Information on EC 2.3.1.63 - 1-alkylglycerophosphocholine O-acyltransferase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.3.1.63
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RECOMMENDED NAME
GeneOntology No.
1-alkylglycerophosphocholine O-acyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Ether lipid metabolism
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Metabolic pathways
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SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase
May be identical with EC 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase.
CAS REGISTRY NUMBER
COMMENTARY hide
58693-63-3
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
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Manually annotated by BRENDA team
no activity in Rattus norvegicus
liver microsomes
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-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine
CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
arachidonoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine
CoA + 2-arachidonoyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
linolenoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine
CoA + 2-linolenoyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
linoleoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine
CoA + 2-linoleoyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
no cation requirement
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
Ehrlich ascites tumor cells
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Manually annotated by BRENDA team