Reference on EC 2.3.1.47 - 8-amino-7-oxononanoate synthase
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Izumi, Y.; Kano, Y.; Inagaki, K.; Kawase, N.; Tani, Y.; Yamada, H.
Characterization of biotin biosynthetic enzymes of Bacillus sphaericus: a dethiobiotin producing bacterium
Agric. Biol. Chem.
45
1983-1989
1981
Lysinibacillus sphaericus, Lipomyces starkeyi, Sporobolomyces coprophilus, Sporidiobolus salmonicolor, Lysinibacillus sphaericus IFO 3525
-
Eidenberg, M.A.; Star, C.
Synthesis of 7-oxo-8-aminopelargonic acid, a biotin vitamer, in cell-free extracts of Escherichia coli biotin auxotrophs
J. Bacteriol.
96
1291-1297
1968
Escherichia coli
Ploux, O.; Marquet, A.
The 8-amino-7-oxopelargonate synthase from Bacillus sphaericus. Purification and preliminary characterization of the cloned enzyme overproduced in Escherichia coli
Biochem. J.
283
327-331
1992
Lysinibacillus sphaericus
Otsuka, A.J.; Buoncristiani, M.R.; Howard, P.K.; Flamm, J.; Johnson, C.; Yamamoto, R.; Uchida, K.; Cook, C.; Ruppert, J.; Matsuzaki, J.
The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon
J. Biol. Chem.
263
19577-19585
1988
Escherichia coli
Izumi, Y.; Sato, K.; Tani, Y.; Ogata, K.
Distribution of 7-keto-8-aminopelargonic acid synthetase in bacteria and the control mechanism of the enzyme activity
Agric. Biol. Chem.
37
1335-1340
1973
Klebsiella aerogenes, Enterobacter cloacae, Alcaligenes faecalis, Bacillus subtilis, Lysinibacillus sphaericus, Citrobacter freundii, Escherichia coli, Erwinia aroidea, Kocuria rosea, Pseudomonas fluorescens
-
Izumi, Y.; Morita, H.; Tani, Y.; Ogata, K.
Partial purification and some properties of a 7-keto-8-aminopelargonic acid synthetase, an enzyme involved in biotin biosynthesis
Agric. Biol. Chem.
37
1327-1333
1973
Lysinibacillus sphaericus
-
Ploux, O.; Marquet, A.
Mechanistic studies on the 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis
Eur. J. Biochem.
236
301-308
1996
Lysinibacillus sphaericus
Ploux, O.; Breyne, O.; Carillon, S.; Marquet, A.
Slow-binding and competitive inhibition of 8-amino-7-oxopelargonate synthase, a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis, by substrate and intermediate analogs: kinetic and binding studies
Eur. J. Biochem.
259
63-70
1999
Lysinibacillus sphaericus
Spinelli, S.; Ploux, O.; Marquet, A.; Anguille, C.; Jelsch, C.; Cambillau, C.; Martinez, C.
Crystallization and preliminary x-ray study of the 8-amino-7-oxopelargonate synthase from Bacillus sphaericus
Acta Crystallogr. Sect. D
52
866-868
1996
Lysinibacillus sphaericus
Webster, S.P.; Campopiano, D.J.; Alexeev, D.; Alexeeva, M.; Watt, R.M.; Sawyer, L.; Baxter, R.L.
Characterization of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl CoA condensing enzyme
Biochem. Soc. Trans.
26
S268
1998
Lysinibacillus sphaericus, Escherichia coli
Alexeev, D.; Alexeeva, M.; Baxter, R.L.; Campopiano, D.J.; Webster, S.P.; Sawyer, L.
The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme
J. Mol. Biol.
284
401-419
1998
Escherichia coli (P12998), Escherichia coli
Webster, S.P.; Alexeev, D.; Campopiano, D.J.; Watt, R.M.; Alexeeva, M.; Sawyer, L.; Baxter, R.L.
Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies
Biochemistry
39
516-528
2000
Escherichia coli
Kerbarh, O.; Campopiano, D.J.; Baxter, R.L.
Mechanism of alpha-oxoamine synthases: identification of the intermediate Claisen product in the 8-amino-7-oxononanoate synthase reaction
Chem. Commun. (Camb. )
2006
60-62
2006
Escherichia coli
Bhor, V.M.; Dev, S.; Vasanthakumar, G.R.; Kumar, P.; Sinha, S.; Surolia, A.
Broad substrate stereospecificity of the Mycobacterium tuberculosis 7-keto-8-aminopelargonic acid synthase: spectroscopic and kinetic studies
J. Biol. Chem.
281
25076-25088
2006
Mycobacterium tuberculosis
Alexeev, D.; Baxter, R.L.; Campopiano, D.J.; Kerbarh, O.; Sawyer, L.; Tomczyk, N.; Watt, R.; Webster, S.P.
Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine
Org. Biomol. Chem.
4
1209-1212
2006
Escherichia coli
Pinon, V.; Ravanel, S.; Douce, R.; Alban, C.
Biotin synthesis in plants. The first committed step of the pathway is catalyzed by a cytosolic 7-keto-8-aminopelargonic acid synthase
Plant Physiol.
139
1666-1676
2005
Arabidopsis thaliana (Q8GW43)
Mann, S.; Colliandre, L.; Labesse, G.; Ploux, O.
Inhibition of 7,8-diaminopelargonic acid aminotransferase from Mycobacterium tuberculosis by chiral and achiral anologs of its substrate: biological implications
Biochimie
91
826-834
2009
Escherichia coli, Mycobacterium tuberculosis, Escherichia coli C268
Turbeville, T.D.; Zhang, J.; Adams, W.C.; Hunter, G.A.; Ferreira, G.C.
Functional asymmetry for the active sites of linked 5-aminolevulinate synthase and 8-amino-7-oxononanoate synthase
Arch. Biochem. Biophys.
511
107-117
2011
Escherichia coli (P12998)
Kubota, T.; Izumi, Y.
Detection and characterization of a thermophilic biotin biosynthetic enzyme, 7-keto-8-aminopelargonic acid synthase, from various thermophiles
Biosci. Biotechnol. Biochem.
76
685-690
2012
Aquifex aeolicus, Acetivibrio thermocellus, Escherichia coli, Symbiobacterium thermophilum, Thermosynechococcus vestitus, Geobacillus kaustophilus, Geobacillus kaustophilus JCM 12893, Symbiobacterium thermophilum IAM14863, Acetivibrio thermocellus ATCC 27405
Cho, J.; Kang, S.; Choi, J.; Ko, Y.; Hwang, I.; Kang, N.
The identification of binding mode for Arabidopsis thaliana 7-keto-8-aminopelargonic acid synthase (AtKAPAS) inhibitors
Bull. Korean Chem. Soc.
33
1597-1602
2012
Arabidopsis thaliana
-
Hwang, I.; Choi, J.; Song, H.; Cho, S.; Lim, H.; Park, N.; Lee, D.
Validation of 7-keto-8-aminopelargonic acid synthase as a potential herbicide target with lead compound triphenyltin acetate
Pestic. Biochem. Physiol.
97
24-31
2010
Arabidopsis thaliana
-
Fan, S.; Li, D.; Fleming, J.; Hong, Y.; Chen, T.; Zhou, L.; Bi, L.; Wang, D.; Zhang, X.; Chen, G.
Purification and X-ray crystallographic analysis of 7-keto-8-aminopelargonic acid (KAPA) synthase from Mycobacterium smegmatis
Acta Crystallogr. Sect. F
70
1372-1375
2014
Mycolicibacterium smegmatis (A0QX65), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084 (A0QX65)
Fan, S.; Li, D.F.; Wang, D.C.; Fleming, J.; Zhang, H.; Zhou, Y.; Zhou, L.; Zhou, J.; Chen, T.; Chen, G.; Zhang, X.E.; Bi, L.
Structure and function of Mycobacterium smegmatis 7-keto-8-aminopelargonic acid (KAPA) synthase
Int. J. Biochem. Cell Biol.
58
71-80
2015
Mycolicibacterium smegmatis (A0QX65), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084 (A0QX65)
Hahn, H.G.; Choi, J.S.; Lim, H.K.; Lee, K.I.; Hwang, I.T.
Triazolyl phenyl disulfides: 8-amino-7-oxononanoate synthase inhibitors as potential herbicides
Pestic. Biochem. Physiol.
125
78-83
2015
Arabidopsis thaliana (Q8GW43), Arabidopsis thaliana
Lin, L.; Jiang, N.; Wu, H.; Mei, Y.; Yang, J.; Tan, R.
Cytotoxic and antibacterial polyketide-indole hybrids synthesized from indole-3-carbinol by Daldinia eschscholzii
Acta Pharm. Sin. B
9
369-380
2019
Daldinia eschscholtzii
Manandhar, M.; Cronan, J.E.
A Canonical biotin synthesis enzyme, 8-amino-7-oxononanoate synthase (BioF), utilizes different acyl chain donors in Bacillus subtilis and Escherichia coli
Appl. Environ. Microbiol.
84
e02084-17
2018
Bacillus subtilis (P53556), Bacillus subtilis, Bacillus subtilis 168 (P53556), Escherichia coli (P12998), Escherichia coli
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