Information on EC 2.7.1.196 - protein-Npi-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)

The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.7.1.196
-
RECOMMENDED NAME
GeneOntology No.
protein-Npi-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[protein]-Npi-phospho-L-histidine + N,N'-diacetylchitobiose[side 1] = [protein]-L-histidine + N,N'-diacetylchitobiose 6'-phosphate[side 2]
show the reaction diagram
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
protein-Npi-phospho-L-histidine:N,N'-diacetylchitobiose Npi-phosphotransferase
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
[protein]-Npi-phospho-L-histidine + N,N'-diacetylchitobiose[side 1]
[protein]-L-histidine + N,N'-diacetylchitobiose 6'-phosphate[side 2]
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
[protein]-Npi-phospho-L-histidine + N,N'-diacetylchitobiose[side 1]
[protein]-L-histidine + N,N'-diacetylchitobiose 6'-phosphate[side 2]
show the reaction diagram
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10480
-
subunit IIBChb, sedimentation equilibrium analysis
11431
-
1 * 11431, subunit IIBChb, calculated from amino acid sequence
12748
-
2 * 12748, subunit IIAChb, calculated from amino acid sequence
25200
-
subunit IIAChb, sedimentation equilibrium analysis
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
homodimer
-
2 * 12748, subunit IIAChb, calculated from amino acid sequence
monomer
-
1 * 11431, subunit IIBChb, calculated from amino acid sequence