Reference on EC 2.3.1.239 - 10-deoxymethynolide synthase
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Lu, H.; Tsai, S.; Khosla, C.; Cane, D.
Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase
Biochemistry
41
12590-12597
2002
Streptomyces venezuelae
Kittendorf, J.D.; Beck, B.J.; Buchholz, T.J.; Seufert, W.; Sherman, D.H.
Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase
Chem. Biol.
14
944-954
2007
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1)
Tang, L.; Fu, H.; Betlach, M.C.; McDaniel, R.
Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase
Chem. Biol.
6
553-558
1999
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1), Streptomyces venezuelae
Yan, J.; Gupta, S.; Sherman, D.H.; Reynolds, K.A.
Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains
ChemBioChem
10
1537-1543
2009
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1), Streptomyces venezuelae, Streptomyces venezuelae ATCC 15439 (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1)
Yin, Y.; Lu, H.; Khosla, C.; Cane, D.E.
Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase
J. Am. Chem. Soc.
125
5671-5676
2003
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1), Streptomyces venezuelae ATCC 15439 (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1)
Aldrich, C.C.; Beck, B.J.; Fecik, R.A.; Sherman, D.H.
Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates
J. Am. Chem. Soc.
127
8441-8452
2005
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1)
Whicher, J.R.; Dutta, S.; Hansen, D.A.; Hale, W.A.; Chemler, J.A.; Dosey, A.M.; Narayan, A.R.; Hakansson, K.; Sherman, D.H.; Smith, J.L.; Skiniotis, G.
Structural rearrangements of a polyketide synthase module during its catalytic cycle
Nature
510
560-564
2014
Streptomyces venezuelae (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1), Streptomyces venezuelae, Streptomyces venezuelae ATCC 15439 (Q9ZGI5 and Q9ZGI4 and Q9ZGI3 and Q9ZGI2 and Q9ZGI1)
Chemler, J.A.; Tripathi, A.; Hansen, D.A.; ONeil-Johnson, M.; Williams, R.B.; Starks, C.; Park, S.R.; Sherman, D.H.
Evolution of efficient modular polyketide synthases by homologous recombination
J. Am. Chem. Soc.
137
10603-10609
2015
Streptomyces venezuelae, Streptomyces venezuelae ATCC 15439
Hansen, D.A.; Koch, A.A.; Sherman, D.H.
Substrate controlled divergence in polyketide synthase catalysis
J. Am. Chem. Soc.
137
3735-3738
2015
Streptomyces venezuelae, Streptomyces venezuelae ATCC 15439
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