Reference on EC 2.3.1.191 - UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Albers, U.; Tiaden, A.; Spirig, T.; Al Alam, D.; Goyert, S.M.; Gangloff, S.C.; Hilbi, H.
Expression of Legionella pneumophila paralogous lipid A biosynthesis genes under different growth conditions
Microbiology
153
3817-3829
2007
Legionella pneumophila (Q5ZRD8), Legionella pneumophila (Q5ZY64), Legionella pneumophila
Vaara, M.; Nurminen, M.
Outer membrane permeability barrier in Escherichia coli mutants that are defective in the late acyltransferases of lipid A biosynthesis
Antimicrob. Agents Chemother.
43
1459-1462
1999
Escherichia coli
Bartling, C.M.; Raetz, C.R.
Steady-state kinetics and mechanism of LpxD, the N-acyltransferase of lipid A biosynthesis
Biochemistry
47
5290-5302
2008
Escherichia coli
Bartling, C.M.; Raetz, C.R.
Crystal structure and acyl chain selectivity of Escherichia coli LpxD, the N-acyltransferase of lipid A biosynthesis
Biochemistry
48
8672-8683
2009
Escherichia coli (P21645), Escherichia coli
Vuorio, R.; Hrknen, T.; Tolvanen, M.; Vaara, M.
The novel hexapeptide motif found in the acyltransferases LpxA and LpxD of lipid A biosynthesis is conserved in various bacteria
FEBS Lett.
337
289-292
1994
Yersinia enterocolitica (P32203)
Steeghs, L.; Jennings, M.P.; Poolman, J.T.; van der Ley, P.
Isolation and characterization of the Neisseria meningitidis lpxD-fabZ-lpxA gene cluster involved in lipid A biosynthesis
Gene
190
263-270
1997
Neisseria meningitidis (P95377)
Bainbridge, B.W.; Karimi-Naser, L.; Reife, R.; Blethen, F.; Ernst, R.K.; Darveau, R.P.
Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis
J. Bacteriol.
190
4549-4558
2008
Porphyromonas gingivalis, Escherichia coli
Kelly, T.M.; Stachula, S.A.
Raetz, C.R.; Anderson, M.S.: The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis
J. Biol. Chem.
268
19866-19874
1993
Escherichia coli
Buetow, L.; Smith, T.K.; Dawson, A.; Fyffe, S.; Hunter, W.N.
Structure and reactivity of LpxD, the N-acyltransferase of lipid A biosynthesis
Proc. Natl. Acad. Sci. USA
104
4321-4326
2007
Chlamydia trachomatis (P0CD76), Chlamydia trachomatis
Badger, J.; Chie-Leon, B.; Logan, C.; Sridhar, V.; Sankaran, B.; Zwart, P.H.; Nienaber, V.
The structure of LpxD from Pseudomonas aeruginosa at 1.3 A resolution
Acta Crystallogr. Sect. F
67
749-752
2011
Pseudomonas aeruginosa (Q9HXY6)
Jenkins, R.J.; Dotson, G.D.
A continuous fluorescent enzyme assay for early steps of lipid A biosynthesis
Anal. Biochem.
425
21-27
2012
Escherichia coli
Li, C.; Guan, Z.; Liu, D.; Raetz, C.R.
Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli
Proc. Natl. Acad. Sci. USA
108
11387-11392
2011
Arabidopsis thaliana (F4JGP6), Arabidopsis thaliana Col-0 (F4JGP6)
Li, Y.; Powell, D.A.; Shaffer, S.A.; Rasko, D.A.; Pelletier, M.R.; Leszyk, J.D.; Scott, A.J.; Masoudi, A.; Goodlett, D.R.; Wang, X.; Raetz, C.R.; Ernst, R.K.
LPS remodeling is an evolved survival strategy for bacteria
Proc. Natl. Acad. Sci. USA
109
8716-8721
2012
Francisella tularensis subsp. novicida, Francisella tularensis subsp. novicida U112
Badger, J.; Chie-Leon, B.; Logan, C.; Sridhar, V.; Sankaran, B.; Zwart, P.H.; Nienaber, V.
Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii
Acta Crystallogr. Sect. F
69
6-9
2013
Acinetobacter baumannii (B0VMV2), Acinetobacter baumannii SDF (B0VMV2)
Alshalchi, S.A.; Anderson, G.G.
Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa
Arch. Microbiol.
197
135-145
2015
Pseudomonas aeruginosa (Q02RB8), Pseudomonas aeruginosa UCBPP-PA14 (Q02RB8)
Yeom, D.H.; Kim, S.K.; Lee, M.N.; Lee, J.H.
Pleiotropic effects of acyltransferases on various virulence-related phenotypes of Pseudomonas aeruginosa
Genes Cells
18
682-693
2013
Pseudomonas aeruginosa (Q9HXY6), Pseudomonas aeruginosa
Eshghi, A.; Henderson, J.; Trent, M.S.; Picardeau, M.
Leptospira interrogans lpxD homologue is required for thermal acclimatization and virulence
Infect. Immun.
83
4314-4321
2015
Leptospira interrogans, Leptospira interrogans L495
Jenkins, R.J.; Heslip, K.A.; Meagher, J.L.; Stuckey, J.A.; Dotson, G.D.
Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis
J. Biol. Chem.
289
15527-15535
2014
Escherichia coli
Masoudi, A.; Raetz, C.R.; Zhou, P.; Pemble, C.W.
Chasing acyl carrier protein through a catalytic cycle of lipid A production
Nature
505
422-426
2014
Escherichia coli (P21645)
Emiola, A.; George, J.; Andrews, S.S.
A complete pathway model for lipid A biosynthesis in Escherichia coli
PLoS ONE
10
e0121216
2014
Escherichia coli
Ma, X.; Prathapam, R.; Wartchow, C.; Chie-Leon, B.; Ho, C.M.; De Vicente, J.; Han, W.; Li, M.; Lu, Y.; Ramurthy, S.; Shia, S.; Steffek, M.; Uehara, T.
Structural and biological basis of small molecule inhibition of Escherichia coli LpxD acyltransferase essential for lipopolysaccharide biosynthesis
ACS Infect. Dis.
6
1480-1489
2019
Escherichia coli (Q0P6M7)
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