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Reference on EC 2.1.1.74 - methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Delk, A.S.; Romeo, J.M.; Nagle, D.P.; Rabinowitz, J.C.
Biosynthesis of ribothymidine in the transfer RNA of Streptococcus faecalis and Bacillus subtilis. A methylation of RNA involving 5,10-methylenetetrahydrofolate
J. Biol. Chem.
251
7649-7656
1976
Bacillus subtilis, Enterococcus faecalis, no activity in Micrococcus luteus
Manually annotated by BRENDA team
Delk, A.S.; Nagle, D.P.; Rabinowitz, J.C.
The methylenetetrahydrofolate-mediated biosynthesis of ribothymidine in the transfer-RNA of Streptococcus faecalis: incorporation of hydrogen from solvent into the methyl moiety
Biochem. Biophys. Res. Commun.
86
244-251
1979
Bacillus cereus, Bacillus subtilis, Enterococcus faecalis
Manually annotated by BRENDA team
Delk, A.S.; Nagle, D.P.; Rabinowitz, J.C.
Methylenetetrahydrofolate-dependent biosynthesis of ribothymidine in transfer RNA of Streptococcus faecalis. Evidence for reduction of the 1-carbon unit by FADH2
J. Biol. Chem.
255
4387-4390
1980
Bacillus subtilis, Enterococcus faecalis
Manually annotated by BRENDA team
Chernyshev, A.; Fleischmann, T.; Kohen, A.
Thymidyl biosynthesis enzymes as antibiotic targets
Appl. Microbiol. Biotechnol.
74
282-289
2007
Geobacillus stearothermophilus, Bacillus anthracis, Clostridium acidi-urici, Clostridium botulinum, Mycobacterium tuberculosis, Mycobacterium leprae, Rickettsia sp., Treponema palladium
Manually annotated by BRENDA team
Urbonavicius, J.; Skouloubris, S.; Myllykallio, H.; Grosjean, H.
Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria -evolutionary implications
Nucleic Acids Res.
33
3955-3964
2005
Bacillus subtilis (P39815), Bacillus subtilis
Manually annotated by BRENDA team
Cicmil, N.
Crystallization and preliminary X-ray crystallographic characterization of TrmFO, a folate-dependent tRNA methyltransferase from Thermotoga maritima
Acta Crystallogr. Sect. F
64
193-195
2008
Thermotoga maritima
Manually annotated by BRENDA team
Nishimasu, H.; Ishitani, R.; Yamashita, K.; Iwashita, C.; Hirata, A.; Hori, H.; Nureki, O.
Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase
Proc. Natl. Acad. Sci. USA
106
8180-8185
2009
Thermotoga maritima (Q9WZJ3)
Manually annotated by BRENDA team
Hamdane, D.; Guerineau, V.; Un, S.; Golinelli-Pimpaneau, B.
A catalytic intermediate and several flavin redox states stabilized by folate-dependent tRNA methyltransferase from Bacillus subtilis
Biochemistry
50
5208-5219
2011
Bacillus subtilis
Manually annotated by BRENDA team
Hamdane, D.; Argentini, M.; Cornu, D.; Myllykallio, H.; Skouloubris, S.; Hui-Bon-Hoa, G.; Golinelli-Pimpaneau, B.
Insights into folate/FAD-dependent tRNA methyltransferase mechanism: role of two highly conserved cysteines in catalysis
J. Biol. Chem.
286
36268-36280
2011
Bacillus subtilis
Manually annotated by BRENDA team
Hamdane, D.; Skouloubris, S.; Myllykallio, H.; Golinelli-Pimpaneau, B.
Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis
Protein Expr. Purif.
73
83-89
2010
Bacillus subtilis
Manually annotated by BRENDA team
Yamagami, R.; Yamashita, K.; Nishimasu, H.; Tomikawa, C.; Ochi, A.; Iwashita, C.; Hirata, A.; Ishitani, R.; Nureki, O.; Hori, H.
The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO)
J. Biol. Chem.
287
42480-42494
2012
Thermus thermophilus (Q5SID2), Thermus thermophilus, Thermus thermophilus DSM 579 (Q5SID2)
Manually annotated by BRENDA team
Yamagami, R.; Tomikawa, C.; Shigi, N.; Kazayama, A.; Asai, S.; Takuma, H.; Hirata, A.; Fourmy, D.; Asahara, H.; Watanabe, K.; Yoshizawa, S.; Hori, H.
Folate-/FAD-dependent tRNA methyltransferase from Thermus thermophilus regulates other modifications in tRNA at low temperatures
Genes Cells
21
740-754
2016
Thermus thermophilus (Q5SID2), Thermus thermophilus
Manually annotated by BRENDA team