Reference on EC 2.4.1.147 - acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schachter, H.; Brockhausen, I.; Hull, E.
High-performance liquid chromatography assays for N-acetylglucosaminyltransferases involved in N- and O-glycan synthesis
Methods Enzymol.
179
351-397
1989
Ovis aries, Homo sapiens, Platyrrhini, no activity in Canis familiaris, Rattus norvegicus, Sus scrofa
Brockhausen, I.; Rachaman, E.S.; Matta, K.L.; Schachter, H.
The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis
Carbohydr. Res.
120
3-16
1983
Rattus norvegicus
Brockhausen, I.; Matta, K.L.; Orr, J.; Schachter, H.
Mucin synthesis. UDP-GlcNAc:GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa
Biochemistry
24
1866-1874
1985
Homo sapiens, no activity in Canis familiaris, Ovis aries, Platyrrhini, Rattus norvegicus, Sus scrofa
Vavasseur, F.; Yang, J.M.; Dole, K.; Paulsen, H.; Brockhausen, I.
Synthesis of O-glycan core 3: characterization of UDP-GlcNAc:GalNAc-R beta3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines
Glycobiology
5
351-357
1995
Homo sapiens, Rattus norvegicus
Iwai, T.; Inaba, N.; Naundorf, A.; Zhang, Y.; Gotoh, M.; Iwasaki, H.; Kudo, T.; Togayachi, A.; Ishizuka, Y.; Nakanishi, H.; Narimatsu, H.
Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans
J. Biol. Chem.
277
12802-12809
2002
Homo sapiens (Q6ZMB0), Homo sapiens
Iwai, T.; Kudo, T.; Kawamoto, R.; Kubota, T.; Togayachi, A.; Hiruma, T.; Okada, T.; Kawamoto, T.; Morozumi, K.; Narimatsu, H.
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells
Proc. Natl. Acad. Sci. USA
102
4572-4577
2005
Homo sapiens
Westerlind, U.; Hagback, P.; Tidbaeck, B.; Wiik, L.; Blixt, O.; Razi, N.; Norberg, T.
Synthesis of deoxy and acylamino derivatives of lactose and use of these for probing the active site of Neisseria meningitidis N-acetylglucosaminyltransferase
Carbohydr. Res.
340
221-233
2005
Neisseria meningitidis
An, G.; Wei, B.; Xia, B.; McDaniel, J.M.; Ju, T.; Cummings, R.D.; Braun, J.; Xia, L.
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
J. Exp. Med.
204
1417-1429
2007
Mus musculus
Lee, S.; Hatakeyama, S.; Yu, S.; Bao, X.; Ohyama, C.; Khoo, K.; Fukuda, M.; Fukuda, M.
Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex
J. Biol. Chem.
284
17157-17169
2009
Homo sapiens
Wang, H.; Kim, J.J.; Denou, E.; Gallagher, A.; Thornton, D.J.; Shajib, M.S.; Xia, L.; Schertzer, J.D.; Grencis, R.K.; Philpott, D.J.; Khan, W.I.
New role of Nod proteins in regulation of intestinal goblet cell response in the context of innate host defense in an enteric parasite infection
Infect. Immun.
84
275-285
2015
Mus musculus (Q3USF0), Mus musculus C57BL/6 (Q3USF0)
Liu, J.; Jin, C.; Cherian, R.M.; Karlsson, N.G.; Holgersson, J.
O-glycan repertoires on a mucin-type reporter protein expressed in CHO cell pools transiently transfected with O-glycan core enzyme cDNAs
J. Biotechnol.
199
77-89
2015
Homo sapiens (Q6ZMB0)
Saito, F.; Sakamoto, I.; Kanatani, A.; Chiba, Y.
Manganese ion concentration affects production of human core 3 O-glycan in Saccharomyces cerevisiae
Biochim. Biophys. Acta
1860
1809-1820
2016
Homo sapiens (Q6ZMB0), Homo sapiens
Bergstrom, K.; Fu, J.; Johansson, M.E.; Liu, X.; Gao, N.; Wu, Q.; Song, J.; McDaniel, J.M.; McGee, S.; Chen, W.; Braun, J.; Hansson, G.C.; Xia, L.
Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice
Mucosal Immunol.
10
91-103
2017
Mus musculus (Q3USF0)
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