Reference on EC 2.6.1.62 - adenosylmethionine-8-amino-7-oxononanoate transaminase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Izumi, Y.; Tani, Y.; Ogata, K.
Microbiological biosynthesis of biotin
Methods Enzymol.
62
326-338
1979
Bacillus roseus, Corynebacterium glutamicum, Kocuria rosea, Salmonella enterica subsp. enterica serovar Typhimurium, Bacillus roseus IAM 1257
Stoner, G.L.; Eisenberg, M.A.
Purification and properties of 7,8-diaminopelargonic acid aminotransferase
J. Biol. Chem.
250
4029-4036
1975
Escherichia coli
Izumi, Y.; Sato, K.; Tani, Y.; Ogata, K.
Biosynthesis of biotin by microorganisms. XV. 7,8-Diaminopelargonic acid aminotransferase, an enzyme involved in biotin biosynthesis by microorganisms
Agric. Biol. Chem.
39
175-181
1975
Bacillus roseus, Corynebacterium glutamicum, Escherichia coli, Kocuria rosea, Salmonella enterica subsp. enterica serovar Typhimurium, Escherichia coli AKV 0015, Corynebacterium glutamicum NRRL 2311, Bacillus roseus IAM 1257
-
Izumi, Y.; Sato, K.; Tani, Y.; Ogata, K.
7,8-Diaminopelargonic acid aminotransferase, an enzyme involved in biotin biosynthesis by microorganisms
Agric. Biol. Chem.
37
2683-2684
1973
Bacillus roseus, Corynebacterium glutamicum, Escherichia coli, Kocuria rosea, Salmonella enterica subsp. enterica serovar Typhimurium, Bacillus roseus IAM 1257
-
Stoner, G.L.; Eisenberg, M.A.
Biosynthesis of 7,8-diaminopelargonic acid from 7-keto-8-aminopelargonic acid and S-adenosyl-L-methionine. The kinetics of the reaction
J. Biol. Chem.
250
4037-4043
1975
Corynebacterium glutamicum, Escherichia coli, Corynebacterium glutamicum NRRL 2311
Eisenberg, M.A.; Stoner, G.L.
7,8-Diaminopelargonic acid aminotransferase
Methods Enzymol.
62
342-347
1979
Escherichia coli
Eliot, A.C.; Sandmark, J.; Schneider, G.; Kirsch, J.F.
The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation
Biochemistry
41
12582-12589
2002
Escherichia coli
Kck, H.; Gibson, K.J.; Gatenby, A.A.; Schneider, G.; Lindqvist, Y.
Purification and preliminary x-ray crystallographic studies of recombinant 7,8-diaminopelargonic acid synthase from Escherichia coli
Acta Crystallogr. Sect. D
54
1397-1398
1998
Escherichia coli
Kck, H.; Sandmark, J.; Gibson, K.; Schneider, G.; Lindqvist, Y.
Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes
J. Mol. Biol.
291
857-876
1999
Escherichia coli
Eliot, A.C.; Kirsch, J.F.
Avoiding the road less traveled: how the topology of enzyme-substrate complexes can dictate product selection
Acc. Chem. Res.
36
757-765
2003
Escherichia coli
Mann, S.; Marquet, A.; Ploux, O.
Inhibition of 7,8-diaminopelargonic acid aminotransferase by amiclenomycin and analogues
Biochem. Soc. Trans.
33
802-805
2005
Escherichia coli, Mycobacterium tuberculosis
Sandmark, J.; Eliot, A.C.; Famm, K.; Schneider, G.; Kirsch, J.F.
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis
Biochemistry
43
1213-1222
2004
Escherichia coli (P12995), Escherichia coli
Van Arsdell, S.W.; Perkins, J.B.; Yocum, R.R.; Luan, L.; Howitt, C.L.; Chatterjee, N.P.; Pero, J.G.
Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction
Biotechnol. Bioeng.
91
75-83
2005
Bacillus subtilis
Breen, R.S.; Campopiano, D.J.; Webster, S.; Brunton, M.; Watt, R.; Baxter, R.L.
The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor
Org. Biomol. Chem.
1
3498-3499
2003
Escherichia coli
Mann, S.; Ploux, O.
7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target. Characterization and inhibition studies
FEBS J.
273
4778-4789
2006
Mycobacterium tuberculosis, Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis ATCC 25618 (P9WQ81)
Mann, S.; Colliandre, L.; Labesse, G.; Ploux, O.
Inhibition of 7,8-diaminopelargonic acid aminotransferase from Mycobacterium tuberculosis by chiral and achiral anologs of its substrate: biological implications
Biochimie
91
826-834
2009
Mycobacterium tuberculosis, Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis ATCC 25618 (P9WQ81)
Dey, S.; Lane, J.M.; Lee, R.E.; Rubin, E.J.; Sacchettini, J.C.
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase
Biochemistry
49
6746-6760
2010
Mycobacterium tuberculosis (P9WQ80), Mycobacterium tuberculosis, Mycobacterium tuberculosis CDC 1551 (P9WQ80)
Mann, S.; Eveleigh, L.; Lequin, O.; Ploux, O.
A microplate fluorescence assay for DAPA aminotransferase by detection of the vicinal diamine 7,8-diaminopelargonic acid
Anal. Biochem.
432
90-96
2013
Mycobacterium tuberculosis, Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis ATCC 25618 (P9WQ81)
Cobessi, D.; Dumas, R.; Pautre, V.; Meinguet, C.; Ferrer, J.L.; Alban, C.
Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis
Plant Cell
24
1608-1625
2012
Arabidopsis thaliana (B0F481), Arabidopsis thaliana
Shi, C.; Aldrich, C.C.
Design and synthesis of potential mechanism-based inhibitors of the aminotransferase BioA involved in biotin biosynthesis
J. Org. Chem.
77
6051-6058
2012
Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis ATCC 25618 (P9WQ81)
Dai, R.; Wilson, D.J.; Geders, T.W.; Aldrich, C.C.; Finzel, B.C.
Inhibition of Mycobacterium tuberculosis transaminase BioA by aryl hydrazines and hydrazides
ChemBioChem
15
575-586
2014
Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQ81)
Dai, R.; Geders, T.W.; Liu, F.; Park, S.W.; Schnappinger, D.; Aldrich, C.C.; Finzel, B.C.
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA
J. Med. Chem.
58
5208-5217
2015
Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis H37Rv (P9WQ81)
Billones, J.B.; Carrillo, M.C.; Organo, V.G.; Sy, J.B.; Clavio, N.A.; Macalino, S.J.; Emnacen, I.A.; Lee, A.P.; Ko, P.K.; Concepcion, G.P.
In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA)
Drug Des. Devel. Ther.
11
563-574
2017
Mycobacterium tuberculosis (A5U255), Mycobacterium tuberculosis (P9WQ81), Mycobacterium tuberculosis, Mycobacterium tuberculosis ATCC 25177 (A5U255), Mycobacterium tuberculosis H37Rv (P9WQ81), Mycobacterium tuberculosis ATCC 25618 (P9WQ81)
Bezsudnova, E.Y.; Stekhanova, T.N.; Popinako, A.V.; Rakitina, T.V.; Nikolaeva, A.Y.; Boyko, K.M.; Popov, V.O.
Diaminopelargonic acid transaminase from Psychrobacter cryohalolentis is active towards (S)-(-)-1-phenylethylamine, aldehydes and alpha-diketones
Appl. Microbiol. Biotechnol.
102
9621-9633
2018
Psychrobacter cryohalolentis (Q1QDV8), Psychrobacter cryohalolentis, Psychrobacter cryohalolentis DSM 17306 (Q1QDV8), Psychrobacter cryohalolentis K5 (Q1QDV8), Psychrobacter cryohalolentis VKM B-2378 (Q1QDV8), Psychrobacter cryohalolentis ATCC BAA-1226 (Q1QDV8)
Shi, F.; Si, H.; Ni, Y.; Zhang, L.; Li, Y.
Transaminase encoded by NCgl2515 gene of Corynebacterium glutamicum ATCC13032 is involved in gamma-aminobutyric acid decomposition
Process Biochem.
55
55-60
2017
Corynebacterium glutamicum (P46395), Corynebacterium glutamicum LMG 3730 (P46395), Corynebacterium glutamicum BCRC 11384 (P46395), Corynebacterium glutamicum ATCC 13032 (P46395), Corynebacterium glutamicum JCM 1318 (P46395), Corynebacterium glutamicum NCIMB 10025 (P46395), Corynebacterium glutamicum DSM 20300 (P46395)
-
html completed
