Reference on EC 2.4.1.198 - phosphatidylinositol N-acetylglucosaminyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Doering, T.L.; Masterson, W.J.; Englund, P.T.; Hart, G.W.
Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Origin of the non-acetylated glucosamine
J. Biol. Chem.
264
11168-11173
1989
Trypanosoma brucei
Milne, K.G.; Ferguson, M.A.J.; Masterson, W.J.
Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes
Eur. J. Biochem.
208
309-314
1992
Trypanosoma brucei
Hillmen, P.; Bessler, M.; Mason, P.J.; Watkins, W.M.; Luzzatto, L.
Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria
Proc. Natl. Acad. Sci. USA
90
5272-5276
1993
Homo sapiens
Takano, D.; Kishimoto, T.; Hayakawa, T.; Mitsui, T.; Hori, H.
Activity of phosphatidylinositol/UDP-GlcNAc:GlcNAc transferase in midgut tissue of Bombyx mori
Niigata Daigaku Nogakubu Kenkyu Hokoku
55
123-131
2003
Bombyx mori
-
Watanabe, R.; Inoue, N.; Westfall, B.; Taron, C.H.; Orlean, P.; Takeda, J.; Kinoshita, T.
The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1
EMBO J.
17
877-885
1998
Saccharomyces cerevisiae, Homo sapiens, Homo sapiens (Q9BRB3)
Hong, Y.; Oshihi, K.; Watanabe, R.; Endo, Y.; Maeda, Y.; Kinoshita, T.
GPI1 stabilizes an enzyme essential in the first step of glycosylphosphatidylinositol biosynthesis
J. Biol. Chem.
274
18582-18588
1999
Homo sapiens, Mus musculus (Q9QYT7), Mus musculus
Vidugiriene, J.; Sharma, D.K.; Smith, T.K.; Baumann, N.A.; Menon, A.K.
Segregation of glycosylphosphatidylinositol biosynthetic reactions in a subcompartment of the endoplasmic reticulum
J. Biol. Chem.
274
15202-15212
1999
Cricetulus griseus, Mus musculus
-
Watanabe, R.; Murakami, Y.; Marmor, M.; Inoue, N.; Maeda, Y.; Hino, J.; Kangawa, K.; Julius, M.; Kinoshita, T.
Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2
EMBO J.
19
4402-4411
2000
Homo sapiens, Homo sapiens (P57054), Homo sapiens (Q9BRB3), Mus musculus (Q9JHG1)
Kostova, Z.; Rancour, D.M.; Menon, A.K.; Orlean, P.
Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies Gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis
Biochem. J.
350
815-822
2000
Saccharomyces cerevisiae, Saccharomyces cerevisiae XM37-10c
-
Tiede, A.; Nischan, C.; Schubert, J.; Schmidt, R.
Characterization of the enzymatic complex for the first step in glycosylphosphatidylinositol biosynthesis
Int. J. Biochem. Cell Biol.
32
339-250
2000
Homo sapiens
Sobering, A.K.; Watanabe, R.; Romeo, M.J.; Yan, B.C.; Specht, C.A.; Orlean, P.; Riezman, H.; Levin, D.E.
Yeast Ras regulates the complex that catalyzes the first step in GPI-anchor biosynthesis at the ER
Cell
117
637-648
2004
Saccharomyces cerevisiae
Newman, H.A.; Romeo, M.J.; Lewis, S.E.; Yan, B.C.; Orlean, P.; Levin, D.E.
Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis
Eukaryot. Cell
4
1801-1807
2005
Saccharomyces cerevisiae
Murakami, Y.; Siripanyaphinyo, U.; Hong, Y.; Tashima, Y.; Maeda, Y.; Kinoshita, T.
The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component
Mol. Biol. Cell
16
5236-5246
2005
Homo sapiens (Q3MUY2), Homo sapiens
Li, H.; Zhou, H.; Luo, Y.; Ouyang, H.; Hu, H.; Jin, C.
Glycosylphosphatidylinositol (GPI) anchor is required in Aspergillus fumigatus for morphogenesis and virulence
Mol. Microbiol.
64
1014-1027
2007
Aspergillus fumigatus (Q6Q2B4), Aspergillus fumigatus, Aspergillus fumigatus YJ-407 (Q6Q2B4)
Oswal, N.; Sahni, N.S.; Bhattacharya, A.; Komath, S.S.; Muthuswami, R.
Unique motifs identify PIG-A proteins from glycosyltransferases of the GT4 family
BMC Evol. Biol.
8
168
2008
Actinobacillus succinogenes, Aeropyrum pernix, Alkaliphilus metalliredigens, Arabidopsis thaliana, Bacteroides thetaiotaomicron, Caenorhabditis elegans, Candida albicans, Clostridium beijerinckii, Clostridium tetani, Cryptosporidium parvum, Cutibacterium acnes, Desulfitobacterium hafniense, Dictyostelium discoideum, Drosophila melanogaster, Entamoeba histolytica, Giardia intestinalis, Halalkalibacterium halodurans, Homo sapiens, Leishmania major, Methanosarcina acetivorans, Methanosarcina barkeri, Methanothermobacter thermautotrophicus, Mycobacterium sp., Oryza sativa, Paramecium tetraurelia, Plasmodium falciparum, Pyrococcus furiosus, Rattus norvegicus, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Thermoplasma acidophilum, Trypanosoma brucei, [Mannheimia] succiniciproducens
Pilsyk, S.; Paszewski, A.
The Aspergillus nidulans pigP gene encodes a subunit of GPI-N-acetylglucosaminyltransferase which influences filamentation and protein secretion
Curr. Genet.
55
301-309
2009
Aspergillus nidulans (Q5AUG0), Aspergillus nidulans
Shao, M.; Liu, Z.Z.; Wang, C.D.; Li, H.Y.; Carron, C.; Zhang, H.W.; Shi, D.L.
Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos
Development
136
2121-2131
2009
Danio rerio, Xenopus laevis
Victoria, G.S.; Yadav, B.; Hauhnar, L.; Jain, P.; Bhatnagar, S.; Komath, S.S.
Mutual co-regulation between GPI-N-acetylglucosaminyltransferase and ergosterol biosynthesis in Candida albicans
Biochem. J.
443
619-625
2012
Candida albicans, Candida albicans BWP17
Murata, D.; Nomura, K.H.; Dejima, K.; Mizuguchi, S.; Kawasaki, N.; Matsuishi-Nakajima, Y.; Ito, S.; Gengyo-Ando, K.; Kage-Nakadai, E.; Mitani, S.; Nomura, K.
GPI-anchor synthesis is indispensable for the germline development of the nematode Caenorhabditis elegans
Mol. Biol. Cell
23
982-995
2012
Caenorhabditis elegans
Engel, J.; Schmalhorst, P.S.; Krueger, A.T.; Mueller, C.T.; Buettner, F.F.; Routier, F.H.
Characterization of an N-acetylglucosaminyltransferase involved in Aspergillus fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis
Glycobiology
25
1423-1430
2015
Aspergillus fumigatus
Yadav, A.; Singh, S.L.; Yadav, B.; Komath, S.S.
Saccharomyces cerevisiae Gpi2, an accessory subunit of the enzyme catalyzing the first step of glycosylphosphatidylinositol (GPI) anchor biosynthesis, selectively complements some of the functions of its homolog in Candida albicans
Glycoconj. J.
31
497-507
2014
Candida albicans (Q5A6L6), Candida albicans, Saccharomyces cerevisiae
Yadav, B.; Bhatnagar, S.; Ahmad, M.F.; Jain, P.; Pratyusha, V.A.; Kumar, P.; Komath, S.S.
First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling in Candida albicans
J. Biol. Chem.
289
3365-3382
2014
Candida albicans (Q5A6L6), Candida albicans
David, R.; Talbot, E.; Allen, B.; Wilson, A.; Arshad, U.; Doherty, A.
The development of an in vitro Pig-a assay in L5178Y cells
Arch. Toxicol.
92
1609-1623
2018
Mus musculus (Q64323), Mus musculus
Lee, C.C.; Ko, T.P.; Chen, C.T.; Chan, Y.T.; Lo, S.Y.; Chang, J.Y.; Chen, Y.W.; Chung, T.F.; Hsieh, H.J.; Hsiao, C.D.; Wang, A.H.
Crystal structure of PigA a prolyl thioester-oxidizing enzyme in prodigiosin biosynthesis
ChemBioChem
20
193-202
2019
Serratia marcescens (Q5W254)
Jain, P.; Sethi, S.C.; Pratyusha, V.A.; Garai, P.; Naqvi, N.; Singh, S.; Pawar, K.; Puri, N.; Komath, S.S.
Ras signaling activates glycosylphosphatidylinositol (GPI) anchor biosynthesis via the GPI-N-acetylglucosaminyltransferase (GPI-GnT) in Candida albicans
J. Biol. Chem.
293
12222-12238
2018
Candida albicans, Candida albicans (A0A1D8PHD4), Candida albicans (A0A1D8PKB8), Candida albicans (Q5A6L6), Candida albicans (Q5A9D6), Candida albicans ATCC MYA-2876, Candida albicans ATCC MYA-2876 (A0A1D8PHD4), Candida albicans ATCC MYA-2876 (A0A1D8PKB8), Candida albicans ATCC MYA-2876 (Q5A6L6), Candida albicans ATCC MYA-2876 (Q5A9D6)
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