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Disease on EC 2.6.1.4 - glycine transaminase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.
Adenocarcinoma of Lung
Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFN? axis.
Adenoma
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.
Atherosclerosis
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.
Breast Neoplasms
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer.
Identification of Breast Cancer DNA Methylation Markers Optimized for Fine Needle Aspiration Samples.
Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer.
PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3?/?-catenin/cyclin D1 signaling pathway in ER-negative breast cancer.
The breast cancer oncogene IKK? coordinates mitochondrial function and serine metabolism.
Carcinogenesis
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3?/?-catenin/cyclin D1 signaling pathway in ER-negative breast cancer.
PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells.
Carcinoma
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.
Carcinoma, Hepatocellular
Long non-coding RNA RP4-694A7.2 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the Regulation of PSAT1.
Carcinoma, Non-Small-Cell Lung
PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells.
Carcinoma, Ovarian Epithelial
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
Colonic Neoplasms
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.
Colorectal Neoplasms
Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil.
Identification and validation of PSAT1 as a potential prognostic factor for predicting clinical outcomes in patients with colorectal carcinoma.
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.
miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer.
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.
Overexpression of PSAT1 regulated by G9A sustains cell proliferation in colorectal cancer.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency.
Contracture
On the phenotypic spectrum of serine biosynthesis defects.
Diabetes Mellitus, Type 2
Hepatic phosphoserine aminotransferase 1 (PSAT1) regulates insulin sensitivity in mice via tribbles homolog 3 (TRB3).
Esophageal Neoplasms
MicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1.
Esophageal Squamous Cell Carcinoma
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Glioblastoma
Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma.
Glioma
Overexpression of PSAT1 Gene is a Favorable Prognostic Marker in Lower-Grade Gliomas and Predicts a Favorable Outcome in Patients with IDH1 Mutations and Chromosome 1p19q Codeletion.
Glucose Intolerance
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.
Hyperlipidemias
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.
Hyperoxaluria
High-performance liquid chromatographic microassay for L-glutamate:glyoxylate aminotransferase activity in human liver. Application in primary hyperoxaluria type 1.
Hyperoxaluria, Primary
Enzymological characterization of a feline analogue of primary hyperoxaluria type 2: a model for the human disease.
High-performance liquid chromatographic microassay for L-glutamate:glyoxylate aminotransferase activity in human liver. Application in primary hyperoxaluria type 1.
Infections
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.
Insulin Resistance
Hepatic phosphoserine aminotransferase 1 (PSAT1) regulates insulin sensitivity in mice via tribbles homolog 3 (TRB3).
Intracranial Aneurysm
Restored microRNA-133a-3p or Depleted PSAT1 Restrains Endothelial Cell Damage-Induced Intracranial Aneurysm Via Suppressing the GSK3?/?-Catenin Pathway.
Lung Neoplasms
Knock-down of PSAT1 Enhances Sensitivity of NSCLC Cells to Glutamine-limiting Conditions.
Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells.
Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFN? axis.
PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells.
Lymphatic Metastasis
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
Melanoma
Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non-Small Cell Lung Cancer Cells.
Microcephaly
On the phenotypic spectrum of serine biosynthesis defects.
Nasopharyngeal Carcinoma
Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor Prognosis.
Nasopharyngitis
EBV-miR-BART1 is involved in regulating metabolism-associated genes in nasopharyngeal carcinoma.
Neoplasm Metastasis
Long non-coding RNA RP4-694A7.2 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the Regulation of PSAT1.
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.
Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFN? axis.
PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3?/?-catenin/cyclin D1 signaling pathway in ER-negative breast cancer.
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
Selective loss of phosphoserine aminotransferase 1 (PSAT1) suppresses migration, invasion, and experimental metastasis in triple negative breast cancer.
Neoplasms
Expression of metabolism-related proteins in invasive lobular carcinoma: comparison to invasive ductal carcinoma.
Expression of serine and glycine-related enzymes in phyllodes tumor.
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.
Hepatic transcriptome and proteome analyses provide new insights into the regulator mechanism of dietary avicularin in diabetic mice.
Identification of molecular marker associated with ovarian cancer prognosis using bioinformatics analysis and experiments.
Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
MicroRNA-340 Inhibits Esophageal Cancer Cell Growth and Invasion by Targeting Phosphoserine Aminotransferase 1.
Nf1 loss promotes Kras-driven lung adenocarcinoma and results in Psat1-mediated glutamate dependence.
Nuclear Pyruvate Kinase M2 (PKM2) Contributes to Phosphoserine Aminotransferase 1 (PSAT1)-Mediated Cell Migration in EGFR-Activated Lung Cancer Cells.
Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts.
Overexpression of Phosphoserine Aminotransferase 1 (PSAT1) Predicts Poor Prognosis and Associates with Tumor Progression in Human Esophageal Squamous Cell Carcinoma.
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.
Overexpression of PSAT1 Gene is a Favorable Prognostic Marker in Lower-Grade Gliomas and Predicts a Favorable Outcome in Patients with IDH1 Mutations and Chromosome 1p19q Codeletion.
Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFN? axis.
Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor Prognosis.
Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer.
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3?/?-catenin/cyclin D1 signaling pathway in ER-negative breast cancer.
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells.
Selective loss of phosphoserine aminotransferase 1 (PSAT1) suppresses migration, invasion, and experimental metastasis in triple negative breast cancer.
The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.
Weighted gene correlation network analysis identifies the critical long non-coding RNAs participate in the progression of osteosarcoma.
Osteosarcoma
Therapeutic potential of targeting HSPA5 through dual regulation of two candidate prognostic biomarkers ANXA1 and PSAT1 in osteosarcoma.
Weighted gene correlation network analysis identifies the critical long non-coding RNAs participate in the progression of osteosarcoma.
Ovarian Neoplasms
Differential expression analysis in ovarian cancer: A functional genomics and systems biology approach.
Identification of molecular marker associated with ovarian cancer prognosis using bioinformatics analysis and experiments.
Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.
PSAT1 Regulated Oxidation-Reduction Balance Affects the Growth and Prognosis of Epithelial Ovarian Cancer.
phosphoserine transaminase deficiency
Phosphoserine aminotransferase deficiency: imaging findings in a child with congenital microcephaly.
Pneumocystis Infections
Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages.
Sarcoma, Ewing
Menin regulates the serine biosynthetic pathway in Ewing sarcoma.
Seizures
On the phenotypic spectrum of serine biosynthesis defects.
Teratoma
Psat1-Dependent Fluctuations in ?-Ketoglutarate Affect the Timing of ESC Differentiation.
Uterine Cervical Neoplasms
PSAT1 Upregulation Contributes to Cell Growth and Cisplatin Resistance in Cervical Cancer Cells via Regulating PI3K/AKT Signaling Pathway.