Reference on EC 2.4.1.38 - beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Paquet, M.R.; Moscarello, M.A.
A kinetic comparison of partially purified rat liver Golgi and rat serum galactosyltransferases
Biochem. J.
218
745-751
1984
Bos taurus, Rattus norvegicus
Ramakrishnan, B.; Qasba, P.K.
Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I
J. Mol. Biol.
310
205-218
2001
Bos taurus
Blanken, W.M.; van den Eijnden, D.H.
Biosynthesis of terminal Gal alpha (1-3)Gal beta 1-4)GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide alpha(1-3)galactosyltransferase from calf thymus
J. Biol. Chem.
260
12927-12934
1985
Bos taurus
Smith, C.A.; Brew, K.
Isolation and characteristics of galactosyltransferase from Golgi membranes of lactating sheep mammary glands
J. Biol. Chem.
252
7294-7299
1977
Ovis aries
Helting, T.; Erbing, B.
Galactosyltransfer in mouse mastocytoma: purification and properties of N-acetyllactosamine synthetase
Biochim. Biophys. Acta
293
94-104
1973
Mus musculus
Schachter, H.; Jabbal, I.; Hudgin, R.L.; Pinteric, L.
Intracellular localization of liver sugar nucleotide glycoprotein glycosyltransferases in a Golgi-rich fraction
J. Biol. Chem.
245
1090-1100
1970
Rattus norvegicus
Deshmukh, D.S.; Bear, W.D.; Soifer, D.
Isolation and characterization of an enriched Golgi fraction from rat brain
Biochim. Biophys. Acta
542
284-295
1978
Rattus norvegicus
Nakazawa, K.; Furukawa, K.; Kobata, A.; Narimatsu, H.
Characterization of a murine beta 1-4 galactosyltransferase expressed in COS-1 cells
Eur. J. Biochem.
196
363-368
1991
Mus musculus
Nakazawa, K.; Ando, T.; Kimura, T.; Narimatsu, H.
Cloning and sequencing of a full-length cDNA of mouse N-acetylglucosamine (beta 1-4)galactosyltransferase
J. Biochem.
104
165-168
1988
Mus musculus
Shaper, N.L.; Hollis, G.F.; Douglas, J.G.; Kirsch, I.R.; Shaper, J.H.
Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5-end predict two translational start sites at two in-frame AUGs
J. Biol. Chem.
263
10420-10428
1988
Mus musculus
Shaper, N.L.; Shaper, J.H.; Meuth, J.L.; Fox, J.L.; Chang, H.; Kirsch, I.R.; Hollis, G.F.
Bovine galactosyltransferase: identification of a clone by direct immunological screening of a cDNA expression library
Proc. Natl. Acad. Sci. USA
83
1573-1577
1986
Bos taurus
Shaper, N.L.; Wright, W.W.; Shaper, J.H.
Murine beta 1,4-galactosyltransferase: both the amounts and structure of the mRNA are regulated during spermatogenesis
Proc. Natl. Acad. Sci. USA
87
791-795
1990
Mus musculus
Narimatsu, H.; Sinha, S.; Brew, K.; Okayama, H.; Qasba, P.K.
Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase
Proc. Natl. Acad. Sci. USA
83
4720-4724
1986
Bos taurus
Watzele, G.; Berger, E.G.
Near identity of HeLa cell galactosyltransferase with the human placental enzyme
Nucleic Acids Res.
18
7174
1990
Homo sapiens
Amano, J.; Straehl, P.; Berger, E.G.; Kochibe, N.; Kobata, A.
Structures of mucin-type sugar chains of the galactosyltransferase purified from human milk. Occurrence of the ABO and Lewis blood group determinants
J. Biol. Chem.
266
11461-11477
1991
Homo sapiens
Yadav, S.; Brew, K.
Identification of a region of UDP-galactose:N-acetylglucosamine beta 4-galactosyltransferase involved in UDP-galactose binding by differential labeling
J. Biol. Chem.
265
14163-14169
1990
Bos taurus
D'Agostaro, G.; Bendiak, B.; Tropak, M.
Cloning of cDNA encoding the membrane-bound form of bovine beta 1,4-galactosyltransferase
Eur. J. Biochem.
183
211-217
1989
Bos taurus
Hollis, G.F.; Douglas, J.G.; Shaper, N.L.; Shaper, J.H.; Stafford-Hollis, J.M.; Evans, R.J.; Kirsch, I.R.
Genomic structure of murine beta-1,4-galactosyltransferase
Biochem. Biophys. Res. Commun.
162
1069-1075
1989
Mus musculus
Mengle-Gaw, L.; McCoy-Haman, M.F.; Tiemeier, D.C.
Genomic structure and expression of human beta-1,4-galactosyltransferase
Biochem. Biophys. Res. Commun.
176
1269-1276
1991
Homo sapiens
Krezdorn, C.H.; Watzele, G.; Kleene, R.B.; Ivanov, S.X.; Berger, E.G.
Purification and characterization of recombinant human beta 1-4 galactosyltransferase expressed in Saccharomyces cerevisiae
Eur. J. Biochem.
212
113-120
1993
Homo sapiens
Kawano, J.i.; Oinuma, T.; Nakayama, T.; Suganuma, T.
Characterization of beta 1->4 galactosyltransferase purified from rat liver microsomes
J. Biochem.
111
568-572
1992
Rattus norvegicus
Bendiak, B.; Ward, L.D.; Simpson, R.J.
Proteins of the Golgi apparatus. Purification to homogeneity, N-terminal sequence, and unusually large Stokes radius of the membrane-bound form of UDP-galactose:N-acetylglucosamine beta 1-4galactosyltransferase from rat liver
Eur. J. Biochem.
216
405-417
1993
Rattus norvegicus
Mitranic, M.M.; Moscarello, M.A.
The influence of various lipids on the activity of bovine milk galactosyltransferase
Can. J. Biochem.
58
809-814
1980
Bos taurus
Weiser, M.M.; Majumdar, S.; Wilson, J.R.; Luther, R.
Distribution, purification and characterization of rat intestinal UDPgalactose: N-acetylglucosaminyl(beta 1->4)galactosyltransferase
Biochim. Biophys. Acta
924
323-331
1987
Rattus norvegicus
Clark, P.E.; Moscarello, M.A.
The modulating effects of lipids on purified rat liver Golgi galactosyltransferase
Biochim. Biophys. Acta
859
143-150
1986
Rattus norvegicus
Paquet, M.R.; Narasimhan, S.; Schachter, H.; Moscarello, M.A.
Branch specificity of purified rat liver Golgi UDP-galactose: N-acetylglucosamine beta-1,4-galactosyltransferase. Preferential transfer of of galactose on the GlcNAc beta 1,2-Man alpha 1,3-branch of a complex biantennary Asn-linked oligosaccharide
J. Biol. Chem.
259
4716-4721
1984
Rattus norvegicus
Russo, R.N.; Shaper, N.L.; Taatjes, D.J.; Shaper, J.H.
Beta 1,4-galactosyltransferase: a short NH2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention
J. Biol. Chem.
267
9241-9247
1992
Bos taurus
Blanken, W.M.; Hooghwinkel, G.J.M.; van den Eijnden, D.H.
Biosynthesis of blood-group I and i substances. Specificity of bovine colostrum beta-N-acetyl-D-glucosaminide beta 1-4 galactosyltransferase
Eur. J. Biochem.
127
547-552
1982
Bos taurus
Berger, E.G.; Kozdrowski, I.; Weiser, M.M.; van den Eijnden, D.H.; Schiphorst, W.E.C.M.
Human serum galactosyltransferase: distinction, separation and product identification of two galactosyltransferase activities
Eur. J. Biochem.
90
213-222
1978
Homo sapiens
Rao, G.J.S.; Chyatte, D.; Nadler, H.L.
Enhancement of UDPgalactose: glycoprotein galactosyltransferase in cultured human skin fibroblasts by cationic polypeptides
Biochim. Biophys. Acta
541
435-443
1978
Homo sapiens
Fraser, I.H.; Wadden, P.; Mookerjea, S.
Purification and stabilization of galactosyltransferase from serum and lysolecithin extracted microsomes
Can. J. Biochem.
58
878-884
1980
Rattus norvegicus
Bouchilloux, S.
Purification by affinity chromatography and some properties of microsomal galactosyltransferase from pig thyroid
Biochim. Biophys. Acta
569
135-144
1979
Sus scrofa
Tsopanakis, A.D.; Herries, D.G.
Bovine galactosyl transferase. Substrate.managanese complexes and the role of manganese ions in the mechanism
Eur. J. Biochem.
83
179-188
1978
Bos taurus
Andree, P.J.; Berliner, L.J.
Metal ion and substrate binding to bovine galactosyltransferase
Biochemistry
19
929-934
1980
Bos taurus
Cummings, R.D.; Cebula, T.A.; Roth, S.
Characterization of a galactosyltransferase in plasma membrane-enriched fractions from Balb/c 3T12 cells
J. Biol. Chem.
254
1233-1240
1979
Mus musculus
Christner, J.E.; Distler, J.J.; Jourdian, G.W.
Biosynthesis of keratan sulfate: purification and properties of a galactosyltransferase from bovine cornea
Arch. Biochem. Biophys.
192
548-558
1979
Bos taurus
Fleischer, B.; Smigel, M.
Solubilization and properties of galactosyltransferase and sulfotransferase activities of Golgi membranes in Triton X-100
J. Biol. Chem.
253
1632-1638
1978
Rattus norvegicus
Tengowski, M.W.; Wassler, M.J.; Shur, B.D.; Schatten, G.
Subcellular localization of beta1,4-galactosyltransferase on bull sperm and its function during sperm-egg interactions
Mol. Reprod. Dev.
58
236-244
2001
Bos taurus
Bella, A.; Whitehead, J.S.; Kim, Y.S.
Human plasma uridine diphosphate galactose-glycoprotein galactosyltransfertase. Purification, properties and kinetics of the enzyme-catalysed reaction
Biochem. J.
167
621-628
1977
Homo sapiens
Fraser, I.H.; Mookerjea, S.
Purification of membrane-bound galactosyltransferase from rat liver microsomal fractions
Biochem. J.
164
541-547
1977
Rattus norvegicus
Rao, A.K.; Garver, F.; Mendicino, J.
Biosynthesis of the carbohydrate units of immunoglobulins. 1. Purification and properties of galactosyltransferases from swine mesentary lymph nodes
Biochemistry
15
5001-5009
1976
Sus scrofa
Chandler, D.K.; Silvia, J.C.; Ebner, K.E.
Inactivation of galactosyltransferase by lactoperoxidase and N-acetylimidazole
Biochim. Biophys. Acta
616
179-187
1980
Bos taurus
Nelson, J.D.; Jato-Rodriguez, J.J.; Mookerjea, S.
The occurrence and properties of soluble UDP-galactose:glycoprotein galactosyltransferase in human amniotic fluid
Can. J. Biochem.
52
42-50
1974
Homo sapiens, Rattus norvegicus
Wagner, R.R.; Cynkin, M.A.
Glycoprotein metabolism: a UDP-galactose-glycoprotein galactosyltransferase of rat serum
Biochem. Biophys. Res. Commun.
45
57-62
1971
Rattus norvegicus
Fraser, I.H.; Mookerjea, S.
Studies on the purification and properties of UDP-galactose glycoprotein galactosyltransferase from rat liver and serum
Biochem. J.
156
347-355
1976
Rattus norvegicus
Kitchen, B.J.; Andrews, P.
Kinetic studies on the effect of uridine diphosphate galactose and manganous ions on the reaction between lactose synthetase A protein from human milk and p-hydroxymercuribenzoate
Biochem. J.
143
587-590
1974
Homo sapiens
Ramakrishnan, B.; Shah, P.S.; Qasba, P.K.
alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta4Gal-T1*LA complex with UDP-Glc
J. Biol. Chem.
276
37665-37671
2001
Bos taurus
Nguyen, T.T.M.; Hinton, D.A.; Shur, B.D.
Expressing murine beta1,4-galactosyltransferase in HeLa cells produces a cell surface galactosyltransferase-dependent phenotype
J. Biol. Chem.
269
28000-28009
1994
Mus musculus
Nakazawa, K.; Furukawa, K.; Narimatsu, H.; Kobata, A.
Kinetic study of human beta-1,4-galactosyltransferase expressed in E. coli
J. Biochem.
113
747-753
1993
Homo sapiens
Gebhardt, S.; Bihler, S.; Schubert-Zsilaveez, M.; Riva, S.; Monti, D.; Falcone, L.; Danieli, B.
Biocatalytic generation of molecular diversity: modification of ginsenoside Rb1 by beta-1,4-galactosyltransferase and Candida antarctica lipase
Helv. Chim. Acta
85
1943-1959
2002
Bos taurus
-
Uehara, K.; Muramatsu, T.
Molecular cloning and characterization of beta-1,4-galactosyltransferase expressed in mouse testis
Eur. J. Biochem.
244
706-712
1997
Mus musculus
Sato, T.; Furukawa, K.; Bakker, H.; Van den Eijnden, D.H.; Van Die, I.
Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal: GlcNAc beta-1,4-galactosyltransferase
Proc. Natl. Acad. Sci. USA
95
472-477
1998
Homo sapiens (O43286)
Hollister, J.R.; Shaper, J.H.; Jarvis, D.L.
Stable expression of mammalian beta1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells
Glycobiology
8
473-480
1998
Bos taurus
Hansske, B.; Thiel, C.; Lubke, T.; Hasilik, M.; Honing, S.; Peters, V.; Heidemann, P.H.; Hoffmann, G.F.; Berger, E.G.; Von Figura, K.; Korner, C.
Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId
J. Clin. Invest.
109
725-733
2002
Homo sapiens
Ramakrishnan, B.; Qasba, P.K.
Structure-based design of beta 1,4-galactosyltransferase I (beta4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity
J. Biol. Chem.
277
20833-20839
2002
Bos taurus
Herrmann, G.F.; Elling, L.; Krezdorn, C.H.; Kleene, R.; Berger, E.G.; Wandrey, C.
Use of transformed whole yeast cells expressing beta-1,4-galactosyltransferase for the synthesis of N-acetyllactosamine
Bioorg. Med. Chem. Lett.
5
673-676
1995
Bos taurus, Homo sapiens
-
Elling, L.; Zervosen, A.; Gallego, R.G.; Nieder, V.; Malissard, M.; Berger, E.G.; Vliegenthart, J.F.G.; Kamerling, J.P.
UDP-N-acetyl-alpha-D-glucosamine as acceptor substrate of beta-1,4-galactosyltransferase. Enzymatic synthesis of UDP-N-acetyllactosamine
Glycoconjugate J.
16
327-336
1999
Homo sapiens
Snow, D.M.; Shaper, J.H.; Shaper, N.L.; Hart, G.W.
Determination of beta1,4-galactosyltransferase enzymatic activity by capillary electrophoresis and laser-induced fluorescence detection
Anal. Biochem.
271
36-42
1999
Bos taurus
Gastinel, L.N.; Cambillau, C.; Bourne, Y.
Crystal structures of the bovine beta4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose
EMBO J.
18
3546-3557
1999
Bos taurus
Kawano, J.I.; Ide, S.; Oinuma, T.; Suganuma, T.
Regional distribution of beta1-4 galactosyltransferase in rat epididymis
Acta Histochem. Cytochem.
30
491-495
1997
Rattus norvegicus
-
Boeggeman, E.E.; Balajai, P.V.; Qasba, P.K.
Functional domains of bovine beta-1,4-galactosyltransferase
Glycoconjugate J.
12
865-878
1995
Bos taurus
Nishida, Y.; Tamakoshi, H.; Kitagawa, Y.; Kobayashi, K.; Thiem, J.
A novel bovine beta-1,4-galactosyltransferase reaction to yield beta-D-galactopyranosyl-(1-3)-linked disaccharides from L-sugars
Angew. Chem.
39
2000-2003
2000
Bos taurus
Malissard, M.; Borsig, L.; Di Marco, S.; Gruetter, M.G.; Kragl, U.; Wandrey, C.; Berger, E.G.
Recombinant soluble beta-1,4-galactosyltransferases expressed in Saccharomyces cerevisiae. Purification, characterization and comparison with human enzyme
Eur. J. Biochem.
239
340-348
1996
Homo sapiens
Park, J.E.; Lee, K.Y.; Do, S.I.; Lee, S.S.
Expression and characterization of beta-1,4-galactosyltransferase from Neisseria meningitidis and Neisseria gonorrhoeae
J. Biochem. Mol. Biol.
35
330-336
2002
Neisseria gonorrhoeae, Neisseria meningitidis
Boeggeman, E.; Qasba, P.K.
Studies on the metal binding sites in the catalytic domain of beta1,4-galactosyltransferase
Glycobiology
12
395-407
2002
Bos taurus
Zhu, X.; Chen, S.; Yin, X.; Shen, A.; Ji, S.; Shen, Z.; Gu, J.
Constitutively active PKB/Akt inhibited apoptosis and down-regulated beta1,4-galactosyltransferase 1 in hepatocarcinoma cells
Biochem. Biophys. Res. Commun.
309
279-285
2003
Homo sapiens
Ramakrishnan, B.; Boeggeman, E.; Qasba, P.K.
Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I
Biochemistry
44
3202-3210
2005
Bos taurus
Nanthakumar, N.N.; Dai, D.; Meng, D.; Chaudry, N.; Newburg, D.S.; Walker, W.A.
Regulation of intestinal ontogeny: Effect of glucocorticoids and luminal microbes on galactosyltransferase and trehalase induction in mice
Glycobiology
15
221-232
2005
Mus musculus
Zhu, X.; Jiang, J.; Shen, H.; Wang, H.; Zong, H.; Li, Z.; Yang, Y.; Niu, Z.; Liu, W.; Chen, X.; Hu, Y.; Gu, J.
Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells: Identification of E1AF as important transcription activator
J. Biol. Chem.
280
12503-12516
2005
Homo sapiens
Zhu, D.; Shen, A.; Sun, M.; Gu, J.
Distinct patterns of expression of the beta-1,4-galactosyltransferases during testicular development in the mouse
Mol. Cell. Biochem.
247
147-153
2003
Mus musculus
Boeggeman, E.E.; Ramakrishnan, B.; Qasba, P.K.
The N-terminal stem region of bovine and human beta1,4-galactosyltransferase I increases the in vitro folding efficiency of their catalytic domain from inclusion bodies
Protein Expr. Purif.
30
219-229
2003
Bos taurus, Homo sapiens
Li, Z.; Wang, H.; Zong, H.; Sun, Q.; Kong, X.; Jiang, J.; Gu, J.
Downregulation of beta1,4-galactosyltransferase 1 inhibits CDK11(p58)-mediated apoptosis induced by cycloheximide
Biochem. Biophys. Res. Commun.
327
628-636
2005
Homo sapiens
Menzies, K.K.; Nicholas, K.R.
The expression of beta-1,3 galactosyltransferase and beta-1,4 galactosyltransferase enzymatic activities in the mammary gland of the tammar wallaby (Macropus eugenii) during early lactation
Biochim. Biophys. Acta
1770
115-120
2007
Notamacropus eugenii
Boeggeman, E.; Ramakrishnan, B.; Kilgore, C.; Khidekel, N.; Hsieh-Wilson, L.C.; Simpson, J.T.; Qasba, P.K.
Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method
Bioconjug. Chem.
18
806-814
2007
Homo sapiens
Chen, W.S.; Chang, H.Y.; Li, C.P.; Liu, J.M.; Huang, T.S.
Tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis
Clin. Cancer Res.
11
8615-8622
2005
Homo sapiens
Machingo, Q.J.; Fritz, A.; Shur, B.D.
A beta1,4-galactosyltransferase is required for convergent extension movements in zebrafish
Dev. Biol.
297
471-482
2006
Danio rerio
Brockhausen, I.; Benn, M.; Bhat, S.; Marone, S.; Riley, J.G.; Montoya-Peleaz, P.; Vlahakis, J.Z.; Paulsen, H.; Schutzbach, J.S.; Szarek, W.A.
UDP-Gal: GlcNAc-R beta1,4-galactosyltransferase - a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme
Glycoconj. J.
23
525-541
2006
Bos taurus
Jiang, J.; Chen, X.; Shen, J.; Wei, Y.; Wu, T.; Yang, Y.; Wang, H.; Zong, H.; Yang, J.; Zhang, S.; Xie, J.; Kong, X.; Liu, W.; Gu, J.
beta1,4-Galactosyltransferase V functions as a positive growth regulator in glioma
J. Biol. Chem.
281
9482-9489
2006
Homo sapiens
Takaya, K.; Nagahori, N.; Kurogochi, M.; Furuike, T.; Miura, N.; Monde, K.; Lee, Y.C.; Nishimura, S.
Rational design, synthesis, and characterization of novel inhibitors for human beta1,4-galactosyltransferase
J. Med. Chem.
48
6054-6065
2005
Homo sapiens
Ramasamy, V.; Ramakrishnan, B.; Boeggeman, E.; Ratner, D.M.; Seeberger, P.H.; Qasba, P.K.
Oligosaccharide preferences of beta1,4-galactosyltransferase-I: crystal structures of Met340His mutant of human beta1,4-galactosyltransferase-I with a pentasaccharide and trisaccharides of the N-glycan moiety
J. Mol. Biol.
353
53-67
2005
Homo sapiens (P15291)
Ramakrishnan, B.; Ramasamy, V.; Qasba, P.K.
Structural snapshots of beta-1,4-galactosyltransferase-I along the kinetic pathway
J. Mol. Biol.
357
1619-1633
2006
Bos taurus, Homo sapiens
Ramakrishnan, B.; Qasba, P.K.
Role of a single amino acid in the evolution of glycans of invertebrates and vertebrates
J. Mol. Biol.
365
570-576
2007
Homo sapiens
Pisvejcova, A.; Rossi, C.; Husakova, L.; Kren, V.; Riva, S.; Monti, D.
beta-1,4-Galactosyltransferase-catalyzed glycosylation of sugar derivatives: Modulation of the enzyme activity by alpha-lactalbumin, immobilization and solvent tolerance
J. Mol. Catal. B
39
98-104
2006
Bos taurus
-
Chen, P.; Harcum, S.W.
Effects of elevated ammonium on glycosylation gene expression in CHO cells
Metab. Eng.
8
123-132
2006
Cricetulus griseus (Q99PC2)
Li, Z.; Zong, H.; Kong, X.; Zhang, S.; Wang, H.; Sun, Q.; Gu, J.
Cell surface beta 1, 4-galactosyltransferase 1 promotes apoptosis by inhibiting epidermal growth factor receptor pathway
Mol. Cell. Biochem.
291
69-76
2006
Homo sapiens
Rhee, S.W.; Starr, T.; Forsten-Williams, K.; Storrie, B.
The steady-state distribution of glycosyltransferases between the Golgi apparatus and the endoplasmic reticulum is approximately 90:10
Traffic
6
978-990
2005
Homo sapiens
Fujiyama, K.; Furukawa, A.; Katsura, A.; Misaki, R.; Omasa, T.; Seki, T.
Production of mouse monoclonal antibody with galactose-extended sugar chain by suspension cultured tobacco BY2 cells expressing human beta(1,4)-galactosyltransferase
Biochem. Biophys. Res. Commun.
358
85-91
2007
Homo sapiens
Chang, K.H.; Lee, J.M.; Hwang-Bo, J.; Yoo, K.H.; Sohn, B.H.; Yang, J.M.; Chung, I.S.
Expression of recombinant cyclooxygenase 1 in Drosophila melanogaster S2 cells transformed with human beta1,4-galactosyltransferase and Galbeta1,4-GlcNAc alpha2,6-sialyltransferase
Biotechnol. Lett.
29
1803-1809
2007
Homo sapiens
Wei, Y.; Liu, D.; Ge, Y.; Zhou, F.; Xu, J.; Chen, H.; Yun, X.; Gu, J.; Jiang, J.
Down-regulation of beta 1,4GalT V at protein level contributes to arsenic trioxide-induced glioma cell apoptosis
Cancer Lett.
267
96-105
2008
Homo sapiens
Namdjou, D.J.; Chen, H.M.; Vinogradov, E.; Brochu, D.; Withers, S.G.; Wakarchuk, W.W.
A beta-1,4-galactosyltransferase from Helicobacter pylori is an efficient and versatile biocatalyst displaying a novel activity for thioglycoside synthesis
Chembiochem
9
1632-1640
2008
Helicobacter pylori, Neisseria meningitidis
Qasba, P.K.; Ramakrishnan, B.; Boeggeman, E.
Structure and function of beta-1,4-galactosyltransferase
Curr. Drug Targets
9
292-309
2008
Drosophila melanogaster, Homo sapiens
Dabros, W.; Kordowiak, A.
Comparison of bipyridyl, maltol and kojic acid action as organic vanadium ligands on activity of galactosyltransferase (EC 2.4.1.38), some physiological parameters and ultrastructure of Golgi complexes in rat hepatocytes
Folia Histochem. Cytobiol.
45
239-244
2007
Rattus norvegicus
Bhaumik, S.K.; Singh, M.; Basu, R.; Bhaumik, S.; Roychoudhury, K.; Naskar, K.; Roy, S.; De, T.
Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote
Glycoconj. J.
25
459-472
2008
Leishmania donovani (A9XBL4), Leishmania donovani UR6 (A9XBL4)
Qian, J.; Cheng, C.; Liu, H.; Chen, J.; Yan, M.; Niu, S.; Qin, J.; Sun, L.; Liu, L.; Gu, J.; Shen, A.
Expression of beta-1,4-galactosyltransferase-I in rat during inflammation
Inflammation
30
59-68
2007
Rattus norvegicus
Zhou, J.; Wei, Y.; Liu, D.; Ge, X.; Zhou, F.; Yun, X.; Jiang, J.; Gu, J.
Identification of beta 1,4GalT II as a target gene of p53-mediated HeLa cell apoptosis
J. Biochem.
143
547-554
2008
Homo sapiens
Yan, M.; Xia, C.; Niu, S.; Shao, X.; Cheng, C.; Zhao, J.; Shen, A.
The role of TNF-alpha and its receptors in the production of beta-1,4 galactosyltransferase I and V mRNAs by rat primary astrocytes
J. Mol. Neurosci.
33
155-162
2007
Rattus norvegicus, Rattus norvegicus (P80225)
Shen, J.; Jiang, J.; Wei, Y.; Zhou, L.; Liu, D.; Zhou, J.; Gu, J.
Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis
Mol. Cell. Biochem.
304
361-367
2007
Homo sapiens
Daligault, F.; Rahuel-Clermont, S.; Gulberti, S.; Cung, M.T.; Branlant, G.; Netter, P.; Magdalou, J.; Lattard, V.
Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7
Biochem. J.
418
605-614
2009
Homo sapiens
Brockhausen, I.; Dowler, T.; Paulsen, H.
Site directed processing: role of amino acid sequences and glycosylation of acceptor glycopeptides in the assembly of extended mucin type O-glycan core 2
Biochim. Biophys. Acta
1790
1244-1257
2009
Bos taurus, Homo sapiens (O60909)
Lee, P.L.; Kohler, J.J.; Pfeffer, S.R.
Association of beta-1,3-N-acetylglucosaminyltransferase 1 and beta-1,4-galactosyltransferase 1, trans-Golgi enzymes involved in coupled poly-N-acetyllactosamine synthesis
Glycobiology
19
655-664
2009
Homo sapiens
Yang, H.; Hu, L.; Chen, J.; Zhu, J.; Tao, T.; Zhang, F.; Li, X.; He, X.; Shen, A.; Cheng, C.
Lipopolysaccharide induced upregulation of beta-1,4-galactosyltransferase-I in Schwann cell
Inflammation
32
279-286
2009
Rattus norvegicus
Brown, J.R.; Yang, F.; Sinha, A.; Ramakrishnan, B.; Tor, Y.; Qasba, P.K.; Esko, J.D.
Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis
J. Biol. Chem.
284
4952-4959
2009
Homo sapiens (P15291)
Krupicka, M.; Tvaroska, I.
Hybrid quantum mechanical/molecular mechanical investigation of the beta-1,4-galactosyltransferase-I mechanism
J. Phys. Chem. B
113
11314-11319
2009
Bos taurus
Mugnier, S.; Boittin, S.; Douet, C.; Monget, P.; Magistrini, M.; Goudet, G.
The involvement of beta-1,4-galactosyltransferase and N-acetylglucosamine residues in fertilization has been lost in the horse
Reprod. Biol. Endocrinol.
6
51
2008
Equus caballus
Wei, Y.; Zhou, F.; Ge, Y.; Chen, H.; Cui, C.; Li, Q.; Liu, D.; Yang, Z.; Wu, G.; Sun, S.; Gu, J.; Jiang, J.
beta1,4-galactosyltransferase V regulates self-renewal of glioma-initiating cell
Biochem. Biophys. Res. Commun.
396
602-607
2010
Homo sapiens
Choi, H.J.; Chung, T.W.; Kim, C.H.; Jeong, H.S.; Joo, M.; Youn, B.; Ha, K.T.
Estrogen induced beta-1,4-galactosyltransferase 1 expression regulates proliferation of human breast cancer MCF-7 cells
Biochem. Biophys. Res. Commun.
426
620-625
2012
Homo sapiens
Cheng, X.; Wang, X.; Han, Y.; Wu, Y.
The expression and function of beta-1,4-galactosyltransferase-I in dendritic cells
Cell. Immunol.
266
32-39
2010
Homo sapiens
Wang, H.; Xu, D.; Tao, R.; Ni, X.; Shen, A.; Wang, Y.
Beta-1,4-galactosyltransferase-I in synovial tissue of collagen-induced rat model of rheumatoid arthritis
Clin. Exp. Med.
11
147-154
2011
Rattus norvegicus
Peanne, R.; Legrand, D.; Duvet, S.; Mir, A.M.; Matthijs, G.; Rohrer, J.; Foulquier, F.
Differential effects of lobe A and lobe B of the Conserved Oligomeric Golgi complex on the stability of (beta)1,4-galactosyltransferase 1 and (alpha)2,6-sialyltransferase 1
Glycobiology
21
864-876
2011
Homo sapiens
Zhu, F.; Shen, F.; Fan, Y.; Xie, Y.; Xia, Y.; Kong, Y.
Osteopontin increases the expression of beta1, 4-galactosyltransferase-I and promotes adhesion in human RL95-2 cells
Glycoconj. J.
29
347-356
2012
Homo sapiens, Mus musculus
Wang, Y.; Xu, D.; Tao, R.; Wang, H.; Wang, Q.; Shen, A.
beta1,4-Galactosyltransferase-I contributes to the inflammatory processes in synovial tissue of patients with rheumatoid arthritis
Inflamm. Res.
59
1009-1018
2010
Homo sapiens
Liu, X.; Cheng, C.; Shao, B.; Wu, X.; Ji, Y.; Lu, X.; Shen, A.
The functional interaction between CDK11p58 and beta-1,4-galactosyltransferase I involved in astrocyte activation caused by lipopolysaccharide
Inflammation
35
1365-1377
2012
Rattus norvegicus
Liu, W.; Cui, Z.; Wang, Y.; Zhu, X.; Fan, J.; Bao, G.; Qiu, J.; Xu, D.
Elevated expression of beta 1,4-galactosyltransferase-I in cartilage and synovial tissue of patients with osteoarthritis
Inflammation
35
647-655
2012
Homo sapiens
Kouno, T.; Kizuka, Y.; Nakagawa, N.; Yoshihara, T.; Asano, M.; Oka, S.
Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate
J. Biol. Chem.
286
31337-31346
2011
Homo sapiens
Yang, H.; Yuan, Q.; Chen, Q.; Li, C.; Wu, X.; Peng, C.; Kang, L.; Lu, X.; Sun, H.; Zhou, Z.; Shen, A.; Cheng, C.
beta-1,4-galactosyltransferase I promotes tumor necrosis factor-alpha autocrine via the activation of MAP kinase signal pathways in Schwann cells
J. Mol. Neurosci.
45
269-276
2011
Rattus norvegicus
Yuan, Q.; Yang, H.; Cheng, C.; Li, C.; Wu, X.; Huan, W.; Sun, H.; Zhou, Z.; Wang, Y.; Zhao, Y.; Lu, X.; Shen, A.
beta-1,4-Galactosyltransferase I involved in Schwann cells proliferation and apoptosis induced by tumor necrosis factor-alpha via the activation of MAP kinases signal pathways
Mol. Cell. Biochem.
365
149-158
2012
Rattus norvegicus
Tang, W.; Weng, S.; Zhang, S.; Wu, W.; Dong, L.; Shen, X.; Zhang, S.; Gu, J.; Xue, R.
Direct interaction between surface beta1,4-galactosyltransferase 1 and epidermal growth factor receptor (EGFR) inhibits EGFR activation in hepatocellular carcinoma
Biochem. Biophys. Res. Commun.
434
449-454
2013
Homo sapiens
Jiang, J.; Kanabar, V.; Padilla, B.; Man, F.; Pitchford, S.C.; Page, C.P.; Wagner, G.K.
Uncharged nucleoside inhibitors of beta-1,4-galactosyltransferase with activity in cells
Chem. Commun. (Camb.)
52
3955-3958
2016
Homo sapiens
Tokuda, N.; Numata, S.; Li, X.; Nomura, T.; Takizawa, M.; Kondo, Y.; Yamashita, Y.; Hashimoto, N.; Kiyono, T.; Urano, T.; Furukawa, K.; Furukawa, K.
beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5
Glycobiology
23
1175-1183
2013
Mus musculus
Tsutsui, Y.; Ramakrishnan, B.; Qasba, P.K.
Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding
J. Biol. Chem.
288
31963-31970
2013
Homo sapiens (Q9UBV7)
Saliba, M.; Ramalanjaona, N.; Gulberti, S.; Bertin-Jung, I.; Thomas, A.; Dahbi, S.; Lopin-Bon, C.; Jacquinet, J.C.; Breton, C.; Ouzzine, M.; Fournel-Gigleux, S.
Probing the acceptor active site organization of the human recombinant beta1,4-galactosyltransferase 7 and design of xyloside-based inhibitors
J. Biol. Chem.
290
7658-7670
2015
Homo sapiens (Q9UBV7)
Geisler, C.; Mabashi-Asazuma, H.; Kuo, C.W.; Khoo, K.H.; Jarvis, D.L.
Engineering beta1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells
J. Biotechnol.
193
52-65
2015
Bos taurus (P08037)
Hesselink, T.; Rouwendal, G.J.; Henquet, M.G.; Florack, D.E.; Helsper, J.P.; Bosch, D.
Expression of natural human beta1,4-GalT1 variants and of non-mammalian homologues in plants leads to differences in galactosylation of N-glycans
Transgenic Res.
23
717-728
2014
Danio rerio (C1KH59), Homo sapiens (P15291), Gallus gallus (Q92074)
Li, Y.; Xue, M.; Sheng, X.; Yu, H.; Zeng, J.; Thon, V.; Chen, Y.; Muthana, M.; Wang, P.; Chen, X.
Donor substrate promiscuity of bacterial beta1-3-N-acetylglucosaminyltransferases and acceptor substrate flexibility of beta1-4-galactosyltransferases
Bioorg. Med. Chem.
24
1696-1705
2016
Bos taurus, Helicobacter pylori, Neisseria meningitidis
Huang, K.; Parmeggiani, F.; Ledru, H.; Hollingsworth, K.; Mas Pons, J.; Marchesi, A.; Both, P.; Mattey, A.P.; Pallister, E.; Bulmer, G.S.; van Munster, J.M.; Turnbull, W.B.; Galan, M.C.; Flitsch, S.L.
Enzymatic synthesis of N-acetyllactosamine from lactose enabled by recombinant beta1,4-galactosyltransferases
Org. Biomol. Chem.
17
5920-5924
2019
Neisseria meningitidis serogroup A (P57033), Neisseria meningitidis (Q2TIJ3), Neisseria meningitidis serogroup B (Q51116), Neisseria meningitidis serogroup A Z2491 (P57033), Neisseria meningitidis serogroup B MC58 (Q51116)
html completed
