Information on EC 2.1.1.295 - 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY hide
2.1.1.295
-
RECOMMENDED NAME
GeneOntology No.
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol = S-adenosyl-L-homocysteine + plastoquinol
show the reaction diagram
S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol
show the reaction diagram
S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol
show the reaction diagram
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Biosynthesis of secondary metabolites
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Metabolic pathways
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plastoquinol-9 biosynthesis I
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plastoquinol-9 biosynthesis II
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Ubiquinone and other terpenoid-quinone biosynthesis
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vitamin E biosynthesis (tocopherols)
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vitamin E biosynthesis (tocotrienols)
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vitamin E metabolism
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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C3-methyltransferase
Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols).
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene VTE3
UniProt
Manually annotated by BRENDA team
Arachis fastigiata
var. fastigiata and var. vulgaris, gene VTE3
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-
Manually annotated by BRENDA team
var. hypogaea and var. hirsuta, gene VTE3
UniProt
Manually annotated by BRENDA team
gene VTE3
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
malfunction
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an SLL0418 partial knockout mutant accumulates beta-tocopherol with no effect in the overall tocopherol content of the cell
metabolism
physiological function
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol
S-adenosyl-L-homocysteine + plastoquinol
show the reaction diagram
S-adenosyl-L-methionine + 2-methyl-6-phytyl-1,4-benzoquinol
S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytyl-1,4-benzoquinone
show the reaction diagram
S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol
S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol
show the reaction diagram
S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol
S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol
S-adenosyl-L-homocysteine + plastoquinol
show the reaction diagram
-
the enzyme is involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols)
-
-
?
S-adenosyl-L-methionine + 2-methyl-6-phytyl-1,4-benzoquinol
S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytyl-1,4-benzoquinone
show the reaction diagram
S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol
S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol
show the reaction diagram
-
the enzyme is involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols)
-
-
?
S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol
S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol
show the reaction diagram
-
the enzyme is involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols)
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
S-adenosyl-L-methionine
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8
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assay at
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
28
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assay at
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
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gene VTE3, cloning of full-length VTE3 cDNA (designated rVTE3-1 and -2) encoding the enzyme MPBQ MT, and of the full-length DNA of VTE3 (des­ignated gVTE3-1 and -2), DNA and amino acid sequence determination and analysis, sequence comparisons, and polymorphism analysis, phylogenetic analysis
gene VTE3, cloning, DNA and amino acid sequence determination and analysis, sequence comparisons, and polymorphism analysis, phylogenetic analysis
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
T94I
mutation alters tocopherol composition of leaves but has little impact on plastoquinone levels
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture