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The expected taxonomic range for this enzyme is: Pseudomonas sp.
Synonyms
trimethylsulfonium-tetrahydrofolate methyltransferase,
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trimethylsulfonium-tetrahydrofolate methyltransferase
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trimethylsulfonium + tetrahydrofolate = dimethylsulfide + 5-methyltetrahydrofolate + H+
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methyl group transfer
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trimethylsulfonium:tetrahydrofolate N-methyltransferase
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trimethylsulfonium + tetrahydrofolate
dimethylsulfide + 5-methyltetrahydrofolate
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additional information
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S-adenosylmethionine and dimethyl-beta-propiothetin are not accepted as methyl donors
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2-mercaptoethanol
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inhibitory in excess
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2-mercaptoethanol
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reducing agent required for activity
ascorbate
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can replace 2-mercaptoethanol, best reducing agent for reaction assay
homocysteine
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can replace 2-mercaptoethanol
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5.8
Trimethylsulfonium
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atypical pseudomonad with two lateral, subpolar flagellae
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brenda
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100000
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sucrose density gradient centrifugation
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-20°C, 80% activity retained after 4 months
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Wagner, C.; Lusty, S.M.; Kung, H.; Rogers, N.L.
Preparation and properties of trimethylsulfonium-tetrahydrofolate methyltransferase
J. Biol. Chem.
242
1287-1293
1967
Pseudomonas sp.
brenda
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