Information on EC 2.4.1.246 - mannosylfructose-phosphate synthase

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The expected taxonomic range for this enzyme is: Agrobacterium tumefaciens

EC NUMBER
COMMENTARY hide
2.4.1.246
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RECOMMENDED NAME
GeneOntology No.
mannosylfructose-phosphate synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GDP-mannose + D-fructose 6-phosphate = GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
mannosylfructose biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase
This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity. GDP-mannose can be replaced by ADP-mannose but with a concomitant decrease in activity. The product of this reaction is dephosphorylated by EC 3.1.3.79 (mannosylfructose-phosphate phosphatase) to form the non-reducing disaccharide mannosylfructose, which is the major endogenous osmolyte produced by several alpha-proteobacteria in response to osmotic stress. The F in the product name is used to indicate that the fructose residue of sucrose carries the substituent.
CAS REGISTRY NUMBER
COMMENTARY hide
92480-04-1
not distinguished from EC 2.4.1.167
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain C58
Uniprot
Manually annotated by BRENDA team
strain C58
Uniprot
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
GDP-mannose + D-fructose 6-phosphate
GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate
show the reaction diagram
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?
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