Reference on EC 2.7.1.158 - inositol-pentakisphosphate 2-kinase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
York, J.D.; Odom, A.R.; Murphy, R.; Ives, E.B.; Wente, S.R.
A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export
Science
285
96-100
1999
Saccharomyces cerevisiae
Ongusaga, P.P.; Hughes, P.J.; Davey, J.; Michell, R.H.
Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins(1,4,5)P3 and osmotic regulation
Biochem. J.
335
671-679
1998
Schizosaccharomyces pombe
-
Sweetman, D.; Johnson, S.; Caddick, S.E.; Hanke, D.E.; Brearley, C.A.
Characterization of an Arabidopsis inositol 1,3,4,5,6-pentakisphosphate 2-kinase (AtIPK1)
Biochem. J.
394
95-103
2006
Arabidopsis thaliana
Phillippy, B.Q.; Ullah, A.H.J.; Ehrlich, K.C.
Purification and some properties of inositol 1,3,4,5,6-pentakis phosphate 2-kinase from immature soybean seeds
J. Biol. Chem.
269
28393-28399
1994
Glycine max
Ives, E.B.; Nichols, J.; Wente, S.R.; York, J.D.
Biochemical and functional characterization of inositol 1,3,4,5,6-pentakisphosphate 2-kinases
J. Biol. Chem.
275
36575-36583
2000
Saccharomyces cerevisiae, Schizosaccharomyces pombe (Q9USK0), Schizosaccharomyces pombe
Verbsky, J.W.; Wilson, M.P.; Kisseleva, M.V.; Majerus, P.W.; Wente, S.R.
The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase
J. Biol. Chem.
277
31857-31862
2002
Homo sapiens
Miller, A.L.; Suntharalingam, N.; et al.
Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway
J. Biol. Chem.
279
51022-51032
2004
Saccharomyces cerevisiae
Fujii, M.; York, J.D.
A role for rat inositol polyphosphate kinases rIPK2 and rIPK1 in inositol pentakisphosphate and inositol hexakisphosphate production in rat-1 cells
J. Biol. Chem.
280
1156-1164
2005
Rattus norvegicus, Rattus norvegicus (Q5PXE9)
Verbsky, J.; Lavine, K.; Majerus, P.W.
Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
Proc. Natl. Acad. Sci. USA
102
8448-8453
2005
Mus musculus
Brehm, M.A.; Schenk, T.M.; Zhou, X.; Fanick, W.; Lin, H.; Windhorst, S.; Nalaskowski, M.M.; Kobras, M.; Shears, S.B.; Mayr, G.W.
Intracellular localization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Biochem. J.
408
335-345
2007
Homo sapiens
Sun, Y.; Thompson, M.; Lin, G.; Butler, H.; Gao, Z.; Thornburgh, S.; Yau, K.; Smith, D.A.; Shukla, V.K.
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase from maize: molecular and biochemical characterization
Plant Physiol.
144
1278-1291
2007
Zea mays, Zea mays (A4GWX8), Zea mays (A6YH13)
Caddick, S.E.; Harrison, C.J.; Stavridou, I.; Mitchell, J.L.; Hemmings, A.M.; Brearley, C.A.
A Solanum tuberosum inositol phosphate kinase (StITPK1) displaying inositol phosphate-inositol phosphate and inositol phosphate-ADP phosphotransferase activities
FEBS Lett.
582
1731-1737
2008
Solanum tuberosum (A4H2J0), Solanum tuberosum
Sarmah, B.; Wente, S.R.
Dual functions for the Schizosaccharomyces pombe inositol kinase Ipk1 in nuclear mRNA export and polarized cell growth
Eukaryot. Cell
8
134-146
2009
Schizosaccharomyces pombe (Q9USK0), Schizosaccharomyces pombe
Poehlmann, J.; Fleig, U.
Asp1, a conserved 1/3 inositol polyphosphate kinase, regulates the dimorphic switch in Schizosaccharomyces pombe
Mol. Cell. Biol.
30
4535-4547
2010
Schizosaccharomyces pombe
Wundenberg, T.; Grabinski, N.; Lin, H.; Mayr, G.W.
Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio
Biochem. J.
462
173-184
2014
Homo sapiens, Rattus norvegicus
Chanduri, M.; Rai, A.; Malla, A.B.; Wu, M.; Fiedler, D.; Mallik, R.; Bhandari, R.
Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport
Biochem. J.
473
3031-3047
2016
Mus musculus (Q6PD10)
Wang, H.; Godage, H.Y.; Riley, A.M.; Weaver, J.D.; Shears, S.B.; Potter, B.V.
Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery
Chem. Biol.
21
689-699
2014
Homo sapiens
Gosein, V.; Miller, G.J.
Roles of phosphate recognition in inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) substrate binding and activation
J. Biol. Chem.
288
26908-26913
2013
Arabidopsis thaliana (Q93YN9)
Gosein, V.; Miller, G.J.
Conformational stability of inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IPK1) dictates its substrate selectivity
J. Biol. Chem.
288
36788-36795
2013
Arabidopsis thaliana
Brehm, M.; Wundenberg, T.; Williams, J.; Mayr, G.; Shears, S.
A non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA
J. Cell Sci.
126
437-444
2013
Homo sapiens
-
Sun, Y.Y.; Xu, W.Z.; Wu, L.; Wang, R.Z.; He, Z.Y.; Ma, M.
An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance
Plant Cell Environ.
39
416-426
2016
Arabidopsis thaliana (Q93YN9), Arabidopsis thaliana
Kuo, H.F.; Chang, T.Y.; Chiang, S.F.; Wang, W.D.; Charng, Y.Y.; Chiou, T.J.
Arabidopsis inositol pentakisphosphate 2-kinase, AtIPK1, is required for growth and modulates phosphate homeostasis at the transcriptional level
Plant J.
80
503-515
2014
Arabidopsis thaliana (Q93YN9)
Yu, J.; Saiardi, A.; Greenwood, J.S.; Bewley, J.D.
Molecular and biochemical identification of inositol 1,3,4,5,6-pentakisphosphate 2-kinase encoding mRNA variants in castor bean (Ricinus communis L.) seeds
Planta
239
965-977
2014
Ricinus communis
Basak, N.; Krishnan, V.; Pandey, V.; Punjabi, M.; Hada, A.; Marathe, A.; Jolly, M.; Palaka, B.K.; Ampasala, D.R.; Sachdev, A.
Expression profiling and in silico homology modeling of inositol pentakisphosphate 2-kinase, a potential candidate gene for low phytate trait in soybean
3 Biotech
10
268
2020
Glycine max (I1JT87), Glycine max (U5TRK1), Glycine max
Looker, H.C.; Merchant, M.L.; Rane, M.J.; Nelson, R.G.; Kimmel, P.L.; Rovin, B.H.; Klein, J.B.; Mauer, M.; Mauer, M.
Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes
Am. J. Physiol. Renal Physiol.
315
F1484-F1492
2018
Homo sapiens (Q9H8X2), Homo sapiens
Whitfield, H.; White, G.; Sprigg, C.; Riley, A.M.; Potter, B.V.L.; Hemmings, A.M.; Brearley, C.A.
An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels
Biochem. J.
477
2621-2638
2020
Arabidopsis thaliana (Q93YN9)
Basak, N.; Krishnan, V.; Pandey, V.; Punjabi, M.; Hada, A.; Marathe, A.; Jolly, M.; Sachdev, A.
Molecular characterization of inositol pentakisphosphate 2-kinase (GmlPk1) from soybean and its expression pattern in the developing seeds
Indian J. Genet. Plant Breed.
77
371-378
2017
Glycine max (U5TRK1)
-
Franco-Echevarria, E.; Sanz-Aparicio, J.; Brearley, C.A.; Gonzalez-Rubio, J.M.; Gonzalez, B.
The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function
J. Biol. Chem.
292
10534-10548
2017
Mus musculus (Q6P1C1), Mus musculus
Whitfield, H.; Gilmartin, M.; Baker, K.; Riley, A.M.; Godage, H.Y.; Potter, B.V.L.; Hemmings, A.M.; Brearley, C.A.
A fluorescent probe identifies active site ligands of inositol pentakisphosphate 2-kinase
J. Med. Chem.
61
8838-8846
2018
Arabidopsis thaliana (Q93YN9)
Oh, J.; Lee, D.G.; Bahn, Y.S.; Rhee, S.
Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans
J. Struct. Biol.
200
118-123
2017
Cryptococcus neoformans var. grubii (J9VKS8), Cryptococcus neoformans var. grubii FGSC 9487 (J9VKS8), Cryptococcus neoformans var. grubii ATCC 208821 (J9VKS8), Cryptococcus neoformans var. grubii CBS 10515 (J9VKS8)
Kuo, H.; Hsu, Y.; Lin, W.; Chen, K.; Munnik, T.; Brearley, C.; Chiou, T.
Arabidopsis inositol phosphate kinases IPK1 and ITPK1 constitute a metabolic pathway in maintaining phosphate homeostasis
Plant J.
95
613-630
2018
Arabidopsis thaliana (Q93YN9), Arabidopsis thaliana
html completed
