Information on EC 2.3.1.170 - 6'-deoxychalcone synthase

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The expected taxonomic range for this enzyme is: Glycyrrhiza echinata

EC NUMBER
COMMENTARY hide
2.3.1.170
-
RECOMMENDED NAME
GeneOntology No.
6'-deoxychalcone synthase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
-
-
cyclization
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-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
flavonoid biosynthesis
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-
Flavonoid biosynthesis
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Biosynthesis of secondary metabolites
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SYSTEMATIC NAME
IUBMB Comments
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing)
Isoliquiritigenin is the precursor of liquiritigenin, a 5-deoxyflavanone.
CAS REGISTRY NUMBER
COMMENTARY hide
114308-23-5
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+
CoA + isoliquiritigenin + CO2 + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+
CoA + isoliquiritigenin + CO2 + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE