Reference on EC 2.5.1.49 - O-acetylhomoserine aminocarboxypropyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Morinaga, Y.; Tani, Y.; Yamada, H.
Biosynthesis of homocysteine in a facultative methylotroph, Pseudomonas FM518
Agric. Biol. Chem.
47
2855-2860
1983
Pseudomonas sp., Pseudomonas sp. FM518
-
Yamagata, S.; Takeshima, K.; Naiki, N.
Evidence for the identity of O-acetylserine sulfhydrylase with O-acetylhomoserine sulfhydrylase in yeast
J. Biochem.
75
1221-1229
1974
Saccharomyces cerevisiae
Yamagata, S.; Takeshima, K.
O-Acetylserine and O-acetylhomoserine sulfhydrylase of yeast. Further purification and characterization as a pyridoxal enzyme
J. Biochem.
80
777-785
1976
Saccharomyces cerevisiae
Yamagata, S.
O-Acetylserine and O-acetylhomoserine sulfhydrylase of yeast. Subunit structure
J. Biochem.
80
787-797
1976
Saccharomyces cerevisiae
Yamagata, S.
Occurrence of low molecular weight O-acetylserine sulfhydrylase in the yeast Saccharomyces cerevisiae
J. Biochem.
88
1419-1423
1980
Saccharomyces cerevisiae
Smith, I.K.; Thompson, J.F.
Utilization of S-methylcysteine and methylmercaptan by methionineless mutants of Neurospora and the pathway of their conversion to methionine. II. Enzyme studies
Biochim. Biophys. Acta
184
130-138
1969
Neurospora sp.
Kerr, D.S.
O-Acetylhomoserine sulfhydrylase (Neurospora)
Methods Enzymol.
17
446-450
1971
Neurospora crassa
-
Kerr, D.S.
O-Acetylhomoserine sulfhydrylase from Neurospora. Purification and consideration of its function in homocysteine and methionine synthesis
J. Biol. Chem.
246
95-102
1971
Neurospora crassa
Yamagata, S.
Homocysteine in yeast. Partial purification and properties of O-acetylhomoserine sulfhydrylase
J. Biochem.
70
1035-1045
1971
Saccharomyces cerevisiae
Yamagata, S.; Takeshima, K.; Naiki, N.
O-acetylserine and O-acetylhomoserine sulfhydrylase of yeast; studies with methionine auxotrophs
J. Biochem.
77
1029-1036
1975
Saccharomyces cerevisiae
Murooka,Y.; Kakihara, K.; Miwa, T.; Seto, K.; Harada, T.
O-Alkylhomoserine synthesis catalyzed by O-acetylhomoserine sulfhydrylase in microorganisms
J. Bacteriol.
130
62-73
1977
Corynebacterium acetophilum, Corynebacterium acetophilum A51
Ozaki, H.; Shiio, I.
Methionine biosynthesis in Brevibacterium flavum: Properties and essential role of O-acetylhomoserine sulfhydrylase
J. Biochem.
91
1163-1171
1982
[Brevibacterium] flavum
Yamagata, S.
O-Acetylhomoserine sulfhydrylase of the fission yeast Schizosaccharomyces pombe: Partial purification, characterization, and its probable role in homocysteine biosynthesis
J. Biochem.
96
1511-1523
1984
Schizosaccharomyces pombe
Chocat, P.; Esaki, N.; Tanaka, H.; Soda, K.
Synthesis of selenocystine and selenohomocystine with O-acetylhomoserine sulfhydrylase
Agric. Biol. Chem.
49
1143-1150
1985
Saccharomyces cerevisiae
-
Yamagata, S.; Paszewski, A.; Lewandowska, I.
Purification and properties of O-acetyl-L-homoserine O-sulfhydrylase from Aspergillus nidulans
J. Gen. Appl. Microbiol.
36
137-141
1990
Aspergillus nidulans, Aspergillus nidulans sG8
-
Brzywczy, J.; Yamagata, S.; Paszewski, A.
Comparative studies on O-acetylhomoserine sulfhydrylase: physiological role and characterization of the Aspergillus nidulans enzyme
Acta Biochim. Pol.
40
421-427
1993
Aspergillus nidulans, Aspergillus nidulans sG8
Yamagata, S.; Isaji, M.; Nakamura, K.; Fujisaki, S.; Doi, K.; Bawden, S.; D'Andrea, R.
Overexpression of the Saccharomyces cerevisiae MET17/MET25 gene in Escherichia coli and comparative characterization of the product with O-acetylserine-O-acetylhomoserine sulfhydrylase of the yeast
Appl. Microbiol. Biotechnol.
42
92-99
1994
Saccharomyces cerevisiae
Shimizu, H.; Yamagata, S.; Masui, R.; Inoue,Y.; Shibata, T.; Yokoyama, S.; Kuramitsu, S.; Iwama, T.
Cloning and overexpression of the oah1 gene encoding O-acetyl-L-homoserine sulfhydrylase of Thermus thermophilus HB8 and characterization of the gene product
Biochim. Biophys. Acta
1549
61-72
2001
Thermus thermophilus (Q93I77), Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q93I77)
Lambert, B.D.; Titgemeyer, E.C.; Stokka, G.L.; DeBey, B.M.; Loest, C.A.
Methionine supply to growing steers affects hepatic activities of methionine synthase and betaine-homocysteine methyltransferase, but not cystathionine synthase
J. Nutr.
132
2004-2009
2002
Bos taurus
Hacham, Y.; Gophna, U.; Amir, R.
In vivo analysis of various substrates utilized by cystathionine gamma-synthase and O-acetylhomoserine sulfhydrylase in methionine biosynthesis
Mol. Biol. Evol.
20
1513-1520
2003
Saccharomyces cerevisiae (P06106), Leptospira meyeri (P94890), Leptospira meyeri
Iwama, T.; Hosokawa, H.; Lin, W.; Shimizu, H.; Kawai, K.; Yamagata, S.
Comparative characterization of the oah2 gene homologous to the oah1 of Thermus thermophilus HB8
Biosci. Biotechnol. Biochem.
68
1357-1361
2004
Thermus thermophilus (Q76K51), Thermus thermophilus HB8 / ATCC 27634 / DSM 579 (Q76K51)
Qin, X.; Martin, S.A.
Cloning of the O-acetylhomoserine sulfhydrylase gene from the ruminal bacterium selenomonas ruminantium HD4
CURR. MICROBIOL.
48
305-311
2004
Selenomonas ruminantium (AY257545), Selenomonas ruminantium, Selenomonas ruminantium HD4 (AY257545), Selenomonas ruminantium HD4
Omura, H.; Ikemoto, M.; Kobayashi, M.; Shimizu, S.; Yoshida, T.; Nagasawa, T.
Purification, characterization and gene cloning of thermostable o-acetyl-L-homoserine sulfhydrylase forming gamma-cyano-alpha-aminobutyric acid
J. BIOSCI. BIOENG.
96
53-58
2003
Geobacillus stearothermophilus, Geobacillus stearothermophilus CN3
Yeom, H.J.; Hwang, B.J.; Lee, M.S.; Kim, Y.; Lee, H.S.
Regulation of enzymes involved in methionine biosynthesis in Corynebacterium glutamicum
J. Microbiol. Biotechnol.
14
373-378
2004
Corynebacterium glutamicum
-
Matityahu, I.; Kachan, L.; Bar Ilan, I.; Amir, R.
Transgenic tobacco plants overexpressing the Met25 gene of Saccharomyces cerevisiae exhibit enhanced levels of cysteine and glutathione and increased tolerance to oxidative stress
Amino Acids
30
185-194
2006
Saccharomyces cerevisiae
Tang, C.; Zhang, Z.; Xu, B.; Li, M.; Liu, J.; Cui, J.
Two newly synthesized 5-methyltetrahydrofolate-like compounds inhibit methionine synthase activity accompanied by cell cycle arrest in G1/S phase and apoptosis in vitro
Anticancer Drugs
19
697-704
2008
Homo sapiens
Ott, N.; Geddert, H.; Sarbia, M.
Polymorphisms in methionine synthase (A2756G) and cystathionine beta-synthase (844ins68) and susceptibility to carcinomas of the upper gastrointestinal tract
J. Cancer Res. Clin. Oncol.
134
405-410
2008
Homo sapiens
Lima, C.S.; Ortega, M.M.; Ozelo, M.C.; Araujo, R.C.; De Souza, C.A.; Lorand-Metze, I.; Annichino-Bizzacchi, J.M.; Costa, F.F.
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk
Leuk. Res.
32
401-405
2008
Homo sapiens
Tran, T.H.; Krishnamoorthy, K.; Begley, T.P.; Ealick, S.E.
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes
Acta Crystallogr. Sect. D
67
831-838
2011
Wolinella succinogenes (Q7M844), Wolinella succinogenes
Yin, J.; Garen, C.R.; Bateman, K.; Yu, M.; Lyon, E.Z.; Habel, J.; Kim, H.; Hung, L.W.; Kim, C.Y.; James, M.N.
Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis
Acta Crystallogr. Sect. F
67
959-963
2011
Mycobacterium tuberculosis (L7N4M1), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (L7N4M1)
Bolten, C.J.; Schroeder, H.; Dickschat, J.; Wittmann, C.
Towards methionine overproduction in Corynebacterium glutamicum - methanethiol and dimethyldisulfide as reduced sulfur sources
J. Microbiol. Biotechnol.
20
1196-1203
2010
Corynebacterium glutamicum
Kulikova, V.V.; Revtovich, S.V.; Bazhulina, N.P.; Anufrieva, N.V.; Kotlov, M.I.; Koval, V.S.; Morozova, E.A.; Hayashi, H.; Belyi, Y.F.; Demidkina, T.V.
Identification of O-acetylhomoserine sulfhydrylase, a putative enzyme responsible for methionine biosynthesis in Clostridioides difficile Gene cloning and biochemical characterizations
IUBMB Life
71
1815-1823
2019
Clostridioides difficile (Q187D4), Clostridioides difficile, Clostridioides difficile 630 (Q187D4)
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