Information on EC 2.3.1.68 - glutamine N-acyltransferase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.3.1.68
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RECOMMENDED NAME
GeneOntology No.
glutamine N-acyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine
show the reaction diagram
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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-
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SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:L-glutamine N-acyltransferase
Phenylacetyl-CoA and (indol-3-yl)acetyl-CoA, but not benzoyl-CoA, can act as acyl donors. Not identical with EC 2.3.1.13 glycine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.
CAS REGISTRY NUMBER
COMMENTARY hide
9030-00-6
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
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Manually annotated by BRENDA team
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-
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
indoleacetyl-CoA + L-glutamine
CoA + indoleacetyl-L-glutamine
show the reaction diagram
phenylacetyl-CoA + L-glutamine
CoA + phenylacetyl-L-glutamine
show the reaction diagram
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
benzoyl-CoA
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weak competitive
butyryl-CoA
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0.4 mM, in presence of 100 mM L-glutamine, 50% loss of activity
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.035
phenylacetyl-CoA
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-
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.17
benzoyl-CoA
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with phenylacetyl-CoA as substrate
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE