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IUBMB CommentsThe enzyme from Euglena gracilis methylates Met-65 of horse heart cytochrome c.
The expected taxonomic range for this enzyme is: Euglena gracilis
Synonyms
Methyltransferase, cytochrome c (methionine),
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Methyltransferase, cytochrome c (methionine)
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S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
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methyl group transfer
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S-adenosyl-L-methionine:[cytochrome c]-methionine S-methyltransferase
The enzyme from Euglena gracilis methylates Met-65 of horse heart cytochrome c.
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S-Adenosyl-L-methionine + [cytochrome c]-methionine
S-Adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
S-Adenosyl-L-methionine + [cytochrome c]-methionine
S-Adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
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various types of histones are not modified
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S-Adenosyl-L-methionine + [cytochrome c]-methionine
S-Adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine
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the methylation site is Met65
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S-Adenosyl-D-homocysteine
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S-adenosyl-L-homocysteine
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0.0166
S-adenosyl-L-methionine
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brenda
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-70°C, 50% loss of activity after 1 week
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Farooqui, J.Z.; Tuck, M.; Paik, W.K.
Purification and characterization of enzymes from Euglena gracilis that methylate methionine and arginine residues of cytochrome c
J. Biol. Chem.
260
537-545
1985
Euglena gracilis
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