Information on EC 2.6.1.42 - branched-chain-amino-acid transaminase

Word Map on EC 2.6.1.42
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

EC NUMBER
COMMENTARY hide
2.6.1.42
-
RECOMMENDED NAME
GeneOntology No.
branched-chain-amino-acid transaminase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
amino group transfer
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Biosynthesis of antibiotics
-
-
Biosynthesis of secondary metabolites
-
-
Cysteine and methionine metabolism
-
-
Glucosinolate biosynthesis
-
-
L-alanine biosynthesis I
-
-
L-isoleucine biosynthesis I (from threonine)
-
-
L-isoleucine biosynthesis II
-
-
L-isoleucine biosynthesis III
-
-
L-isoleucine biosynthesis IV
-
-
L-isoleucine biosynthesis V
-
-
L-isoleucine degradation I
-
-
L-isoleucine degradation II
-
-
L-leucine biosynthesis
-
-
L-leucine degradation I
-
-
L-leucine degradation III
-
-
L-valine biosynthesis
-
-
L-valine degradation I
-
-
L-valine degradation II
-
-
leucine degradation IV
-
-
Metabolic pathways
-
-
Pantothenate and CoA biosynthesis
-
-
Valine, leucine and isoleucine biosynthesis
-
-
Valine, leucine and isoleucine degradation
-
-
alanine metabolism
-
-
isoleucine metabolism
-
-
leucine metabolism
-
-
valine metabolism
-
-
SYSTEMATIC NAME
IUBMB Comments
branched-chain-amino-acid:2-oxoglutarate aminotransferase
Also acts on L-isoleucine and L-valine, and thereby differs from EC 2.6.1.6, leucine transaminase, which does not. It also differs from EC 2.6.1.66, valine---pyruvate transaminase.
CAS REGISTRY NUMBER
COMMENTARY hide
9054-65-3
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
bovine
-
-
Manually annotated by BRENDA team
No.2247, ATCC 14067
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
strain W3110
-
-
Manually annotated by BRENDA team
IFO 3172, synonym Gluconobacter suboxydans
-
-
Manually annotated by BRENDA team
LM0230
-
-
Manually annotated by BRENDA team
macaque monkey
-
-
Manually annotated by BRENDA team
JJ, DSM 2067
-
-
Manually annotated by BRENDA team
PS, DSM 1537
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Sprague-Dawley
-
-
Manually annotated by BRENDA team
strain BY4742
-
-
Manually annotated by BRENDA team
bifunctional branched-chain aminotransferase and aspartate:prephenate aminotransferase, EC 2.6.1.79
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
virus-induced gene silencing of BCAT results in abnormal leaf development and loss of apical dominance, suppressed expression of BCAT causes changes in various endogenous hormones and abnormal plant development that can be correlated with transcriptional induction of the KNOX genes, NTH15 and NTH23
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-alpha-methylbenzylamine + pyruvate
alpha-methylbenzaldehyde + L-alanine
show the reaction diagram
2-(3-hydroxy-1-adamantyl)-2-oxoethanoic acid + L-glutamate
3-hydroxyadamantylglycine + 2-oxoglutarate
show the reaction diagram
2-oxo-3-methylvalerate + + gloxalate
L-isoleucine + glycine
show the reaction diagram
2-oxo-6-hydroxyhexanoic acid + L-glutamate
L-6-hydroxynorleucine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
2-oxoglutarate + L-isoleucine
L-glutamate + 3-methyl-2-oxopentanoate
show the reaction diagram
2-oxoglutarate + L-leucine
L-glutamate + 4-methyl-2-oxopentanoate
show the reaction diagram
2-oxoglutarate + L-valine
L-glutamate + 3-methyl-2-oxobutanoate
show the reaction diagram
2-oxohexanoate + L-glutamate
L-norleucine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
2-oxoisocaproate + L-glutamate
L-leucine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
2-oxoisovalerate + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
2-oxovalerate + L-glutamate
L-norvaline + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
3-methyl-2-oxobutanoate + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
-
-
-
r
3-methyl-2-oxobutanoic acid + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
3-methyl-2-oxobutyrate + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
3-methyl-2-oxobutyric acid + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
3-methyl-2-oxopentanoate + L-glutamate
L-isoleucine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
3-methyl-2-oxopentanoic acid + L-glutamate
L-isoleucine + 2-oxoglutarate
show the reaction diagram
3-methyl-2-oxovaleric acid + L-glutamate
L-isoleucine + 2-oxoglutarate
show the reaction diagram
4,4-dimethyl-2-oxopentanoate + L-glutamate
L-neopentylglycine + 2-oxoglutarate
show the reaction diagram
-
-
-
-
?
4-methyl-2-oxopentanoate + L-glutamate
L-leucine + 2-oxoglutarate
show the reaction diagram
-
-
-
?
4-methyl-2-oxopentanoic acid + L-glutamate
L-leucine + 2-oxoglutarate
show the reaction diagram
4-methyl-2-oxovaleric acid + L-glutamate
L-leucine + 2-oxoglutarate
show the reaction diagram
4-methylthio-2-oxobutanoate + L-glutamate
L-methionine + 2-oxoglutarate
show the reaction diagram
-
-
-
r
beta-chloro-L-alanine + ?
3-chloropyruvate + ?
show the reaction diagram
-
-
-
-
?
DL-2-aminoadipate + 2-oxoglutarate
3-oxohexanedioic acid + L-glutamate
show the reaction diagram
-
heart enzyme
-
-
r
DL-2-aminoheptanoate + 2-oxoglutarate
2-oxoheptanoate + L-glutamate
show the reaction diagram
DL-2-aminooctanoate + 2-oxobutanoate
2-oxooctanoate + L-2-aminobutanoate
show the reaction diagram
DL-2-aminopimelate + 2-oxoglutarate
2-oxoheptanedioate + L-glutamate
show the reaction diagram
-
heart enzyme
-
-
r
DL-allo-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
-
heart enzyme
-
-
r
glycine + 2-oxoglutarate
glyoxylate + L-glutamate
show the reaction diagram
-
0.4% of the activity with L-isoleucine
-
?
glycine + 2-oxoglutarate
L-glutamic acid + glyoxylate
show the reaction diagram
L-2-aminobutanoate + 4-methylthio-2-oxo-butanoate
2-oxobutanoate + L-methionine
show the reaction diagram
-
-
-
-
r
L-2-aminobutanoate + phenylpyruvate
2-oxobutanoate + L-phenylalanine
show the reaction diagram
L-2-aminobutyrate + 2-oxo-isopentanoate
2-oxobutanoate + L-valine
show the reaction diagram
-
-
-
-
r
L-2-aminobutyrate + 2-oxoglutarate
2-oxobutanoate + L-glutamate
show the reaction diagram
L-2-aminobutyrate + 4-methyl-2-oxopentanoate
2-oxobutanoate + L-leucine
show the reaction diagram
-
-
-
-
r
L-2-aminobutyrate + pyruvate
2-oxobutanoate + L-alanine
show the reaction diagram
-
-
-
-
r
L-alanine + 2-oxoglutarate
2-oxopropanoate + L-glutamate
show the reaction diagram
L-alanine + 2-oxoisohexanoate
pyruvate + L-leucine
show the reaction diagram
-
-
-
-
r
L-alanine + 2-oxoisopentanoate
pyruvate + L-valine
show the reaction diagram
-
-
-
-
r
L-alanine + 4-methyl-2-oxopentanoate
pyruvate + L-leucine
show the reaction diagram
L-alanine + glyoxylate
pyruvate + glycine
show the reaction diagram
-
-
-
-
?
L-alanine + pyruvate
pyruvate + L-alanine
show the reaction diagram
-
-
-
r
L-allo-isoleucine + 2-oxobutyrate
3-methyl-2-oxopentanoate + 2-aminobutyrate
show the reaction diagram
-
-
-
-
r
L-allo-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-allo-isoleucine + 2-oxohexanoate
3-methyl-2-oxopentanoate + 2-aminohexanoate
show the reaction diagram
-
-
-
-
r
L-allo-isoleucine + 2-oxoisohexanoate
3-methyl-2-oxopentanoate + L-leucine
show the reaction diagram
-
-
-
-
r
L-allo-isoleucine + 2-oxoisopentanoate
3-methyl-2-oxopentanoate + L-valine
show the reaction diagram
-
-
-
-
r
L-allo-isoleucine + 2-oxooctanoate
3-methyl-2-oxopentanoate + 2-aminooctanoate
show the reaction diagram
-
-
-
-
r
L-arginine + 2-oxoglutarate
2-oxo-5-guanidinopentanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-asparagine + 2-oxoglutarate
2,4-dioxo-4-aminobutanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-aspartate + 2-oxoglutarate
oxaloacetate + L-glutamate
show the reaction diagram
L-aspartate + 2-oxoisohexanoate
oxaloacetate + L-leucine
show the reaction diagram
-
-
-
-
r
L-aspartate + 2-oxoisopentanoate
oxaloacetate + L-valine
show the reaction diagram
-
-
-
-
r
L-cysteine + 2-oxoglutarate
2-oxo-3-thiobutyrate + L-glutamate
show the reaction diagram
L-glutamate + 2-oxo-3-methylpentanoate
2-oxoglutarate + L-isoleucine
show the reaction diagram
-
-
-
-
r
L-glutamate + 2-oxo-isohexanoate
2-oxoglutarate + L-leucine
show the reaction diagram
L-glutamate + 2-oxo-isopentanoate
2-oxoglutarate + L-valine
show the reaction diagram
L-glutamate + 2-oxobutyrate
2-oxoglutarate + 2-aminobutyrate
show the reaction diagram
-
-
-
-
r
L-glutamate + 2-oxoglutarate
2-oxoglutarate + L-glutamate
show the reaction diagram
L-glutamate + 3-methyl-2-oxopentanoate
2-oxoglutarate + L-isoleucine
show the reaction diagram
-
-
-
r
L-glutamate + 4-methyl-2-oxopentanoate
2-oxoglutarate + L-leucine
show the reaction diagram
L-glutamate + 4-methylthio-2-oxo-butanoate
2-oxoglutarate + L-methionine
show the reaction diagram
L-glutamate + gloxalate
2-oxoglutarate + glycine
show the reaction diagram
L-glutamate + pyruvate
2-oxoglutarate + L-alanine
show the reaction diagram
-
-
-
-
r
L-glutamine + 2-oxoglutarate
2,5-dioxo-5-aminopentanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-histidine + 2-oxoglutarate
2-oxo-3-imidazolpropanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-homomethionine + 2-oxoglutarate
5-methylthio-2-oxopentanoate + L-glutamate
show the reaction diagram
-
-
-
-
?
L-isoleucine + 2-oxo-3-methylpentanoate
2-oxoisohexanoate + L-isoleucine
show the reaction diagram
-
-
-
-
r
L-isoleucine + 2-oxo-isopentanoate
2-oxoisohexanoate + L-valine
show the reaction diagram
L-isoleucine + 2-oxobutanoate
3-methyl-2-oxopentanoate + 2-aminobutanoate
show the reaction diagram
-
-
-
-
r
L-isoleucine + 2-oxobutyrate
2-oxoisohexanoate + 2-aminobutyrate
show the reaction diagram
L-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
L-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoic acid + L-glutamate
show the reaction diagram
L-isoleucine + 2-oxoglutarate
L-glutamate + 3-methyl-2-oxopentanoate
show the reaction diagram
L-isoleucine + 2-oxohexanoate
L-norleucine + 2-oxoisohexanoate
show the reaction diagram
-
-
-
-
r
L-isoleucine + 2-oxoisocaproate
3-methyl-2-oxopentanoate + L-leucine
show the reaction diagram
-
-
-
r
L-isoleucine + 2-oxoisohexanoate
3-methyl-2-oxopentanoate + L-leucine
show the reaction diagram
L-isoleucine + 2-oxooctanoate
2-oxoisohexanoate + 2-aminooctanoate
show the reaction diagram
-
-
-
-
r
L-isoleucine + 3-methyl-2-oxobutanoate
3-methyl-2-oxopentanoate + L-valine
show the reaction diagram
-
-
-
-
r
L-isoleucine + 3-methylthio-2-oxobutanoate
3-methyl-2-oxopentanoate + 2-amino-3-methylthiobutanoate
show the reaction diagram
-
-
-
-
r
L-isoleucine + 3-phenylpyruvate
2-oxoisohexanoate + L-phenylalanine
show the reaction diagram
-
-
-
r
L-isoleucine + 4-methylthio-2-oxo-butanoate
3-methyl-2-oxopentanoate + L-methionine
show the reaction diagram
L-isoleucine + 4-methylthio-2-oxobutyrate
3-methyl-2-oxopentanoate + L-methionine
show the reaction diagram
-
-
-
r
L-isoleucine + glyoxylate
2-oxoisohexanoate + glycine
show the reaction diagram
-
-
-
-
r
L-isoleucine + oxaloacetate
2-oxoisohexanoate + L-aspartate
show the reaction diagram
-
-
-
-
r
L-isoleucine + oxaloacetate
3-methyl-2-oxopentanoate + L-aspartate
show the reaction diagram
-
brain enzyme
-
-
r
L-isoleucine + pyruvate
2-oxoisohexanoate + L-alanine
show the reaction diagram
L-leucine + 2-oxo-3-methiobutyrate
2-oxoisohexanoate + L-methionine
show the reaction diagram
-
-
-
-
r
L-leucine + 2-oxo-3-methylpentanoate
2-oxoisohexanoate + L-isoleucine
show the reaction diagram
L-leucine + 2-oxo-butyrate
2-oxoisohexanoate + 2-aminobutyrate
show the reaction diagram
L-leucine + 2-oxo-hexanoate
2-oxoisohexanoate + 2-aminohexanoate
show the reaction diagram
-
-
-
-
r
L-leucine + 2-oxo-isohexanoate
2-oxoisohexanoate + L-leucine
show the reaction diagram
L-leucine + 2-oxo-pentanoate
2-oxoisohexanoate + 2-aminopentanoate
show the reaction diagram
-
-
-
-
r
L-leucine + 2-oxobutanoate
2-oxoisohexanoate + L-valine
show the reaction diagram
-
-
-
r
L-leucine + 2-oxoglutarate
2-oxoisohexanoate + L-glutamate
show the reaction diagram
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoic acid + L-glutamate
show the reaction diagram
L-leucine + 2-oxoglutarate
L-glutamate + 4-methyl-2-oxopentanoate
show the reaction diagram
L-leucine + 2-oxohexanoate
2-oxoisohexanoate + 2-aminohexanoate
show the reaction diagram
-
-
-
-
r
L-leucine + 2-oxohexanoic acid
4-methyl-2-oxopentanoate + 2-aminohexanoic acid
show the reaction diagram
-
214% of the activity with 2-oxoglutarate
-
-
?
L-leucine + 2-oxoisohexanoate
2-oxoisohexanoate + L-leucine
show the reaction diagram
L-leucine + 2-oxoisopentanoate
2-oxoisohexanoate + L-valine
show the reaction diagram
L-leucine + 2-oxoisovaleric acid
4-methyl-2-oxopentanoate + 2-aminoisovaleric acid
show the reaction diagram
-
135% of the activity with 2-oxoglutarate
-
-
?
L-leucine + 2-oxooctanoate
2-oxoisohexanoate + 2-aminooctanoate
show the reaction diagram
-
-
-
-
r
L-leucine + 3-methyl-2-oxobutanoate
4-methyl-2-oxopentanoate + L-valine
show the reaction diagram
L-leucine + 3-methyl-2-oxopentanoate
2-oxo-4-methylpentanoate + L-isoleucine
show the reaction diagram
-
-
-
-
r
L-leucine + 3-methyl-2-oxopentanoate
4-methyl-2-oxopentanoate + L-isoleucine
show the reaction diagram
L-leucine + 4-methyl-2-oxopentanoate
L-glutamate + 2-oxoglutarate
show the reaction diagram
L-leucine + 4-methylthio-2-oxo-butanoate
4-methyl-2-oxopentanoate + L-methionine
show the reaction diagram
L-leucine + DL-2-oxo-3-methylpentanoate
2-oxoisohexanoate + L-isoleucine
show the reaction diagram
L-leucine + glyoxylate
2-oxoisohexanoate + glycine
show the reaction diagram
-
-
-
-
r
L-leucine + oxaloacetate
2-oxoisohexanoate + L-asparagine
show the reaction diagram
-
-
-
-
r
L-leucine + p-hydroxyphenylpyruvate
2-oxoisohexanoate + L-tyrosine
show the reaction diagram
L-leucine + phenylpyruvate
2-oxoisohexanoate + L-phenylalanine
show the reaction diagram
L-leucine + prephenate
2-oxoisohexanoate + 1-(2-amino-2-carboxyethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid
show the reaction diagram
-
-
-
-
r
L-leucine + pyruvate
2-oxoisohexanoate + L-alanine
show the reaction diagram
L-leucine + pyruvate
4-methyl-2-oxopentanoate + L-alanine
show the reaction diagram
L-lysine + 2-oxoglutarate
2-oxo-6-aminohexanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-methionine + 2-oxo-isohexanoate
4-methylsulfanyl-2-oxobutanoate + L-leucine
show the reaction diagram
-
-
-
-
r
L-methionine + 2-oxobutanoate
4-methylthio-2-oxobutanoate + L-2-aminobutanoate
show the reaction diagram
-
-
-
-
r
L-methionine + 2-oxobutyrate
4-methylsulfanyl-2-oxobutanoate + 2-aminobutyrate
show the reaction diagram
-
-
-
-
r
L-methionine + 2-oxoglutarate
4-methylsulfanyl-2-oxobutanoate + L-glutamate
show the reaction diagram
L-methionine + 2-oxoglutarate
4-methylthio-2-oxobutanoate + L-glutamate
show the reaction diagram
L-methionine + pyruvate
4-methylsulfanyl-2-oxobutanoate + L-alanine
show the reaction diagram
-
-
-
-
r
L-norleucine + 2-oxoglutarate
2-oxohexanoate + L-glutamate
show the reaction diagram
L-norleucine + 2-oxoisocaproate
2-oxohexanoate + L-leucine
show the reaction diagram
-
-
-
r
L-norleucine + 4-methyl-2-oxopentanoate
2-oxohexanoate + L-leucine
show the reaction diagram
-
-
-
-
r
L-norvaline + 2-oxocaproate
2-oxopentanoate + 2-aminohexanoate
show the reaction diagram
-
-
-
r
L-norvaline + 2-oxoglutarate
2-oxopentanoate + L-glutamate
show the reaction diagram
L-norvaline + 4-methyl-2-oxopentanoate
2-oxopentanoate + L-leucine
show the reaction diagram
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
show the reaction diagram
L-phenylalanine + 2-oxovalerate
phenylpyruvate + L-norvaline
show the reaction diagram
-
-
-
r
L-phenylalanine + 4-methylthio-2-oxo-butanoate
phenylpyruvate + L-methionine
show the reaction diagram
L-serine + 2-oxoglutarate
3-hydroxy-2-oxopropanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-threo-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-threonine + 2-oxoglutarate
2-oxo-3-hydroxybutyrate + L-glutamate
show the reaction diagram
-
-
-
-
r
L-tryptophan + 2-oxoglutarate
2-oxo-3-indolylpropanoate + L-glutamate
show the reaction diagram
L-tryptophan + 2-oxoglutarate
L-glutamic acid + 3-indole-2-oxopropanoate
show the reaction diagram
L-tyrosine + 2-oxoglutarate
p-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
L-valine + 2-oxo-3-methylpentanoate
3-methyl-2-oxobutanoate + L-isoleucine
show the reaction diagram
-
-
-
-
r
L-valine + 2-oxo-isohexanoate
2-oxoisopentanoate + L-leucine
show the reaction diagram
-
-
-
-
r
L-valine + 2-oxobutyrate
2-oxoisopentanoate + 2-aminobutanoate
show the reaction diagram
L-valine + 2-oxoglutarate
2-oxoisopentanoate + L-glutamate
show the reaction diagram
L-valine + 2-oxoglutarate
3-methyl-2-oxobutanoate + L-glutamate
show the reaction diagram
L-valine + 2-oxoglutarate
3-methyl-2-oxobutanoic acid + L-glutamate
show the reaction diagram
L-valine + 2-oxoglutarate
L-glutamate + 3-methyl-2-oxobutanoate
show the reaction diagram
L-valine + 2-oxohexanoate
2-oxoisopentanoate + 2-aminohexanoate
show the reaction diagram
-
-
-
-
r
L-valine + 2-oxoisopentanoate
2-oxoisopentanoate + L-valine
show the reaction diagram
L-valine + 2-oxoisovalerate
2-oxoisovalerate + L-leucine
show the reaction diagram
-
-
-
r
L-valine + 2-oxooctanoate
2-oxoisopentanoate + 2-aminooctanoate
show the reaction diagram
-
-
-
-
r
L-valine + 3-methyl-2-oxopentanoate
3-methyl-2-oxobutanoate + L-isoleucine
show the reaction diagram
-
-
-
-
r
L-valine + 4-methyl-2-oxopentanoate
2-oxoisopentanoate + L-leucine
show the reaction diagram
L-valine + 4-methylthio-2-oxo-butanoate
2-oxoisopentanoate + L-methionine
show the reaction diagram
-
-
-
-
?
L-valine + glyoxylate
2-oxoisopentanoate + glycine
show the reaction diagram
-
-
-
-
r
L-valine + oxaloacetate
2-oxoisopentanoate + L-aspartate
show the reaction diagram
-
-
-
-
r
L-valine + pyruvate
2-oxoisopentanoate + L-alanine
show the reaction diagram
L-valine + pyruvate
3-methyl-2-oxobutanoate + L-alanine
show the reaction diagram
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine + ?
S-(1,1,2,2-tetrafluoroethyl)-2-oxo-3-thiobutyrate + ?
show the reaction diagram
-
-
-
-
?
S-(1,2-dichlorovinyl)-L-cysteine + ?
S-(1,2-dichlorovinyl)-2-oxo-3-thiobutyrate + ?
show the reaction diagram
-
-
-
-
?
S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine + ?
S-(2-chloro-1,1,2-trifluoroethyl)-2-oxo-3-thiobutyrate + ?
show the reaction diagram
-
-
-
-
?
S-methyl-L-cysteine + 2-oxoglutarate
3-(methylthio)-2-oxopropanoic acid + L-glutamate
show the reaction diagram
-
heart enzyme
-
-
r
trimethylpyruvate + L-glutamate
L-tert-leucine + 2-oxoglutarate
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
3-methyl-2-oxobutyrate + L-glutamate
L-valine + 2-oxoglutarate
show the reaction diagram
-
the transamination of ketoisovalerate (KIV) to valine is carried out mainly by the transaminase B enzyme, with the transaminase C enzyme playing a minor role
-
-
?
L-isoleucine + 2-oxoglutarate
3-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
L-leucine + 2-oxoglutarate
2-oxoisohexanoate + L-glutamate
show the reaction diagram
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
show the reaction diagram
L-valine + 2-oxoglutarate
3-methyl-2-oxobutanoate + L-glutamate
show the reaction diagram
additional information
?
-
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
pyridoxal 5'-phosphate
pyridoxamine 5'-phosphate
-
Km 0.00062 mM
additional information
-
pyridoxine 5'-phosphate, pyridoxal, pyridoxamine and pyridoxine are not effective as coenzymes
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