Disease on EC 2.2.1.1 - transketolase
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Acidosis, Lactic
Clinical and biochemical aspects of thiamine treatment for metabolic acidosis during total parenteral nutrition.
Acidosis, Lactic
Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.
Acquired Immunodeficiency Syndrome
Conserved residues are functionally distinct within transketolases of different species.
Acquired Immunodeficiency Syndrome
Thiamine deficiency and Wernicke's encephalopathy in AIDS.
Adenocarcinoma
Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action.
Adenocarcinoma
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
Adenocarcinoma
TKTL1 as a Prognostic Marker in Pancreatic Ductal Adenocarcinoma and Its Correlation with FDG-PET-CT.
Adenocarcinoma
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Adenocarcinoma
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Adenoma
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
Adenoma
[Glucose-6-phosphate dehydrogenase and transketolase activity in the blood of neurological oncologic patients preoperatively and in the dynamics of the postoperative period]
Alcoholic Neuropathy
Erythrocyte transketolase activity in patients with diabetic and alcoholic neuropathies.
Alzheimer Disease
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Alzheimer Disease
Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease.
Alzheimer Disease
Cysteine proteinases are responsible for characteristic transketolase alterations in Alzheimer fibroblasts.
Alzheimer Disease
Effects of magnesium, high energy phosphates, piracetam and thiamin on erythrocyte transketolase.
Alzheimer Disease
In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells.
Alzheimer Disease
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Alzheimer Disease
Occurrence of transketolase abnormalities in extracts of foreskin fibroblasts from patients with Alzheimer's disease.
Alzheimer Disease
Properties and functions of the thiamin diphosphate dependent enzyme transketolase.
Alzheimer Disease
Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease.
Aneurysm
[Enzyme activity in post-infarct aneurysm and in the myocardial zone outside the infarct in experimental infarct in rats]
Arthritis, Rheumatoid
Sialic acid, transketolase and Na+, K+, ATPase in patients with rheumatoid arthritis.
Aspergillosis
Statistical analysis of pentose phosphate pathway genes from eubacteria and eukarya reveals translational selection as a major force in shaping codon usage pattern.
Astrocytoma
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Ataxia
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
Avitaminosis
Water soluble vitamins in chronic hemodialysis patients and need for supplementation.
Avitaminosis
[Blood transketolase activity and the TDP effect as indices of thiamine body allowance]
Avitaminosis
[Content of free and bound thiamine diphosphate in the liver hyaloplasm of vitamine B1 deficient rats]
Avitaminosis
[Enzyme activity of thiamine diphosphate biosynthesis and degradation in the mouse liver in the dynamics of B1 avitaminosis development]
Avitaminosis
[Experimental evaluation of the effectiveness of vitamin-enriched chopped meat products]
Avitaminosis
[The transketolase activity in erythrocytes as a criterion for thiamine balance in the body]
Beriberi
Blood vitamin B1, transketolase and thiamine pyrophosphate (TPP) effect in beriberi patients, with studies employing discriminant analysis.
Beriberi
Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi.
Beriberi
Erythrocyte transketolase activity, markers of cardiac dysfunction and the diagnosis of infantile beriberi.
Brain Diseases
Amprolium poisoning of preruminant lambs: an investigation of the encephalopathy and the haemorrhagic and diarrhoeic syndromes.
Breast Neoplasms
Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome.
Breast Neoplasms
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Breast Neoplasms
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
Breast Neoplasms
The thiamin status of early cancer patients with particular reference to those with breast and bronchial carcinomas.
Breast Neoplasms
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Breast Neoplasms
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Carcinogenesis
Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?
Carcinogenesis
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Carcinogenesis
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
Carcinogenesis
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Carcinogenesis
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Carcinogenesis
Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides.
Carcinogenesis
Transketolase like 1 (TKTL1) expression alterations in prostate cancer tumorigenesis.
Carcinoma
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
Carcinoma
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
Carcinoma
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Carcinoma
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Carcinoma
Identification of potential canine mammary tumour cell biomarkers using proteomic approach: Differences in protein profiles among tumour and normal mammary epithelial cells by two-dimensional electrophoresis-based mass spectrometry.
Carcinoma
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas.
Carcinoma
Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells.
Carcinoma
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
Carcinoma
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Carcinoma
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Carcinoma
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Carcinoma
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Carcinoma
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Carcinoma
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Carcinoma, Hepatocellular
A Correlative Study Between IVIM-DWI Parameters and the Expression Levels of Ang-2 and TKT in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Carcinoma, Hepatocellular
Effects of vitamins B1, B2, B6 and C on erythrocyte enzymes in South African Bantu.
Carcinoma, Hepatocellular
Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver.
Carcinoma, Hepatocellular
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Carcinoma, Hepatocellular
Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
Carcinoma, Hepatocellular
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Carcinoma, Hepatocellular
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Carcinoma, Intraductal, Noninfiltrating
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Carcinoma, Non-Small-Cell Lung
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase.
Carcinoma, Non-Small-Cell Lung
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
Carcinoma, Non-Small-Cell Lung
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Carcinoma, Squamous Cell
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Carcinoma, Squamous Cell
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas.
Carcinoma, Squamous Cell
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Carcinoma, Squamous Cell
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
Carcinosarcoma
[Level of thiamine diphosphate in the liver of tumor-bearing animals kept on a diet including an excessive amount of vitamin B 1]
Cataract
Changes in glutathione, glutathione-linked enzymes and hexose monophosphate shunt enzymes in senile cataract.
Colonic Neoplasms
Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29.
Colonic Neoplasms
The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
Colorectal Neoplasms
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
Colorectal Neoplasms
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Colorectal Neoplasms
Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer.
Colorectal Neoplasms
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Colorectal Neoplasms
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Colorectal Neoplasms
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Colorectal Neoplasms
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Confusion
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Crohn Disease
Erythrocyte transketolase deficiency in patients suffering from Crohn's disease.
Cysts
Univariate and classification analysis reveals potential diagnostic biomarkers for early stage ovarian cancer Type 1 and Type 2.
Deficiency Diseases
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
Dehydration
Proteomic analyses unraveling water stress response in two Eucalyptus species originating from contrasting environments for aridity.
Dehydration
Sweet siblings with different faces: the mechanisms of FBP and F6P aldolase, transaldolase, transketolase and phosphoketolase revisited in light of recent structural data.
Dementia
The activation of red blood cell transketolase in groups of patients especially at risk from thiamin deficiency.
Dermatitis, Contact
[Enzymatic activity of the pentosephosphate pathway of carbohydrate conversion in the experimental therapy of dermatitis in rats]
Diabetes Complications
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
Diabetes Complications
Thiamine status in patients undergoing lower extremity amputation due to diabetic foot lesion.
Diabetes Mellitus
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Diabetes Mellitus
[Thiamine content and transketolase activity in organs of albino rats with diabetes mellitus]
Diabetes Mellitus, Experimental
Effect of alloxan diabetes and cortisol on glucose-6-phosphate dehydrogenase and transketolase in rabbit liver mitochondria.
Diabetes Mellitus, Type 2
Might genetics play a role in understanding and treating diabetic polyneuropathy?
Diabetic Nephropathies
Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality.
Diabetic Nephropathies
Role of thiamine status and genetic variability in transketolase and other pentose phosphate cycle enzymes in the progression of diabetic nephropathy.
Diabetic Neuropathies
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
Diabetic Neuropathies
The correlation between the activation coefficient of erythrocyte transketolase activity and diabetic neuropathy.
Diabetic Retinopathy
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy.
Diabetic Retinopathy
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Drug Eruptions
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Echinococcosis
[Cloning, expression and immunity analysis of transketolase of Echinococcus granulosus].
Endometrial Neoplasms
Expression of transketolase-like 1 protein (TKTL1) in human endometrial cancer.
Esophageal Neoplasms
Transketolase Serves a Poor Prognosticator in Esophageal Cancer by Promoting Cell Invasion via Epithelial-Mesenchymal Transition.
Esophageal Squamous Cell Carcinoma
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Fibromyalgia
Effects of magnesium, high energy phosphates, piracetam and thiamin on erythrocyte transketolase.
Gastroesophageal Reflux
Multiple causes of asphyxia in infants at high risk for sudden infant death.
Genetic Diseases, Inborn
Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.
Glioblastoma
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Glioma
Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis.
Glucosephosphate Dehydrogenase Deficiency
Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis.
Glycogen Storage Disease Type I
[Transketolase and transaldolase in the liver in Gierke's disease.]
Granulosa Cell Tumor
Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF.
Head and Neck Neoplasms
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation.
Heart Diseases
Blood transketolase activity in beriberi heart disease. A useful diagnostic index.
Heart Diseases
[Transketolase activity in rabbit myocardium and erythrocytes in health and in allergic heart diseases]
Hepatic Insufficiency
The influence of hepatic insufficiency due to alcoholic cirrhosis on the erythrocyte transketolase activity (ETKA).
Herpes Zoster
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Hyperglycemia
Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease.
Hyperglycemia
Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats.
Hypokinesia
[Several indicators of protein and nucleic acid metabolism in lymphoid organs of rats exposed to hypokinesia and vitamin B1 deficiency]
Infections
Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses.
Infections
Transketolase of Staphylococcus aureus is involved in the control of master regulators of stress response during infection.
Infections
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
Inflammatory Bowel Diseases
TKT maintains intestinal ATP production and inhibits apoptosis-induced colitis.
Influenza in Birds
Antigenic characterization of recent H5N1 highly pathogenic avian influenza viruses circulating in Egyptian poultry.
Influenza in Birds
Development of Clade-Specific and Broadly Reactive Live Attenuated Influenza Virus Vaccines against Rapidly Evolving H5 Subtype Viruses.
Influenza in Birds
Different counteracting host immune responses to clade 2.2.1.1 and 2.2.1.2 Egyptian H5N1 highly pathogenic avian influenza viruses in naïve and vaccinated chickens.
Influenza in Birds
Pathogenicity of the Egyptian A/H5N1 avian influenza viruses in chickens.
Influenza in Birds
Re-Emergence of a Novel H5N1 Avian Influenza Virus Variant Subclade 2.2.1.1 in Egypt During 2014.
Influenza in Birds
Variation in protection of four divergent avian influenza virus vaccine seed strains against eight clade 2.2.1 and 2.2.1.1. Egyptian H5N1 high pathogenicity variants in poultry.
Insulinoma
Detection Of Transketolase In Bone Marrow-Derived Insulin Producing Cells: Benfotiamine Enhances Insulin Synthesis And Glucose Metabolism.
Kidney Failure, Chronic
Comparison of the thiamine level in blood and erythrocyte transketolase activity in hemodialyzed and nondialyzed patients during recombinant human erythropoietin therapy.
Kidney Failure, Chronic
High thiamine diphosphate concentrations in erythrocytes can be achieved in dialysis patients by oral administration of benfontiamine.
Kidney Failure, Chronic
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity.
Kidney Failure, Chronic
[Catalytic activity of transketolase in erythrocytes in chronic kidney failure]
Kidney Failure, Chronic
[The effect of cocarboxylase treatment on erythrocyte transketolase and blood thiamine in patients with end stage renal disease undergoing maintenance hemodialysis]
Korsakoff Syndrome
A biochemical abnormality of transketolase in patients with Wernicke-Korsakoff syndrome.
Korsakoff Syndrome
A transketolase assembly defect in a Wernicke-Korsakoff syndrome patient.
Korsakoff Syndrome
An enzymatic and immunochemical analysis of transketolase in fibroblasts from Wernicke-Korsakoff syndrome.
Korsakoff Syndrome
An erythrocyte transketolase isoenzyme pattern associated with the Wernicke-Korsakoff syndrome.
Korsakoff Syndrome
Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals.
Korsakoff Syndrome
Effect of chronic alcohol administration on transketolase in the brain and the liver of rats.
Korsakoff Syndrome
Molecular genetics of transketolase in the pathogenesis of the Wernicke-Korsakoff syndrome.
Korsakoff Syndrome
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Korsakoff Syndrome
Nucleotide and predicted amino acid sequence of a cDNA clone encoding part of human transketolase.
Korsakoff Syndrome
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
Korsakoff Syndrome
Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.
Leigh Disease
Erythrocyte transketolase activity in suspected cases of Leigh's disease, or subacute necrotising encephalomyelopathy.
Leiomyoma
Glucose metabolism of malignant cells is not regulated by transketolase-like (TKTL)-1.
Liver Cirrhosis, Alcoholic
The influence of hepatic insufficiency due to alcoholic cirrhosis on the erythrocyte transketolase activity (ETKA).
Liver Diseases
Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
Liver Diseases
Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure.
Lung Neoplasms
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase.
Lung Neoplasms
Effect of siRNA-mediated gene silencing of transketolase on A549 lung cancer cells.
Lung Neoplasms
Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression.
Lung Neoplasms
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Lymphatic Metastasis
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
Lymphatic Metastasis
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
Lymphatic Metastasis
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Magnesium Deficiency
Effect of magnesium deficiency on blood and liver transketolase activity and on the recovery of enzyme activity in thiamine-deficient rats receiving thiamine.
Malaria
Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi.
Malaria
Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment.
Malnutrition
Red cell transketolase as an indicator of nutritional deficiency.
Malnutrition
The age dependence of the activity and activation of human red blood cell transketolase.
Melanoma
Exchange reactions catalyzed by group-transferring enzymes oppose the quantitation and the unravelling of the identify of the pentose pathway.
Melanoma
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.
Metabolism, Inborn Errors
Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects.
Metabolism, Inborn Errors
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
Mitral Valve Stenosis
[Activity of enzymes of pentosephosphate pathway in the erythrocytes, myocardium and intercostal muscle of patients with mitral valve stenosis]
Multiple Sclerosis
Transketolase and 2',3'-cyclic-nucleotide 3'-phosphodiesterase type I isoforms are specifically recognized by IgG autoantibodies in multiple sclerosis patients.
Muscular Dystrophies
[On the glucose-6-phosphate dehydrogenase and transketolase activities in the serum of subjects with progressive muscular dystrophy.]
Myocardial Infarction
[Thiamine metabolism and transketolase activity of tissues in experimental myocardial infarct]
Myocarditis
[Use of glucose-6-phosphate dehydrogenase and transketolase for characterization of pathologic processes in the myocardium in rheumatism]
Nasopharyngeal Carcinoma
Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate.
Nasopharyngeal Carcinoma
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Retraction. Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Nasopharyngitis
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
Nasopharyngitis
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Neoplasm Metastasis
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
Neoplasm Metastasis
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Neoplasm Metastasis
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
Neoplasm Metastasis
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Neoplasm Metastasis
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Neoplasm Metastasis
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Neoplasm Metastasis
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland.
Neoplasm Metastasis
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
Neoplasm Metastasis
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
Neoplasm Metastasis
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Neoplasm Metastasis
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Neoplasm Metastasis
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Neoplasm Metastasis
Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report.
Neoplasm Metastasis
[Effects of transketolase-like gene TKTL1 on occurrence and metastasis of human nasopharyngeal carcinoma]
Neoplasm Metastasis
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Neoplasms
A ?38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activity.
Neoplasms
A first immunohistochemistry study of transketolase and transketolase-like 1 expression in canine hyperplastic and neoplastic mammary lesions.
Neoplasms
Activities of enzymes of the hexose monophosphate pathway in nervous system tumors induced by ethylnitrosourea.
Neoplasms
Amplification of the transketolase gene in desensitization-resistant mutant Y1 mouse adrenocortical tumor cells.
Neoplasms
Antitumor activity of hydroxythiamine and methotrexate immobilized on monocarboxycellulose.
Neoplasms
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Neoplasms
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.
Neoplasms
Computer modeling of transketolase-like protein, TKTL1, a marker of certain tumor tissues.
Neoplasms
Differential protein expression in honeybee (Apis mellifera L.) larvae: underlying caste differentiation.
Neoplasms
Dual effects for lovastatin in anaplastic thyroid cancer: the pivotal effect of transketolase (TKT) on lovastatin and tumor proliferation.
Neoplasms
EDIM-TKTL1 blood test: a noninvasive method to detect upregulated glucose metabolism in patients with malignancies.
Neoplasms
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
Neoplasms
Effect of radical prostatectomy on levels of cancer related epitopes in circulating macrophages of patients with clinically localized prostate cancer.
Neoplasms
Enhanced TKTL1 Expression in Malignant Tumors of the Ocular Adnexa Predicts Clinical Outcome.
Neoplasms
Evaluation of a biomarker based blood test for monitoring surgical resection of oral squamous cell carcinomas.
Neoplasms
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Neoplasms
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
Neoplasms
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
Neoplasms
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
Neoplasms
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Neoplasms
Expression of transketolase-like gene 1 (TKTL1) depends on disease phase in patients with chronic myeloid leukaemia (CML).
Neoplasms
Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
Neoplasms
Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation.
Neoplasms
Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF.
Neoplasms
Glucose metabolism of malignant cells is not regulated by transketolase-like (TKTL)-1.
Neoplasms
Glucose transporter GLUT1 expression is an stage-independent predictor of clinical outcome in adrenocortical carcinoma.
Neoplasms
Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
Neoplasms
Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides.
Neoplasms
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases.
Neoplasms
Homology modeling of human transketolase: description of critical sites useful for drug design and study of the cofactor binding mode.
Neoplasms
Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer.
Neoplasms
Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay.
Neoplasms
Identification of potential canine mammary tumour cell biomarkers using proteomic approach: Differences in protein profiles among tumour and normal mammary epithelial cells by two-dimensional electrophoresis-based mass spectrometry.
Neoplasms
Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming.
Neoplasms
In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells.
Neoplasms
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Neoplasms
Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
Neoplasms
Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Neoplasms
Knockdown of TKTL1 additively complements cisplatin-induced cytotoxicity in nasopharyngeal carcinoma cells by regulating the levels of NADPH and ribose-5-phosphate.
Neoplasms
Long Noncoding RNA TSLNC8 Is a Tumor Suppressor that Inactivates the IL-6/STAT3 Signaling Pathway.
Neoplasms
Mechanical insights of oxythiamine compound as potent inhibitor for human transketolase-like protein 1 (TKTL1 protein).
Neoplasms
Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer.
Neoplasms
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Neoplasms
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
Neoplasms
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma.
Neoplasms
Oxythiamine and dehydroepiandrosterone induce a G1 phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle.
Neoplasms
Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation.
Neoplasms
Population thiamine status and varying cancer rates between western, Asian and African countries.
Neoplasms
Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response.
Neoplasms
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland.
Neoplasms
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
Neoplasms
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.
Neoplasms
The development of tumours under a ketogenic diet in association with the novel tumour marker TKTL1: A case series in general practice.
Neoplasms
The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study.
Neoplasms
The human transketolase-like proteins TKTL1 and TKTL2 are bona fide transketolases.
Neoplasms
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
Neoplasms
The role of thiamine in cancer: possible genetic and cellular signaling mechanisms.
Neoplasms
The thiamine status of patients with cancer as determined by the red cell transketolase activity.
Neoplasms
TKTL1 expression and its downregulation is implicated in cell proliferation inhibition and cell cycle arrest in esophageal squamous cell carcinoma.
Neoplasms
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Neoplasms
TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Neoplasms
TKTL1 modulates the response of paclitaxel-resistant human ovarian cancer cells to paclitaxel.
Neoplasms
TKTL1 promotes cell proliferation and metastasis in esophageal squamous cell carcinoma.
Neoplasms
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Neoplasms
Transketolase regulates the metabolic switch to control breast cancer cell metastasis via the alpha-ketoglutarate signaling pathway.
Neoplasms
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells.
Neoplasms
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Neoplasms
Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.
Neoplasms
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Neoplasms
Transketolase-like protein 1 expression in recurrent oral squamous cell carcinoma after curative resection: a case report.
Neoplasms
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer.
Neoplasms
Tumor-associated metabolic and inflammatory responses in early stage non-small cell lung cancer: Local patterns and prognostic significance.
Neoplasms
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Neoplasms
[Analysis of differentially expressed lung metastasis-associated proteins in adenoid cystic carcinoma cell lines]
Neoplasms
[Effect of thiamine and its antimetabolite oxythiamine on the proliferative activity of carcinosarcoma Walker 256 cells]
Neoplasms
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Neoplasms
[The effect of oxythiamine on tumor growth and certain biochemical and genetic characteristics of normal and tumor cells]
Neoplasms
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Neoplasms, Experimental
[Thiamine content of tissues, activity of transketolase and development of experimental neoplasms with different thiamine allowances]
Nervous System Diseases
Occurrence of transketolase abnormalities in extracts of foreskin fibroblasts from patients with Alzheimer's disease.
Neuroblastoma
Sensitivity to thiamine deficiency in cultured human cells is dependent on cell type and is enhanced in cells from thiamine-responsive megaloblastic anemia patients.
Neurodegenerative Diseases
Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Nutrition Disorders
BLOOD TRANSKETOLASE DETERMINATION IN NUTRITIONAL DISORDERS OF THE NERVOUS SYSTEM.
Obesity
Attenuated metabolism is a hallmark of obesity as revealed by comparative proteomic analysis of human omental adipose tissue.
Obesity
Fasting in obesity. Thiamine depletion as measured by erythrocyte transketolase changes.
Obesity
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
Ovarian Neoplasms
TKTL1 modulates the response of paclitaxel-resistant human ovarian cancer cells to paclitaxel.
Ovarian Neoplasms
Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation.
Ovarian Neoplasms
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Pancreatic Neoplasms
Fructose induces transketolase flux to promote pancreatic cancer growth.
Pancreatic Neoplasms
Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
Pancreatic Neoplasms
Inhibition of transketolase by oxythiamine altered dynamics of protein signals in pancreatic cancer cells.
Parasitic Diseases
The vitamin B1 status among young Egyptian males in relation to infection with parasites.
Peripheral Nervous System Diseases
The haematic thiamine level in the course of alcoholic neuropathy.
Peripheral Nervous System Diseases
Transketolase inhibition and uremic peripheral sensory neuropathy.
Polyneuropathies
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
Primary Dysautonomias
Altered Heavy Metals and Transketolase Found in Autistic Spectrum Disorder.
Primary Dysautonomias
The role of trace elements, thiamin (e) and transketolase in autism and autistic spectrum disorder.
Prostatic Neoplasms
Effect of radical prostatectomy on levels of cancer related epitopes in circulating macrophages of patients with clinically localized prostate cancer.
Prostatic Neoplasms
Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients.
Prostatic Neoplasms
Transketolase like 1 (TKTL1) expression alterations in prostate cancer tumorigenesis.
Protein-Energy Malnutrition
Erythrocyte transketolase activity in protein-energy malnutrition.
Psoriasis
[On methods for determination of transketolase in the skin of patients with psoriasis]
Psoriasis
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Rectal Neoplasms
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
Renal Insufficiency, Chronic
Erythrocyte transketolase activity in patients with chronic renal disease.
Rheumatic Diseases
[Use of glucose-6-phosphate dehydrogenase and transketolase for characterization of pathologic processes in the myocardium in rheumatism]
Riboflavin Deficiency
Effect of simultaneous thiamin and riboflavin deficiencies on the determination of transketolase and glutathione reductase.
Sarcoma
High-performance liquid chromatography/nano-electrospray ionization tandem mass spectrometry, two-dimensional difference in-gel electrophoresis and gene microarray identification of lymphatic metastasis-associated biomarkers.
Sarcoma
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Seizures
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
Skin Diseases
[Transketolase activity as a parameter for the vitamin B1 provision in some dermatoses (herpes zoster, psoriasis, drug eruptions, excema, and urticaria) (author's transl)]
Squamous Cell Carcinoma of Head and Neck
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation.
Squamous Cell Carcinoma of Head and Neck
EDIM-TKTL1/Apo10 Blood Test: An Innate Immune System Based Liquid Biopsy for the Early Detection, Characterization and Targeted Treatment of Cancer.
Squamous Cell Carcinoma of Head and Neck
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Squamous Cell Carcinoma of Head and Neck
Transketolase-like protein 1 confers resistance to serum withdrawal in vitro.
Starvation
Action of thiamine on protein and nucleic acid metabolism, III. Transketolase activity of Lactobacillus viridescens during thiamine starvation.
Starvation
Behavior of transaldolase (EC 2.2.1.2) and transketolase (EC 2.2.1.1) Activities in normal, neoplastic, differentiating, and regenerating liver.
Stomach Neoplasms
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Stomach Neoplasms
Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
Stomach Neoplasms
TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients.
Stomach Neoplasms
Transketolase-Like Protein 1 and Glucose Transporter 1 in Gastric Cancer.
Stomach Neoplasms
[Transketolase activity and thiamine diphosphate content in oncological patients]
Thiamine Deficiency
Abnormalities of peripheral nerve conduction in relation to thiamine status in alcoholic patients.
Thiamine Deficiency
Absorption, utilization and clinical effectiveness of allithiamines compared to water-soluble thiamines.
Thiamine Deficiency
Acute encephalopathy due to thiamine deficiency (Wernicke's encephalopathy) in a chronic hemodialyzed patient: a case report.
Thiamine Deficiency
Alcohol intakes and deficiencies in thiamine and vitamin B6 in black patients with cardiac failure.
Thiamine Deficiency
Chronic toxicity of dichloroacetate: possible relation to thiamine deficiency in rats.
Thiamine Deficiency
Clinical evaluation and biochemical analyses of thiamine deficiency in Pacific harbor seals (Phoca vitulina) maintained at a zoological facility.
Thiamine Deficiency
Clinical relevance of thiamine status amongst hospitalized elderly patients.
Thiamine Deficiency
Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals.
Thiamine Deficiency
Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency.
Thiamine Deficiency
Detection and incidence of B and C vitamin deficiency in alcohol-related illness.
Thiamine Deficiency
Downregulation of transketolase activity is related to inhibition of hippocampal progenitor cell proliferation induced by thiamine deficiency.
Thiamine Deficiency
Effect of peroral thiamine treatment on thiamine contents and transketolase activity of red blood cells in alcoholic patients.
Thiamine Deficiency
Effect of thiamine deficiency on gluconeogenesis and transketolase activity in isolated hepatocytes.
Thiamine Deficiency
Effects of thiamine deficiency and of oxythiamine on rat tissue transketolase.
Thiamine Deficiency
Glycolytic metabolism in cultured cells of the nervous system. IV. The effects of thiamine deficiency on thiamine levels, metabolites and thiamine-dependent enzymes on the C-6 glioma and C-1300 neuroblastoma cell lines.
Thiamine Deficiency
In thiamine deficiency, activation of erythrocyte transketolase by thiamine in vivo exceeds activation by cofactor in vitro.
Thiamine Deficiency
Individual susceptibility to Wernicke-Korsakoff syndrome and alcoholism-induced cognitive deficit: impaired thiamine utilization found in alcoholics and alcohol abusers.
Thiamine Deficiency
Lead induced thiamine deficiency in the brain decreased the threshold of electroshock seizure in rat.
Thiamine Deficiency
Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula.
Thiamine Deficiency
Peripheral neuropathy and myopathy. An experimental study of rats on alcohol and variable dietary thiamine.
Thiamine Deficiency
Polioencephalomalacia (cerebrocortical necrosis) induced by experimental thiamine deficiency in lambs.
Thiamine Deficiency
Reduced activities of thiamine-dependent enzymes in brains of alcoholics in the absence of Wernicke's encephalopathy.
Thiamine Deficiency
Reduced sensory and motor nerve conduction velocities in moderate drinkers.
Thiamine Deficiency
Shoshin Beriberi Mimicking a High-risk Non-ST-Segment Elevation Acute Coronary Syndrome with Cardiogenic Shock: When the Arteries are Not Guilty.
Thiamine Deficiency
The effect of thiaminase-induced subclinical thiamine deficiency on growth of weaner sheep.
Thiamine Deficiency
The relationship between erythrocyte transketolase activity and the 'TPP effect' in Wernicke's encephalopathy and other thiamine deficiency states.
Thiamine Deficiency
The thiamine-dependent hysteretic behavior of human transketolase: implications for thiamine deficiency.
Thiamine Deficiency
The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity.
Thiamine Deficiency
Thiamine deficiency decreases steady-state transketolase and pyruvate dehydrogenase but not alpha-ketoglutarate dehydrogenase mRNA levels in three human cell types.
Thiamine Deficiency
Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation.
Thiamine Deficiency
Thiamine pyrophosphate effect and normalized erythrocyte transketolase activity ratio in Wernicke-Korsakoff patients and acute alcoholics undergoing detoxification.
Thiamine Deficiency
Thiamine pyrophosphate-requiring enzymes are altered during pyrithiamine-induced thiamine deficiency in cultured human lymphoblasts.
Thiamine Deficiency
Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy.
Thiamine Deficiency
Thiamine utilization in the pathogenesis of alcohol-induced brain damage.
Thiamine Deficiency
Transketolase abnormality in cultured fibroblasts from familial chronic alcoholic men and their male offspring.
Thiamine Deficiency
TRANSKETOLASE ACTIVITY IN EXPERIMENTAL THIAMINE DEFICIENCY AND HEPATIC NECROSIS.
Thiamine Deficiency
Transketolase activity in the blood of cattle and sheep in relation to thiamine deficiency.
Thiamine Deficiency
Transketolase activity of blood hemolysate, a useful index for diagnosing thiamine deficiency.
Thiamine Deficiency
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study.
Thiamine Deficiency
[Analysis of the daily human requirements for thiamine in the newly arrived population of Polar regions]
Thiamine Deficiency
[Enzyme-histochemical behaviour of the tanycyte ependyma in the III. ventricle of the rat with thiamin deficiency (author's transl)]
Thiamine Deficiency
[Importance of water-soluble vitamins as regulatory factors of genetic expression]
Thiamine Deficiency
[Interstitial thiamine redistribution during the development of vitamin B1 deficiency in mice]
Thiamine Deficiency
[Thiamine deficiency in chronic alcoholism. The effect of thiamine treatment on the erythrocyte transketolase activity and the thiamine pyrophosphate effect]
Thiamine Deficiency
[Transketolase activity and the TDP effect in tissues of animals with experimental tumors]
Thiamine Deficiency
[Transketolase activity in thiamine deficiency of the kidney in rainbow trout (Salmo gairdneri) following continous feeding with raw hearring]
Thiamine Deficiency
[Transketolase activity of erythrocytes of chronic alcoholic patients with assumed thiamine deficiency]
Thiamine Deficiency
[Transketolase test: a means for the diagnosis of subclinical and clinical thiamine deficiency in cattle]
Thiamine Deficiency
[Ultrastructure of the rat gastric mucosal parietal cells in thiamine deficiency]
Thiamine Deficiency
[Use of the colorimetric micromethod for determination of erythrocyte transketolase activity in the enzyme test for detection of thiamine deficiency]
Thiamine Deficiency
[Vitamin B 1 deficiency in chronic alcoholics and its clinical correlation]
Thyroid Cancer, Papillary
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Thyroid Carcinoma, Anaplastic
Dual effects for lovastatin in anaplastic thyroid cancer: the pivotal effect of transketolase (TKT) on lovastatin and tumor proliferation.
Thyroid Neoplasms
Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.
Thyroid Neoplasms
Targeting the pentose phosphate pathway increases reactive oxygen species and induces apoptosis in thyroid cancer cells.
transaldolase deficiency
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
transketolase deficiency
Erythrocyte transketolase deficiency in patients suffering from Crohn's disease.
transketolase deficiency
Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects.
transketolase deficiency
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
transketolase deficiency
Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides.
transketolase deficiency
Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.
Tuberculosis
Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system.
Tuberculosis
Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy.
Tuberculosis
Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme.
Tuberculosis
Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase.
Tuberous Sclerosis
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Uremia
Comparison of the thiamine level in blood and erythrocyte transketolase activity in hemodialyzed and nondialyzed patients during recombinant human erythropoietin therapy.
Uremia
Erythrocyte transketolase activity in dialyzed patients. A reversible metabolic lesion of uremia.
Uremia
Water soluble vitamins in chronic hemodialysis patients and need for supplementation.
Urinary Bladder Neoplasms
Expression patterns and prognostic role of transketolase-like 1 in muscle-invasive bladder cancer.
Uterine Cervical Neoplasms
MicroRNA-497 regulates cisplatin chemosensitivity of cervical cancer by targeting transketolase.
Uterine Cervical Neoplasms
Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer.
Virus Diseases
Cross-protective efficacy of bivalent recombinant baculoviral vaccine against heterologous influenza H5N1 challenge.
Virus Diseases
[Metabolic aspects of hepatic tissue in MHV-3 virus infections of the mouse. I. Transketolase, glucose-6-phosphate-dehydrogenase, 6-phosphogluconic-dehydrogenase.]
Vitamin B 6 Deficiency
Detection and incidence of B and C vitamin deficiency in alcohol-related illness.
Wernicke Encephalopathy
Alcohol-thiamine interactions: an update on the pathogenesis of Wernicke encephalopathy.
Wernicke Encephalopathy
Current progress toward the prevention of the Wernicke-Korsakoff syndrome.
Wernicke Encephalopathy
The relationship between erythrocyte transketolase activity and the 'TPP effect' in Wernicke's encephalopathy and other thiamine deficiency states.
Wernicke Encephalopathy
Transketolase abnormality in tolazamide-induced Wernicke's encephalopathy.
Wernicke Encephalopathy
Wernicke's Encephalopthy Associated with Hyperemesis Gravidarum - A Case Report.
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