Disease on EC 2.3.1.250 - [Wnt protein] O-palmitoleoyl transferase
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Adenocarcinoma
Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models.
Adenocarcinoma of Lung
Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models.
Adenomatous Polyposis Coli
RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
Adenomatous Polyposis Coli
Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.
Airway Obstruction
Unusual causes of fatal upper aerodigestive tract obstruction in wild bottlenose dolphins (Tursiops aduncus).
Alopecia
Regional alopecia and dermatitis due to Lodderomyces elongisporus in a North American porcupine (Erethizon dorsatum).
Anophthalmos
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Arthritis, Infectious
Ultrasonographic diagnosis of septic arthritis secondary to porcupine quill migration in a dog.
Ataxia
Behavior, movements, and demographics of rabid raccoons in Ontario, Canada: management implications.
Ataxia
Cervical porcupine quill foreign body involving the spinal cord of a dog: A description of various imaging modality findings.
Bone Resorption
Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.
Breast Neoplasms
Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.
Breast Neoplasms
Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion.
Bronchiectasis
From hemp seed and porcupine quill to HRCT: advances in the diagnosis and epidemiology of bronchiectasis.
Bronchopneumonia
Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia.
Carcinogenesis
Diminished WNT -> ?-catenin -> c-MYC signaling is a barrier for malignant progression of BRAFV600E-induced lung tumors.
Carcinogenesis
PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.
Carcinogenesis
Responses of Porcupine and Wntless proteins to oxidative, hypoxic and endoplasmic reticulum stresses.
Carcinoma
Inhibition of CBP/?-catenin and porcupine attenuates Wnt signaling and induces apoptosis in head and neck carcinoma cells.
Carcinoma
Misexpression of mouse porcupine isoforms modulates the differentiation of P19 embryonic carcinoma cells.
Carcinoma
Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.
Carcinoma
Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
Carcinoma, Hepatocellular
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Carcinoma, Non-Small-Cell Lung
Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.
Carcinoma, Renal Cell
Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
Cardiomegaly
A novel porcupine inhibitor blocks WNT pathways and attenuates cardiac hypertrophy.
Cardiomegaly
Wnt-C59 Attenuates Pressure Overload-Induced Cardiac Hypertrophy via Interruption of Wnt Pathway.
Cataract
Intrauterine fetal death with subsequent quill exfoliation and dissemination in a North American porcupine (Erethizon dorsatum).
Chagas Disease
Wnt Signaling Plays a Key Role in the Regulation of the Immune Response and Cardiac Damage during Trypanosoma cruzi Infection.
Chondrodysplasia Punctata
PORCN mutations in focal dermal hypoplasia: coping with lethality.
Coloboma
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Colonic Neoplasms
Responses of Porcupine and Wntless proteins to oxidative, hypoxic and endoplasmic reticulum stresses.
Colorectal Neoplasms
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Colorectal Neoplasms
RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
Congenital Abnormalities
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Cysts
Focal dermal hypoplasia (Goltz-Gorlin syndrome): a new case with a novel variant in the PORCN gene (c.1250T>C:p.F417S) and unusual spinal anomaly.
Cysts
Imaging diagnosis--Vertebral canal porcupine quill with presumptive secondary arachnoid diverticulum.
Cysts
Latest Quaternary palaeoceanographic change in the eastern North Atlantic based upon a dinoflagellate cyst event ecostratigraphy.
Dengue
Antioxidant and Intracellular Reactive Oxygen Species/Reactive Nitrogen Species Scavenging Activities of Three Porcupine Bezoars from
Dermatitis
Regional alopecia and dermatitis due to Lodderomyces elongisporus in a North American porcupine (Erethizon dorsatum).
Distemper
Porcupine quills in raccoons as an indicator of rabies, distemper, or both diseases: disease management implications.
Diverticulum
Imaging diagnosis--Vertebral canal porcupine quill with presumptive secondary arachnoid diverticulum.
Dyspnea
Fatal Aspergillus flavus rhinitis with gastrointestinal gaseous distension in a Cape porcupine.
Encephalitis
Baylisascaris procyonis encephalitis in Patagonian conures (Cyanoliseus patagonus), crested screamers (Chauna torquata), and a western Canadian porcupine (Erethizon dorsatum epixanthus) in a Manitoba zoo.
Encephalomyelitis
Fatal Systemic Toxoplasma gondii Infection in a Red Squirrel (Sciurus vulgaris), a Swinhoe's Striped Squirrel (Tamiops swinhoei) and a New World Porcupine (Erethizontidae sp.).
Endocarditis
Fungal pericarditis and endocarditis secondary to porcupine quill migration in a dog.
Endometrial Neoplasms
Chemoresistance and targeting of growth factors/cytokines signalling pathways: towards the development of effective therapeutic strategy for endometrial cancer.
Eye Abnormalities
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Fetal Death
Intrauterine fetal death with subsequent quill exfoliation and dissemination in a North American porcupine (Erethizon dorsatum).
Fibrosarcoma
Precise Regulation of Porcupine Activity is Required for Physiological Wnt Signaling.
Fibrosarcoma
Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion.
Focal Dermal Hypoplasia
A non-mosaic PORCN mutation in a male with severe congenital anomalies overlapping focal dermal hypoplasia.
Focal Dermal Hypoplasia
A nonsense porcn mutation in severe focal dermal hypoplasia with natal teeth.
Focal Dermal Hypoplasia
A novel mutation in the PORCN gene underlying a case of almost unilateral focal dermal hypoplasia.
Focal Dermal Hypoplasia
A Novel PORCN Frameshift Mutation Leading to Focal Dermal Hypoplasia: A Case Report.
Focal Dermal Hypoplasia
A novel PORCN mutation in a severe case of Focal Dermal Hypoplasia.
Focal Dermal Hypoplasia
A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells.
Focal Dermal Hypoplasia
Blaschko Linear Enamel Defects - A Marker for Focal Dermal Hypoplasia: Case Report of Focal Dermal Hypoplasia.
Focal Dermal Hypoplasia
Co-occurrence of severe Goltz-Gorlin syndrome and pentalogy of Cantrell - Case report and review of the literature.
Focal Dermal Hypoplasia
Cognitive and psychological functioning in focal dermal hypoplasia.
Focal Dermal Hypoplasia
De Novo PORCN and ZIC2 Mutations in a Highly Consanguineous Family.
Focal Dermal Hypoplasia
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia.
Focal Dermal Hypoplasia
Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome.
Focal Dermal Hypoplasia
Deletion of porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (goltz syndrome).
Focal Dermal Hypoplasia
DETECTING PORCN MICRODELETIONS IN A LARGE FAMILY WITH FOCAL DERMAL HYPOPLASIA.
Focal Dermal Hypoplasia
Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins.
Focal Dermal Hypoplasia
Expanding the phenotypic spectrum of PORCN variants in two males with syndromic microphthalmia.
Focal Dermal Hypoplasia
Focal dermal hypoplasia (Goltz-Gorlin syndrome): a new case with a novel variant in the PORCN gene (c.1250T>C:p.F417S) and unusual spinal anomaly.
Focal Dermal Hypoplasia
Focal Dermal Hypoplasia Due to De Novo Mutation c.1061T>C(p.Leu354Pro) in the PORCN Gene: Importance of Early Diagnosis and Multidisciplinary Follow-Up.
Focal Dermal Hypoplasia
Focal dermal hypoplasia in a male patient due to mosaicism for a novel PORCN single nucleotide deletion.
Focal Dermal Hypoplasia
Focal dermal hypoplasia resulting from a new nonsense mutation, p.E300X, in the PORCN gene.
Focal Dermal Hypoplasia
Focal Dermal Hypoplasia with a De novo Mutation p.E300* of PORCN Gene in a Male Infant.
Focal Dermal Hypoplasia
Goltz syndrome in males: A clinical report of a male patient carrying a novel PORCN variant and a review of the literature.
Focal Dermal Hypoplasia
Growth, nutritional, and gastrointestinal aspects of focal dermal hypoplasia (Goltz-Gorlin syndrome).
Focal Dermal Hypoplasia
Identification of key residues and regions important for porcupine-mediated Wnt acylation.
Focal Dermal Hypoplasia
Implementation of high-resolution melting analysis of the porcupine (PORCN) gene for molecular diagnosis of focal dermal hypoplasia: Identification of a novel mutation.
Focal Dermal Hypoplasia
Mosaic focal dermal hypoplasia caused by a novel somatic mutation in PORCN detected in affected skin.
Focal Dermal Hypoplasia
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Focal Dermal Hypoplasia
Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia.
Focal Dermal Hypoplasia
Non-syndromic anophthalmia/microphthalmia can be caused by a PORCN variant inherited in X-linked recessive manner.
Focal Dermal Hypoplasia
Novel and recurrent PORCN gene mutations in almost unilateral and typical focal dermal hypoplasia patients.
Focal Dermal Hypoplasia
Pharyngeal Presentation of Goltz Syndrome: A Case Report with Review of the Literature.
Focal Dermal Hypoplasia
PORCN gene mutations and the protean nature of focal dermal hypoplasia.
Focal Dermal Hypoplasia
PORCN mutations and variants identified in patients with focal dermal hypoplasia through diagnostic gene sequencing.
Focal Dermal Hypoplasia
Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos.
Focal Dermal Hypoplasia
Precise Regulation of Porcupine Activity is Required for Physiological Wnt Signaling.
Focal Dermal Hypoplasia
Survival of a Male Mosaic for PORCN Mutation with Mild Focal Dermal Hypoplasia Phenotype.
Focal Dermal Hypoplasia
Syringocystadenoma papilliferum in a patient with focal dermal hypoplasia due to a novel PORCN mutation.
Focal Dermal Hypoplasia
Three novel mutations in the PORCN gene underlying focal dermal hypoplasia.
Focal Dermal Hypoplasia
Two female cases of focal dermal hypoplasia: One new case with a novel variant in PORCN (c.808_811delGGGG).
Focal Dermal Hypoplasia
Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia.
Focal Dermal Hypoplasia
[A novel PORCN gene mutation in a patient with focal dermal hypoplasia].
Genetic Diseases, Inborn
Growth, nutritional, and gastrointestinal aspects of focal dermal hypoplasia (Goltz-Gorlin syndrome).
Genetic Diseases, Inborn
The PORCN non-Goltz spectrum (PONGOS): A new group of genetic disorders.
Giardiasis
First report of Giardia duodenalis infection in the crested porcupine (Hystrix cristata L., 1758).
Glioblastoma
Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.
Glioblastoma
Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.
Glioma
Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro.
Head and Neck Neoplasms
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Hemangioma
An Xp11.23 deletion containing PORCN may also cause angioma serpiginosum, a cosmetic skin disease associated with extreme skewing of X-inactivation.
Ichthyosis
Story of the original porcupine men; classic descriptions of ichthyosis hystrix.
Infections
Cutaneous infection of a porcupine (Erethizon dorsatum) by Aureobasidium pullulans.
Infections
Echinococcus ortleppi, the cattle strain in a crested porcupine (Hystrix cristata): A new host record.
Infections
Encephalomyocarditis virus infection in Macaca sylvanus and Hystrix cristata from an Italian rescue centre for wild and exotic animals.
Infections
Fatal Systemic Toxoplasma gondii Infection in a Red Squirrel (Sciurus vulgaris), a Swinhoe's Striped Squirrel (Tamiops swinhoei) and a New World Porcupine (Erethizontidae sp.).
Infections
First report of Giardia duodenalis infection in the crested porcupine (Hystrix cristata L., 1758).
Infections
Infection of the porcupine (Histrix indica) with Trichostrongylus orientalis in the Caspian Sea Area, Iran.
Infections
Infrequency of gross skin lesions among Panamanian forest mammals with cutaneous leishmaniasis.
Infections
Regional alopecia and dermatitis due to Lodderomyces elongisporus in a North American porcupine (Erethizon dorsatum).
Infections
Trypanosomatid infections in captive wild mammals and potential vectors at the Brasilia Zoo, Federal District, Brazil.
Infections
Wnt Signaling Plays a Key Role in the Regulation of the Immune Response and Cardiac Damage during Trypanosoma cruzi Infection.
Infections
[Studies on reservoirs and wild vectors of trypanosomiasis cruzi. XVI. Natural infection of a porcupine, Coendou insidiosus insidiosus (Kuhl, 1820) by a cruzi-like trypanosoma]
Intervertebral Disc Displacement
Cervical intervertebral disk protrusion, diskospondylitis, and porcupine quill foreign body in a dog.
Kidney Neoplasms
Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma.
Larva Migrans
Cerebral Larva Migrans Caused by Baylisascaris spp. in a Free-ranging North American Porcupine ( Erethizon dorsatum ).
Leishmaniasis, Visceral
Leishmania (Leishmania) hertigi in a porcupine (Coendou sp.) found in Brasília, Federal District, Brazil.
Lethargy
Fatal Aspergillus flavus rhinitis with gastrointestinal gaseous distension in a Cape porcupine.
Lung Neoplasms
Porcupine inhibitor LGK?974 inhibits Wnt/??catenin signaling and modifies tumor?associated macrophages resulting in inhibition of the malignant behaviors of non?small cell lung cancer cells.
Lymphadenitis
Fatal Systemic Toxoplasma gondii Infection in a Red Squirrel (Sciurus vulgaris), a Swinhoe's Striped Squirrel (Tamiops swinhoei) and a New World Porcupine (Erethizontidae sp.).
Lymphoma
A new candidate site for a tumor suppressor gene involved in mouse thymic lymphomagenesis is located on the distal part of chromosome 4.
Lymphoma
Malignant immunoblastic lymphoma with filopodia (so-called anemone or porcupine cell tumour).
Lymphoma
Spicule or porcupine sign of primary gastric lymphoma: a correlative study of radiological finding with histology.
Lymphoma, Non-Hodgkin
[Lymphosarcoma (leucosis) in a porcupine (Histrix galeate) (brief clinical report)]
Lymphoma, T-Cell
Disseminated T-cell lymphoma in a Brazilian porcupine (Coendou prehensilis).
Malaria
The phylogeny of rodent malaria parasites: simultaneous analysis across three genomes.
Malaria
The primary structure of the circumsporozoite protein of Plasmodium atheruri, a malaria parasite of the African porcupine Atherurus africanus.
Melanoma
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.
Melanoma
Metastatic malignant melanoma in a prehensile-tailed porcupine (Coendou prehensilis).
Microphthalmos
Expanding the phenotypic spectrum of PORCN variants in two males with syndromic microphthalmia.
Microphthalmos
Focal dermal hypoplasia (Goltz-Gorlin syndrome): a new case with a novel variant in the PORCN gene (c.1250T>C:p.F417S) and unusual spinal anomaly.
Microphthalmos
Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.
Mycoses
DIAGNOSIS AND SUCCESSFUL TREATMENT OF A POTENTIALLY ZOONOTIC DERMATOPHYTOSIS CAUSED BY MICROSPORUM GYPSEUM IN A ZOO-HOUSED NORTH AMERICAN PORCUPINE (ERETHIZON DORSATUM).
Myocarditis
Fatal Systemic Toxoplasma gondii Infection in a Red Squirrel (Sciurus vulgaris), a Swinhoe's Striped Squirrel (Tamiops swinhoei) and a New World Porcupine (Erethizontidae sp.).
Neoplasm Metastasis
Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma.
Neoplasms
A new candidate site for a tumor suppressor gene involved in mouse thymic lymphomagenesis is located on the distal part of chromosome 4.
Neoplasms
An in vitro fatty acylation assay reveals a mechanism for Wnt recognition by the acyltransferase Porcupine.
Neoplasms
Antioxidant and Intracellular Reactive Oxygen Species/Reactive Nitrogen Species Scavenging Activities of Three Porcupine Bezoars from
Neoplasms
Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review).
Neoplasms
Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins.
Neoplasms
Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis.
Neoplasms
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.
Neoplasms
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse.
Neoplasms
In vitro reconstitution of Wnt acylation reveals structural determinants of substrate recognition by the acyltransferase human Porcupine.
Neoplasms
Inhibiting WNT Ligand Production for Improved Immune Recognition in the Ovarian Tumor Microenvironment.
Neoplasms
Malignant immunoblastic lymphoma with filopodia (so-called anemone or porcupine cell tumour).
Neoplasms
Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer.
Neoplasms
Peritoneal inflammatory myofibroblastic tumor in a brush-tailed porcupine (Atherurus macrourus).
Neoplasms
Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.
Neoplasms
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.
Neoplasms
PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.
Neoplasms
Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.
Neoplasms
Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.
Neoplasms
Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice.
Neoplasms
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Neoplasms
Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes.
Neoplasms
Promoter Hypomethylation and Increased Expression of the Long Non-coding RNA LINC00152 Support Colorectal Carcinogenesis.
Neoplasms
Responses of Porcupine and Wntless proteins to oxidative, hypoxic and endoplasmic reticulum stresses.
Neoplasms
RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
Neoplasms
The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
Neoplasms
Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment.
Neurodegenerative Diseases
Modulating Wnt signaling at the root: Porcupine and Wnt acylation.
Neuroendocrine Tumors
Inhibition of Wnt/?-Catenin Signaling in Neuroendocrine Tumors in vitro: Antitumoral Effects.
Neurologic Manifestations
Cerebral Larva Migrans Caused by Baylisascaris spp. in a Free-ranging North American Porcupine ( Erethizon dorsatum ).
Neurologic Manifestations
Toxoplasma gondii in an African crested porcupine (Hystrix cristata).
Otitis Media
Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia.
Ovarian Neoplasms
Inhibiting WNT Ligand Production for Improved Immune Recognition in the Ovarian Tumor Microenvironment.
Ovarian Neoplasms
Targeting the Wnt/?-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974.
Ovarian Neoplasms
Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion.
Pancreatic Neoplasms
Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
Pancreatic Neoplasms
PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers.
Pancreatic Neoplasms
Porcupine inhibitors: Novel and emerging anti-cancer therapeutics targeting the Wnt signaling pathway.
Pancreatic Neoplasms
Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis.
Parasitemia
Wnt Signaling Plays a Key Role in the Regulation of the Immune Response and Cardiac Damage during Trypanosoma cruzi Infection.
Parkinson Disease
LGK974, a PORCUPINE inhibitor, mitigates cytotoxicity in an in vitro model of Parkinson's disease by interfering with the WNT/?-CATENIN pathway.
Pentalogy of Cantrell
Co-occurrence of severe Goltz-Gorlin syndrome and pentalogy of Cantrell - Case report and review of the literature.
Pericarditis
Fungal pericarditis and endocarditis secondary to porcupine quill migration in a dog.
Peripheral Nervous System Diseases
Pharmacologic Inhibition of Porcupine, Disheveled, and ?-Catenin in Wnt Signaling Pathway Ameliorates Diabetic Peripheral Neuropathy in Rats.
Pleurisy
Disseminated pulmonary adiaspiromycosis in a crested porcupine (Hystrix cristata Linnaeus, 1758).
Pneumonia
Disseminated pulmonary adiaspiromycosis in a crested porcupine (Hystrix cristata Linnaeus, 1758).
Poxviridae Infections
Genomic Analysis of Novel Poxvirus Brazilian Porcupinepox Virus, Brazil, 2019.
Rabies
Porcupine quills in raccoons as an indicator of rabies, distemper, or both diseases: disease management implications.
Rabies
Submitter and technician observations, and animal rabies detection in Massachusetts, 1992-2006.
Rhinitis
Fatal Aspergillus flavus rhinitis with gastrointestinal gaseous distension in a Cape porcupine.
Rhinitis
Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia.
Sarcoma, Ewing
Inhibition of porcupine prolongs metastasis free survival in a mouse xenograft model of Ewing sarcoma.
Skin Diseases
An Xp11.23 deletion containing PORCN may also cause angioma serpiginosum, a cosmetic skin disease associated with extreme skewing of X-inactivation.
Squamous Cell Carcinoma of Head and Neck
Inhibition of CBP/?-catenin and porcupine attenuates Wnt signaling and induces apoptosis in head and neck carcinoma cells.
Stomach Neoplasms
Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/?-catenin pathway in gastric cancer.
Tenosynovitis
Use of tenoscopy for management of septic tenosynovitis caused by a penetrating porcupine quill in the synovial sheath surrounding the digital flexor tendons of a horse.
Tinea
DIAGNOSIS AND SUCCESSFUL TREATMENT OF A POTENTIALLY ZOONOTIC DERMATOPHYTOSIS CAUSED BY MICROSPORUM GYPSEUM IN A ZOO-HOUSED NORTH AMERICAN PORCUPINE (ERETHIZON DORSATUM).
Toxoplasmosis
Disseminated toxoplasmosis in a captive porcupine (Coendou mexicanus) from Costa Rica.
Toxoplasmosis
Fatal Systemic Toxoplasma gondii Infection in a Red Squirrel (Sciurus vulgaris), a Swinhoe's Striped Squirrel (Tamiops swinhoei) and a New World Porcupine (Erethizontidae sp.).
Toxoplasmosis
Serologic survey of Toxoplasma gondii in noncarnivorous free-ranging neotropical mammals in French Guiana.
Trypanosomiasis
[Studies on reservoirs and wild vectors of trypanosomiasis cruzi. XVI. Natural infection of a porcupine, Coendou insidiosus insidiosus (Kuhl, 1820) by a cruzi-like trypanosoma]
Tuberculosis
Systemic Bovine Tuberculosis in a Crested Porcupine (Hystrix cristata) in the Marche Region, Italy.
Tuberculosis, Bovine
Systemic Bovine Tuberculosis in a Crested Porcupine (Hystrix cristata) in the Marche Region, Italy.
Tubular Sweat Gland Adenomas
Syringocystadenoma papilliferum in a patient with focal dermal hypoplasia due to a novel PORCN mutation.
Ureteral Obstruction
Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis.
Ureteral Obstruction
Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.
[wnt protein] o-palmitoleoyl transferase deficiency
Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.
html completed