Reference on EC 2.3.1.28 - chloramphenicol O-acetyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Shaw, W.V.
The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli
J. Biol. Chem.
242
687-693
1967
Escherichia coli
Shaw, W.V.; Brodsky, R.F.
Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus
J. Bacteriol.
95
28-36
1968
Escherichia coli, Staphylococcus aureus, Staphylococcus aureus C22.1
Shaw, W.V.
Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria
Methods Enzymol.
43
737-755
1975
Agrobacterium tumefaciens, Streptococcus pneumoniae, Escherichia coli, Enterococcus faecalis, Staphylococcus sp.
Cardoso, M.; Schwarz, S.
Characterization of the chloramphenicol acetyltransferase variants encoded by the plasmids pSCS6 and pSCS7 from Staphylococcus aureus
J. Gen. Microbiol.
138
275-281
1992
Staphylococcus aureus
Roberts, M.; Corney, A.; Shaw, W.V.
Molecular characterization of three chloramphenicol acetyltransferases isolated from Haemophilus influenzae
J. Bacteriol.
151
737-741
1982
Haemophilus influenzae
Thibault, G.; Guitard, M.; Daigneault, R.
A study of the enzymatic inactivation of chloramphenicol by highly purified chloramphenicol acetyltransferase
Biochim. Biophys. Acta
614
339-349
1980
Escherichia coli
Masuyoshi, S.; Okubo, T.; Inoue, M.; Mitsuhashi, S.
Purification and some properties of a chloramphenicol acetyltransferase mediated by plasmids from Vibrio anguillarum
J. Biochem.
104
131-135
1988
Vibrio anguillarum
Murray, I.A.; Martinez-Suarez, J.V.; Close, T.J.; Shaw, W.V.
Nucleotide sequences of genes encoding the type II chloramphenicol acetyltransferases of Escherichia coli and Haemophilus influenzae, which are sensitive to inhibition by thiol-reactive reagents
Biochem. J.
272
505-510
1990
Escherichia coli, Haemophilus influenzae
Ellis, J.; Bagshaw, C.R.; Shaw, W.V.
Substrate binding to chloramphenicol acetyltransferase: evidence for negative cooperativity from equilibrium and kinetic constants for binary and ternary complexes
Biochemistry
30
10806-10813
1991
Escherichia coli
Zaidenzaig, Y.; Fitton, J.E.; Packman, L.C.; Shaw, W.V.
Characterization and comparison of chloramphenicol acetyltransferase variants
Eur. J. Biochem.
100
609-618
1979
Agrobacterium tumefaciens, Clostridium perfringens, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Proteus mirabilis, Staphylococcus sp., Streptococcus agalactiae, Streptomyces acrimycini
Nolte, G.; Sussmuth, R.
Purification and characterization of chloramphenicol acetyltransferase from Flavobacterium CB60
J. Gen. Microbiol.
133
2115-2122
1987
Flavobacterium sp., Flavobacterium sp. CB60
Tanaka, H.; Izaki, K.; Takahashi, H.
Some properties of chloramphenicol acetyltransferase, with particular reference to the mechanism of inhibition by basic triphenylmethane dyes
J. Biochem.
76
1009-1019
1974
Escherichia coli
Fitton, J.E.; Shaw, W.V.
Comparison of chloramphenicol acetyltransferase variants in staphylococci. Purification, inhibitor studies and N-terminal sequences
Biochem. J.
177
575-582
1979
Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus sp.
Guitard, M.; Daigneault, R.
Purification of Escherichia coli chloramphenicol acetyltransferase by affinity chromatography
Can. J. Biochem.
52
1087-1090
1974
Escherichia coli, Escherichia coli W677/HJR66
Kleanthous, C.; Shaw, W.V.
Analysis of the mechanism of chloramphenicol acetyltransferase by steady-state kinetics. Evidence for a ternary-complex mechanism
Biochem. J.
223
211-220
1984
Escherichia coli, Escherichia coli J53(R387)
Tian, Y.; Beaman, T.W.; Roderick, S.L.
Purification and crystallization of Pseudomonas aeruginosa chloramphenicol acetyltransferase
Proteins
28
298-300
1997
Pseudomonas aeruginosa
Chirakkal, H.; Ford, G.C.; Moir, A.
Analysis of a conserved hydrophobic pocket important for the thermostability of Bacillus pumilus chloramphenicol acetyltransferase (CAT-86)
Protein Eng.
14
161-166
2001
Bacillus pumilus
Chen, M.W.; Nagarajan, V.
Chloramphenicol acetyltransferase, a cytoplasmic protein is incompatible for export from Bacillus subtilis
J. Bacteriol.
175
5697-5700
1993
Bacillus subtilis
Van der Schueren, J.; Robben, J.; Volckaert, G.
Misfolding of chloramphenicol acetyltransferase due to carboxy-terminal truncation can be corrected by second-site mutations
Protein Eng.
11
1211-1217
1998
Escherichia coli
Kim, S.J.; Jeon, H.Y.; Kim, H.B.
Chloramphenicol acetyltransferase expression of Escherichia coli is increased at 42 DegC
Biotechnol. Tech.
11
435-438
1997
Escherichia coli
-
Kamrud, K.I.; Olson, K.E.; Higgs, S.; Powers, A.M.; Carlson, J.O.; Beaty, B.J.
Detection of expressed chloramphenicol acetyltransferase in the saliva of Culex pipiens mosquitoes
Insect Biochem. Mol. Biol.
27
423-429
1997
Culex pipiens
Zhou, M.; Lu, M.L.; Qiu, W.; Campbell, R.L.; Nahoum, V.; Lapointe, J.; Roy, P.H.; Lin, S.X.
Crystallization and preliminary X-ray diffraction analysis of the chloramphenicol acetyltransferase from Tn2424
Acta Crystallogr. Sect. D
57
281-283
2001
Escherichia coli
El-Gamal, B.; Temsah, S.; Olama, Z.; Mohamed, A.; El-Sayed, M.
Purification and characterization of chloramphenicol acetyltransferase from Morganella morganii
J. Biochem. Mol. Biol.
34
415-420
2001
Morganella morganii
-
White, P.A.; Stokes, H.W.; Bunny, K.L.; Hall, R.M.
Characterization of a chloramphenicol acetyltransferase determinant found in the chromosome of Pseudomonas aeruginosa
FEMS Microbiol. Lett.
175
27-35
1999
Pseudomonas aeruginosa
Day, P.J.; Murray, I.A.; Shaw, W.V.
Properties of hybrid active sites in oligomeric proteins: kinetic and ligand binding studies with chloramphenicol acetyltransferase trimers
Biochemistry
34
6416-6422
1995
Escherichia coli
Van der Schueren, J.; Robben, J.; Goossens, K.; Heremans, K.; Volckaert, G.
Identification of local carboxy-terminal hydrophobic interactions essential for folding or stability of chloramphenicol acetyltransferase
J. Mol. Biol.
256
878-888
1996
Escherichia coli
Alipour, H.; Eriksson, P.; Norbeck, J.; Blomberg, A.
Quantitative aspects of the use of bacterial chloramphenicol acetyltransferase as a reporter system in the yeast Saccharomyces cerevisiae
Anal. Biochem.
270
153-158
1999
Escherichia coli
El-Gamal, B.A.; Olama, Z.A.; Mohamed, A.E.; El-Sayed, M.M.
Purification and characterization of chloramphenicol acetyltransferase from Morganella morganii
Egypt. J. Biochem. Mol. Biol.
21
215-229
2003
Morganella morganii
-
Wang, J.; Liu, J.H.
Mutations in the chloramphenicol acetyltransferase (S61G, Y105C) increase accumulated amounts and resistance in Pseudomonas aeruginosa
FEMS Microbiol. Lett.
236
197-204
2004
Pseudomonas aeruginosa, Pseudomonas aeruginosa Pahcr
Sohaskey, C.D.
Enzymatic inactivation and reactivation of chloramphenicol by Mycobacterium tuberculosis and Mycobacterium bovis
FEMS Microbiol. Lett.
240
187-192
2004
Mycobacterium tuberculosis, Mycobacterium tuberculosis variant bovis
Qiu, W.; Shi, R.; Lu, M.L.; Zhou, M.; Roy, P.H.; Lapointe, J.; Lin, S.X.
Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424
Proteins
57
858-861
2004
Escherichia coli
Beaman, T.W.; Sugantino, M.; Roderick, S.L.
Structure of the hexapeptide xenobiotic acetyltransferase from Pseudomonas aeruginosa
Biochemistry
37
6689-6696
1998
Pseudomonas aeruginosa, Pseudomonas aeruginosa PA 103
Christensen, T.; Trabbic-Carlson, K.; Liu, W.; Chilkoti, A.
Purification of recombinant proteins from Escherichia coli at low expression levels by inverse transition cycling
Anal. Biochem.
360
166-168
2007
Escherichia coli
Panchenko, T.; Zhu, W.W.; Montclare, J.K.
Influence of global fluorination on chloramphenicol acetyltransferase activity and stability
Biotechnol. Bioeng.
94
921-930
2006
Escherichia coli
Voloshchuk, N.; Lee, M.X.; Zhu, W.W.; Tanrikulu, I.C.; Montclare, J.K.
Fluorinated chloramphenicol acetyltransferase thermostability and activity profile: Improved thermostability by a single-isoleucine mutant
Bioorg. Med. Chem. Lett.
17
5907-5911
2007
Escherichia coli
Galopin, S.; Cattoir, V.; Leclercq, R.
A chromosomal chloramphenicol acetyltransferase determinant from a probiotic strain of Bacillus clausii
FEMS Microbiol. Lett.
296
185-189
2009
Alkalihalobacillus clausii (Q6XD71), Alkalihalobacillus clausii
Eom, H.J.; Park, J.M.; Seo, M.J.; Kim, M.D.; Han, N.S.
2 Monitoring of Leuconostoc mesenteroides DRC starter in fermented vegetable by random integration of chloramphenicol acetyltransferase gene
J. Ind. Microbiol. Biotechnol.
35
953-959
2008
Escherichia coli, Staphylococcus sp.
Van Dorst, B.; Mehta, J.; Rouah-Martin, E.; Backeljau, J.; De Coen, W.; Eeckhout, D.; De Jaeger, G.; Blust, R.; Robbens, J.
Selection of scFv phages specific for chloramphenicol acetyl transferase (CAT), as alternatives for antibodies in CAT detection assays
J. Appl. Toxicol.
32
783-789
2012
Escherichia coli
Li, W.; Ruf, S.; Bock, R.
Chloramphenicol acetyltransferase as selectable marker for plastid transformation
Plant Mol. Biol.
76
443-451
2011
Nicotiana tabacum
Biswas, T.; Houghton, J.L.; Garneau-Tsodikova, S.; Tsodikov, O.V.
The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI
Protein Sci.
21
520-530
2012
Escherichia coli (P62577)
Kobayashi, J.; Furukawa, M.; Ohshiro, T.; Suzuki, H.
Thermoadaptation-directed evolution of chloramphenicol acetyltransferase in an error-prone thermophile using improved procedures
Appl. Microbiol. Biotechnol.
99
5563-5572
2015
Staphylococcus aureus
Choi, I.; Kim, D.E.; Ahn, J.H.; Yeo, W.S.
On-chip enzymatic assay for chloramphenicol acetyltransferase using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Colloids Surf. B Biointerfaces
136
465-469
2015
Escherichia coli
Appu, A.P.; Arun, P.; Krishnan, J.K.; Moffett, J.R.; Namboodiri, A.M.
Rapid intranasal delivery of chloramphenicol acetyltransferase in the active form to different brain regions as a model for enzyme therapy in the CNS
J. Neurosci. Methods
259
129-134
2016
Escherichia coli
Brewitz, H.H.; Goradia, N.; Schubert, E.; Galler, K.; Kuehl, T.; Syllwasschy, B.; Popp, J.; Neugebauer, U.; Hagelueken, G.; Schiemann, O.; Ohlenschlaeger, O.; Imhof, D.
Heme interacts with histidine- and tyrosine-based protein motifs and inhibits enzymatic activity of chloramphenicol acetyltransferase from Escherichia coli
Biochim. Biophys. Acta
1860
1343-1353
2016
Escherichia coli (P62577), Escherichia coli
Seo, H.; Lee, J.W.; Garcia, S.; Trinh, C.T.
Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium thermocellum at elevated temperatures
Biotechnol. Biofuels
12
245
2019
Staphylococcus aureus
Zhang, G.; Sun, K.; Ai, G.; Li, J.; Tang, N.; Song, Y.; Wang, C.; Feng, J.
A novel family of intrinsic chloramphenicol acetyltransferase CATC in Vibrio parahaemolyticus Naturally occurring variants reveal diverse resistance levels against chloramphenicol
Int. J. Antimicrob. Agents
54
75-79
2019
Vibrio sp.
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