Information on EC 2.1.1.210 - demethylspheroidene O-methyltransferase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.1.1.210
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RECOMMENDED NAME
GeneOntology No.
demethylspheroidene O-methyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + demethylspheroidene = S-adenosyl-L-homocysteine + spheroidene
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
spheroidene and spheroidenone biosynthesis
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Carotenoid biosynthesis
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Metabolic pathways
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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase
In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene [1,2,3]. In Rubrivivax gelatinosus the enzyme also catalyses the methylation of demethylspirilloxanthin to spirilloxanthin and the methylation of 3,4-didehydrorhodopin to anhydrorhodovibrin [2].
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
physiological function
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the enzyme is involved in spheroidene biosynthesis pathway and spirilloxanthin biosynthesis pathway. Methylated carotenoids, such as spheroidene and spirilloxanthin, function as accessory pigments in the light-harvesting and reaction-center complexes of purple bacteria
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-D-methionine + demethylspheroidene
S-adenosyl-L-homocysteine + spheroidene
show the reaction diagram
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-
-
-
?
S-adenosyl-L-methionine + 1'-hydroxydemethylspheroidene
S-adenosyl-L-homocysteine + 1'-hydroxyspheroidene
show the reaction diagram
S-adenosyl-L-methionine + 1,1'-dihydroxy-3,4,3',4'-tetradehydrolycopene
S-adenosyl-L-homocysteine + 1,1'-dimethoxy-3,4,3',4'-tetradehydrolycopene
show the reaction diagram
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not involved in the carotenogenic pathway of Rhodobacter capsulatus
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?
S-adenosyl-L-methionine + 1,1'-dihydroxy-3,4-didehydrolycopene
S-adenosyl-L-homocysteine + 1,1'-dimethoxy-3,4-didehydrolycopene
show the reaction diagram
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not involved in the carotenogenic pathway of Rhodobacter capsulatus
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-
?
S-adenosyl-L-methionine + 1,1'-dihydroxylycopene
S-adenosyl-L-homocysteine + 1,1'-dimethoxylycopene
show the reaction diagram
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not involved in the carotenogenic pathway of Rhodobacter capsulatus
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-
?
S-adenosyl-L-methionine + 1,1'-dihydroxyneurosporene
S-adenosyl-L-homocysteine + 1-methoxy-1'-hydroxyneurosporene
show the reaction diagram
S-adenosyl-L-methionine + 1-hydroxy-3,4-didehydrolycopene
S-adenosyl-L-homocysteine + 1-methoxy-3,4-didehydrolycopene
show the reaction diagram
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not involved in the carotenogenic pathway of Rhodobacter capsulatus
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-
?
S-adenosyl-L-methionine + 1-hydroxylycopene
S-adenosyl-L-homocysteine + 1-methoxylycopene
show the reaction diagram
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not involved in the carotenogenic pathway of Rhodobacter capsulatus
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-
?
S-adenosyl-L-methionine + 1-hydroxyneurosporene
S-adenosyl-L-homocysteine + 1-methoxyneurosporene
show the reaction diagram
S-adenosyl-L-methionine + demethylspheroidene
S-adenosyl-L-homocysteine + spheroidene
show the reaction diagram
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-D-methionine + demethylspheroidene
S-adenosyl-L-homocysteine + spheroidene
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + 1'-hydroxydemethylspheroidene
S-adenosyl-L-homocysteine + 1'-hydroxyspheroidene
show the reaction diagram
-
the enzyme is involved in the biosynthesis of spheroidene and spirilloxanthin, essential components of the photosynthetic apparatus
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-
?
S-adenosyl-L-methionine + 1,1'-dihydroxyneurosporene
S-adenosyl-L-homocysteine + 1-methoxy-1'-hydroxyneurosporene
show the reaction diagram
-
the enzyme is involved in the biosynthesis of spheroidene and spirilloxanthin, essential components of the photosynthetic apparatus
-
-
?
S-adenosyl-L-methionine + 1-hydroxyneurosporene
S-adenosyl-L-homocysteine + 1-methoxyneurosporene
show the reaction diagram
-
the enzyme is involved in the biosynthesis of spheroidene and spirilloxanthin, essential components of the photosynthetic apparatus
-
-
?
S-adenosyl-L-methionine + demethylspheroidene
S-adenosyl-L-homocysteine + spheroidene
show the reaction diagram
additional information
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
S-adenosyl-L-methionine
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0266
1'-hydroxydemethylspheroidene
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pH 8.0, 28°C
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
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x * 43000, SDS-PAGE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli in an active form
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