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Disease on EC 2.7.1.35 - pyridoxal kinase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Anemia, Sideroblastic
Erythrocyte pyridoxine kinase levels in patients with sideroblastic anemia.
Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients.
Brain Diseases
Biomedical aspects of pyridoxal 5'-phosphate availability.
Carcinoma
Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses.
Nephrotoxicity Profile of Cadmium Revealed by Proteomics in Mouse Kidney.
[Pyridoxal kinase activity in human tumor tissues]
Carcinoma, Hepatocellular
Vitamin B6 metabolism in liver and liver-derived tumors.
Carcinoma, Non-Small-Cell Lung
Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses.
Negative prognostic value of high levels of intracellular poly(ADP-ribose) in non-small cell lung cancer.
Down Syndrome
Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain.
Increased activity of pyridoxal kinase in tongue in Down's syndrome.
Epilepsy
Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies.
[Distribution and activity of pyridoxal kinase in human brain during ontogenesis]
Leishmaniasis, Visceral
Evaluation of Leishmania infantum pyridoxal kinase protein for the diagnosis of human and canine visceral leishmaniasis.
Leishmania infantum pyridoxal kinase evaluated in a recombinant protein and DNA vaccine to protects against visceral leishmaniasis.
Leukemia, Myeloid, Acute
Vitamin B6 Fuels Acute Myeloid Leukemia Growth.
Lung Neoplasms
Negative prognostic value of high levels of intracellular poly(ADP-ribose) in non-small cell lung cancer.
Lymphopenia
Inhibition of human pyridoxal kinase by 2-acetyl-4-((1R,2S,3R)-1,2,3,4-tetrahydroxybutyl)imidazole (THI).
Malaria
The antimalarial drugs chloroquine and primaquine inhibit pyridoxal kinase, an essential enzyme for vitamin B6 production.
Neoplasms
Pyridoxal kinase and poly(ADP-ribose) affect the immune microenvironment of locally advanced cancers.
Vitamin B6 metabolism in Morris hepatomas.
[Pyridoxal kinase activity in human tumor tissues]
Nervous System Diseases
Biomedical aspects of pyridoxal 5'-phosphate availability.
Ovarian Neoplasms
[Pyridoxal kinase (PDXK) promotes the proliferation of serous ovarian cancer cells and is associated with poor prognosis].
Parkinson Disease
A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy.
Association of pyridoxal kinase and Parkinson disease.
Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene.
pyridoxal kinase deficiency
Apparent pyridoxine transport mutants of Escherichia coli with pyridoxal kinase deficiency.
Seizures
Biomedical aspects of pyridoxal 5'-phosphate availability.
Changes in pyridoxal kinase immunoreactivity in the gerbil hippocampus following spontaneous seizure.
Correlative changes of pyridoxal kinase pyridoxal-5'-phosphate and glutamate decarboxylase in brain, during drug-induced convulsions.
Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies.
Seizure susceptibility in the developing mouse and its relationship to glutamate decarboxylase and pyridoxal phosphate in brain.
The status of vitamin B6 metabolism in brains of genetically epilepsy-prone rats.
Vigabatrin inhibits pyridoxine-5'-phosphate oxidase, not pyridoxal kinase in the hippocampus of seizure prone gerbils.
Stomach Neoplasms
The differential proteome profile of stomach cancer: identification of the biomarker candidates.
Vitamin B 6 Deficiency
Evidence of a theophylline-induced vitamin B6 deficiency caused by noncompetitive inhibition of pyridoxal kinase.