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Reference on EC 2.4.1.37 - fucosylgalactoside 3-alpha-galactosyltransferase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Marcus, S.L.; Polakowski, R.; Seto, N.O.L.; Leinala, E.; Borisova, S.; Blancher, A.; Roubinet, F.; Evans, S.V.; Palcic, M.M.
A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase
J. Biol. Chem.
278
12403-12405
2003
Homo sapiens (P16442)
Manually annotated by BRENDA team
Patenaude, S.I.; Seto, N.O.L.; Borisova, S.N.; Szpacenko, A.; Marcus, S.L.; Palcic, M.M.; Evans, S.V.
The structural basis for specificity in human ABO(H) blood group biosynthesis
Nat. Struct. Biol.
9
685-690
2002
Homo sapiens (P16442)
Manually annotated by BRENDA team
Yamamoto, M.; Lin, X.H.; Kominato, Y.; Hata, Y.; Noda, R.; Saitou, N.; Yamamoto, F.
Murine equivalent of the human histo-blood group ABO gene is a cis-AB gene and encodes a glycosyltransferase with both A and B transferase activity
J. Biol. Chem.
276
13701-13708
2001
Mus spicilegus, Mus musculus brevirostris (P38649), Mus musculus castaneus (P38649), Mus musculus domesticus (P38649), Mus musculus brevirostris BFM/2Msf (P38649), Mus spicilegus ZBN, Mus musculus domesticus BALB/c (P38649), Mus musculus castaneus CAST/Ei (P38649)
Manually annotated by BRENDA team
Sujino, K.; Uchiyama, T.; Hindsgaul, O.; Seto, N.O.L.; Wakarchuk, W.W.; Palcic, M.M.
Enzymatic synthesis of oligosaccharide analogues: evaluation of UDP-Gal analogues as donors for three retaining alpha-galactosyltransferases
J. Am. Chem. Soc.
122
1261-1269
2000
Homo sapiens
-
Manually annotated by BRENDA team
Seto, N.O.L.; Compston, C.A.; Szpacenko, A.; Palcic, M.M.
Enzymatic synthesis of blood group A and B trisaccharide analogues
Carbohydr. Res.
324
161-169
2000
Homo sapiens
Manually annotated by BRENDA team
Mukherjee, A.; Palcic, M.M.; Hindsgaul, O.
Synthesis and enzymatic evaluation of modified acceptors of recombinant blood group A and B glycosyltransferases
Carbohydr. Res.
326
1-21
2000
Homo sapiens
Manually annotated by BRENDA team
Kamath, V.P.; Seto, N.O.L.; Compston, C.A.; Hindsgaul, O.; Palcic, M.M.
Synthesis of the acceptor analog alpha-Fuc(1-2)-alpha-Gal-O(CH2)7CH3: a probe for the kinetic mechanism of recombinant human blood group B glycosyltransferase
Glycoconj. J.
16
599-606
2000
Homo sapiens
Manually annotated by BRENDA team
Seto, N.O.; Compston, C.A.; Evans, S.V.; Bundle, D.R.; Narang, S.A.; Palcic, M.M.
Donor substrate specificity of recombinant human blood group A, B and hybrid A/B glycosyltransferases expressed in Escherichia coli
Eur. J. Biochem.
259
770-775
1999
Homo sapiens
Manually annotated by BRENDA team
Yu, L.C.; Lee, H.L.; Chan, Y.S.; Lin, M.
The molecular basis for the B(A) allele: an amino acid alteration in the human histoblood group B alpha-(1,3)-galactosyltransferase increases its intrinsic alpha-(1,3)-N-acetylgalactosaminyltransferase activity
Biochem. Biophys. Res. Commun.
262
487-493
1999
Homo sapiens
Manually annotated by BRENDA team
Seto, N.O.L.; Palcic, M.M.; Compston, C.A.; Li, H.; Bundle, D.R.; Narang, S.A.
Sequential interchange of four amino acids from blood group B to blood group A glycosyltransferase boosts catalytic activity and progressively modifies substrate recognition in human recombinant enzymes
J. Biol. Chem.
272
14133-14138
1997
Homo sapiens
Manually annotated by BRENDA team
Seto, N.O.L.; Palcic, M.M.; Hindsgaul, O.; Bundle, D.R.; Narang, S.A.
Expression of a recombinant human glycosyltransferase from a synthetic gene and its utilization for synthesis of the human blood group B trisaccharide
Eur. J. Biochem.
234
323-328
1995
Homo sapiens
Manually annotated by BRENDA team
Lowary, T.L.; Hindsgaul, O.
Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor alpha-L-Fuc p-(1-2)-beta-D-Gal p-OR by the blood-group A and B gene-specified glycosyltransferases
Carbohydr. Res.
251
33-67
1994
Homo sapiens
Manually annotated by BRENDA team
Nakajima, T.; Furukawa, K.; Takenaka, O.
Blood group A and B glycosyltransferase in nonhuman primate plasma
Exp. Clin. Immunogenet.
10
21-30
1993
Homo sapiens, Hylobates lar entelloides, Macaca fuscata
Manually annotated by BRENDA team
Yazawa, S.; Nakajima, T.; Kameyama, N.; Saga, K.I.; Tachikawa, T.
An enzyme-linked immunosorbent assay for blood-group A and B enzymes
Carbohydr. Res.
239
329-335
1993
Homo sapiens
Manually annotated by BRENDA team
Betteridge, A.; Watkins, W.M.
Two alpha-3-D-galactosyltransferases in rabbit stomach mucosa with different acceptor substrate specificities
Eur. J. Biochem.
132
29-35
1983
Oryctolagus cuniculus
Manually annotated by BRENDA team
Nagai, M.; Dave, V.; Muensch, H.; Yoshida, A.
Human blood group glycosyltransferase. II. Purification of galactosyltransferase
J. Biol. Chem.
253
380-381
1978
Homo sapiens
Manually annotated by BRENDA team
Carne, L.R.; Watkins, W.M.
Human blood group B gene-specified alpha-3-galactosyltransferase: purification of the enzyme in serum by biospecific adsorption onto blood group O erythrocyte membranes
Biochem. Biophys. Res. Commun.
77
700-707
1977
Homo sapiens
Manually annotated by BRENDA team
Race, C.; Zideman, D.; Watkins, W.M.
An alpha-D-galactosyltransferase associated with the blood-group B character
Biochem. J.
107
733-735
1968
Papio sp., Homo sapiens
Manually annotated by BRENDA team
Turcot, A.L.; Blancher, A.; Le Moullac-Vaidye, B.; Despiau, S.; Rocher, J.; Roubinet, F.; Szpirer, C.; Le Pendu, J.
Cloning of a rat gene encoding the histo-blood group B enzyme: rats have more than one Abo gene
Glycobiology
13
919-928
2003
Rattus norvegicus (Q8CFC4)
Manually annotated by BRENDA team
Nguyen, H.P.; Seto, N.O.L.; Cai, Y.; Leinala, E.K.; Borisova, S.N.; Palcic, M.M.; Evans, S.V.
The influence of an intramolecular hydrogen bond in differential recognition of inhibitory acceptor analogs by human ABO(H) blood group A and B glycosyltransferases
J. Biol. Chem.
278
49191-49195
2003
Homo sapiens (P16442)
Manually annotated by BRENDA team
Ketcham, C.; Wang, F.; Fisher, S.Z.; Ercan, A.; van der Wel, H.; Locke, R.D.; Sirajud-Doulah, k.; Matta, K.L.; West, C.M.
Specificity of a soluble UDP-galactose:fucoside alpha1,3-galactosyltransferase that modifies the cytoplasmic glycoprotein Skp1 in Dictyostelium
J. Biol. Chem.
279
29050-29059
2004
Dictyostelium discoideum
Manually annotated by BRENDA team
Yazer, M.H.; Denomme, G.A.; Rose, N.L.; Palcic, M.M.
Amino-acid substitution in the disordered loop of blood group B-glycosyltransferase enzyme causes weak B phenotype
Transfusion
45
1178-1182
2005
Homo sapiens
Manually annotated by BRENDA team
Angulo, J.; Langpap, B.; Blume, A.; Biet, T.; Meyer, B.; Krishna, N.R.; Peters, H.; Palcic, M.M.; Peters, T.
Blood group B galactosyltransferase: insights into substrate binding from NMR experiments
J. Am. Chem. Soc.
128
13529-13538
2006
Homo sapiens (P16442), Homo sapiens
Manually annotated by BRENDA team
Blume, A.; Angulo, J.; Biet, T.; Peters, H.; Benie, A.J.; Palcic, M.; Peters, T.
Fragment-based screening of the donor substrate specificity of human blood group B galactosyltransferase using saturation transfer difference NMR
J. Biol. Chem.
281
32728-32740
2006
Homo sapiens
Manually annotated by BRENDA team
Letts, J.A.; Rose, N.L.; Fang, Y.R.; Barry, C.H.; Borisova, S.N.; Seto, N.O.; Palcic, M.M.; Evans, S.V.
Differential recognition of the type I and II H antigen acceptors by the human ABO(H) blood group A and B glycosyltransferases
J. Biol. Chem.
281
3625-3632
2006
Homo sapiens (P16442)
Manually annotated by BRENDA team
Persson, M.; Letts, J.A.; Hosseini-Maaf, B.; Borisova, S.N.; Palcic, M.M.; Evans, S.V.; Olsson, M.L.
Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif
J. Biol. Chem.
282
9564-9570
2007
Homo sapiens (P16442), Homo sapiens
Manually annotated by BRENDA team
Nakahara, T.; Hindsgaul, O.; Palcic, M.M.; Nishimura, S.
Computational design and experimental evaluation of glycosyltransferase mutants: engineering of a blood type B galactosyltransferase with enhanced glucosyltransferase activity
Protein Eng. Des. Sel.
19
571-578
2006
Homo sapiens (P16442)
Manually annotated by BRENDA team
Letts, J.A.; Persson, M.; Schuman, B.; Borisova, S.N.; Palcic, M.M.; Evans, S.V.
The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B
Acta Crystallogr. Sect. D
63
860-865
2007
Homo sapiens (P16442), Homo sapiens
Manually annotated by BRENDA team
Persson, M.; Palcic, M.M.
A high-throughput pH indicator assay for screening glycosyltransferase saturation mutagenesis libraries
Anal. Biochem.
378
1-7
2008
Homo sapiens
Manually annotated by BRENDA team
Alfaro, J.A.; Zheng, R.B.; Persson, M.; Letts, J.A.; Polakowski, R.; Bai, Y.; Borisova, S.N.; Seto, N.O.; Lowary, T.L.; Palcic, M.M.; Evans, S.V.
ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes
J. Biol. Chem.
283
10097-10108
2008
Homo sapiens (P16442)
Manually annotated by BRENDA team
Hosseini-Maaf, B.; Letts, J.A.; Persson, M.; Smart, E.; LePennec, P.; Hustinx, H.; Zhao, Z.; Palcic, M.M.; Evans, S.V.; Chester, M.A.; Olsson, M.L.
Structural basis for red cell phenotypic changes in newly identified, naturally occurring subgroup mutants of the human blood group B glycosyltransferase
Transfusion
47
864-875
2007
Homo sapiens (A5X6H3), Homo sapiens (A5X6H4), Homo sapiens (A5X6H5), Homo sapiens (A5X6H7), Homo sapiens (A5X6H8), Homo sapiens (Q6L638), Homo sapiens
Manually annotated by BRENDA team
Soya, N.; Shoemaker, G.K.; Palcic, M.M.; Klassen, J.S.
Comparative study of substrate and product binding to the human ABO(H) blood group glycosyltransferases
Glycobiology
19
1224-1234
2009
Homo sapiens
Manually annotated by BRENDA team
Sindhuwinata, N.; Munoz, E.; Munoz, F.J.; Palcic, M.M.; Peters, H.; Peters, T.
Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase
Glycobiology
20
718-723
2010
Homo sapiens
Manually annotated by BRENDA team
Seltsam, A.; Grueger, D.; Just, B.; Figueiredo, C.; Gupta, C.D.; Deluca, D.S.; Blasczyk, R.
Aberrant intracellular trafficking of a variant B glycosyltransferase
Transfusion
48
1898-1905
2008
Homo sapiens (P16442)
Manually annotated by BRENDA team
Yamamoto, F.; Yamamoto, M.; Blancher, A.
Generation of histo-blood group B transferase by replacing the N-acetyl-D-galactosamine recognition domain of human A transferase with the galactose-recognition domain of evolutionarily related murine alpha1,3-galactosyltransferase
Transfusion
50
622-630
2009
Homo sapiens
Manually annotated by BRENDA team
Johal, A.; Schuman, B.; Alfaro, J.; Borisova, S.; Seto, N.; Evans, S.
Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases
Acta Crystallogr. Sect. D
68
268-276
2012
Homo sapiens
Manually annotated by BRENDA team
Adlercreutz, D.; Weadge, J.T.; Petersen, B.O.; Duus, J.; Dovichi, N.J.; Palcic, M.M.
Enzymatic synthesis of Gb3 and iGb3 ceramides
Carbohydr. Res.
345
1384-1388
2010
Homo sapiens
Manually annotated by BRENDA team
Schaefer, K.; Albers, J.; Sindhuwinata, N.; Peters, T.; Meyer, B.
A new concept for glycosyltransferase inhibitors: nonionic mimics of the nucleotide donor of the human blood group B galactosyltransferase
ChemBioChem
13
443-450
2012
Homo sapiens
Manually annotated by BRENDA team
Rademacher, C.; Landstroem, J.; Sindhuwinata, N.; Palcic, M.M.; Widmalm, G.; Peters, T.
NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments
Glycoconj. J.
27
349-358
2010
Homo sapiens
Manually annotated by BRENDA team
Schuman, B.; Persson, M.; Landry, R.C.; Polakowski, R.; Weadge, J.T.; Seto, N.O.; Borisova, S.N.; Palcic, M.M.; Evans, S.V.
Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding
J. Mol. Biol.
402
399-411
2010
Homo sapiens
Manually annotated by BRENDA team
Jorgensen, R.; Batot, G.; Mannerstedt, K.; Imberty, A.; Breton, C.; Hindsgaul, O.; Royant, A.; Palcic, M.M.
Structures of a human blood group glycosyltransferase in complex with a photo-activatable UDP-Gal derivative reveal two different binding conformations
Acta Crystallogr. Sect. F
70
1015-1021
2014
Homo sapiens (P16442)
Manually annotated by BRENDA team
Sindhuwinata, N.; Grimm, L.L.; Weissbach, S.; Zinn, S.; Munoz, E.; Palcic, M.M.; Peters, T.
Thermodynamic signature of substrates and substrate analogs binding to human blood group B galactosyltransferase from isothermal titration calorimetry experiments
Biopolymers
99
784-795
2013
Homo sapiens
Manually annotated by BRENDA team
Johal, A.R.; Blackler, R.J.; Alfaro, J.A.; Schuman, B.; Borisova, S.; Evans, S.V.
pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state
Glycobiology
24
237-246
2014
Homo sapiens (P16442)
Manually annotated by BRENDA team
Gagnon, S.M.; Meloncelli, P.J.; Zheng, R.B.; Haji-Ghassemi, O.; Johal, A.R.; Borisova, S.N.; Lowary, T.L.; Evans, S.V.
High resolution structures of the human ABO(H) blood group enzymes in complex with donor analogs reveal that the enzymes utilize multiple donor conformations to bind substrates in a stepwise manner
J. Biol. Chem.
290
27040-27052
2015
Homo sapiens (P16442)
Manually annotated by BRENDA team
Wagner, G.K.; Pesnot, T.; Palcic, M.M.; Jorgensen, R.
Novel UDP-GalNAc Derivative structures provide insight into the donor specificity of human blood group glycosyltransferase
J. Biol. Chem.
290
31162-31172
2015
Homo sapiens (P16442)
Manually annotated by BRENDA team
Schaefer, K.; Sindhuwinata, N.; Hackl, T.; Koetzler, M.P.; Niemeyer, F.C.; Palcic, M.M.; Peters, T.; Meyer, B.
A nonionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase: design, synthesis, and characterization
J. Med. Chem.
56
2150-2154
2013
Homo sapiens
Manually annotated by BRENDA team
Grimm, L.; Weissbach, S.; Fluegge, F.; Begemann, N.; Palcic, M.; Peters, T.
Protein NMR studies of substrate binding to human blood group A and B glycosyltransferases
ChemBioChem
18
1260-1269
2017
Homo sapiens (P16442)
Manually annotated by BRENDA team
Weissbach, S.; Fluegge, F.; Peters, T.
Substrate binding drives active-site closing of human blood group B balactosyltransferase as revealed by hot-spot labeling and NMR spectroscopy experiments
ChemBioChem
19
970-978
2018
Homo sapiens (P16442), Homo sapiens
Manually annotated by BRENDA team
Fluegge, F.; Peters, T.
Insights into allosteric control of human blood group A and B glycosyltransferases from dynamic NMR
ChemistryOpen
8
760-769
2019
Homo sapiens (P16442)
Manually annotated by BRENDA team
Strecker, C.; Peters, H.; Hackl, T.; Peters, T.; Meyer, B.
Fragment growing to design optimized inhibitors for human blood group B galactosyltransferase (GTB)
ChemMedChem
14
1336-1342
2019
Homo sapiens (P16442), Homo sapiens
Manually annotated by BRENDA team
Blackler, R.J.; Gagnon, S.M.; Polakowski, R.; Rose, N.L.; Zheng, R.B.; Letts, J.A.; Johal, A.R.; Schuman, B.; Borisova, S.N.; Palcic, M.M.; Evans, S.V.
Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site
Glycobiology
27
370-380
2017
Homo sapiens (P16442)
Manually annotated by BRENDA team
Gagnon, S.M.L.; Legg, M.S.G.; Sindhuwinata, N.; Letts, J.A.; Johal, A.R.; Schuman, B.; Borisova, S.N.; Palcic, M.M.; Peters, T.; Evans, S.V.
High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release
Glycobiology
27
966-977
2017
Homo sapiens (P16442)
Manually annotated by BRENDA team
Gagnon, S.; Legg, M.; Polakowski, R.; Letts, J.; Persson, M.; Lin, S.; Zheng, R.; Rempel, B.; Schuman, B.; Haji-Ghassemi, O.; Borisova, S.; Palcic, M.; Evans, S.
Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases
Glycobiology
28
624-636
2018
Homo sapiens (P16422)
Manually annotated by BRENDA team
Fluegge, F.; Peters, T.
Complete assignment of Ala, Ile, Leu, Met and Val methyl groups of human blood group A and B glycosyltransferases using lanthanide-induced pseudocontact shifts and methyl-methyl NOESY
J. Biomol. NMR
70
245-259
2018
Homo sapiens (P16442)
Manually annotated by BRENDA team
Yamamoto, M.; Cid, E.; Yamamoto, F.
Crosstalk between ABO and Forssman (FORS) blood group systems FORS1 antigen synthesis by ABO gene-encoded glycosyltransferases
Sci. Rep.
7
41632
2017
Mus musculus (P38649)
Manually annotated by BRENDA team
Cid , E.; Yamamoto, M.; Yamamoto, F.
Amino acid substitutions at sugar-recognizing codons confer ABO blood group system-related alpha1,3 Gal(NAc) transferases with differential enzymatic activity
Sci. Rep.
9
846
2019
Homo sapiens (P16442)
Manually annotated by BRENDA team
Yamamoto, M.; Tarasco, M.C.; Cid, E.; Kobayashi, H.; Yamamoto, F.
ABO blood group A transferase and its codon 69 substitution enzymes synthesize FORS1 antigen of FORS blood group system
Sci. Rep.
9
9717
2019
Homo sapiens (P16442)
Manually annotated by BRENDA team