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Reference on EC 2.3.1.199 - very-long-chain 3-oxoacyl-CoA synthase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dittrich, F.; Zajonc, D.; Huhne, K.; Hoja, U.; Ekici, A.; Greiner, E.; Klein, H.; Hofmann, J.; Bessoule, J.J.; Sperling, P.; Schweizer, E.
Fatty acid elongation in yeast. Biochemical characteristics of the enzyme system and isolation of elongation-defective mutants
Eur. J. Biochem.
252
477-485
1998
Saccharomyces cerevisiae, Saccharomyces cerevisiae X2180-1A
Manually annotated by BRENDA team
Blacklock, B.J.; Kelley, D.; Patel, S.
A fatty acid elongase ELO with novel activity from Dictyostelium discoideum
Biochem. Biophys. Res. Commun.
374
226-230
2008
Dictyostelium discoideum (Q54CJ4), Dictyostelium discoideum, Dictyostelium discoideum AX3 (Q54CJ4)
Manually annotated by BRENDA team
Sakuradani, E.; Nojiri, M.; Suzuki, H.; Shimizu, S.
Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4
Appl. Microbiol. Biotechnol.
84
709-716
2009
Mortierella alpina (C8KHM6), Mortierella alpina, Mortierella alpina 1S-4 (C8KHM6), Mortierella alpina 1S-4
Manually annotated by BRENDA team
Fujisawa, M.; Watanabe, M.; Choi, S.K.; Teramoto, M.; Ohyama, K.; Misawa, N.
Enrichment of carotenoids in flaxseed (Linum usitatissimum) by metabolic engineering with introduction of bacterial phytoene synthase gene crtB
J. Biosci. Bioeng.
105
636-641
2008
Crambe hispanica subsp. abyssinica (Q32VC2)
Manually annotated by BRENDA team
Blacklock, B.; Jaworski, J.
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases
Biochem. Biophys. Res. Commun.
346
583-590
2006
Arabidopsis thaliana
Manually annotated by BRENDA team
Kunst, L.; Clemens, S.; Hooker, T.
Expression of the wax-specific condensing enzyme CUT1 in Arabidopsis
Biochem. Soc. Trans.
28
651-654
2000
Arabidopsis thaliana
Manually annotated by BRENDA team
Ghanevati, M.; Jaworski, J.
Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS
Eur. J. Biochem.
269
3531-3539
2002
Arabidopsis thaliana
Manually annotated by BRENDA team
Katavic, V.; Barton, D.; Giblin, E.; Reed, D.; Kumar, A.; Taylor, D.
Gaining insight into the role of serine 282 in B. napus FAE1 condensing enzyme
FEBS Lett.
562
118-124
2004
Brassica napus
Manually annotated by BRENDA team
Toke, D.; Martin, C.
Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae
J. Biol. Chem.
271
18413-18422
1996
Saccharomyces cerevisiae, Saccharomyces cerevisiae W3031B
Manually annotated by BRENDA team
Oh, C.; Toke, D.; Mandala, S.; Martin, C.
ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation
J. Biol. Chem.
272
17376-17384
1997
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Qin, Y.; Pujol, F.; Hu, C.; Feng, J.; Kastaniotis, A.; Hiltunen, J.; Zhu, Y.
Genetic and biochemical studies in yeast reveal that the cotton fibre-specific GhCER6 gene functions in fatty acid elongation
J. Exp. Bot.
58
473-481
2007
Gossypium hirsutum (Q2QCW7), Gossypium hirsutum
Manually annotated by BRENDA team
Tresch, S.; Heilmann, M.; Christiansen, N.; Looser, R.; Grossmann, K.
Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases
Phytochemistry
76
162-171
2012
Arabidopsis thaliana, Lemna aequinoctialis
Manually annotated by BRENDA team
Millar, A.; Clemens, S.; Zachgo, S.; Michael Giblin, E.; Taylor, D.; Kunst, L.
CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme
Plant Cell
11
825-838
1999
Arabidopsis thaliana
Manually annotated by BRENDA team
Fiebig, A.; Mayfield, J.; Miley, N.; Chau, S.; Fischer, R.; Preuss, D.
Alterations in CER6, a gene identical to CUT1, differentially affect long-chain lipid content on the surface of pollen and stems
Plant Cell
12
2001-2008
2000
Arabidopsis thaliana (Q9XF43)
Manually annotated by BRENDA team
Reina-Pinto, J.; Voisin, D.; Kurdyukov, S.; Faust, A.; Haslam, R.; Michaelson, L.; Efremova, N.; Franke, B.; Schreiber, L.; Napier, J.; Yephremov, A.
Misexpression of fatty acid elongation1 in the Arabidopsis epidermis induces cell death and suggests a critical role for phospholipase A2 in this process
Plant Cell
21
1252-1272
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Millar, A.; Kunst, L.
Very-long-chain fatty acid biosynthesis is controlled through the expression and specificity of the condensing enzyme
Plant J.
12
121-131
1997
Arabidopsis thaliana
Manually annotated by BRENDA team
Todd, J.; Post-Beittenmiller, D.; Jaworski, J.
KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana
Plant J.
17
119-130
1999
Arabidopsis thaliana
Manually annotated by BRENDA team
Lee, S.; Jung, S.; Go, Y.; Kim, H.; Kim, J.; Cho, H.; Park, O.; Suh, M.
Two Arabidopsis 3-ketoacyl CoA synthase genes, KCS20 and KCS2/DAISY, are functionally redundant in cuticular wax and root suberin biosynthesis, but differentially controlled by osmotic stress
Plant J.
60
462-475
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Purdy, J.G.; Shenk, T.; Rabinowitz, J.D.
Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication
Cell Rep.
10
1375-1385
2015
Homo sapiens (A1L3X0), Homo sapiens
Manually annotated by BRENDA team
Sassa, T.; Ohno, Y.; Suzuki, S.; Nomura, T.; Nishioka, C.; Kashiwagi, T.; Hirayama, T.; Akiyama, M.; Taguchi, R.; Shimizu, H.; Itohara, S.; Kihara, A.
Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production
Mol. Cell. Biol.
33
2787-2796
2013
Mus musculus
Manually annotated by BRENDA team
Tsuda, K.; Akiba, T.; Kimura, F.; Ishibashi, M.; Moriya, C.; Nakagawa, K.; Kurata, N.; Ito, Y.
ONION2 fatty acid elongase is required for shoot development in rice
Plant Cell Physiol.
54
209-217
2013
Oryza sativa
Manually annotated by BRENDA team
Haslam, T.M.; Haslam, R.; Thoraval, D.; Pascal, S.; Delude, C.; Domergue, F.; Fernandez, A.M.; Beaudoin, F.; Napier, J.A.; Kunst, L.; Joubes, J.
ECERIFERUM2-LIKE proteins have unique biochemical and physiological functions in very-long-chain fatty acid elongation
Plant Physiol.
167
682-692
2015
Arabidopsis thaliana (Q9LIS1), Arabidopsis thaliana (Q9SVM9)
Manually annotated by BRENDA team
Yamauchi, T.; Shiono, K.; Nagano, M.; Fukazawa, A.; Ando, M.; Takamure, I.; Mori, H.; Nishizawa, N.K.; Kawai-Yamada, M.; Tsutsumi, N.; Kato, K.; Nakazono, M.
Ethylene biosynthesis is promoted by very-long-chain fatty acids during lysigenous aerenchyma formation in rice roots
Plant Physiol.
169
180-193
2015
Oryza sativa (Q10PV5), Oryza sativa
Manually annotated by BRENDA team
Naganuma, T.; Kihara, A.
Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle
PLoS ONE
9
e101823
2014
Homo sapiens (Q9H5J4)
Manually annotated by BRENDA team
Morais, S.; Mourente, G.; Martinez, A.; Gras, N.; Tocher, D.R.
Docosahexaenoic acid biosynthesis via fatty acyl elongase and DELTA4-desaturase and its modulation by dietary lipid level and fatty acid composition in a marine vertebrate
Biochim. Biophys. Acta
1851
588-597
2015
Solea senegalensis (G8IIS1)
Manually annotated by BRENDA team
Li, C.; Haslam, T.M.; Krueger, A.; Schneider, L.M.; Mishina, K.; Samuels, L.; Yang, H.; Kunst, L.; Schaffrath, U.; Nawrath, C.; Chen, G.; Komatsuda, T.; von Wettstein-Knowles, P.
The beta-ketoacyl-CoA synthase HvKCS1, encoded by Cer-zh, plays a key role in synthesis of barley leaf wax and germination of barley powdery mildew
Plant Cell Physiol.
59
806-822
2018
Hordeum vulgare
Manually annotated by BRENDA team
Wang, X.; Guan, Y.; Zhang, D.; Dong, X.; Tian, L.; Qu, L.Q.
A beta-ketoacyl-CoA synthase is involved in rice leaf cuticular wax synthesis and requires a CER2-LIKE protein as a cofactor
Plant Physiol.
173
944-955
2017
Oryza sativa Japonica Group (Q10PV5)
Manually annotated by BRENDA team