Information on EC 2.1.1.149 - myricetin O-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)

The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
2.1.1.149
deleted, now covered by EC 2.1.1.267, flavonoid 3',5'-methyltransferase
RECOMMENDED NAME
GeneOntology No.
myricetin O-methyltransferase
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
-
phylogenic analysis suggests that the 3-OMT activity has probably evolved from an ancestral 3'/5' methyltransferase activity. Phylogenetic analysis revealing the level of relatedness of the ShMOMT3-encoded protein to a the ShMOMT1, ShMOMT2, SlMOMT1-, SlMOMT2-, and SlMOMT3-encoded proteins and other plant OMTs, overview
physiological function
-
ShMOMT3 is a flavonol 3-O-methyltransferase, it catalyzes the transfer of a methyl group to the C3 position hydroxyl group of myricetin and other structurally similar flavonols, i.e. C3-specificity
additional information
-
wild tomato species Solanum habrochaites accumulate the polymethylated flavonol aglycones, 3,7,3'-O-methyl myricetin, 3,7,3',5'-O-methyl myricetin, and 3,7,3',4',5'-O-methyl myricetin
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0005 - 0.0026
caffeoyl-coenzyme A
39173
0.000534 - 0.00276
luteolin
436
0.0009 - 2.74
myricetin
484
0.000949 - 0.00283
tricetin
2788