Information on EC 2.4.1.B50 - monoglucosylarchaeol synthase

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The expected taxonomic range for this enzyme is: Methanothermobacter thermautotrophicus

EC NUMBER
COMMENTARY hide
2.4.1.B50
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
monoglucosylarchaeol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucose + archaeol = UDP + 1,2-bis-phytanyl-sn-glycero-3-O-beta-D-glucoside
show the reaction diagram
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-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
lipid metabolism
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SYSTEMATIC NAME
IUBMB Comments
UDP-alpha-D-glucose:archaeol beta-D-glucosyltransferase
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-glucose + 1,2-bis-O-phytanyl-sn-glycerol
UDP + ?
show the reaction diagram
UDP-alpha-D-glucose + 2,3-bis-O-geranygeranyl-sn-glycerol
UDP + ?
show the reaction diagram
UDP-alpha-D-glucose + archaeol
UDP + 1,2-bis-phytanyl-sn-glycero-3-O-beta-D-glucoside
show the reaction diagram
UDP-alpha-D-glucose + caldarchaeol
UDP + 1,2-bis-phytanylphytanyl-sn-glycero-3-O-beta-D-glucoside
show the reaction diagram
UDP-alpha-D-glucose + caldarchaetidylinositol
UDP + beta-D-glucosyl caldarchaetidylinositol
show the reaction diagram
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about 90% of the activity compared to archaeol
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-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-glucose + archaeol
UDP + 1,2-bis-phytanyl-sn-glycero-3-O-beta-D-glucoside
show the reaction diagram
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
K+
-
stimulates, maximum activity at 0.5 M
additional information
-
enzyme does not require Mg2+
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-archaetidyl-1D-myo-inositol
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addition of archaetidylinositol is essential
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.8 - 8.9
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pH 6.8: about 45% of maximal activity, pH 8.9: about 80% of maximal activity
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
additional information