzing differential inactivation of the X-chromosome-linked phosphoglycerokinase gene.
Compensatory alterations in energy homeostasis characterized in uterine tumors from hereditary leiomyomatosis and renal cell cancer.
[X-chromosome inactivation patterns of different tumor nodules in multiple leiomyomas of uterus]
Leiomyosarcoma
[X-chromosome inactivation patterns of different tumor nodules in multiple leiomyomas of uterus]
Leukemia
Clonal nature of mink cell focus-inducing virus-induced AKR leukemia: studies with X-chromosome inactivation cellular mosaicism.
Clonal nature of spontaneous AKR leukemia: studies utilizing the X-linked enzyme phosphoglycerate kinase.
Correction of ornithine-delta-aminotransferase deficiency in a Chinese hamster ovary cell line mediated by retrovirus gene transfer.
Enhanced inhibition of human immunodeficiency virus type 1 replication by novel lentiviral vectors expressing human immunodeficiency virus type 1 envelope antisense RNA.
Expression of human glucocerebrosidase in murine macrophages: identification of efficient retroviral vectors.
Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells.
Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.
Lentiviral vectors for enhanced gene expression in human hematopoietic cells.
Long-term promoter activity during herpes simplex virus latency.
Prolonged survival of mice with myeloid leukemia by subcutaneous injection of recombinant human G-CSF.
Retrovirus-mediated gene expression in hematopoietic cells correlates inversely with growth factor stimulation.
The detection of normal hidden stem cells during the development of leukemia: assays with PGK isozyme.
[Exploration of the variance in exogenous gene expression driven by the different promoters in leukemia cells].
Leukemia, Erythroblastic, Acute
The silencer of mouse Pgk-2 consists of two discrete DNA elements that individually have no effect.
Leukemia, Myeloid
A new cell line of murine myeloid leukemia with A-type phosphoglycerate kinase as marker isoenzyme.
Clonal origin of radiation-induced myeloid leukemia in mice with cellular mosaicism.
Prolonged survival of mice with myeloid leukemia by subcutaneous injection of recombinant human G-CSF.
Leukemia, Myeloid, Acute
Clonal analysis in acute myeloid leukemia by polymerase chain reaction.
Leukocytosis
Spontaneous loss of Ph chromosome with maintenance of clonal hemopoiesis in an untreated patient with myeloproliferative disease and a long survival.
Liver Neoplasms
[Influence of phosphoglycerate kinase 1 on metastasis and invasion of hepatoma cells and prognosis of liver cancer].
Lung Neoplasms
Colliding primary lung cancers of adenosquamous carcinoma and large cell neuroendocrine carcinoma.
Metabolic protein phosphoglycerate kinase 1 confers lung cancer migration by directly binding HIV Tat specific factor 1.
Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo.
Lymphoma
Clonal haemopoiesis following cytotoxic therapy for lymphoma.
Identification of genuine primary pulmonary NK cell lymphoma via clinicopathologic observation and clonality assay.
Single cell origin of radiation-induced thymic lymphoma in mice with cellular mosaicism.
[Detection of cyclin D1 mRNA by reverse transcription-polymerase chain reaction in paraffin-embedded tissues and its diagnostic significance for mantle cell lymphoma]
Lymphoma, Mantle-Cell
[Detection of cyclin D1 mRNA by reverse transcription-polymerase chain reaction in paraffin-embedded tissues and its diagnostic significance for mantle cell lymphoma]
Lymphoproliferative Disorders
X inactivation as a mechanism of selection against lethal alleles: further investigation of incontinentia pigmenti and X linked lymphoproliferative disease.
Malaria
Glycolytic pathway of the human malaria parasite Plasmodium falciparum: primary sequence analysis of the gene encoding 3-phosphoglycerate kinase and chromosomal mapping studies.
Plasmodium falciparum: identification and purification of the phosphoglycerate kinase of the malaria parasite.
The use of enzymopathic human red cells in the study of malarial parasite glucose metabolism.
Malaria, Falciparum
The use of enzymopathic human red cells in the study of malarial parasite glucose metabolism.
Melanoma
[Silencing of PKG1 expression enhances the efficacy of vemurafenib against melanoma cell].
Meningioma
Clonal origin of recurrent meningiomas.
Menkes Kinky Hair Syndrome
Analysis of Mnk, the murine homologue of the locus for Menkes disease, in normal and mottled (Mo) mice.
Localization of the translocation breakpoint in a female with Menkes syndrome to Xq13.2-q13.3 proximal to PGK-1.
Mental Retardation, X-Linked
22-Mb integrated physical and genetic map based on YAC/STS content spanning the interval DXS1125-DXS95 in human Xq12-q21.31.
X-linked mental retardation exhibiting linkage to DXS255 and PGKP1: a new MRX family (MRX14) with localization in the pericentromeric region.
Migraine Disorders
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Mitochondrial Myopathies
Metabolic myopathies.
Mouth Neoplasms
5-Methoxytryptophan-dependent inhibition of oral squamous cell carcinoma metastasis.
Movement Disorders
Exposure to Phosphoglycerate Kinase 1 Activators and Incidence of Parkinson's Disease.
Multiple Endocrine Neoplasia
Clonal emergence in uremic parathyroid hyperplasia is not related to MEN1 gene abnormality.
Multiple Endocrine Neoplasia Type 1
Clonal emergence in uremic parathyroid hyperplasia is not related to MEN1 gene abnormality.
Muscle Cramp
Molecular genetic heterogeneity of phosphoglycerate kinase (PGK) deficiency.
Muscle Hypotonia
Neonatal metabolic myopathies.
Muscular Diseases
Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?
Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Créteil and PGK Amiens.
Level of residual enzyme activity modulates the phenotype in phosphoglycerate kinase deficiency.
Molecular genetic heterogeneity of phosphoglycerate kinase (PGK) deficiency.
Myopathy and parkinsonism in phosphoglycerate kinase deficiency.
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
Parkinsonism in PGK1 deficiency implicates the glycolytic pathway in nigrostriatal dysfunction.
Phosphoglycerate kinase deficiency due to a novel mutation (c. 1180A>G) manifesting as chronic hemolytic anemia in a Japanese boy.
Phosphoglycerate kinase deficiency myopathy: biochemical and immunological studies of the mutant enzyme.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Slowly progressive leukodystrophy in an adolescent male with phosphoglycerate kinase deficiency.
Therapeutic Benefit of Blood Transfusion in a Patient With Novel PGK1 Mutation (c.461T>C [p.L154P]).
Muscular Dystrophy, Duchenne
Comparison of the physical and recombination maps of the mouse X chromosome.
Myalgia
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphoglycerate kinase deficiency: biochemical and molecular genetic studies in a new myopathic variant (PGK Alberta)
Myelodysplastic Syndromes
Clonal analysis of myelodysplastic syndromes: evidence of multipotent stem cell origin.
Clonal involvement of granulocytes and monocytes, but not of T and B lymphocytes and natural killer cells in patients with myelodysplasia: analysis by X-linked restriction fragment length polymorphisms and polymerase chain reaction of the phosphoglycerate kinase gene.
Clonality in myelodysplastic syndromes: demonstration of pluripotent stem cell origin using X-linked restriction fragment length polymorphisms.
Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction.
Detection of monoclonal hematopoiesis using restriction fragment length polymorphism (RFLP) of phosphoglycerokinase (PGK) gene in a patient with hypoplastic myelodysplastic syndrome (MDS).
In vivo effects of granulocyte-macrophage colony-stimulating factor and interleukin-3 on clonal and non-clonal cell populations in patients with clonal hematopoietic disorders.
Myeloproliferative Disorders
Clonal analysis of chronic myeloproliferative disorders using X-linked DNA polymorphisms.
Clonal analysis of transient myeloproliferative disorder in Down's syndrome.
Clonality in chronic myeloproliferative disorders defined by X-chromosome linked probes: demonstration of heterogeneity in lineage involvement.
Myeloproliferative disorders: usefulness of X-linked probes in diagnosis.
Myoglobinuria
A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria.
Intronic mutation in the PGK1 gene may cause recurrent myoglobinuria by aberrant splicing.
Metabolic causes of myoglobinuria.
Metabolic myopathies.
Molecular genetic heterogeneity of phosphoglycerate kinase (PGK) deficiency.
Neonatal metabolic myopathies.
Phosphoglycerate kinase deficiency myopathy: biochemical and immunological studies of the mutant enzyme.
Phosphoglycerate kinase deficiency: a new cause of recurrent myoglobinuria.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Phosphoglycerate kinase deficiency: biochemical and molecular genetic studies in a new myopathic variant (PGK Alberta)
Recurrent episodes of myoglobinuria, mental retardation and seizures but no hemolysis in two brothers with phosphoglycerate kinase deficiency.
Recurrent myoglobinuria in a child with mental retardation: phosphoglycerate kinase deficiency.
Retarded and aberrant splicings caused by single exon mutation in a phosphoglycerate kinase variant.
[1H and 31P magnetic resonance spectroscopy study of a case of phosphoglycerate kinase deficiency]
[Myoglobinuria due to enzyme abnormalities in glycolytic pathway--especially lactate dehydrogenase M subunit deficiency]
[Phosphoglycerate kinase deficiency with recurrent myoglobinuria: morphological and biochemical analysis]
Neoplasm Metastasis
5-Methoxytryptophan-dependent inhibition of oral squamous cell carcinoma metastasis.
Evidence by cellular mosaicism for monoclonal metastasis of spontaneous mouse mammary tumors.
FLNA and PGK1 are Two Potential Markers for Progression in Hepatocellular Carcinoma.
Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.
Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging.
shRNA-mediated inhibition of PhosphoGlycerate Kinase 1 (PGK1) enhances cytotoxicity of intraperitoneal chemotherapy in peritoneal metastasis of gastric origin.
[Influence of phosphoglycerate kinase 1 on metastasis and invasion of hepatoma cells and prognosis of liver cancer].
Neoplasms
A novel clonality assay for the mouse: application to hepatocellular carcinomas induced with diethylnitrosamine.
Analysis of clonality in archival tissues by polymerase chain reaction amplification of PGK-1.
Analysis of meningiomas by methylation- and transcription-based clonality assays.
Antrodia cinnamomea Inhibits Migration in Human Hepatocellular Carcinoma Cells: The Role of ERp57 and PGK-1.
Biological regulation through protein disulfide bond cleavage.
Blood level of phosphoglycerate kinase does not correlate with presence or extent of tumor.
Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression.
Choice of endogenous control for gene expression in nonsmall cell lung cancer.
Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction.
Clonal analysis of sporadic pancreatic endocrine tumours.
Clonal composition of benign and malignant human thyroid tumors.
Clonal emergence in uremic parathyroid hyperplasia is not related to MEN1 gene abnormality.
Clonal nature of mink cell focus-inducing virus-induced AKR leukemia: studies with X-chromosome inactivation cellular mosaicism.
Clonal nature of spontaneous AKR leukemia: studies utilizing the X-linked enzyme phosphoglycerate kinase.
Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies.
Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation.
Clonal origin of skin and bone tumors produced by repeated beta-irradiation in mosaic cell mice.
Clonal origin of spontaneous multiple mammary tumors in mice with cellular mosaicism.
Clonal origin of tumors induced by ultraviolet radiation.
Clonality in hepatocellular carcinoma: analysis of methylation pattern of polymorphic X-chromosome-linked phosphoglycerate kinase gene in females.
Clonality of multiple uterine leiomyomas.
Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor (HIF)-1{alpha}.
Development of cartilage-like tissue from androgen-dependent Shionogi carcinoma 115 in androgen-depleted hosts.
Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system.
DNA methylation changes in human testicular cancer.
Dose response of monoclonal tumor induction with 3-methylcholanthrene in mosaic mice.
Downregulation of long non-protein coding RNA MVIH impairs glioblastoma cell proliferation and invasion through an miR-302a-dependent mechanism.
Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma.
Effect of solvents on methylcholanthrene-induced carcinogenesis in mice.
Enzyme activities at the surface of intact Ehrlich tumor cells with albumin in the isotonic assay medium.
Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion.
Evidence by cellular mosaicism for monoclonal metastasis of spontaneous mouse mammary tumors.
Evidence concerning the clonal nature of chemically induced tumors: phosphoglycerate kinase-1 isozyme patterns in chemically induced fibrosarcomas.
Evidence for single-cell origin of 3-methylcholanthrene-induced fibrosarcomas in mice with cellular mosaicism.
FOXO3A-induced LINC00926 suppresses breast tumor growth and metastasis through inhibition of PGK1-mediated Warburg effect.
Gene therapy for hepatocellular carcinoma based on tumour-selective suicide gene expression using the alpha-fetoprotein (AFP) enhancer and a housekeeping gene promoter.
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Identification of a novel non-ATP-competitive protein kinase inhibitor of PGK1 from marine nature products.
In situ identification of host derived infiltrating cells in chemically induced fibrosarcomas of interspecific chimeric mice.
In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors.
Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism.
Influence of hypoxia-dependent factors on the progression of neuroblastoma.
Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms.
Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.
Lentiviral vector design for optimal TCR gene expression in the transduction of PBL and TIL.
Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis.
MicroRNA-16-1-3p Represses Breast Tumor Growth and Metastasis by Inhibiting PGK1-Mediated Warburg Effect.
miR-548c-5p inhibits colorectal cancer cell proliferation by targeting PGK1.
Multicellular origin of fibrosarcomas in mice induced by the chemical carcinogen 3-methylcholanthrene.
Nucleotide-binding domain of phosphoglycerate kinase 1 reduces tumor growth by suppressing COX-2 expression.
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.
PGK1 as predictor of CXCR4 expression, bone marrow metastases and survival in neuroblastoma.
pH-dependent relationship between thermodynamic and kinetic stability in the denaturation of human phosphoglycerate kinase 1.
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52.
Phosphoglycerate kinase 1 (PGK1) in cancer: A promising target for diagnosis and therapy.
Phosphoglycerate kinase 1 as a promoter of metastasis in colon cancer.
Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging.
Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo.
Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase.
Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer.
Plasmin reduction by phosphoglycerate kinase is a thiol-independent process.
Polyclonal origin of parathyroid tumors is common and is associated with multiple gland disease in primary hyperparathyroidism.
Probable clonal development of foreign-body-induced murine sarcomas.
Protein alterations in infiltrating ductal carcinomas of the breast as detected by nonequilibrium pH gradient electrophoresis and mass spectrometry.
Protein profiles associated with survival in lung adenocarcinoma.
Recent progress in breast cancer research at Osaka Medical Center for Cancer and Cardiovascular Diseases.
Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases.
Single-cell origin of bladder cancer induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice with cellular mosaicism.
Solitary polyclonal autonomous thyroid nodule: a rare cause of childhood hyperthyroidism.
Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers.
Specificity of tumour associated transplantation antigens (TATA) of different clones from the same tumour.
Stable Lyonization of X-linked pgk-1 gene during aging in normal tissues and tumors of mice carrying Searle's translocation.
Targeted expression of SV40 large tumour antigen (TAg) induces a transient enhancement of spermatocyte proliferation and apoptosis.
Targeting gene therapy to cancer: a review.
Test of recurrence after experimental radiation therapy of chemically induced autochthonous tumors in mosaic mice.
The effect of CELLFOODTM on radiotherapy or combined chemoradiotherapy: preclinical evidence.
The expression of MMP19 and its clinical significance in glioma.
The identification of auto-antibodies in pancreatic cancer patient sera using a naturally fractionated Panc-1 cell line.
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray.
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.
Two proliferation-related proteins, TYMS and PGK1, could be new cytotoxic T lymphocyte-directed tumor-associated antigens of HLA-A2+ colon cancer.
Urokinase receptor expression involves tyrosine phosphorylation of phosphoglycerate kinase.
Use of the PSA enhancer core element to modulate the expression of prostate- and non-prostate-specific basal promoters in a lentiviral vector context.
X-chromosomal inactivation analysis of uterine leiomyomas reveals a common clonal origin of different tumor nodules in some multiple leiomyomas.
X-chromosome inactivation patterns using HPRT and PGK polymorphisms in haematologically normal and post-chemotherapy females.
[Clonal analysis of hepatocellular carcinoma]
[Detection of FUS-CHOP fusion gene in paraffin-embedded tissues and its clinicopathologic significance for myxoid/round cell liposarcomas]
[Proteome study of colorectal cancer genesis and hepatic metastasis]
Nervous System Diseases
Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?
Molecular defect of a phosphoglycerate kinase variant associated with haemolytic anaemia and neurological disorders in a large kindred.
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
Neuroblastoma
Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor (HIF)-1{alpha}.
Neurodegenerative Diseases
Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
Neurofibroma
The neurofibroma in von Recklinghausen neurofibromatosis has a unicellular origin.
Neuromuscular Diseases
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
Neuromuscular Manifestations
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
Osteoarthritis
A proteomic study of protein variation between osteopenic and age-matched control bone tissue.
Osteomalacia
PDGFB-based stem cell gene therapy increases bone strength in the mouse.
Osteosarcoma
Clonal origin of skin and bone tumors produced by repeated beta-irradiation in mosaic cell mice.
Ovarian Neoplasms
Down-regulation of Ras-related protein Rab 5C-dependent endocytosis and glycolysis in cisplatin-resistant ovarian cancer cell lines.
Pancreatic Neoplasms
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray.
Pancreatitis, Chronic
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray.
Papilloma
Clonal analysis of solitary intraductal papilloma of the breast by means of polymerase chain reaction.
Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism.
Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.
Sequential studies of skin tumorigenesis in PGK mosaic mice: the effect of repeated exposure to a carcinogen on regressed mouse skin papillomas.
Sequential studies of skin tumorigenesis in phosphoglycerate kinase mosaic mice: effect of resumption of promotion on regressed papillomas.
Studies of skin tumorigenesis in PGK mosaic mice: many promoter-independent papillomas and carcinomas do not develop from pre-existing promoter-dependent papillomas.
Papilloma, Intraductal
Clonal analysis of solitary intraductal papilloma of the breast by means of polymerase chain reaction.
Parathyroid Neoplasms
Clonal analysis of parathyroid adenomas by means of the polymerase chain reaction.
The role of hyperplasia in multiple parathyroid adenomas.
Parkinson Disease
Exposure to Phosphoglycerate Kinase 1 Activators and Incidence of Parkinson's Disease.
Parkinsonian Disorders
Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?
Levodopa Responsive Parkinsonism in Two Patients With Phosphoglycerate Kinase Deficiency.
Myopathy and parkinsonism in phosphoglycerate kinase deficiency.
Novel Drosophila model for parkinsonism by targeting phosphoglycerate kinase.
Progress and problems in muscle glycogenoses.
X-Linked Parkinsonism: Phenotypic and Genetic Heterogeneity.
Peritoneal Neoplasms
PGK1 a potential marker for peritoneal dissemination in gastric cancer.
Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer.
phosphoglucomutase (alpha-d-glucose-1,6-bisphosphate-dependent) deficiency
[Biochemical analysis using biopsied muscle in 72 patients with metabolic myopathies]
phosphoglycerate kinase deficiency
1,3-Diphosphoglycerate in phosphoglycerate kinase deficiency.
A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.
A negative waveform in the scotopic response in a patient with phosphoglycerate kinase deficiency: a visual electrophysiology report.
A new case of phosphoglycerate kinase deficiency: PGK Creteil associated with rhabdomyolysis and lacking hemolytic anemia.
A new variant of phosphoglycerate kinase deficiency (p.I371K) with multiple tissue involvement: Molecular and functional characterization.
A novel missense mutation (837T-->C) in the phosphoglycerate kinase gene of a patient with a myopathic form of phosphoglycerate kinase deficiency.
A phosphoglycerate kinase variant, PGK Uppsala, associated with hemolytic anemia.
A screening test for phosphoglycerate kinase deficiency.
A splice junction mutation in a new myopathic variant of phosphoglycerate kinase deficiency (PGK North Carolina).
Altered expression of PGK1 in a family with phosphoglycerate kinase deficiency.
Calmodulin binds to and inhibits the activity of phosphoglycerate kinase.
Characterization of a phosphoglycerate kinase deficiency variants not associated with hemolytic anemia.
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?
Enzymatic and metabolic characterization of the phosphoglycerate kinase deficiency associated with chronic hemolytic anemia caused by the PGK-Barcelona mutation.
Enzymatic diagnosis in non-spherocytic hemolytic anemia.
Erythrocyte and leukocyte phosphoglycerate kinase deficiency with neurologic disease.
Erythrocyte phosphoglycerate kinase deficiency: enzymatic and oxygen binding studies.
Evidence of the decreased muscle enzyme activity in erythrocyte phosphoglycerate kinase deficiency.
Familial phosphoglycerate kinase deficiency associated with rhabdomyolysis and acute renal failure: abnormality in mRNA splicing?
Genome-wide identification of pseudogenes capable of disease-causing gene conversion.
Glucose phosphate isomerase (GPI) Tadikonda: Characterization of a novel Pro340Ser mutation.
Hereditary deficiency of phosphoglycerate kinase: a new variant in erythrocytes and leucocytes, not associated with haemolytic anaemia.
Hereditary hemolytic anemia associated with phosphoglycerate kinase deficiency in erythrocytes and leukocytes. A probable X-chromosome-linked syndrome.
Hereditary hemolytic anemia: association with phosphoglycerate kinase deficiency in erythrocytes and leukocytes.
Human erythrocyte phosphoglycerate kinase deficiency: presence in a deficient patient of a stable variant with lowered catalytic activity.
Immunochemical studies on phosphoglycerate kinase deficiency.
Insights into human phosphoglycerate kinase 1 deficiency as a conformational disease from biochemical, biophysical, and in vitro expression analyses.
Lack of effect of increased 2,3-diphosphoglycerate on flux through the oxidative pathway in phosphoglycerate kinase deficiency.
Level of residual enzyme activity modulates the phenotype in phosphoglycerate kinase deficiency.
Levodopa Responsive Parkinsonism in Two Patients With Phosphoglycerate Kinase Deficiency.
Metabolic causes of myoglobinuria.
Mitochondrial changes in muscle phosphoglycerate kinase deficiency.
Molecular genetic heterogeneity of phosphoglycerate kinase (PGK) deficiency.
Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency.
Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line.
Myopathic form of phosphoglycerate kinase (PGK) deficiency: a new case and pathogenic considerations.
Myopathy and parkinsonism in phosphoglycerate kinase deficiency.
Neutrophil function in congenital phosphoglycerate kinase deficiency.
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
Parkinsonism in PGK1 deficiency implicates the glycolytic pathway in nigrostriatal dysfunction.
PAS domain-containing phosphoglycerate kinase deficiency in Leishmania major results in increased autophagosome formation and cell death.
PGK deficiency.
Phosphoglycerate kinase deficiency due to a novel mutation (c. 1180A>G) manifesting as chronic hemolytic anemia in a Japanese boy.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphoglycerate kinase deficiency myopathy: biochemical and immunological studies of the mutant enzyme.
Phosphoglycerate kinase deficiency.
Phosphoglycerate kinase deficiency: A nationwide multicenter retrospective study.
Phosphoglycerate kinase deficiency: a new cause of recurrent myoglobinuria.
Phosphoglycerate kinase deficiency: an adult myopathic form with a novel mutation.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Phosphoglycerate kinase deficiency: biochemical and molecular genetic studies in a new myopathic variant (PGK Alberta)
Phosphoglycerate kinase deficiency: biochemical studies on hair follicles.
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
Progress and problems in muscle glycogenoses.
Recurrent episodes of myoglobinuria, mental retardation and seizures but no hemolysis in two brothers with phosphoglycerate kinase deficiency.
Recurrent myoglobinuria in a child with mental retardation: phosphoglycerate kinase deficiency.
Red cell enzymopathies as a model of inborn errors of metabolism.
Red cell glycolysis in a case of 3-phosphoglycerate kinase deficiency.
Red cell phosphoglycerate kinase deficiency. A new cause of non-spherocytic hemolytic anemia.
Slowly progressive leukodystrophy in an adolescent male with phosphoglycerate kinase deficiency.
Structural and energetic basis of protein kinetic destabilization in human phosphoglycerate kinase 1 deficiency.
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Therapeutic Benefit of Blood Transfusion in a Patient With Novel PGK1 Mutation (c.461T>C [p.L154P]).
Tissue levels of glycolytic enzymes in phosphoglycerate kinase deficiency.
X-Linked Parkinsonism: Phenotypic and Genetic Heterogeneity.
[1H and 31P magnetic resonance spectroscopy study of a case of phosphoglycerate kinase deficiency]
[A modification of the fluorescent stain method for identifying a deficit of erythrocyte phosphoglycerate kinase in mass screening]
[Biochemical analysis using biopsied muscle in 72 patients with metabolic myopathies]
[Clinical and biochemical analysis of 27 patients with myoglobinuria of unknown causes]
[Congenital hemolytic anemia associated with phosphoglycerate kinase deficiency in erythrocytes, polynuclear cells and lymphocytes]
[Congenital phosphoglycerate kinase deficiency]
[Erythrocyte and leucocyte 3-phosphoglycerate kinase deficiency. Studies of properties of the enzyme, phagocytic activity of the polymorphonuclear leucoytes and a review of the literature]
[Phosphoglycerate kinase deficiency with recurrent myoglobinuria: morphological and biochemical analysis]
[Phosphoglycerate kinase deficiency]
[Studies on erythrocye and leukocyte phosphoglycerate kinase deficiency with neurologic disease (author's transl)]
phosphorylase kinase deficiency
Metabolic causes of myoglobinuria.
Phyllodes Tumor
Clonal analysis of fibroadenoma and phyllodes tumor of the breast.
Recent progress in breast cancer research at Osaka Medical Center for Cancer and Cardiovascular Diseases.
Pituitary ACTH Hypersecretion
Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease.
Pituitary Neoplasms
Clinically nonfunctioning pituitary tumors are monoclonal in origin.
Corticotroph carcinoma presenting as a silent corticotroph adenoma.
Polycythemia
The application of X-chromosome gene probes to the diagnosis of myeloproliferative disease.
Polycythemia Vera
Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction.
Prostatic Neoplasms
A hemizygous short tandem repeat polymorphism 3' to the human phosphoglycerate kinase gene.
Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression.
Prostatitis
X Chromosomal short tandem repeat polymorphisms near the phosphoglycerate kinase gene in men with chronic prostatitis.
Protein Deficiency
Neonatal metabolic myopathies.
Pulmonary Emphysema
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema.
Pulmonary Sclerosing Hemangioma
Determination of clonal status of pulmonary sclerosing hemangioma with X-chromosome inactivation mosaicism and polymorphism of phosphoglycerate kinase and androgen receptor genes.
Gene expression and clonality analysis of the androgen receptor and phosphoglycerate kinase genes in polygonal cells and cuboidal cells in so-called pulmonary sclerosing hemangioma.
[Study of androgen receptor and phosphoglycerate kinase gene polymorphism in major cellular components of the so-called pulmonary sclerosing hemangioma]
Retinal Degeneration
Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina.
Retinal Dystrophies
A negative waveform in the scotopic response in a patient with phosphoglycerate kinase deficiency: a visual electrophysiology report.
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Retinitis Pigmentosa
Genome-wide identification of pseudogenes capable of disease-causing gene conversion.
Phosphoglycerate kinase deficiency: biochemical and molecular genetic studies in a new myopathic variant (PGK Alberta)
Rhabdomyolysis
A new case of phosphoglycerate kinase deficiency: PGK Creteil associated with rhabdomyolysis and lacking hemolytic anemia.
A novel missense mutation (1060G --> C) in the phosphoglycerate kinase gene in a Japanese boy with chronic haemolytic anaemia, developmental delay and rhabdomyolysis.
Familial phosphoglycerate kinase deficiency associated with rhabdomyolysis and acute renal failure: abnormality in mRNA splicing?
Parkinsonism in PGK1 deficiency implicates the glycolytic pathway in nigrostriatal dysfunction.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphoglycerate kinase San Francisco: a new variant associated with hemolytic anemia but not with neuromuscular manifestations.
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Sarcoma
Expression of human glucocerebrosidase in murine macrophages: identification of efficient retroviral vectors.
Lentiviral-mediated correction of MPS VI cells and gene transfer to joint tissues.
Lentivirus-mediated gene transfer to the rat, ovine and human cornea.
Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells.
Probable clonal development of foreign-body-induced murine sarcomas.
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
Test of recurrence after experimental radiation therapy of chemically induced autochthonous tumors in mosaic mice.
Sarcoma, Avian
Efficient marking of neural stem cell-derived neurons with a modified murine embryonic stem cell virus, MESV2.
Expression of bacterial cysteine biosynthesis genes in transgenic mice and sheep: toward a new in vivo amino acid biosynthesis pathway and improved wool growth.
Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions.
Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.
Transgenic sheep and wool growth: possibilities and current status.
Schistosomiasis
Cloning, expression and enzymatic characterization of 3-phosphoglycerate kinase from Schistosoma japonicum.
Immune response to Schistosoma mansoni phosphoglycerate kinase during natural and experimental infection: identification of a schistosome-specific B-cell epitope.
Seizures
A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.
Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria.
Recurrent episodes of myoglobinuria, mental retardation and seizures but no hemolysis in two brothers with phosphoglycerate kinase deficiency.
The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA.
Spinal Cord Injuries
Cell adhesion molecule l1-transfected embryonic stem cells with enhanced survival support regrowth of corticospinal tract axons in mice after spinal cord injury.
Spinal Dysraphism
A human autosomal phosphoglycerate kinase locus maps near the HLA cluster.
Starvation
Phosphate Starvation Inducible ;Bypasses' of Adenylate and Phosphate Dependent Glycolytic Enzymes in Brassica nigra Suspension Cells.
steryl-sulfatase deficiency
Dosage of the Sts gene in the mouse.
Stomach Neoplasms
Induction of tumor stem cell differentiation-novel strategy to overcome therapy resistance in gastric cancer.
Metabolic alteration--Overcoming therapy resistance in gastric cancer via PGK-1 inhibition in a combined therapy with standard chemotherapeutics.
PGK1 a potential marker for peritoneal dissemination in gastric cancer.
Phosphoglycerate kinase 1 a promoting enzyme for peritoneal dissemination in gastric cancer.
Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging.
Teratocarcinoma
Genetic activity of X chromosomes in pluripotent female teratocarcinoma cells and their differentiated progeny.
Thrombocythemia, Essential
In vivo effects of granulocyte-macrophage colony-stimulating factor and interleukin-3 on clonal and non-clonal cell populations in patients with clonal hematopoietic disorders.
Thrombosis
Pneumococcal phosphoglycerate kinase interacts with plasminogen and its tissue activator.
Variations in platelet protein associated with arterial thrombosis.
Thymoma
Clonal nature of mink cell focus-inducing virus-induced AKR leukemia: studies with X-chromosome inactivation cellular mosaicism.
Clonal nature of spontaneous AKR leukemia: studies utilizing the X-linked enzyme phosphoglycerate kinase.
Thyroid Nodule
Clonal analysis of solitary follicular nodules in the thyroid.
Trypanosomiasis, African
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
Urinary Bladder Neoplasms
Single-cell origin of bladder cancer induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice with cellular mosaicism.
Urogenital Abnormalities
Short tandem repeat polymorphism linkage to the androgen receptor gene in prostate carcinoma.
Urogenital Diseases
A hemizygous short tandem repeat polymorphism 3' to the human phosphoglycerate kinase gene.
Vesicular Stomatitis
Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells.
Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro.
Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter.
X-Linked Combined Immunodeficiency Diseases
Comparative mapping of canine and human proximal Xq and genetic analysis of canine X-linked severe combined immunodeficiency.