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Disease on EC 2.7.1.11 - 6-phosphofructokinase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
1,4-alpha-glucan branching enzyme deficiency
[Polysaccharide amylopectin-type storage myopathy]
6-phosphofructokinase deficiency
A 5' splice junction mutation leading to exon deletion in an Ashkenazic Jewish family with phosphofructokinase deficiency (Tarui disease).
A genetic defect in muscle phosphofructokinase deficiency, a typical clinical entity presenting myogenic hyperuricemia.
A liver-type mutation in a case of pronounced erythrocyte phosphofructokinase deficiency without clinical expression.
A new type of phosphofructokinase deficiency hereditary nonspherocytic hemolytic anemia.
A new variant case of muscle phosphofructokinase deficiency, coexisting with gastric ulcer, gouty arthritis, and increased hemolysis.
A new variant of muscle phosphofructokinase deficiency in a Japanese case with abnormal RNA splicing.
Abnormal high-energy phosphate metabolism in human muscle phosphofructokinase deficiency.
Abnormal oxidative metabolism and O2 transport in muscle phosphofructokinase deficiency.
Activities of glycogen synthetase and UDPG-pyrophosphorylase in muscle of a patient with a new type of muscle glycogenosis caused by phosphofructokinase deficiency.
Acute renal failure in a patient with phosphofructokinase deficiency.
Age dependent behaviour of red cell glycolytic enzymes in haematological disorders.
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry.
Apparent absence of glycogen branching enzyme activity in phosphofructokinase deficiency.
Autosomal recessive inherited phosphofructokinase deficiency in English springer spaniel dogs.
Beneficial Effects of Ketogenic Diet on Phosphofructokinase Deficiency (Glycogen Storage Disease Type VII).
Biochemical characteristics of "young" and "old" erythrocytes of the newborn infant.
Biochemical studies of canine muscle phosphofructokinase deficiency.
Calcium in red blood cells-a perilous balance.
Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.
Characterization of the enzymatic lesion in inherited phosphofructokinase deficiency in the dog: an animal analogue of human glycogen storage disease type VII.
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Coexistence of diabetes and phosphofructokinase deficiency.
Congenital and metabolic myopathies of childhood or adult onset.
Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance.
Effect of fuels on exercise capacity in muscle phosphoglycerate mutase deficiency.
Enzymatic basis for the coexistence of myopathy and hemolytic disease in inherited muscle phosphofructokinase deficiency.
Erythrocyte phosphofructokinase deficiency associated with an unstable variant of muscle phosphofructokinase.
Familial phosphofructokinase deficiency is associated with a disturbed calcium homeostasis in erythrocytes.
Fatal familial infantile glycogen storage disease: multisystem phosphofructokinase deficiency.
Fatal infantile form of muscle phosphofructokinase deficiency.
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Free Mg2+ concentration in the calf muscle of glycogen phosphorylase and phosphofructokinase deficiency patients assessed in different metabolic conditions by 31P MRS.
Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).
Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.
Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII.
Genetic defect in muscle phosphofructokinase deficiency. Abnormal splicing of the muscle phosphofructokinase gene due to a point mutation at the 5'-splice site.
Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency.
Glycogen storage disease in skeletal muscle. Morphological, ultrastructural and biochemical aspects in 10 cases.
Glycogen storage disease: clinical, biochemical, and molecular heterogeneity.
Haemolytic anaemia and exercise intolerance due to phosphofructokinase deficiency in related springer spaniels.
Hemolysis caused by phosphofructokinase deficiency in English springer spaniels: seven cases (1983-1986).
Hemolysis, myopathy, and cardiac disease associated with hereditary phosphofructokinase deficiency in two Whippets.
Hereditary hemolytic anemia with erythrocyte phosphofructokinase deficiency: studies of some properties of erythrocyte and muscle enzyme.
Hereditary nonspherocytic hemolysis with erythrocyte phosphofructokinase deficiency.
Hereditary phosphofructokinase deficiency in wachtelhunds.
Heterogeneity of the molecular lesions in inherited phosphofructokinase deficiency.
Histochemical diagnosis of muscle phosphofructokinase deficiency.
Identification of three novel mutations in non-Ashkenazi Italian patients with muscle phosphofructokinase deficiency.
Impaired aerobic glycolysis in muscle phosphofructokinase deficiency results in biphasic post-exercise phosphocreatine recovery in 31P magnetic resonance spectroscopy.
Improvement of hemolysis in muscle phosphofructokinase deficiency by restriction of exercise.
In vivo determination of altered hemoglobin saturation in dogs with M-type phosphofructokinase deficiency.
In vivo lability of red cell phosphofructokinase in term infants: the possible molecular basis of the relative phosphofructokinase deficiency in neonatal red cells.
Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency.
Infantile form of muscle phosphofructokinase deficiency in a premature neonate.
Infantile phosphofructokinase deficiency with arthrogryposis: clinical benefit of a ketogenic diet.
Inherited erythrocyte phosphofructokinase deficiency: molecular mechanism.
Inherited phosphofructokinase deficiency associated with hemolysis and exertional myopathy.
Inherited phosphofructokinase deficiency in an American cocker spaniel.
Inherited phosphofructokinase deficiency in dogs with hyperventilation-induced hemolysis: increased in vitro and in vivo alkaline fragility of erythrocytes.
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency.
Kinetic properties of mutant enzymes in erythrocyte phosphofructokinase deficiency and erythrocyte pyruvate kinase deficiency.
Late-onset muscle phosphofructokinase deficiency.
Late-onset muscle weakness in partial phosphofructokinase deficiency: a unique myopathy with vacuoles, abnormal mitochondria, and absence of the common exon 5/intron 5 junction point mutation.
Late-onset muscular weakness in phosphofructokinase deficiency due to exon 5/intron 5 junction point mutation: a unique disorder or the natural course of this glycolytic disorder?
Letter: Red-cell phosphofructokinase deficiency.
Long-term survival and normal cognitive development in infantile phosphofructokinase-1 deficiency.
Magnetic resonance imaging of muscle injury and atrophy in glycolytic myopathies.
Metabolic myopathy in canine muscle-type phosphofructokinase deficiency.
Missense mutation in PFKM associated with muscle-type phosphofructokinase deficiency in the Wachtelhund dog.
Molecular basis of canine muscle type phosphofructokinase deficiency.
Muscle energy metabolism in human phosphofructokinase deficiency as recorded by 31P nuclear magnetic resonance spectroscopy.
Muscle metabolism during lactate infusion in human phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency (Tarui's disease).
Muscle phosphofructokinase deficiency (Tarui's disease): report of a case.
Muscle phosphofructokinase deficiency in a myopathic child with severe mental retardation and aplasia of cerebellar vermis.
Muscle phosphofructokinase deficiency in man: expression of the defect in blood cells and cultured fibroblasts.
Muscle phosphofructokinase deficiency in two generations.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Muscle phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency. Biochemical and immunological studies of phosphofructokinase isozymes in muscle culture.
Muscle phosphofructokinase deficiency: abnormal polysaccharide in a case of late-onset myopathy.
Muscle phosphofructokinase deficiency: two cases with unusual polysaccharide accumulation and immunologically active enzyme protein.
Mutations in muscle phosphofructokinase gene.
Myogenic hyperuricemia: what can we learn from metabolic myopathies?
Myopathies due to enzyme deficiencies.
Neurologic and cardiac progression of glycogenosis type VII over an eight-year period.
No spontaneous second wind in muscle phosphofructokinase deficiency.
Nonsense mutation in the phosphofructokinase muscle subunit gene associated with retention of intron 10 in one of the isolated transcripts in Ashkenazi Jewish patients with Tarui disease.
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
Paradoxically enhanced glucose production during exercise in humans with blocked glycolysis caused by muscle phosphofructokinase deficiency.
Partial block of glycolysis in late-onset phosphofructokinase deficiency myopathy.
Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis.
Phosphofructokinase deficiency (Tarui disease) associated with hepatic glucuronyltransferase deficiency (Gilbert's syndrome): a case and family study.
Phosphofructokinase Deficiency and Portal and Mesenteric Vein Thrombosis.
Phosphofructokinase deficiency associated with congenital nonspherocytic hemolytic anemia and mild myopathy: biochemical and morphological studies on the muscle.
Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells.
PHOSPHOFRUCTOKINASE DEFICIENCY IN SKELETAL MUSCLE. A NEW TYPE OF GLYCOGENOSIS.
Phosphofructokinase deficiency: recent advances in molecular biology.
Phosphofructokinase deficiency; past, present and future.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphorus magnetic resonance spectroscopy (31P MRS) in neuromuscular disorders.
Polysaccharide storage myopathy in canine phosphofructokinase deficiency (type VII glycogen storage disease).
Progress and problems in muscle glycogenoses.
Pyrophosphate-dependent phosphofructo-1-kinase complements fructose 1,6-bisphosphatase but not phosphofructokinase deficiency in Escherichia coli.
Reproducibility and absolute quantification of muscle glycogen in patients with glycogen storage disease by 13C NMR spectroscopy at 7 Tesla.
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies.
Tarui disease and distal glycogenoses: clinical and genetic update.
The contribution of Ca+ calmodulin activation of human erythrocyte AMP deaminase (isoform E) to the erythrocyte metabolic dysregulation of familial phosphofructokinase deficiency.
The contribution of Ca2+-calmodulin activation of human erythrocyte AMP deaminase (isoform E) to the erythrocyte metabolic dysregulation of familial phosphofructokinase deficiency.
The ketogenic diet: uses in epilepsy and other neurologic illnesses.
The molecular basis of muscle phosphofructokinase deficiency.
The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.
Two cases of phosphofructokinase deficiency associated with congenital hemolytic anemia found in Japan.
Unique Exercise Lactate Profile in Muscle Phosphofructokinase Deficiency (Tarui Disease); Difference Compared with McArdle Disease.
Various classes of mutations in patients with phosphofructokinase deficiency (Tarui's disease).
[Exercise-induced muscle pain due to phosphofrutokinase deficiency: Diagnostic contribution of metabolic explorations (exercise tests, 31P-nuclear magnetic resonance spectroscopy)].
[Exercise-induced muscular weakness, myalgia and contractures. I. A clinical review]
[Exercise-induced muscular weakness, myalgia and contractures. II. Casuistic contribution]
[Familial congenital muscular dystrophy caused by phosphofructokinase deficiency]
[Glycogen storage disease, type VII. Muscular phosphofructokinase deficiency]
[Muscular glycogenesis and haemolytic anaemia due to enzyme deficiency in two siblings. Familial form of Tarui's disease due to a deficiency in muscular and erythrocytic phosphofructokinase (author's transl)]
[Myopathic form of phosphofructokinase deficiency]
[Polysaccharide amylopectin-type storage myopathy]
Acidosis
Acidosis, phosphofructokinase, and diabetic coma.
Computer simulation of energy metabolism in acidotic cardiac ischemia.
Effects of regional ischemia on metabolism of glucose and fatty acids. Relative rates of aerobic and anaerobic energy production during myocardial infarction and comparison with effects of anoxia.
Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1.
Ischemic brain slice glucose utilization: effects of slice thickness, acidosis, and K+.
Metabolism of totally ischemic excised dog heart. II. Interpretation of a computer model.
Phosphofructokinase activity and acidosis during short-term tetanic contractions.
Reassessment of the cold-labile nature of phosphofructokinase from a hibernating ground squirrel.
Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies.
[Blood lactic acid level changes during acidosis induced by hydrochloric acid perfusion]
[Intermediates of erythrocyte glycolysis during three days hypercapnia in the dog (author's transl)]
Acidosis, Lactic
Neuroprotection conferred by post-ischemia ethanol therapy in experimental stroke: an inhibitory effect on hyperglycolysis and NADPH oxidase activation.
Acidosis, Renal Tubular
Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1.
Acidosis, Respiratory
Skeletal muscle lactate release and glycolytic intermediates during hypercapnia.
Acute Kidney Injury
Acute renal failure in a patient with phosphofructokinase deficiency.
[Activity of glycolysis key enzymes in subcellular structures of normal kidneys and under acute renal insufficiency]
Adenocarcinoma
Control of glycolysis by phosphofructokinase in slices of rat liver, Novikoff hepatoma, and adenocarcinomas.
Adenoma
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
Alkalosis
Post-hypercapnia recovery in the dog: arterial blood acid-base equilibrium and glycolysis.
Alphavirus Infections
Mayaro virus infection alters glucose metabolism in cultured cells through activation of the enzyme 6-phosphofructo 1-kinase.
Alzheimer Disease
Altered hexokinase activity in skin cultured fibroblasts and leukocytes from Alzheimer's disease patients.
Altered phosphofructokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease.
Changes of activity and isozyme pattern of phosphofructokinase in the brains of patients with Alzheimer's disease.
Phosphofructokinase activity in fibroblasts from patients with Alzheimer's disease and age- and sex-matched controls.
Phosphofructokinase activity in the brain in Alzheimer's disease.
amp deaminase deficiency
[Diagnostic significance of muscle biopsies in metabolic myopathies. II. Clinical biochemistry]
amylo-alpha-1,6-glucosidase deficiency
Myopathies due to enzyme deficiencies.
Anemia
Calcium in red blood cells-a perilous balance.
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Myocardial vascular and metabolic adaptations in chronically anemic fetal sheep.
Pathogenesis, laboratory diagnosis, and clinical implications of erythrocyte enzyme deficiencies in dogs, cats, and horses.
Anemia, Diamond-Blackfan
Enzymatic Changes in Red Blood Cells of Diamond-Blackfan Anemia.
Anemia, Hemolytic
A new type of phosphofructokinase deficiency hereditary nonspherocytic hemolytic anemia.
Characterization of phosphofructokinase-deficient canine erythrocytes.
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Erythrocyte phosphofructokinase deficiency associated with an unstable variant of muscle phosphofructokinase.
Haemolytic anaemia and exercise intolerance due to phosphofructokinase deficiency in related springer spaniels.
Hereditary phosphofructokinase deficiency in wachtelhunds.
Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency.
Missense mutation in PFKM associated with muscle-type phosphofructokinase deficiency in the Wachtelhund dog.
Muscle phosphofructokinase deficiency: two cases with unusual polysaccharide accumulation and immunologically active enzyme protein.
Phosphofructokinase deficiency associated with congenital nonspherocytic hemolytic anemia and mild myopathy: biochemical and morphological studies on the muscle.
Postnatal hematologic development in phosphofructokinase-deficient dogs.
Two cases of phosphofructokinase deficiency associated with congenital hemolytic anemia found in Japan.
[Muscular glycogenesis and haemolytic anaemia due to enzyme deficiency in two siblings. Familial form of Tarui's disease due to a deficiency in muscular and erythrocytic phosphofructokinase (author's transl)]
Anemia, Hemolytic, Congenital
Hereditary hemolytic anemia with erythrocyte phosphofructokinase deficiency: studies of some properties of erythrocyte and muscle enzyme.
Two cases of phosphofructokinase deficiency associated with congenital hemolytic anemia found in Japan.
Anemia, Hemolytic, Congenital Nonspherocytic
Phosphofructokinase deficiency associated with congenital nonspherocytic hemolytic anemia and mild myopathy: biochemical and morphological studies on the muscle.
Two cases of phosphofructokinase deficiency associated with congenital hemolytic anemia found in Japan.
Anemia, Refractory
Mechanisms of the acquired erythrocyte enzyme deficiencies in blood diseases.
Anemia, Sickle Cell
Calcium in red blood cells-a perilous balance.
Aneurysm
Salvia miltiorrhiza-Derived Sal-miR-58 Induces Autophagy and Attenuates Inflammation in Vascular Smooth Muscle Cells.
Arthritis, Gouty
A new variant case of muscle phosphofructokinase deficiency, coexisting with gastric ulcer, gouty arthritis, and increased hemolysis.
Muscle phosphofructokinase deficiency: two cases with unusual polysaccharide accumulation and immunologically active enzyme protein.
Arthritis, Rheumatoid
Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells.
Arthrogryposis
Infantile phosphofructokinase deficiency with arthrogryposis: clinical benefit of a ketogenic diet.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Atherosclerosis
Elevation of arterial phosphorfuctokinase activity associated with susceptibility to atherosclerosis in pigeons.
Brain Ischemia
[Glycolytic activity and fructose 2, 6-bisphosphate changes in rat brain during ischemia]
Breast Diseases
Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue.
Breast Neoplasms
Anti-mitochondrial therapy in human breast cancer multi-cellular spheroids.
Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer.
Differential expression of phosphofructokinase-1 isoforms correlates with the glycolytic efficiency of breast cancer cells.
Differential phosphofructokinase-1 isoenzyme patterns associated with glycolytic efficiency in human breast cancer and paracancer tissues.
Glycolytic enzyme activities in breast cancer metastases.
Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma.
Krüppel-like factor 4 (KLF4) activates the transcription of the gene for the platelet isoform of phosphofructokinase (PFKP) in breast cancer.
Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast.
Prognostic and therapeutic relevance of phosphofructokinase platelet-type (PFKP) in breast cancer.
Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
Tissue-Specific Warburg Effect in Breast Cancer and Cancer-Associated Adipose Tissue-Relationship between AMPK and Glycolysis.
Carcinogenesis
Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?
Role of PFKFB3 and CD163 in Oral Squamous Cell Carcinoma Angiogenesis.
Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis.
[Phosphofructokinase activity and glycolysis rate in the rat liver during carcinogenesis]
Carcinoma
A study of PKM2, PFK-1, and ANT1 expressions in cervical biopsy tissues in China.
Citrate induces apoptotic cell death: a promising way to treat gastric carcinoma?
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
Interaction of cytotoxic antibiotic dactylarin with glycolytic thiol enzymes in Ehrlich ascites carcinoma cells.
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
Phosphofructokinase type 1 kinetics, isoform expression and gene polymorphisms in cancer cells.
Phosphofructokinase-M inhibits cell growth via modulating the FOXO3 pathway in renal cell carcinoma cells.
Prognostic Roles of Phosphofructokinase Platelet in Clear Cell Renal Cell Carcinoma and Correlation with Immune Infiltration.
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Carcinoma, Ehrlich Tumor
Fructose 2,6-bisphosphate metabolism in Ehrlich ascites tumour cells.
Kinetic studies on phosphofructokinase from Ehrlich ascites tumor cells.
Phosphofructokinase from Ehrlich ascites tumor.
Purification and some properties of phosphofructokinase from Ehrlich ascites tumor cells.
The effect of magnesium on glycolysis of permeabilized Ehrlich ascites tumor cells.
The effect of Mg2+ upon 6-phosphofructokinase activity in Ehrlich ascites tumor cells in vivo.
Carcinoma, Embryonal
Phosphofructokinase and pyruvate kinase in mouse embryonal carcinoma P19 cells in relation to growth and differentiation.
Carcinoma, Hepatocellular
A comparative study of rat liver, muscle, and hepatoma 3924A phosphofructokinase isozymes.
A comparison of the phosphofructokinase isoenzyme profiles of transplantable hepatomas and normal liver.
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase.
In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity.
Increased phosphofructokinase concentration in hepatoma 3924-A: enzymic and immunological evidence.
Phosphofructokinase isozymes of Morris hepatomas.
Regulation of rat liver phosphofructokinase levels in Morris hepatomas.
Synthesis and degradation of the major hepatic phosphofructokinase isozyme in rat liver and hepatoma 3924-A.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
Carcinoma, Lewis Lung
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
Carcinoma, Papillary
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
Carcinoma, Renal Cell
Phosphofructokinase-M inhibits cell growth via modulating the FOXO3 pathway in renal cell carcinoma cells.
Prognostic Roles of Phosphofructokinase Platelet in Clear Cell Renal Cell Carcinoma and Correlation with Immune Infiltration.
The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma.
Cardiomegaly
Function of myocardial alpha-adrenoceptors.
Cardiomyopathies
Glycolysis in heart failure: a 31P-NMR and surface fluorometry study.
Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of Reiske iron-sulfur protein, ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes.
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
carnitine o-palmitoyltransferase deficiency
Abnormal oxidative metabolism and O2 transport in muscle phosphofructokinase deficiency.
Neonatal metabolic myopathies.
Cleft Palate
Infantile form of muscle phosphofructokinase deficiency in a premature neonate.
coagulation factor viia deficiency
Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).
Colonic Neoplasms
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
The activity of phosphofructokinase and lactate dehydrogenase in cancer of the colon and rectum and the effect of iodine on the normal mucosa.
Colorectal Neoplasms
SiRNA targeting PFK1 inhibits proliferation and migration and enhances radiosensitivity by suppressing glycolysis in colorectal cancer.
Coma
Effect of total hepatectomy on selected cerebral substrates and enzymes of the glycolytic pathways and Krebs cycle.
Contracture
Infantile form of muscle phosphofructokinase deficiency in a premature neonate.
Muscle phosphofructokinase deficiency in a myopathic child with severe mental retardation and aplasia of cerebellar vermis.
Cryptorchidism
Phosphofructokinase in the rat testis: changes in isozyme patterns during maturation and short term cryptorchidism.
Cystic Fibrosis
Increased activity of four glycolytic enzymes in cultured fibroblasts from cystic fibrosis patients.
Cystinuria
Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).
Cytochrome-c Oxidase Deficiency
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry.
Neonatal metabolic myopathies.
Dehydration
Increased Drying Rate Lowers the Critical Water Content for Survival in Embryonic Axes of English Oak (Quercus robur L.) Seeds.
Dementia
Glycolytic enzymes from human autoptic brain cortex: normal aged and demented cases.
Phosphofructokinase activity in the brain in Alzheimer's disease.
Dengue
Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster.
Diabetes Mellitus
Coexistence of diabetes and phosphofructokinase deficiency.
Impaired 6-phosphofructokinase activity in mononuclear leukocytes from patients with type II diabetes mellitus.
Myocardial dysfunction in diabetic rats: influence of beta-adrenoceptor blockade (propranolol).
[Mutation/polymorphism of phosphofructokinase (PFK) genes in diabetes mellitus]
Diabetes Mellitus, Experimental
Effects of alloxan diabetes, starvation and hypophysectomy on total phosphofructokinase activity in rat heart.
Effects of long-term streptozotocin diabetes on cytoskeletal and cytosolic phosphofructokinase and the levels of glucose 1,6-bisphosphate and fructose 2,6-bisphosphate in different rat muscles.
THE REGULATION OF HEXOKINASE AND PHOSPHOFRUCTOKINASE ACTIVITY IN HEART MUSCLE. EFFECTS OF ALLOXAN DIABETES, GROWTH HORMONE, CORTISOL, AND ANOXIA.
Diabetes Mellitus, Type 1
Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids
Diabetes Mellitus, Type 2
Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance.
Experimental type 2 diabetes induces enzymatic changes in isolated rat enterocytes.
Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.
Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): reassignment to human chromosome 12q.
Type 2 diabetes differentially affects the substrate saturation kinetic attributes of erythrocyte hexokinase and phosphofructokinase.
Diabetic Coma
Acidosis, phosphofructokinase, and diabetic coma.
Down Syndrome
Altered brain glucose metabolism in transgenic-PFKL mice with elevated L-phosphofructokinase: in vivo NMR studies.
Blood cell phosphofructokinase in Down's syndrome.
Erythrocyte ATP: D-fructose-6-phosphate 1-phosphotransferase (phosphofructokinase) activity in children with normałG trisomic mosaic Down's syndrome and in normal and Down's syndrome controls.
Gene dosage and Down's syndrome: metabolic and enzymatic changes in PC12 cells overexpressing transfected human liver-type phosphofructokinase.
Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21.
Phosphofructokinase activity in fibroblasts aneuploid for chromosome 21.
PHOSPHOHEXOKINASE ACTIVITY OF ERYTHROCYTES IN MONGOLISM: ANOTHER POSSIBLE MARKER FOR CHROMOSOME 21.
Protein kinase C (PKC) level is increased in PC12 cells overexpressing transfected liver-type phosphofructokinase.
Superoxide dismutase and glutathione peroxidase abnormalities in erythrocytes and lymphoid cells in Down syndrome.
[Phosphofructokinase (PFK)]
[Rapid prenatal detection of Down syndrome by homologous gene quantitative PCR]
Erythema
Effects of whole body UV-irradiation on oxygen delivery from the erythrocyte.
Factor VII Deficiency
Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).
Fatty Liver
Biotin deficiency and susceptibility to fatty liver and kidney syndrome in broiler chicks: reduced 6-phosphofructokinase (EC 2.7.1.11) activity but normal fructose 2,6-bisphosphate content in birds with hepatomegaly.
Favism
[New acquisitions on the subject of the bio-enzymology of ictero-hemoglobinuric favism. Note I. The enolase, fructokinase and phosphofructokinase activity of the erythrocytes.]
Filariasis
Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster.
Glioblastoma
Phosphofructokinase 1 Platelet Isoform Promotes ?-Catenin Transactivation for Tumor Development.
Glioma
Activities of glycolytic enzymes in rapidly proliferating and differentiated C6 glioma cells.
Enzymes of glucose metabolism in cultured human gliomas: neoplasia is accompanied by altered hexokinase, phosphofructokinase, and glucose-6-phosphate dehydrogenase levels.
Enzymes related to energy metabolism in human gliomas.
Phosphorylation of pyruvate kinase and glycolytic metabolism in three human glioma cell lines.
Subunit composition, regulatory properties, and phosphorylation of phosphofructokinase from human gliomas.
glucan 1,4-alpha-glucosidase deficiency
Congenital and metabolic myopathies of childhood or adult onset.
glucuronosyltransferase deficiency
Phosphofructokinase deficiency (Tarui disease) associated with hepatic glucuronyltransferase deficiency (Gilbert's syndrome): a case and family study.
glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency
A simple screening procedure for glucose phosphate isomerase, phosphofructokinase, aldolase and glyceraldehyde-3-phosphate dehydrogenase deficiencies.
glycogen phosphorylase deficiency
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry.
Congenital and metabolic myopathies of childhood or adult onset.
Effect of fuels on exercise capacity in muscle phosphoglycerate mutase deficiency.
Free Mg2+ concentration in the calf muscle of glycogen phosphorylase and phosphofructokinase deficiency patients assessed in different metabolic conditions by 31P MRS.
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Magnetic resonance imaging of muscle injury and atrophy in glycolytic myopathies.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphorus magnetic resonance spectroscopy (31P MRS) in neuromuscular disorders.
Glycogen Storage Disease
Activities of glycogen synthetase and UDPG-pyrophosphorylase in muscle of a patient with a new type of muscle glycogenosis caused by phosphofructokinase deficiency.
Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.
Characterization of the enzymatic lesion in inherited phosphofructokinase deficiency in the dog: an animal analogue of human glycogen storage disease type VII.
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance.
Developmental changes of 6-phosphofructo-1-kinase subunit levels in erythrocytes from normal dogs and dogs affected by glycogen storage disease type VII.
Erythrocyte glycolysis and its marked alterations by muscular exercise in type VII glycogenosis.
Exercise-induced muscle modifications: study of healthy subjects and patients with metabolic myopathies with MR imaging and P-31 spectroscopy.
Fatal familial infantile glycogen storage disease: multisystem phosphofructokinase deficiency.
Fatal infantile glycogen storage disease: deficiency of phosphofructokinase and phosphorylase b kinase.
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Genetic defect in muscle phosphofructokinase deficiency. Abnormal splicing of the muscle phosphofructokinase gene due to a point mutation at the 5'-splice site.
Glycogenosis type VII (Tarui disease) in a Swedish family: two novel mutations in muscle phosphofructokinase gene (PFK-M) resulting in intron retentions.
Hereditary and acquired abnormalities in erythrocyte phosphofructokinase activity: the close association with altered 2,3-diphosphoglycerate levels.
Imbalance of plasma membrane ion leak and pump relationship as a new aetiological basis of certain disease states.
Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency.
Insulin resistance and impaired insulin secretion due to phosphofructo-1-kinase-deficiency in humans.
Kinetic properties of erythrocyte phosphofructokinase in patients with type VII glycogenosis from two families--close similarity to liver type phosphofructokinase.
Late and Severe Myopathy in a Patient With Glycogenosis VII Worsened by Cyclosporine and Amiodarone.
Low glucose-1, 6-bisphosphate and high fructose-2, 6-bisphosphate concentrations in muscles of patients with glycogenosis types VII and V.
Metabolic myopathies.
Molecular basis of canine muscle type phosphofructokinase deficiency.
Myogenic hyperuricemia. A common pathophysiologic feature of glycogenosis types III, V, and VII.
Neonatal metabolic myopathies.
Nonsense mutation in the phosphofructokinase muscle subunit gene associated with retention of intron 10 in one of the isolated transcripts in Ashkenazi Jewish patients with Tarui disease.
Novel missense mutation (W686C) of the phosphofructokinase-M gene in a Japanese patient with a mild form of glycogenosis VII.
Pathophysiology of impaired pulsatile insulin release.
Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis.
PHOSPHOFRUCTOKINASE DEFICIENCY IN SKELETAL MUSCLE. A NEW TYPE OF GLYCOGENOSIS.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Presence of a truncated M-type subunit and altered kinetic properties of 6-phosphofructo-1-kinase isozymes in the brain of a dog affected by glycogen storage disease type VII.
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
Tarui disease and distal glycogenoses: clinical and genetic update.
The ketogenic diet: uses in epilepsy and other neurologic illnesses.
Type VII glycogenosis (muscle and erythrocyte phosphofructokinase deficiency).
[A case of glycogen storage myopathy with acute heart failure]
[Exercise-induced muscle pain due to phosphofrutokinase deficiency: Diagnostic contribution of metabolic explorations (exercise tests, 31P-nuclear magnetic resonance spectroscopy)].
[Glycogen storage disease, type VII. Muscular phosphofructokinase deficiency]
Glycogen Storage Disease Type II
Congenital and metabolic myopathies of childhood or adult onset.
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
Glycogen Storage Disease Type IIb
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
Glycogen Storage Disease Type V
An oxidative defect in metabolic myopathies: diagnosis by noninvasive tissue oximetry.
Congenital and metabolic myopathies of childhood or adult onset.
Effect of fuels on exercise capacity in muscle phosphoglycerate mutase deficiency.
Exercise-induced muscle modifications: study of healthy subjects and patients with metabolic myopathies with MR imaging and P-31 spectroscopy.
Free Mg2+ concentration in the calf muscle of glycogen phosphorylase and phosphofructokinase deficiency patients assessed in different metabolic conditions by 31P MRS.
Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII.
Iodoacetate inhibition of glyceraldehyde-3-phosphate dehydrogenase as a model of human myophosphorylase deficiency (McArdle's disease) and phosphofructokinase deficiency (Tarui's disease).
Magnetic resonance imaging of muscle injury and atrophy in glycolytic myopathies.
No spontaneous second wind in muscle phosphofructokinase deficiency.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Phosphorus magnetic resonance spectroscopy (31P MRS) in neuromuscular disorders.
Reproducibility and absolute quantification of muscle glycogen in patients with glycogen storage disease by 13C NMR spectroscopy at 7 Tesla.
Unique Exercise Lactate Profile in Muscle Phosphofructokinase Deficiency (Tarui Disease); Difference Compared with McArdle Disease.
[McArdle's disease: a case report]
Glycogen Storage Disease Type VII
A genetic defect in muscle phosphofructokinase deficiency, a typical clinical entity presenting myogenic hyperuricemia.
A new variant case of muscle phosphofructokinase deficiency, coexisting with gastric ulcer, gouty arthritis, and increased hemolysis.
A new variant of muscle phosphofructokinase deficiency in a Japanese case with abnormal RNA splicing.
Abnormal high-energy phosphate metabolism in human muscle phosphofructokinase deficiency.
Abnormal oxidative metabolism and O2 transport in muscle phosphofructokinase deficiency.
Altered allosteric regulation of muscle 6-phosphofructokinase causes Tarui disease.
Apparent absence of glycogen branching enzyme activity in phosphofructokinase deficiency.
Beneficial Effects of Ketogenic Diet on Phosphofructokinase Deficiency (Glycogen Storage Disease Type VII).
Biochemical studies of canine muscle phosphofructokinase deficiency.
Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.
Characterization of the enzymatic lesion in inherited phosphofructokinase deficiency in the dog: an animal analogue of human glycogen storage disease type VII.
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance.
Developmental changes of 6-phosphofructo-1-kinase subunit levels in erythrocytes from normal dogs and dogs affected by glycogen storage disease type VII.
Enzymatic basis for the coexistence of myopathy and hemolytic disease in inherited muscle phosphofructokinase deficiency.
Familial phosphofructokinase deficiency is associated with a disturbed calcium homeostasis in erythrocytes.
Fatal infantile form of muscle phosphofructokinase deficiency.
Free Mg2+ concentration in the calf muscle of glycogen phosphorylase and phosphofructokinase deficiency patients assessed in different metabolic conditions by 31P MRS.
Genetic defect in muscle phosphofructokinase deficiency. Abnormal splicing of the muscle phosphofructokinase gene due to a point mutation at the 5'-splice site.
Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency.
Histochemical diagnosis of muscle phosphofructokinase deficiency.
Identification of three novel mutations in non-Ashkenazi Italian patients with muscle phosphofructokinase deficiency.
Imbalance of plasma membrane ion leak and pump relationship as a new aetiological basis of certain disease states.
Impaired aerobic glycolysis in muscle phosphofructokinase deficiency results in biphasic post-exercise phosphocreatine recovery in 31P magnetic resonance spectroscopy.
Improvement of hemolysis in muscle phosphofructokinase deficiency by restriction of exercise.
Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency.
Infantile form of muscle phosphofructokinase deficiency in a premature neonate.
Insulin resistance and impaired insulin secretion due to phosphofructo-1-kinase-deficiency in humans.
Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency.
Late-onset muscle phosphofructokinase deficiency.
Magnetic resonance imaging of muscle injury and atrophy in glycolytic myopathies.
Muscle phosphofructokinase deficiency (Tarui's disease).
Muscle phosphofructokinase deficiency (Tarui's disease): report of a case.
Muscle phosphofructokinase deficiency in a myopathic child with severe mental retardation and aplasia of cerebellar vermis.
Muscle phosphofructokinase deficiency in man: expression of the defect in blood cells and cultured fibroblasts.
Muscle phosphofructokinase deficiency in two generations.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Muscle phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency. Biochemical and immunological studies of phosphofructokinase isozymes in muscle culture.
Muscle phosphofructokinase deficiency: abnormal polysaccharide in a case of late-onset myopathy.
Muscle phosphofructokinase deficiency: two cases with unusual polysaccharide accumulation and immunologically active enzyme protein.
Myogenic hyperuricemia: what can we learn from metabolic myopathies?
No spontaneous second wind in muscle phosphofructokinase deficiency.
Nonsense mutation in the phosphofructokinase muscle subunit gene associated with retention of intron 10 in one of the isolated transcripts in Ashkenazi Jewish patients with Tarui disease.
Paradoxically enhanced glucose production during exercise in humans with blocked glycolysis caused by muscle phosphofructokinase deficiency.
Phosphofructokinase deficiency (Tarui disease) associated with hepatic glucuronyltransferase deficiency (Gilbert's syndrome): a case and family study.
Phosphofructokinase deficiency; past, present and future.
Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms.
Physical and genetic mapping of the muscle phosphofructokinase gene (PFKM): reassignment to human chromosome 12q.
Presence of a truncated M-type subunit and altered kinetic properties of 6-phosphofructo-1-kinase isozymes in the brain of a dog affected by glycogen storage disease type VII.
Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies.
The molecular basis of muscle phosphofructokinase deficiency.
Unique Exercise Lactate Profile in Muscle Phosphofructokinase Deficiency (Tarui Disease); Difference Compared with McArdle Disease.
[Exercise-induced muscle pain due to phosphofrutokinase deficiency: Diagnostic contribution of metabolic explorations (exercise tests, 31P-nuclear magnetic resonance spectroscopy)].
[Glycogen storage disease, type VII. Muscular phosphofructokinase deficiency]
[Muscular glycogenesis and haemolytic anaemia due to enzyme deficiency in two siblings. Familial form of Tarui's disease due to a deficiency in muscular and erythrocytic phosphofructokinase (author's transl)]
Heart Arrest
Effects of fructose-1,6-diphosphate, glucose, and saline on cardiac resuscitation.
Oxidative stress reversibly inactivates myocardial enzymes during cardiac arrest.
Heart Diseases
Hemolysis, myopathy, and cardiac disease associated with hereditary phosphofructokinase deficiency in two Whippets.
Heart Failure
Skeletal muscle depressed calcium and phosphofructokinase in chronic heart failure are upregulated by captopril--a double-blind, placebo-controlled study.
Skeletal muscle lactate accumulation and creatine phosphate depletion during heavy exercise in congestive heart failure. Cause of limited exercise capacity?
Hemangioma
Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma.
Hepatitis
Undifferentiated patterns of key carbohydrate-metabolizing enzymes in injured livers. II. Human viral hepatitis and cirrhosis of the liver.
Hepatomegaly
Biotin deficiency and susceptibility to fatty liver and kidney syndrome in broiler chicks: reduced 6-phosphofructokinase (EC 2.7.1.11) activity but normal fructose 2,6-bisphosphate content in birds with hepatomegaly.
Herpes Simplex
Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).
Hookworm Infections
Biochemical and histopathological alterations in golden hamster during infection with Ancylostoma ceylanicum.
Hyperglycemia
Anabolic response of some tissues to diabetes.
Experimental type 2 diabetes induces enzymatic changes in isolated rat enterocytes.
Metformin counteracts glucose-dependent lipogenesis and impairs transdeamination in the liver of gilthead sea bream (Sparus aurata).
Mouse (C57BL/KsJ) liver phosphofructokinase. Allosteric kinetics and age-related changes in the genetically diabetic state.
Hyperparathyroidism, Primary
Severe Cardiomyopathy as the Isolated Presenting Feature in an Adult with Late-Onset Pompe Disease: A Case Report.
Hypersensitivity
Fatty acid-induced beta cell hypersensitivity to glucose. Increased phosphofructokinase activity and lowered glucose-6-phosphate content.
Hyperthyroidism
Effect of thyroid hormones on the glycolytic enzyme activity in brain areas of the rat.
Effect of thyroid status on the expression of metabolic enzymes during chronic stimulation.
Effects of hyperthyroidism on glucose, glutamine and ketone-body metabolism in the gut of the rat.
Hyperthyroidism results in increased glycolytic capacity in the rat heart. A 31P-NMR study.
Specific effect of thyroid hormone on testicular enzymes involved in carbohydrate metabolism. II. Hyperthyroidism.
The rate of substrate cycling between fructose 6-phosphate and fructose 1,6-bisphosphate in skeletal muscle from cold-exposed, hyperthyroid or acutely exercised rats.
Hypervitaminosis A
Early effects of vitamin A toxicity on hepatic glycolysis in rat.
Hypoglycemia
Carbohydrate metabolism in temporal and persistent hypoglycemic chickens induced by insulin infusion.
Changes in muscle mRNAs for hexokinase, phosphofructokinase-1 and glycogen synthase in acute and persistent hypoglycemia induced by tolbutamide in chickens.
Effect of insulin-induced hypoglycemia on cytoskeleton-bound and cytosolic phosphofructokinase and the levels of glucose 1,6-bisphosphate in rat brain.
Starvation and seizures. Observation on the electroconvulsive threshold and cerebral metabolism of the starved adult rat.
Hypothyroidism
A tissue-specific increase in lipogenesis in rat brown adipose tissue in hypothyroidism.
Effect of experimental hypothyroidism on the control of 6-phosphofructo-1-kinase activity in rat jejunal mucosa.
The effect of experimental hypothyroidism on phosphofructokinase activity and fructose 2,6-bisphosphate concentrations in rat heart.
Hypoxia, Brain
Cerebral carbohydrate metabolism during acute carbon monoxide intoxication.
Infarction, Middle Cerebral Artery
Phosphofructokinase-1 Inhibition Promotes Neuronal Differentiation of Neural Stem Cells and Functional Recovery After Stroke.
Infections
A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication.
Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1? by Restriction of PFK-M via MicroRNA-21.
Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection.
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
Insulin Resistance
Different types of postinsulin receptor defects contribute to insulin resistance in hearts of obese Zucker rats.
Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.
Impaired 6-phosphofructokinase activity in mononuclear leukocytes from patients with type II diabetes mellitus.
Kinetics of phosphofructokinase from granulocytes isolated from patients with insulin resistance.
Linkage analysis of 19 candidate regions for insulin resistance in familial NIDDM.
Molecular and Metabolic Markers of Fructose Induced Hepatic Insulin Resistance in Developing and Adult Rats are Distinct and Aegle marmelos is an Effective Modulator.
Intellectual Disability
Muscle phosphofructokinase deficiency in a myopathic child with severe mental retardation and aplasia of cerebellar vermis.
Intermittent Claudication
Muscle enzyme adaptation in patients with peripheral arterial insufficiency: spontaneous adaptation, effect of different treatments and consequences on walking performance.
Intracranial Embolism
Naftidrofuryl oxalate improves impaired brain glucose metabolism after microsphere-induced cerebral embolism in rats.
Ketosis
Alteration of glycolytic intermediary metabolism in erythrocytes during diabetic ketoacidosis and its recovery phase.
Starvation and seizures. Observation on the electroconvulsive threshold and cerebral metabolism of the starved adult rat.
Kidney Failure, Chronic
Energy production, intracellular amino acid pools, and protein synthesis in chronic renal disease.
Klatskin Tumor
PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma.
Leiomyoma
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Compensatory alterations in energy homeostasis characterized in uterine tumors from hereditary leiomyomatosis and renal cell cancer.
Leiomyosarcoma
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Leukemia
Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator.
Erythrocyte phosphofructokinase and glucose-6-phosphate dehydrogenase in leukemia.
Phosphofructokinase activity of blood cells in leukemia.
Leukemia, Erythroblastic, Acute
Mechanisms of the acquired erythrocyte enzyme deficiencies in blood diseases.
Leukemia, Lymphocytic, Chronic, B-Cell
Isozyme distribution of hexokinase, phosphofructokinase and pyruvate kinase in lymphocytes from patients with chronic lymphocytic leukemia.
Phosphofructokinase in human blood cells.
Leukemia, Lymphoid
Antitumor agents. XXXV: Effects of brusatol, bruceoside A, and bruceantin on P-388 lymphocytic leukemia cell respiration.
Control of phosphofructokinase by fructose 2,6-bisphosphate in B-lymphocytes and B-chronic lymphocytic leukemia cells.
Research progress on neurobiology of neuronal nitric oxide synthase.
Leukemia, Myeloid, Acute
Mechanisms of the acquired erythrocyte enzyme deficiencies in blood diseases.
Leukemia, Promyelocytic, Acute
Bezafibrate induces a mitochondrial derangement in human cell lines: a PPAR-independent mechanism for a peroxisome proliferator.
Lipomatosis
Molecular biology of metabolic disease: defects in the regulation of enzymic activity.
Liver Neoplasms, Experimental
Control of glycolysis by phosphofructokinase in slices of rat liver, Novikoff hepatoma, and adenocarcinomas.
Lung Neoplasms
Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems.
Platelet isoform of phosphofructokinase promotes aerobic glycolysis and the progression of non?small cell lung cancer.
Lymphatic Metastasis
[Expression of phosphofructokinase 1 protein and it's enzyme activity on nasopharyngeal carcinoma].
Malaria
Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster.
Malnutrition
Effect of protein malnutrition on the glycolytic and glutaminolytic enzyme activity of rat thymus and mesenteric lymph nodes.
Feeding a low energy diet and refeeding a control diet affect glycolysis differently in the slow- and fast-twitch muscles of adult male Wistar rats.
Mania
Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose-1,6-diphosphate levels in rat muscles, brain and liver.
Mastocytoma
Regulation of pyruvate kinase expression and growth in mastocytoma cells. I. Initial observations.
Melanoma
Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics.
Expression of Alternative Splice Variants of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase-4 in Normoxic and Hypoxic Melanoma Cells.
Metabolic characterization of three hamster melanoma variants.
Taxol (paclitaxel) induces a detachment of phosphofructokinase from cytoskeleton of melanoma cells and decreases the levels of glucose 1,6-bisphosphate, fructose 1,6-bisphosphate and ATP.
Melanoma, Amelanotic
Metabolic characterization of three hamster melanoma variants.
Melanoma, Experimental
Detachment of glycolytic enzymes from cytoskeleton of melanoma cells induced by calmodulin antagonists.
Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics.
Taxol (paclitaxel) induces a detachment of phosphofructokinase from cytoskeleton of melanoma cells and decreases the levels of glucose 1,6-bisphosphate, fructose 1,6-bisphosphate and ATP.
Meningioma
Metabolic patterns in meningiomas.
Mesothelioma
Effect of citrate on malignant pleural mesothelioma cells: a synergistic effect with cisplatin.
Metabolism, Inborn Errors
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Identification of a canine model of pyruvate dehydrogenase phosphatase 1 deficiency.
Mitochondrial Diseases
Myogenic hyperuricemia: what can we learn from metabolic myopathies?
The role of muscle biopsy in investigating isolated muscle pain.
Mitochondrial Myopathies
Metabolic myopathies.
Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies.
Muscle Cramp
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Improvement of hemolysis in muscle phosphofructokinase deficiency by restriction of exercise.
Metabolic myopathy in canine muscle-type phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Muscle phosphofructokinase deficiency: abnormal polysaccharide in a case of late-onset myopathy.
Muscle Hypotonia
Neonatal metabolic myopathies.
Muscle Weakness
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency.
Late-onset muscle weakness in partial phosphofructokinase deficiency: a unique myopathy with vacuoles, abnormal mitochondria, and absence of the common exon 5/intron 5 junction point mutation.
Late-onset muscular weakness in phosphofructokinase deficiency due to exon 5/intron 5 junction point mutation: a unique disorder or the natural course of this glycolytic disorder?
Myopathies due to enzyme deficiencies.
Phosphofructokinase deficiency: recent advances in molecular biology.
[Phosphofructokinase (PFK)]
Muscular Diseases
A 5' splice junction mutation leading to exon deletion in an Ashkenazic Jewish family with phosphofructokinase deficiency (Tarui disease).
Congenital and metabolic myopathies of childhood or adult onset.
Enzymatic basis for the coexistence of myopathy and hemolytic disease in inherited muscle phosphofructokinase deficiency.
Haemolytic anaemia and exercise intolerance due to phosphofructokinase deficiency in related springer spaniels.
Hemolysis, myopathy, and cardiac disease associated with hereditary phosphofructokinase deficiency in two Whippets.
In vivo determination of altered hemoglobin saturation in dogs with M-type phosphofructokinase deficiency.
Infantile phosphofructokinase deficiency with arthrogryposis: clinical benefit of a ketogenic diet.
Influenza and myoglobinuria in brothers.
Inherited phosphofructokinase deficiency associated with hemolysis and exertional myopathy.
Late-onset muscle weakness in partial phosphofructokinase deficiency: a unique myopathy with vacuoles, abnormal mitochondria, and absence of the common exon 5/intron 5 junction point mutation.
Late-onset muscular weakness in phosphofructokinase deficiency due to exon 5/intron 5 junction point mutation: a unique disorder or the natural course of this glycolytic disorder?
Metabolic myopathy in canine muscle-type phosphofructokinase deficiency.
Missense mutation in PFKM associated with muscle-type phosphofructokinase deficiency in the Wachtelhund dog.
Molecular basis of canine muscle type phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency in a myopathic child with severe mental retardation and aplasia of cerebellar vermis.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Muscle phosphofructokinase deficiency: abnormal polysaccharide in a case of late-onset myopathy.
Mutations in muscle phosphofructokinase gene.
Nonsense mutation in the phosphofructokinase muscle subunit gene associated with retention of intron 10 in one of the isolated transcripts in Ashkenazi Jewish patients with Tarui disease.
Other erythrocyte enzyme deficiencies associated with non-haematological symptoms: phosphoglycerate kinase and phosphofructokinase deficiency.
Partial block of glycolysis in late-onset phosphofructokinase deficiency myopathy.
Phosphofructokinase deficiency (Tarui disease) associated with hepatic glucuronyltransferase deficiency (Gilbert's syndrome): a case and family study.
Phosphofructokinase deficiency associated with congenital nonspherocytic hemolytic anemia and mild myopathy: biochemical and morphological studies on the muscle.
Polysaccharide storage myopathy in canine phosphofructokinase deficiency (type VII glycogen storage disease).
Skeletal muscle glycolytic capacity and phosphofructokinase regulation in horses with polysaccharide storage myopathy.
The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.
The role of muscle biopsy in investigating isolated muscle pain.
Two cases of phosphofructokinase deficiency associated with congenital hemolytic anemia found in Japan.
[Polysaccharide amylopectin-type storage myopathy]
Muscular Dystrophies
Altered allosteric properties of cytoskeleton-bound phosphofructokinase in muscle from mice with X chromosome-linked muscular dystrophy (mdx).
Loss of positive allosteric interactions between neuronal nitric oxide synthase and phosphofructokinase contributes to defects in glycolysis and increased fatigability in muscular dystrophy.
[Familial congenital muscular dystrophy caused by phosphofructokinase deficiency]
Myalgia
Beneficial Effects of Ketogenic Diet on Phosphofructokinase Deficiency (Glycogen Storage Disease Type VII).
Myocardial Ischemia
Action of anti-anginal drugs on cardiac metabolism.
Effects of MCI-176, a new quinazolinone calcium antagonist, on myocardial energy and carbohydrate metabolism in ischemic dog hearts.
The rapid and reversible association of phosphofructokinase with myocardial membranes during myocardial ischemia.
[Effects of betaxolol, a cardioselective beta-adrenoceptor antagonist, on ischemic myocardial energy and carbohydrate metabolism in dogs]
Myoglobinuria
Clinical features and new molecular findings in muscle phosphofructokinase deficiency (GSD type VII).
Coexistence of diabetes and phosphofructokinase deficiency.
Combined defects of muscle phosphofructokinase and AMP deaminase in a child with myoglobinuria.
Influenza and myoglobinuria in brothers.
Metabolic causes of myoglobinuria.
Metabolic myopathies.
Metabolic myopathy in canine muscle-type phosphofructokinase deficiency.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Muscle phosphofructokinase deficiency: abnormal polysaccharide in a case of late-onset myopathy.
Neonatal metabolic myopathies.
Various classes of mutations in patients with phosphofructokinase deficiency (Tarui's disease).
[Clinical demonstrations of hereditary disorders of metabolism]
[McArdle's disease: a case report]
[Myoglobinuria due to enzyme abnormalities in glycolytic pathway--especially lactate dehydrogenase M subunit deficiency]
Myoma
Some properties of human uterine myoma phosphofructokinase.
Myopathies, Nemaline
Congenital and metabolic myopathies of childhood or adult onset.
Myopathy, Central Core
The role of muscle biopsy in investigating isolated muscle pain.
Myotonia Congenita
Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).
Nasopharyngeal Carcinoma
[Expression and clinical significance of 6-phosphofructo-1-kinase in nasopharyngeal carcinoma].
[Expression of phosphofructokinase 1 protein and it's enzyme activity on nasopharyngeal carcinoma].
Nematode Infections
Molecular and biochemical characterisation of abomasal nematode parasites Teladorsagia circumcincta and Haemonchus contortus phosphofructokinases and their recognition by the immune host.
Neoplasm Metastasis
Glycolytic enzyme activities in breast cancer metastases.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
[Expression of phosphofructokinase 1 protein and it's enzyme activity on nasopharyngeal carcinoma].
Neoplasms
3PO inhibits inflammatory NF?B and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3.
A new cancer marker: a possible cancer screening method based on the suppression of phosphofructokinase by sera from cancer patients.
Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity.
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in lipoblastic and neurogenic proliferations.
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Aegle marmelos differentially affects hepatic markers of glycolysis, insulin signalling pathway, hypoxia, and inflammation in HepG2 cells grown in fructose versus glucose-rich environment.
All in for nuclear PFKP-induced CXCR4 metastasis: a T cell acute lymphoblastic leukemia prognostic marker.
Alterations in erythrocyte enzymes in cancer.
Alterations in the activity and isozymic profile of human phosphofructokinase during malignant transformation in vivo and in vitro: transformation- and progression-linked discriminants of malignancy.
Analysis of phosphofructokinase subunits and isozymes in ascites tumor cells and its original tissue, murine mammary gland.
Antitumor agents XXVII: Effects of helenalin on anaerobic and aerobic metabolism of Ehrlich ascites cells.
Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?
Association-dissociation behavior of erythrocyte phosphofructokinase and tumor pyruvate kinase.
Bcl-2 inhibits tumor necrosis factor-alpha-mediated increase of glycolytic enzyme activities and enhances pyruvate carboxylase activity.
Biochemical alterations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors from rats subjected to caloric restriction.
Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.
Breast Cancer Subtypes Underlying EMT-Mediated Catabolic Metabolism.
Cancer cell metabolism: implications for therapeutic targets.
Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo.
Cell proliferative modulation of MCG 101 sarcoma from mice exposed to hyperbaric oxygenation.
Cellular distribution of phosphofructokinase activity and implications to metabolic regulation in human breast cancer.
Characterization of two similar differential tumor markers based on phosphofructokinase activity arising from the influence of cancer patient serum.
Clotrimazole disrupts glycolysis in human breast cancer without affecting non-tumoral tissues.
CO-CBS-H2 S Axis: From Vascular Mediator to Cancer Regulator.
Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia.
Control of phosphofructokinase by fructose 2,6-bisphosphate in B-lymphocytes and B-chronic lymphocytic leukemia cells.
Differences in oxygen-dependent regulation of enzymes between tumor and normal cell systems in culture.
Differences in phosphofructokinase regulation in normal and tumor rat thyroid cells.
Differential expression of phosphofructokinase-1 isoforms correlates with the glycolytic efficiency of breast cancer cells.
Discover potential inhibitors for PFKFB3 using 3D-QSAR, virtual screening, molecular docking and molecular dynamics simulation.
Effect of the cancer specific shorter form of human 6-phosphofructo-1-kinase on the metabolism of the yeast Saccharomyces cerevisiae.
Electrophoretic study of phosphofructokinase isoenzymes from human tissues and tumours of the nervous system.
Endotoxin stimulation of liver parenchymal cell phosphofructokinase activity requires nonparenchymal cells.
Enzymes of glucose metabolism in cultured human gliomas: neoplasia is accompanied by altered hexokinase, phosphofructokinase, and glucose-6-phosphate dehydrogenase levels.
Evidence that does not support PKM2-catalyzed reaction as a rate-limiting step in cancer cell glycolysis.
Expression of a new set of glycolytic isozymes in activated human peripheral lymphocytes.
Flavonoids Targeting HIF-1: Implications on Cancer Metabolism.
Fructose 2,6-bisphosphate metabolism in Ehrlich ascites tumour cells.
Further analysis of the mode of inhibition and activation of Novikoff ascites tumor phosphofructokinase.
Glycolytic enzyme activities in breast cancer metastases.
Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
Hexokinase and phosphofructokinase activity and intracellular distribution correlate with aggressiveness and invasiveness of human breast carcinoma.
HIF-1alpha Modulates Energy Metabolism in Cancer Cells by Inducing Over-expression of Specific Glycolytic Isoforms.
HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.
High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose.
Hypoxia, glucose metabolism and the Warburg's effect.
Identification of a multienzyme complex for glucose metabolism in living cells.
Influence of insulin on estrogen-induced responses in the r3230ac mammary carcinoma.
Inhibition of phosphofructokinase by quinone methide and alpha-methylene lactone tumor inhibitors.
Isozyme pattern in serially xenotransplanted childhood tumors.
Kallikrein-related peptidase 6 can cleave human-muscle-type 6-phosphofructo-1-kinase into highly active shorter fragments.
Kinetic studies on phosphofructokinase from Ehrlich ascites tumor cells.
Metabolic characterization of three hamster melanoma variants.
Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1+ Cells.
Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry.
Metformin attenuates hepatoma cell proliferation by decreasing glycolytic flux through the HIF-1?/PFKFB3/PFK1 pathway.
Multiple forms of phosphofructokinase in rat tissues and rat tumors.
Nucleoredoxin regulates glucose metabolism via phosphofructokinase 1.
Partial Substitution of Glucose with Xylitol Suppressed the Glycolysis and Selectively Inhibited the Proliferation of Oral Cancer Cells.
PFKP is highly expressed in lung cancer and regulates glucose metabolism.
pH in human tumor xenografts and transplanted rat tumors: effect of insulin, inorganic phosphate, and m-iodobenzylguanidine.
Phosphofructokinase 1 Platelet Isoform Promotes ?-Catenin Transactivation for Tumor Development.
Phosphofructokinase C isozyme from ascites tumor cells: cloning, expression, and properties.
Phosphofructokinase from a mouse preputial gland tumour ESR-586.
Phosphofructokinase from Ehrlich ascites tumor.
Phosphofructokinase in human blood cells.
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
Phosphofructokinase type 1 kinetics, isoform expression and gene polymorphisms in cancer cells.
Phosphofructokinase-P Modulates P44/42 MAPK Levels in HeLa Cells.
Phosphofructokinase: A mediator of glycolytic flux in cancer progression.
PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma.
Platelet isoform of phosphofructokinase promotes aerobic glycolysis and the progression of non?small cell lung cancer.
Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism.
Prognostic Roles of Phosphofructokinase Platelet in Clear Cell Renal Cell Carcinoma and Correlation with Immune Infiltration.
Purification and some properties of phosphofructokinase from Ehrlich ascites tumor cells.
Pyruvate kinase and phosphofructokinase isozymes in childhood cancers.
Regulation of cellular energy metabolism: the Crabtree effect.
Regulation of glycolysis and oxygen consumption in lymph-node cells of normal and leukaemic mice.
Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress.
Specific activation by fructose 2,6-bisphosphate and inhibition by P-enolpyruvate of ascites tumor phosphofructokinase.
Specific characteristics of phosphofructokinase-microtubule interaction.
T-cell metabolism in autoimmune disease.
Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality.
The activity of phosphofructokinase and lactate dehydrogenase in cancer of the colon and rectum and the effect of iodine on the normal mucosa.
The biological significance of cancer: mitochondria as a cause of cancer and the inhibition of glycolysis with citrate as a cancer treatment.
The effect of levamisole on energy metabolism in Ehrlich ascites tumour cells in vitro.
The effect of magnesium on glycolysis of permeabilized Ehrlich ascites tumor cells.
The effect of Mg2+ upon 6-phosphofructokinase activity in Ehrlich ascites tumor cells in vivo.
The expression pattern of PFKFB3 enzyme distinguishes between induced-pluripotent stem cells and cancer stem cells.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
The impairment of respiration by glycolysis in the Lewis lung carcinoma.
The influence of PFK-II overexpression on neuroblastoma patients' survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4.
The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Tumor enzymes and prognosis in transitional cell carcinoma of the bladder: prediction of risk of progression in patients with superficial disease.
Versican expression level in cumulus cells is associated with human oocyte developmental competence.
Who controls the ATP supply in cancer cells? Biochemistry lessons to understand cancer energy metabolism.
Wnt signaling promotes tumor development in part through phosphofructokinase 1 platelet isoform upregulation.
[Phosphofructokinase activity in normal and tumor tissues of rats]
[Properties of phosphofructokinase from ascites tumor cells]
[Substrate and effector actions on the phosphofructokinase of ascites tumor cells]
[Suppression of phosphofructokinase (PFK) by sera from cancer patients, and mechanism of the antagonistic effect of PSK]
[The modification of phosphofructokinase in ascites tumor cells by different ions]
[The reverse phosphofructokinase reaction in ascites tumor cells (author's transl)]
Nervous System Neoplasms
Electrophoretic study of phosphofructokinase isoenzymes from human tissues and tumours of the nervous system.
Neuroblastoma
Effect of oxygen and glucose availability on the glycolytic rate in neuroblastoma cells under different conditions of culture.
Syntenic assignment of human chromosome 1 homologous loci in the bovine.
Obesity
Different types of postinsulin receptor defects contribute to insulin resistance in hearts of obese Zucker rats.
Mouse (C57BL/KsJ) liver phosphofructokinase. Allosteric kinetics and age-related changes in the genetically diabetic state.
Obesity and the regulation of phosphofructokinase in heart: an apparent insensitivity to adrenergic activation in mature-age genetically obese rats.
Optic Atrophy
Impact of Hypoxic Exercise Recovery on Skeletal Muscle Glycogen and Gene Expression.
Otosclerosis
Biochemical aberrations in otosclerosis. Activity and control of phosphofructokinase from human ossicles.
Pancreatic Neoplasms
MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.
Parasitic Diseases
Entamoeba histolytica: computer-assisted modeling of phosphofructokinase for the prediction of broad-spectrum antiparasitic agents.
phosphoglycerate kinase deficiency
Deficiencies of glycolytic enzymes as a possible cause of hemolytic anemia.
Plague
[Phosphofructokinase activity of the plague bacterium]
Pleural Effusion
[Suppression of phosphofructokinase (PFK) by sera from cancer patients, and mechanism of the antagonistic effect of PSK]
Pneumonia
[Erythrocyte phosphofructokinase activity in children with different forms of acute pneumonia during the 1st year of life]
[Hexokinase and phosphofructokinase activity in acute pneumonia in children in the 1st year of life]
Poliomyelitis
Prior poliomyelitis-reduced capillary supply and metabolic enzyme content in hypertrophic slow-twitch (type I) muscle fibres.
Polycythemia Vera
Erythrocyte phosphofructokinase alterations in polycythemia vera.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
All in for nuclear PFKP-induced CXCR4 metastasis: a T cell acute lymphoblastic leukemia prognostic marker.
Modifications of erythrocyte phosphofructokinase in children with acute lymphoblastic leukemia. Acute stage and remission.
Phosphofructokinase in human blood cells.
procollagen-proline 4-dioxygenase deficiency
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.
Protein Deficiency
Neonatal metabolic myopathies.
Psoriasis
The relation of hexose phosphates to the epidermal phosphofructokinase velocities in psoriasis.
[The skin activity of hexokinase, glucokinase and phosphofructokinase in psoriasis patients]
Pulmonary Disease, Chronic Obstructive
Metabolic characteristics of the deltoid muscle in patients with chronic obstructive pulmonary disease.
Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease.
QUADRICEPS METABOLISM DURING CONSTANT WORKRATE CYCLING EXERCISE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE.
Pulmonary Edema
Maternal nicotine exposure during pregnancy and lactation: I. Effect on glycolysis in the lungs of the offspring.
pyruvate kinase deficiency
Kinetic properties of mutant enzymes in erythrocyte phosphofructokinase deficiency and erythrocyte pyruvate kinase deficiency.
Renal Insufficiency, Chronic
Changes in glucose 6-phosphate dehydrogenase and phosphofructokinase activity during maturation and ageing of red blood cells in children with chronic renal insufficiency.
Retinal Degeneration
Neurochemical studies on the inherited retinal degeneration of the rat. 3. Hexokinase, phosphofructokinase and atpase in the developing retina.
Rhabdomyolysis
Juvenile-onset permanent weakness in muscle phosphofructokinase deficiency.
[Muscular glycogenesis and haemolytic anaemia due to enzyme deficiency in two siblings. Familial form of Tarui's disease due to a deficiency in muscular and erythrocytic phosphofructokinase (author's transl)]
Sarcoma
Syntenic assignment of human chromosome 1 homologous loci in the bovine.
[Glucose metabolism of Tawa sarcoma cells--inhibition of phosphofructokinase by citrate]
[Glycolytic metabolism in Tawa sarcoma cells: regulation of phosphofructokinase activity by its substrate]
[Regulation by ATP of phosphofructokinase from ascites Tawa sarcoma cells]
[Studies on the glycolytic metabolism in Tawa sarcoma cells: inhibition of phosphofructokinase activity from Tawa sarcoma cells by nucleotide triphosphate]
Seizures
Impaired hippocampal glucose metabolism during and after flurothyl-induced seizures in mice: Reduced phosphorylation coincides with reduced activity of pyruvate dehydrogenase.
Muscle phosphofructokinase deficiency with neonatal seizures and nonprogressive course.
Sepsis
Downregulation of diaphragm electron transport chain and glycolytic enzyme gene expression in sepsis.
Endotoxin causes reciprocal changes in hepatic nitric oxide synthesis, gluconeogenesis, and flux through phosphoenolpyruvate carboxykinase.
Hepatic phosphofructokinase-1 activity and fructose 2,6-bisphosphate levels in patients with abdominal sepsis.
Shock, Septic
Impaired energy metabolism in hearts of septic baboons: diminished activities of Complex I and Complex II of the mitochondrial respiratory chain.
Spasm
First description of phosphofructokinase deficiency in spain: identification of a novel homozygous missense mutation in the PFKM gene.
Starvation
CITRATE AS AN INTERMEDIARY IN THE INHIBITION OF PHOSPHOFRUCTOKINASE IN RAT HEART MUSCLE BY FATTY ACIDS, KETONE BODIES, PYRUVATE, DIABETES, AND STARVATION.
Disruption of the phosphate-starvation response of oilseed rape suspension cells by the fungicide phosphonate.
Dynamics and regulation of glycolysis-tricarboxylic acid metabolism in the midgut of Spodoptera litura during metamorphosis.
Effects of alloxan diabetes, starvation and hypophysectomy on total phosphofructokinase activity in rat heart.
Effects of starvation and streptozotocin-induced diabetes on the activity of phosphofructokinase in the epithelial cells of rat colon.
Enzyme activities of hepatic glucose utilization in the fed and fasting genetically obese mouse at 4-5 months of age.
Enzyme Sets of Glycolysis, Gluconeogenesis, and Oxidative Pentose Phosphate Pathway Are Not Complete in Nongreen Highly Purified Amyloplasts of Sycamore (Acer pseudoplatanus L.) Cell Suspension Cultures.
Fuel utilization in colonocytes of the rat.
Impaired 6-phosphofructokinase activity in mononuclear leukocytes from patients with type II diabetes mellitus.
Metabolic adaptation of the renal carbohydrate metabolism. I. Effects of starvation on the gluconeogenic and glycolytic fluxes in the proximal and distal renal tubules.
Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by lungs of the rat.
Phosphofructokinase activity and the binding of enzymes to glycogen particles in the perfused psoas muscle of the rabbit.
Rat-liver-type phosphofructokinase mRNA. Structure, tissue distribution and regulation.
Regulation of fatty acid synthesis in lactating rat mammary gland in the fed to starved transition: asynchronous control of pyruvate dehydrogenase, phosphofructokinase and acetyl-CoA carboxylase.
The effect of starvation on the control of phosphofructokinase activity in the epithelial cells of the rat small intestine.
The effect of thermal injury on the regulation of phosphofructokinase in the mucosa of rat small intestine.
The role of fructose 2,6-bisphosphate in the long-term control of phosphofructokinase in rat liver.
Stomach Neoplasms
3-Bromopyruvate and sodium citrate induce apoptosis in human gastric cancer cell line MGC-803 by inhibiting glycolysis and promoting mitochondria-regulated apoptosis pathway.
Stomach Ulcer
A new variant case of muscle phosphofructokinase deficiency, coexisting with gastric ulcer, gouty arthritis, and increased hemolysis.
Stroke
Phosphofructokinase-1 Inhibition Promotes Neuronal Differentiation of Neural Stem Cells and Functional Recovery After Stroke.
TDP-43 Proteinopathies
Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy.
Tetanus
Skeletal muscle metabolism in two Pavulon treated tetanus patients.
Thalassemia
Calcium in red blood cells-a perilous balance.
Thrombosis
Phosphofructokinase Deficiency and Portal and Mesenteric Vein Thrombosis.
Thymoma
Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma.
Thyroid Neoplasms
Isozymic composition and regulatory properties of phosphofructokinase from well-differentiated and anaplastic medullary thyroid carcinomas of the rat.
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
Triple Negative Breast Neoplasms
Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy.
Trypanosomiasis, African
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Tuberculosis
Characterization of phosphofructokinase activity in Mycobacterium tuberculosis reveals that a functional glycolytic carbon flow is necessary to limit the accumulation of toxic metabolic intermediates under hypoxia.
Correction: Characterization of Phosphofructokinase Activity in Mycobacterium tuberculosis Reveals That a Functional Glycolytic Carbon Flow Is Necessary to Limit the Accumulation of Toxic Metabolic Intermediates under Hypoxia.
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1? by Restriction of PFK-M via MicroRNA-21.
Uremia
[Muscle hexokinase and phosphofructokinase activity in patients with chronic uremia]
Urinary Bladder Neoplasms
Genetic alteration in phosphofructokinase family promotes growth of muscle-invasive bladder cancer.
Proteomic analysis of bladder cancer by iTRAQ after Bifidobacterium infantis-mediated HSV-TK/GCV suicide gene treatment.
Urolithiasis
[Phosphofructokinase activity in the serum and urine in patients with urolithiasis]
Uterine Cervical Neoplasms
Glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase P (PFKP) are good biomarkers of survival and potential therapeutic targets in cervical cancer.
Whooping Cough
Bordetella pertussis extract induces increase in the activities of glycolytic enzymes in mouse liver.