Reference on EC 1.4.3.3 - D-amino-acid oxidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bright, H.J.; Porter, D.J.T.
Flavoprotein oxidases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
12
421-505
1975
Sus scrofa
-
Sacchi, S.; Lorenzi, S.; Molla, G.; Pilone, M.S.; Rossetti, C.; Pollegioni, L.
Engineering the substrate specificity of D-amino-acid oxidase
J. Biol. Chem.
277
27510-27516
2002
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Dixon, M.; Kleppe, K.
D-Amino acid oxidase I. Dissociation and recombination of the holoenzyme
Biochim. Biophys. Acta
96
357-367
1965
Sus scrofa
Dixon, M.; Kleppe, K.
D-Amino acid oxidase II. specificity, competitive inhibition and reaction sequence
Biochim. Biophys. Acta
96
368-382
1965
Sus scrofa
-
Dixon, M.; Kleppe, K.
D-Amino acid oxidase II. Effect of pH
Biochim. Biophys. Acta
96
383-389
1965
Sus scrofa
Tosa, T.; Sano, R.; Chibata, I.
Immobilized D-amino acid oxidase. Preparation, some enzymatic properties, and potential uses
Agric. Biol. Chem.
38
1529-1534
1974
Sus scrofa
-
Harbron, S.; Fisher, M.; Rabin, B.R.
Large scale preparation and purification of apo-D-aminoacid oxidase for use in novel amplification assays
Biotechnol. Tech.
6
55-60
1992
Sus scrofa
-
Simonetta, M.P.; Pollegioni, L.; Casalin, P.; Curti, B.; Ronchi, S.
Properties of D-amino-acid oxidase from Rhodotorula gracilis
Eur. J. Biochem.
180
199-204
1989
Rhodotorula toruloides
Pollegioni, L.; Falbo, A.; Pilone, M.S.
Specificity and kinetics of Rhodotorula gracilis D-amino acid oxidase
Biochim. Biophys. Acta
1120
11-16
1992
Rhodotorula toruloides
Yoshizawa, M.; Ueda, M.; Mozaffar, S.; Tanaka, A.
Some properties of peroxisome-associated D-amino acid oxidase from Candida tropicalis
Agric. Biol. Chem.
50
2637-2638
1986
Candida tropicalis
-
Watanabe, F.; Fukui, K.; Momoi, K.; Miyake, Y.
Expression of normal and abnormal porcine kidney D-amino acid oxidase in Escherichia coli: purification and characterization of the enzymes
Biochem. Biophys. Res. Commun.
165
1422-1427
1989
Sus scrofa
Tarelli, G.T.; Vanoni, M.A.; Negri, A.; Curti, B.
Characterization of a fully active N-terminal 37-kDa polypeptide obtained by limited tryptic cleavage of pig kidney D-amino acid oxidase
J. Biol. Chem.
265
21242-21246
1990
Sus scrofa
Yagi, K.
D-Amino acid oxidase and its complexes (hog kidney)
Methods Enzymol.
17B
608-622
1971
Sus scrofa
-
Berg, C.P.; Rodden, F.A.
Purification of D-amino oxidase from Trigonopsis variabilis
Anal. Biochem.
71
214-222
1976
Trigonopsis variabilis
Rosenfeld, M.G.; Leiter, E.H.
Isolation and characterization of a mitochondrial D-amino acid oxidase from Neurospora crassa
Can. J. Biochem.
55
66-74
1977
Neurospora crassa
Pistorius, E.K.; Voss, H.
A D-amino acid oxidase from Chlorella vulgaris
Biochim. Biophys. Acta
481
395-406
1977
Chlorella vulgaris
Parkin, K.; Hultin, H.O.
Immobilization and characterization of D-amino acid oxidase
Biotechnol. Bioeng.
21
939-953
1979
Sus scrofa
Hamilton, G.A.; Buckthal, D.J.
The inhibition of mammalian D-amino acid oxidase by metabolites and drugs. Inferences concerning physiological function
Bioorg. Chem.
11
350-370
1982
Sus scrofa
-
Simonetta, M.P.; Vanoni, M.A.; Curti, B.
D-Amino acid oxidase activity in the yeast Rhodotorula gracilis
FEMS Microbiol. Lett.
15
27-31
1982
Rhodotorula toruloides
-
Carrera, G.; Pasta, P.; Curti, B.
Renaturation studies of free and immobilized D-amino-acid oxidase
Biochim. Biophys. Acta
745
181-188
1983
Sus scrofa
Szwajcer, E.; Mosbach, K.
Isolation and partial characterization of a D-amino acid oxidase active against cephalosporin. c from the yeast Trigonopsis variabilis
Biotechnol. Lett.
7
1-7
1985
Trigonopsis variabilis
-
Kubicek-Pranz, E.M.; Rhr, M.
D-amino acid oxidase from the yeast Trigonopsis variabilis
J. Appl. Biochem.
7
104-113
1985
Trigonopsis variabilis
Schraeder, T.; Andreesen, J.R.
Properties and chemical modification of D-amino acid oxidase from Trigonopsis variabilis
Arch. Microbiol.
165
41-47
1996
Trigonopsis variabilis
-
Bergmeyer, H.U.
D-Aminosure-Oxydase
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
1
460-461
1974
Sus scrofa
-
Leonil, J.; Langrene, S.; Sicsic, S.; Le Goffic, F.
Purification of D-amino acid oxidase apoenzyme by affinity chromatography on Cibacron Blue Sepharose
J. Chromatogr.
347
316-319
1985
Sus scrofa
Tu, S.C.; Edelstein, S.J.; McCormick, D.B.
A modified purification method and properties of pure porcine D-amino acid oxidase
Arch. Biochem. Biophys.
159
889-896
1973
Sus scrofa
-
Simonetta, M.P.; Vanoni, M.A.; Casalin, P.
Purification and properties of D-amino-acid oxidase, an inducible flavoenzyme from Rhodotorula gracilis
Biochim. Biophys. Acta
914
136-142
1987
Rhodotorula toruloides
-
Yurimoto, H.; Hasegawa, T.; Sakai, Y.; Kato, N.
Characterization and high-level production of D-amino acid oxidase in Candida boidinii
Biosci. Biotechnol. Biochem.
65
627-633
2001
[Candida] boidinii
Setoyama, C.; Nishina,Y.; Tamaoki, H.; Mizutani, H.; Miyahara, I.; Hirotsu, K.; Shiga, K.; Miura, R.
Effects of hydrogen bond in association with flavin and substrate in flavoenzyme D-amino acid oxidase. The catalytic and structural roles of gly313 and thr317
J. Biochem.
131
59-69
2002
Sus scrofa
Molla, G.; Porrini, D.; Job, V.; Motteran, L.; Vegezzi, C.; Campaner, S.; Pilone, M.S.; Pollegioni, L.
Role of arginine 285 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study
J. Biol. Chem.
275
24715-24721
2000
Rhodotorula toruloides
Ju, S.S.; Lin, L.L.; Wang, W.C.; Hsu, W.H.
A conserved aspartate is essential for FAD binding and catalysis in the D-amino acid oxidase from Trigonopsis variabilis
FEBS Lett.
436
119-122
1998
Trigonopsis variabilis
Pollegioni, L.; Porrini, D.; Molla, G.; Pilone, M.S.
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis
Eur. J. Biochem.
267
6624-6632
2000
Rhodotorula toruloides, Trigonopsis variabilis
Pollegioni, L.; Langkau, B.; Tischer, W.; Ghisla, S.; Pilone, M.S.
Kinetic mechanism of D-amino acid oxidases from Rhodotorula gracilis and Trigonopsis variabilis
J. Biol. Chem.
268
13850-13857
1993
Rhodotorula toruloides, Trigonopsis variabilis
Raibekas, A.A.; Fukui, K.; Massey, V.
Design and properties of human D-amino acid oxidase with covalently attached flavin
Proc. Natl. Acad. Sci. USA
97
3089-3093
2000
Homo sapiens
Pollegioni, L.; Fukui, K.; Massey, V.
Studies on the kinetic mechanism of pig kidney D-amino acid oxidase by site-directed mutagenesis of tyrosine 224 and tyrosine 228
J. Biol. Chem.
269
31666-31673
1994
Sus scrofa
Pollegioni, L.; Ceciliani, F.; Curti, B.; Ronchi, S.; Pilone, M.S.
Studies on the structural and functional aspects of Rhodotorula gracilis D-amino acid oxidase by limited trypsinolysis
Biochem. J.
310
577-583
1995
Rhodotorula toruloides
Pilone, M.S.
D-Amino acid oxidase: new findings
Cell. Mol. Life Sci.
57
1732-1747
2000
Homo sapiens, Rhodotorula toruloides, Sus scrofa, Trigonopsis variabilis
Vikartovska-Welwardova, A.; Michalkova, E.; Gemeiner, P.; Welward, L.
Stabilization of D-amino-acid oxidase from Trigonopsis variabilis by manganese dioxide
Folia Microbiol. (Praha)
44
380-384
1999
Trigonopsis variabilis
Parveen, Z.; Large, A.; Grewal, N.; Lata, N.; Cancio, I.; Cajaraville, M.P.; Perry, C.J.; Connock, M.J.
D-Aspartate oxidase and D-amino acid oxidase are localized in the peroxisomes of terrestrial gastropods
Eur. J. Cell Biol.
80
651-660
2001
Achatina achatina, Arion ater, Mus musculus
Moreno, J.A.; Montes, F.J.; Catalan, J.; Galan, M.A.
Inhibition of D-amino acid oxidase by alpha-keto acids analogs of amino acids
Enzyme Microb. Technol.
18
379-382
1996
Sus scrofa
Pollegioni, L.; Buto, S.; Tischer, W.; Ghisla, S.; Pilone, M.S.
Characterization of D-amino acid oxidase from Trigonopsis variabilis
Biochem. Mol. Biol. Int.
31
709-717
1993
Trigonopsis variabilis
Bakke, M.; Kajiyama, N.
Improvement in thermal stability and substrate binding of pig kidney D-amino acid oxidase by chemical modification
Appl. Biochem. Biotechnol.
112
123-131
2004
Sus scrofa
Sarower, M.G.; Okada, S.; Abe, H.
Molecular characterization of D-amino acid oxidase from common carp Cyprinus carpio and its induction with exogenous free D-alanine
Arch. Biochem. Biophys.
420
121-129
2003
Cyprinus carpio (Q6TGN2), Cyprinus carpio
Tishkov, V.I.; Khoronenkova, S.V.
D-Amino acid oxidase: structure, catalytic mechanism, and practical application
Biochemistry
70
40-54
2005
Candida parapsilosis, Fusarium oxysporum, Rhodotorula toruloides, Sus scrofa, Trigonopsis variabilis, Acrostalagmus luteoalbus, [Candida] boidinii (Q9HGY3)
Boselli, A.; Piubelli, L.; Molla, G.; Sacchi, S.; Pilone, M.S.; Ghisla, S.; Pollegioni, L.
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335
Biochim. Biophys. Acta
1702
19-32
2004
Rhodotorula toruloides
Betancor, L.; Hidalgo, A.; Fernandez-Lorente, G.; Mateo, C.; Rodriguez, V.; Fuentes, M.; Lopez-Gallego, F.; Fernandez-Lafuente, R.; Guisan, J.M.
Use of physicochemical tools to determine the choice of optimal enzyme: stabilization of D-amino acid oxidase
Biotechnol. Prog.
19
784-788
2003
Rhodotorula toruloides, Trigonopsis variabilis
Pollegioni, L.; Caldinelli, L.; Molla, G.; Sacchi, S.; Pilone, M.S.
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: a comparison between proteins from different sources
Biotechnol. Prog.
20
467-473
2004
Rhodotorula toruloides, Sus scrofa, Trigonopsis variabilis
Sarower, M.G.; Okada, S.; Abe, H.
Catalytic and structural characteristics of carp hepatopancreas D-amino acid oxidase expressed in Escherichia coli
Comp. Biochem. Physiol. B
140
417-425
2005
Cyprinus carpio (Q6TGN2), Cyprinus carpio
Boselli, A.; Sacchi, S.; Job, V.; Pilone, M.S.; Pollegioni, L.
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study
Eur. J. Biochem.
269
4762-4771
2002
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Piubelli, L.; Caldinelli, L.; Molla, G.; Pilone, M.S.; Pollegioni, L.
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach
FEBS Lett.
526
43-48
2002
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Sarower, M.G.; Matsui, T.; Abe, H.
Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues
J. Exp. Zool. A
295
151-159
2003
Chaunax fimbriatus, Cololabis saira, Cyprinus carpio, Evynnis tumifrons, Lateolabrax japonicus, Oncorhynchus keta, Oncorhynchus masou, Oncorhynchus mykiss, Pagrus major, Paralichthys olivaceus, Plecoglossus altivelis, Pseudopleuronectes yokohamae, Sardinops melanostictus, Scomber japonicus, Thamnaconus tessellatus, Trachurus japonicus, Verasper variegatus
Pollegioni, L.; Diederichs, K.; Molla, G.; Umhau, S.; Welte, W.; Ghisla, S.; Pilone, M.S.
Yeast D-amino acid oxidase: structural basis of its catalytic properties
J. Mol. Biol.
324
535-546
2002
Rhodotorula toruloides
Pollegioni, L.; Iametti, S.; Fessas, D.; Caldinelli, L.; Piubelli, L.; Barbiroli, A.; Pilone, M.S.; Bonomi, F.
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase
Protein Sci.
12
1018-1029
2003
Rhodotorula toruloides
Sarower, M.G.; Matsui, T.; Abe, H.
Distribution and substrate specificity of D-amino acid and D-aspartate oxidases in marine invertebrates
Science Asia
30
335-340
2004
Turbo cornutus, Meretrix lusoria, Mytilus galloprovincialis, Octopus vulgaris, Mizuhopecten yessoensis, Penaeus japonicus, Anadara broughtonii, Todarodes pacificus, Procambarus clarkii, Tresus keenae
-
Molla, G.; Motteran, L.; Piubelli, L.; Pilone, M.S.; Pollegioni, L.
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis
Yeast
20
1061-1069
2003
Rhodotorula toruloides
Verweij, J.; Vroom, E.D.
Industrial transformation of penicillins and cephalosporins
Rec. Trav. Chim. Pays-Bas
112
66-81
1993
Trigonopsis variabilis
-
Dememes, D.; Mothet, J.P.; Nicolas, M.T.
Cellular distribution of d-serine, serine racemase and d-amino acid oxidase in the rat vestibular sensory epithelia
Neuroscience
137
991-997
2006
Rattus norvegicus
Slavica, A.; Dib, I.; Nidetzky, B.
Single-site oxidation, cysteine 108 to cysteine sulfinic acid, in D-amino acid oxidase from Trigonopsis variabilis and its structural and functional consequences
Appl. Environ. Microbiol.
71
8061-8068
2005
Trigonopsis variabilis (Q6R4Q9), Trigonopsis variabilis (Q99042), Trigonopsis variabilis
Dib, I.; Stanzer, D.; Nidetzky, B.
Trigonopsis variabilis D-amino aacid oxidase: control of protein quality and opportunities for biocatalysis through production in Escherichia coli
Appl. Environ. Microbiol.
73
331-333
2007
Trigonopsis variabilis
Zheng, H.; Wang, X.; Chen, J.; Zhu, K.; Zhao, Y.; Yang, Y.; Yang, S.; Jiang, W.
Expression, purification, and immobilization of His-tagged D-amino acid oxidase of Trigonopsis variabilis in Pichia pastoris
Appl. Microbiol. Biotechnol.
70
683-689
2006
Trigonopsis variabilis
Hamase, K.; Konno, R.; Morikawa, A.; Zaitsu, K.
Sensitive determination of D-amino acids in mammals and the effect of D-amino-acid oxidase activity on their amounts
Biol. Pharm. Bull.
28
1578-1584
2005
Mus musculus
Bakke, M.; Setoyama, C.; Miura, R.; Kajiyama, N.
Thermostabilization of porcine kidney D-amino acid oxidase by a single amino acid substitution
Biotechnol. Bioeng.
93
1023-1027
2006
Sus scrofa
Dib, I.; Slavica, A.; Riethorst, W.; Nidetzky, B.
Thermal inactivation of D-amino acid oxidase from Trigonopsis variabilis occurs via three parallel paths of irreversible denaturation
Biotechnol. Bioeng.
94
645-654
2006
Trigonopsis variabilis
Maekawa, M.; Okamura, T.; Kasai, N.; Hori, Y.; Summer, K.H.; Konno, R.
D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity
Chem. Res. Toxicol.
18
1678-1682
2005
Rattus norvegicus
Wu, M.; Zhou, X.J.; Konno, R.; Wang, Y.X.
D-dopa is unidirectionally converted to L-dopa by D-amino acid oxidase, followed by dopa transaminase
Clin. Exp. Pharmacol. Physiol.
33
1042-1046
2006
Rattus norvegicus
Caldinelli, L.; Molla, G.; Pilone, M.S.; Pollegioni, L.
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis
FEBS J.
273
504-512
2006
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Molla, G.; Sacchi, S.; Bernasconi, M.; Pilone, M.S.; Fukui, K.; Polegioni, L.
Characterization of human D-amino acid oxidase
FEBS Lett.
580
2358-2364
2006
Homo sapiens
Park, H.K.; Shishido, Y.; Ichise-Shishido, S.; Kawazoe, T.; Ono, K.; Iwana, S.; Tomita, Y.; Yorita, K.; Sakai, T.; Fukui, K.
Potential role for astroglial D-amino acid oxidase in extracellular D-serine metabolism and cytotoxicity
J. Biochem.
139
295-304
2006
Mus musculus
Setoyama, C.; Nishina, Y.; Mizutani, H.; Miyahara, I.; Hirotsu, K.; Kamiya, N.; Shiga, K.; Miura, R.
Engineering the substrate specificity of porcine kidney D-amino acid oxidase by mutagenesis of the active-site lid
J. Biochem.
139
873-879
2006
Sus scrofa
Lutz-Wahl, S.; Trost, E.M.; Wagner, B.; Manns, A.; Fischer, L.
Performance of D-amino acid oxidase in presence of ionic liquids
J. Biotechnol.
124
163-171
2006
Trigonopsis variabilis, Trigonopsis variabilis CBS 4095
Trampitsch, C.; Slavica, A.; Riethorst, W.; Nidetzky, B.
Reaction of Trigonopsis variabilis D-amino acid oxidase with 2,6-dichloroindophenol: kinetic characterization and development of an oxygen-independent assay of the enzyme activity
J. Mol. Catal. B
32
271-278
2005
Trigonopsis variabilis
-
Kawazoe, T.; Tsuge, H.; Pilone, M.S.; Fukui, K.
Crystal structure of human D-amino acid oxidase: context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring
Protein Sci.
15
2708-2717
2006
Homo sapiens
Tanaka, H.; Yamamoto, A.; Ishida, T.; Horiike, K.
Simultaneous measurement of D-serine dehydratase and d-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography
Anal. Biochem.
362
83-88
2007
Gallus gallus, Rattus norvegicus
Verrall, L.; Walker, M.; Rawlings, N.; Benzel, I.; Kew, J.N.; Harrison, P.J.; Burnet, P.W.
D-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia
Eur. J. Neurosci.
26
1657-1669
2007
Homo sapiens
Hashimoto, A.; Yoshikawa, M.; Andoh, H.; Yano, H.; Matsumoto, H.; Kawaguchi, M.; Oka, T.; Kobayashi, H.
Effects of MK-801 on the expression of serine racemase and D-amino acid oxidase mRNAs and on the D-serine levels in rat brain
Eur. J. Pharmacol.
555
17-22
2007
Rattus norvegicus
Corvin, A.; McGhee, K.A.; Murphy, K.; Donohoe, G.; Nangle, J.M.; Schwaiger, S.; Kenny, N.; Clarke, S.; Meagher, D.; Quinn, J.; Scully, P.; Baldwin, P.; Browne, D.; Walsh, C.; Waddington, J.L.; Morris, D.W.; Gill, M.
Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample
Am. J. Med. Genet. B Neuropsychiatr. Genet.
144B
949-953
2007
Homo sapiens
Khoronenkova, S.V.; Tishkov, V.I.
High-throughput screening assay for D-amino acid oxidase
Anal. Biochem.
374
405-410
2008
Trigonopsis variabilis
Pernot, P.; Mothet, J.P.; Schuvailo, O.; Soldatkin, A.; Pollegioni, L.; Pilone, M.; Adeline, M.T.; Cespuglio, R.; Marinesco, S.
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system
Anal. Chem.
80
1589-1597
2008
Rhodotorula toruloides, Sus scrofa
Halvey, P.J.; Hansen, J.M.; Johnson, J.M.; Go, Y.M.; Samali, A.; Jones, D.P.
Selective oxidative stress in cell nuclei by nuclear-targeted D-amino acid oxidase
Antioxid. Redox Signal.
9
807-816
2007
Homo sapiens
Tan, Q.; Song, Q.; Zhang, Y.; Wei, D.
Characterization and application of D-amino acid oxidase and catalase within permeabilized Pichia pastoris cells in bioconversions
Appl. Biochem. Biotechnol.
136
279-289
2007
Komagataella pastoris
Geueke, B.; Weckbecker, A.; Hummel, W.
Overproduction and characterization of a recombinant D-amino acid oxidase from Arthrobacter protophormiae
Appl. Microbiol. Biotechnol.
74
1240-1247
2007
Glutamicibacter protophormiae (Q7X2D3), Glutamicibacter protophormiae
Pollegioni, L.; Molla, G.; Sacchi, S.; Rosini, E.; Verga, R.; Pilone, M.S.
Properties and applications of microbial D-amino acid oxidases: current state and perspectives
Appl. Microbiol. Biotechnol.
78
1-16
2008
Fusarium solani (P24552), Rhodotorula toruloides (P80324), Rubrobacter xylanophilus (Q1AYM8), Glutamicibacter protophormiae (Q7X2D3), Trigonopsis variabilis (Q99042), [Candida] boidinii (Q9HGY3), Mycobacterium leprae (Q9RIA4)
Kawazoe, T.; Tsuge, H.; Imagawa, T.; Aki, K.; Kuramitsu, S.; Fukui, K.
Structural basis of D-DOPA oxidation by D-amino acid oxidase: altersodiumtive pathway for dopamine biosynthesis
Biochem. Biophys. Res. Commun.
355
385-391
2007
Homo sapiens (P14920), Homo sapiens
Nidetzky, B.
Stability and stabilization of D-amino acid oxidase from the yeast Trigonopsis variabilis
Biochem. Soc. Trans.
35
1588-1592
2007
Trigonopsis variabilis
Arroyo, M.; Menendez, M.; Garcia, J.L.; Campillo, N.; Hormigo, D.; De la Mata, I.; Castillon, M.P.; Acebal, C.
The role of cofactor binding in tryptophan accessibility and conformational stability of His-tagged D-amino acid oxidase from Trigonopsis variabilis
Biochim. Biophys. Acta
1774
556-565
2007
Trigonopsis variabilis (Q99042), Trigonopsis variabilis
Boselli, A.; Piubelli, L.; Molla, G.; Pilone, M.S.; Pollegioni, L.; Sacchi, S.
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity
Biochimie
89
360-368
2007
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Sparey, T.; Abeywickrema, P.; Almond, S.; Brandon, N.; Byrne, N.; Campbell, A.; Hutson, P.H.; Jacobson, M.; Jones, B.; Munshi, S.; Pascarella, D.; Pike, A.; Prasad, G.S.; Sachs, N.; Sakatis, M.; Sardana, V.; Venkatraman, S.; Young, M.B.
The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors
Bioorg. Med. Chem. Lett.
18
3386-3391
2008
Homo sapiens (P14920)
Nahalka, J.; Dib, I.; Nidetzky, B.
Encapsulation of Trigonopsis variabilis D-amino acid oxidase and fast comparison of the operational stabilities of free and immobilized preparations of the enzyme
Biotechnol. Bioeng.
99
251-260
2008
Trigonopsis variabilis
Kim, S.; Kim, N.; Shin, C.; Kim, C.
Optimization of culture condition for the production of D-amino acid oxidase in a recombinant Escherichia coli
Biotechnol. Bioprocess Eng.
13
144-149
2008
Trigonopsis variabilis, Trigonopsis variabilis CBS 4095
-
Wang, S.J.; Yu, C.Y.; Lee, C.K.; Chern, M.K.; Kuan, I.C.
Subunit fusion of two yeast D-amino acid oxidases enhances their thermostability and resistance to H2O2
Biotechnol. Lett.
30
1415-1422
2008
Rhodotorula toruloides, Trigonopsis variabilis
Wang, S.J.; Yu, C.Y.; Kuan, I.C.
Stabilization of native and double D-amino acid oxidases from Rhodosporidium toruloides and Trigonopsis variabilis by immobilization on streptavidin-coated magnetic beads
Biotechnol. Lett.
30
1973-1981
2008
Rhodotorula toruloides, Trigonopsis variabilis
Pollegioni, L.; Piubelli, L.; Sacchi, S.; Pilone, M.S.; Molla, G.
Physiological functions of D-amino acid oxidases: from yeast to humans
Cell. Mol. Life Sci.
64
1373-1394
2007
Chlorella vulgaris, Rattus norvegicus (O35078), Sus scrofa (P00371), Homo sapiens (P14920), Homo sapiens, Mus musculus (P18894), Rhodotorula toruloides (P80324), Cyprinus carpio (Q6TGN2), Trigonopsis variabilis (Q99042), [Candida] boidinii (Q9HGY3)
Kawazoe, T.; Park, H.K.; Iwana, S.; Tsuge, H.; Fukui, K.
Human D-amino acid oxidase: an update and review
Chem. Rec.
7
305-315
2007
Homo sapiens
Pollegioni, L.; Sacchi, S.; Caldinelli, L.; Boselli, A.; Pilone, M.S.; Piubelli, L.; Molla, G.
Engineering the properties of D-amino acid oxidases by a rational and a directed evolution approach
Curr. Protein Pept. Sci.
8
600-618
2007
Sus scrofa (P00371), Sus scrofa, Homo sapiens (P14920), Homo sapiens, Rhodotorula toruloides (P80324), Trigonopsis variabilis (Q99042)
Hashimoto, A.; Konno, R.; Yano, H.; Yoshikawa, M.; Tamaki, R.; Matsumoto, H.; Kobayashi, H.
Mice lacking D-amino acid oxidase activity exhibit marked reduction of methamphetamine-induced stereotypy
Eur. J. Pharmacol.
586
221-225
2008
Mus musculus
Adage, T.; Trillat, A.C.; Quattropani, A.; Perrin, D.; Cavarec, L.; Shaw, J.; Guerassimenko, O.; Giachetti, C.; Greco, B.; Chumakov, I.; Halazy, S.; Roach, A.; Zaratin, P.
In vitro and in vivo pharmacological profile of AS057278, a selective D-amino acid oxidase inhibitor with potential anti-psychotic properties
Eur. Neuropsychopharmacol.
18
200-214
2008
Homo sapiens (P14920), Homo sapiens, Rattus norvegicus
Chen, Y.; Chen, W.; Wang, Y.; Huang, M.; Chern, M.
Spatiotemporal expression of zebrafish D-amino acid oxidase during early embryogenesis
Fish Physiol. Biochem.
33
73-80
2007
Danio rerio (Q6NY97)
-
Fang, J.; Deng, D.; Nakamura, H.; Akuta, T.; Qin, H.; Iyer, A.K.; Greish, K.; Maeda, H.
Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase
Int. J. Cancer
122
1135-1144
2008
Sus scrofa
Sacchi, S.; Bernasconi, M.; Martineau, M.; Mothet, J.P.; Ruzzene, M.; Pilone, M.S.; Pollegioni, L.; Molla, G.
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: Effect on schizophrenia susceptibility
J. Biol. Chem.
283
22244-22256
2008
Homo sapiens, Sus scrofa
Kuan, I.; Liao, R.; Hsieh, H.; Chen, K.; Yu, C.
Properties of Rhodotorula gracilis D-amino acid oxidase immobilized on magnetic beads through His-tag
J. Biosci. Bioeng.
105
110-115
2008
Rhodotorula toruloides
Rosini, E.; Molla, G.; Rossetti, C.; Pilone, M.S.; Pollegioni, L.; Sacchi, S.
A biosensor for all D-amino acids using evolved D-amino acid oxidase
J. Biotechnol.
135
377-384
2008
Rhodotorula toruloides
Iwana, S.; Kawazoe, T.; Park, H.K.; Tsuchiya, K.; Ono, K.; Yorita, K.; Sakai, T.; Kusumi, T.; Fukui, K.
Chlorpromazine oligomer is a potentially active substance that inhibits human D-amino acid oxidase, product of a susceptibility gene for schizophrenia
J. Enzyme Inhib. Med. Chem.
23
901-911
2008
Homo sapiens
Ferraris, D.; Duvall, B.; Ko, Y.S.; Thomas, A.G.; Rojas, C.; Majer, P.; Hashimoto, K.; Tsukamoto, T.
Synthesis and biological evaluation of D-amino acid oxidase inhibitors
J. Med. Chem.
51
3357-3359
2008
Rattus norvegicus
Caligiuri, A.; DArrigo, P.; Rosini, E.; Pedrocchi-Fantoni, G.; Tessaro, D.; Molla, G.; Servi, S.; Pollegioni, L.
Activity of yeast D-amino acid oxidase on aromatic unnatural amino acids
J. Mol. Catal. B
50
93-98
2008
Rhodotorula toruloides (P80324)
-
Yoshikawa, M.; Shinomiya, T.; Takayasu, N.; Tsukamoto, H.; Kawaguchi, M.; Kobayashi, H.; Oka, T.; Hashimoto, A.
Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase
J. Pharmacol. Sci.
107
270-276
2008
Rattus norvegicus (O35078)
Corvin, A.; Donohoe, G.; McGhee, K.; Murphy, K.; Kenny, N.; Schwaiger, S.; Nangle, J.M.; Morris, D.; Gill, M.
D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia
Neurosci. Lett.
426
97-100
2007
Homo sapiens
Madeira, C.; Freitas, M.E.; Vargas-Lopes, C.; Wolosker, H.; Panizzutti, R.
Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia
Schizophr. Res.
101
76-83
2008
Homo sapiens
Konno, R.; Okamura, T.; Kasai, N.; Summer, K.H.; Niwa, A.
Mutant rat strain lacking D-amino-acid oxidase
Amino Acids
37
367-375
2009
Rattus norvegicus
Mora, M.F.; Giacomelli, C.E.; Garcia, C.D.
Interaction of D-amino acid oxidase with carbon nanotubes: implications in the design of biosensors
Anal. Chem.
81
1016-1022
2009
Sus scrofa
Liu, Y.; Li, Q.; Zhu, H.; Yang, J.
High soluble expression of D-amino acid oxidase in Escherichia coli regulated by a native promoter
Appl. Biochem. Biotechnol.
158
313-322
2008
Trigonopsis variabilis
Williams, M.
Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges
Biochem. Pharmacol.
78
1360-1365
2009
Homo sapiens, Rattus norvegicus
Khoronenkova, S.V.; Tishkov, V.I.
D-amino acid oxidase: physiological role and applications
Biochemistry (Moscow)
73
1511-1518
2008
Homo sapiens, Sus scrofa, Rhodotorula toruloides (P80324), Trigonopsis variabilis (Q99042)
Gholizadeh, A.; Kohnehrouz, B.B.
Molecular cloning and expression in Escherichia coli of an active fused Zea mays L. D-amino acid oxidase
Biochemistry (Moscow)
74
137-144
2009
Zea mays (A0PFJ3), Zea mays
Hashimoto, K.; Fujita, Y.; Horio, M.; Kunitachi, S.; Iyo, M.; Ferraris, D.; Tsukamoto, T.
Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine
Biol. Psychiatry
65
1103-1106
2009
Homo sapiens, Mus musculus
Kim, S.J.; Park, H.W.; Shin, C.H.; Kim, C.W.
Establishment of a cryopreservation method for the industrial use of D-amino acid oxidase-overexpressing Escherichia coli
Biosci. Biotechnol. Biochem.
73
299-303
2009
Trigonopsis variabilis, Trigonopsis variabilis CBS 4095
Hsieh, H.C.; Kuan, I.C.; Lee, S.L.; Tien, G.Y.; Wang, Y.J.; Yu, C.Y.
Stabilization of D-amino acid oxidase from Rhodosporidium toruloides by immobilization onto magnetic nanoparticles
Biotechnol. Lett.
31
557-563
2009
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Dib, I.; Nidetzky, B.
The stabilizing effects of immobilization in D-amino acid oxidase from Trigonopsis variabilis
BMC Biotechnol.
8
72
2008
Trigonopsis variabilis
Nguyen, L.P.; Hsu, E.L.; Chowdhury, G.; Dostalek, M.; Guengerich, F.P.; Bradfield, C.A.
D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan
Chem. Res. Toxicol.
22
1897-1904
2009
Homo sapiens, Sus scrofa (P00371)
Rosini, E.; Pollegioni, L.; Ghisla, S.; Orru, R.; Molla, G.
Optimization of D-amino acid oxidase for low substrate concentrations - towards a cancer enzyme therapy
FEBS J.
276
4921-4932
2009
Rhodotorula toruloides (P80324)
Labrie, V.; Wang, W.; Barger, S.W.; Baker, G.B.; Roder, J.C.
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice
Genes Brain Behav.
9
11-25
2009
Mus musculus (P18894)
Miyoshi, Y.; Hamase, K.; Tojo, Y.; Mita, M.; Konno, R.; Zaitsu, K.
Determination of D-serine and D-alanine in the tissues and physiological fluids of mice with various D-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection
J. Chromatogr. B
877
2506-2512
2009
Mus musculus (P18894)
Duplantier, A.J.; Becker, S.L.; Bohanon, M.J.; Borzilleri, K.A.; Chrunyk, B.A.; Downs, J.T.; Hu, L.Y.; El-Kattan, A.; James, L.C.; Liu, S.; Lu, J.; Maklad, N.; Mansour, M.N.; Mente, S.; Piotrowski, M.A.; Sakya, S.M.; Sheehan, S.; Steyn, S.J.; Strick, C.A.; Williams, V.A.; Zhang, L.
Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors
J. Med. Chem.
52
3576-3585
2009
Rattus norvegicus, Homo sapiens (P14920), Homo sapiens
Ono, K.; Shishido, Y.; Park, H.K.; Kawazoe, T.; Iwana, S.; Chung, S.P.; Abou El-Magd, R.M.; Yorita, K.; Okano, M.; Watanabe, T.; Sano, N.; Bando, Y.; Arima, K.; Sakai, T.; Fukui, K.
Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization study of the expression in human and rat brain
J. Neural Transm.
116
1335-1347
2009
Homo sapiens, Rattus norvegicus (O35078)
Habl, G.; Zink, M.; Petroianu, G.; Bauer, M.; Schneider-Axmann, T.; von Wilmsdorff, M.; Falkai, P.; Henn, F.A.; Schmitt, A.
Increased D-amino acid oxidase expression in the bilateral hippocampal CA4 of schizophrenic patients: a post-mortem study
J. Neural Transm.
116
1657-1665
2009
Homo sapiens
Smith, S.M.; Uslaner, J.M.; Yao, L.; Mullins, C.M.; Surles, N.O.; Huszar, S.L.; McNaughton, C.H.; Pascarella, D.M.; Kandebo, M.; Hinchliffe, R.M.; Sparey, T.; Brandon, N.J.; Jones, B.; Venkatraman, S.; Young, M.B.; Sachs, N.; Jacobson, M.A.; Hutson, P.H.
The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine
J. Pharmacol. Exp. Ther.
328
921-930
2009
Homo sapiens, Rattus norvegicus
Zhao, W.J.; Gao, Z.Y.; Wei, H.; Nie, H.Z.; Zhao, Q.; Zhou, X.J.; Wang, Y.X.
Spinal D-amino acid oxidase contributes to neuropathic pain in rats
J. Pharmacol. Exp. Ther.
332
248-254
2009
Rattus norvegicus
Abou El-Magd, R.; Park, H.; Kawazoe, T.; Iwana, S.; Ono, K.; Chung, S.; Miyano, M.; Yorita, K.; Sakai, T.; Fukui, K.
The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia
J. Psychopharmacol. (Oxford)
2009
1-13
2009
Homo sapiens, Mus musculus, Sus scrofa
Tojo, Y.; Hamase, K.; Konno, R.; Koyanagi, S.; Ohdo, S.; Zaitsu, K.
Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis
J. Sep. Sci.
32
430-436
2009
Mus musculus
Verrall, L.; Burnet, P.W.; Betts, J.F.; Harrison, P.J.
The neurobiology of D-amino acid oxidase and its involvement in schizophrenia
Mol. Psychiatry
15
122-137
2009
Homo sapiens
Wirgenes, K.V.; Djurovic, S.; Agartz, I.; Jonsson, E.G.; Werge, T.; Melle, I.; Andreassen, O.A.
Dysbindin and D-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Neuropsychobiology
60
31-36
2009
Homo sapiens
Labrie, V.; Clapcote, S.J.; Roder, J.C.
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors
Pharmacol. Biochem. Behav.
91
610-620
2009
Mus musculus, Mus musculus C57/BL6J
Romano, D.; Molla, G.; Pollegioni, L.; Marinelli, F.
Optimization of human D-amino acid oxidase expression in Escherichia coli
Protein Expr. Purif.
68
72-78
2009
Homo sapiens
Caldinelli, L.; Molla, G.; Sacchi, S.; Pilone, M.S.; Pollegioni, L.
Relevance of weak flavin binding in human D-amino acid oxidase
Protein Sci.
18
801-810
2009
Homo sapiens
Mueller, M.; Kratzer, R.; Schiller, M.; Slavica, A.; Rechberger, G.; Kollroser, M.; Nidetzky, B.
The role of Cys108 in Trigonopsis variabilis D-amino acid oxidase examined through chemical oxidation studies and point mutations C108S and C108D
Biochim. Biophys. Acta
1804
1483-1491
2010
Trigonopsis variabilis, Trigonopsis variabilis ATCC 10679
Katane, M.; Saitoh, Y.; Hanai, T.; Sekine, M.; Furuchi, T.; Koyama, N.; Nakagome, I.; Tomoda, H.; Hirono, S.; Homma, H.
Thiolactomycin inhibits D-aspartate oxidase: a novel approach to probing the active site environment
Biochimie
92
1371-1378
2010
Sus scrofa
Zain, Z.M.; ONeill, R.D.; Lowry, J.P.; Pierce, K.W.; Tricklebank, M.; Dewa, A.; Ab Ghani, S.
Development of an implantable D-serine biosensor for in vivo monitoring using mammalian D-amino acid oxidase on a poly (o-phenylenediamine) and Nafion-modified platinum-iridium disk electrode
Biosens. Bioelectron.
25
1454-1459
2010
Rattus norvegicus
Abad, S.; Nahalka, J.; Winkler, M.; Bergler, G.; Speight, R.; Glieder, A.; Nidetzky, B.
High-level expression of Rhodotorula gracilis D: -amino acid oxidase in Pichia pastoris
Biotechnol. Lett.
33
557-563
2011
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Katane, M.; Saitoh, Y.; Seida, Y.; Sekine, M.; Furuchi, T.; Homma, H.
Comparative characterization of three D-aspartate oxidases and one D-amino acid oxidase from Caenorhabditis elegans
Chem. Biodivers.
7
1424-1434
2010
Caenorhabditis elegans
Konno, R.; Hamase, K.; Maruyama, R.; Zaitsu, K.
Mutant mice and rats lacking D-amino acid oxidase
Chem. Biodivers.
7
1450-1458
2010
Mus musculus, Rattus norvegicus
Chung, S.P.; Sogabe, K.; Park, H.K.; Song, Y.; Ono, K.; Abou El-Magd, R.M.; Shishido, Y.; Yorita, K.; Sakai, T.; Fukui, K.
Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase
J. Biochem.
148
743-753
2010
Rattus norvegicus
Saam, J.; Rosini, E.; Molla, G.; Schulten, K.; Pollegioni, L.; Ghisla, S.
O2 reactivity of flavoproteins: dynamic access of dioxygen to the active site and role of a H+ relay system in D-amino acid oxidase
J. Biol. Chem.
285
24439-24446
2010
Rhodotorula toruloides (P80324)
Abad, S.; Nahalka, J.; Bergler, G.; Arnold, S.A.; Speight, R.; Fotheringham, I.; Nidetzky, B.; Glieder, A.
Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst
Microb. Cell Fact.
9
24
2010
Trigonopsis variabilis (Q6R4Q9), Trigonopsis variabilis
Wong, K.S.; Fong, W.P.; Tsang, P.W.
A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase
New Biotechnol.
27
78-84
2010
Trigonopsis variabilis (Q6R4Q9), Trigonopsis variabilis
Mitchell, J.; Paul, P.; Chen, H.J.; Morris, A.; Payling, M.; Falchi, M.; Habgood, J.; Panoutsou, S.; Winkler, S.; Tisato, V.; Hajitou, A.; Smith, B.; Vance, C.; Shaw, C.; Mazarakis, N.D.; de Belleroche, J.
Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase
Proc. Natl. Acad. Sci. USA
107
7556-7561
2010
Homo sapiens
Caldinelli, L.; Molla, G.; Bracci, L.; Lelli, B.; Pileri, S.; Cappelletti, P.; Sacchi, S.; Pollegioni, L.
Effect of ligand binding on human D-amino acid oxidase: implications for the development of new drugs for schizophrenia treatment
Protein Sci.
19
1500-1512
2010
Homo sapiens (P14920), Homo sapiens
Tan, Q.; Zhang, Y.; Wei, D.
Characterization and stability of D-amino acid oxidase and catalase within the permeabilized recombinant Pichia pastoris cells
Afr. J. Biotechnol.
10
19153-19160
2011
Komagataella pastoris
-
Sacchi, S.; Caldinelli, L.; Cappelletti, P.; Pollegioni, L.; Molla, G.
Structure-function relationships in human D-amino acid oxidase
Amino Acids
43
1833-1850
2012
Homo sapiens
Miyoshi, Y.; Konno, R.; Sasabe, J.; Ueno, K.; Tojo, Y.; Mita, M.; Aiso, S.; Hamase, K.
Alteration of intrinsic amounts of D-serine in the mice lacking serine racemase and D-amino acid oxidase
Amino Acids
43
1919-1931
2012
Mus musculus
Komarova, N.V.; Golubev, I.V.; Khoronenkova, S.V.; Chubar, T.A.; Tishkov, V.I.
Engineering of substrate specificity of D-amino acid oxidase from the yeast Trigonopsis variabilis: directed mutagenesis of Phe258 residue
Biochemistry
77
1181-1189
2012
Trigonopsis variabilis
Raje, M.; Hin, N.; Duvall, B.; Ferraris, D.V.; Berry, J.F.; Thomas, A.G.; Alt, J.; Rojas, C.; Slusher, B.S.; Tsukamoto, T.
Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase
Bioorg. Med. Chem. Lett.
23
3910-3913
2013
Homo sapiens (P14920)
Soma, H.; Furuya, R.; Kaneko, R.; Tsukamoto, A.; Sirasu, K.; Tanigawa, M.; Nagata, Y.
D-Amino acid oxidase and presence of D-proline in Xenopus laevis
Comp. Biochem. Physiol. B
166
165-171
2013
Xenopus laevis
Kopf, J.; Hormigo, D.; Garcia, J.L.; Acebal, C.; de la Mata, I.; Arroyo, M.
Inhibition of recombinant d-amino acid oxidase from Trigonopsis variabilis by salts
Enzyme Res.
2011
158541
2011
Trigonopsis variabilis
Frattini, L.F.; Piubelli, L.; Sacchi, S.; Molla, G.; Pollegioni, L.
Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? Insights from characterization of D-amino acid oxidase
FEBS J.
278
4362-4373
2011
Rattus norvegicus
Hondo, T.; Warizaya, M.; Niimi, T.; Namatame, I.; Yamaguchi, T.; Nakanishi, K.; Hamajima, T.; Harada, K.; Sakashita, H.; Matsumoto, Y.; Orita, M.; Takeuchi, M.
4-Hydroxypyridazin-3(2H)-one derivatives as novel D-amino acid oxidase inhibitors
J. Med. Chem.
56
3582-3592
2013
Homo sapiens
Gisby, M.F.; Mudd, E.A.; Day, A.
Growth of transplastomic cells expressing D-amino acid oxidase in chloroplasts is tolerant to D-alanine and inhibited by D-valine
Plant Physiol.
160
2219-2226
2012
Schizosaccharomyces pombe
Hou, J.; Liu, Y.; Li, Q.; Yang, J.
High activity expression of D-amino acid oxidase in Escherichia coli by the protein expression rate optimization
Protein Expr. Purif.
88
120-126
2013
Trigonopsis variabilis
Pollegioni, L.; Molla, G.
New biotech applications from evolved D-amino acid oxidases
Trends Biotechnol.
29
276-283
2011
Glutamicibacter protophormiae, [Candida] boidinii, Homo sapiens, Rhodotorula toruloides, Trigonopsis variabilis
Ou, Q.; Liu, Y.; Deng, J.; Chen, G.; Yang, Y.; Shen, P.; Wu, B.; Jiang, C.
A novel D-amino acid oxidase from a contaminated agricultural soil metagenome and its characterization
Antonie van Leeuwenhoek
107
1615-1623
2015
uncultured bacterium (A0A0E3JXD9)
Takahashi, S.; Furukawara, M.; Omae, K.; Tadokoro, N.; Saito, Y.; Abe, K.; Kera, Y.
A highly stable d-amino acid oxidase of the thermophilic bacterium Rubrobacter xylanophilus
Appl. Environ. Microbiol.
80
7219-7229
2014
Rubrobacter xylanophilus (A0A077JN67), Rubrobacter xylanophilus
Luks, L.; Sacchi, S.; Pollegioni, L.; Dietrich, D.R.
Novel insights into renal D-amino acid oxidase accumulation propiverine changes DAAO localization and peroxisomal size in vivo
Arch. Toxicol.
91
427-437
2017
Rattus norvegicus
Sacchi, S.
D-Serine metabolism new insights into the modulation of D-amino acid oxidase activity
Biochem. Soc. Trans.
41
1551-1556
2013
Homo sapiens
Hin, N.; Duvall, B.; Berry, J.F.; Ferraris, D.V.; Rais, R.; Alt, J.; Rojas, C.; Slusher, B.S.; Tsukamoto, T.
D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold
Bioorg. Med. Chem. Lett.
26
2088-2091
2016
Homo sapiens
Xie, D.; Lu, J.; Xie, J.; Cui, J.; Li, T.F.; Wang, Y.C.; Chen, Y.; Gong, N.; Li, X.Y.; Fu, L.; Wang, Y.X.
Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent D-amino acid oxidase inhibitor
Eur. J. Med. Chem.
117
19-32
2016
Homo sapiens, Rattus norvegicus, Sus scrofa
Sasabe, J.; Suzuki, M.; Imanishi, N.; Aiso, S.
Activity of D-amino acid oxidase is widespread in the human central nervous system
Front. Synaptic Neurosci.
6
14
2014
Homo sapiens
Chang, S.L.; Hsieh, C.H.; Chen, Y.J.; Wang, C.M.; Shih, C.S.; Huang, P.W.; Mir, A.; Lane, H.Y.; Tsai, G.E.; Chang, H.T.
The C-terminal region of G72 increases D-amino acid oxidase activity
Int. J. Mol. Sci.
15
29-43
2013
Homo sapiens
Du, K.; Sun, J.; Song, X.; Song, C.; Feng, W.
Enhancement of the solubility and stability of D-amino acid oxidase by fusion to an elastin like polypeptide
J. Biotechnol.
212
50-55
2015
Homo sapiens
Hopkins, S.C.; Heffernan, M.L.; Saraswat, L.D.; Bowen, C.A.; Melnick, L.; Hardy, L.W.; Orsini, M.A.; Allen, M.S.; Koch, P.; Spear, K.L.; Foglesong, R.J.; Soukri, M.; Chytil, M.; Fang, Q.K.; Jones, S.W.; Varney, M.A.; Panatier, A.; Oliet, S.H.; Pollegioni, L.; Piubelli, L.; Molla, G.; Nardini, M.; Large, T.H.
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules
J. Med. Chem.
56
3710-3724
2013
Homo sapiens (P14920), Homo sapiens
Hin, N.; Duvall, B.; Ferraris, D.; Alt, J.; Thomas, A.G.; Rais, R.; Rojas, C.; Wu, Y.; Wozniak, K.M.; Slusher, B.S.; Tsukamoto, T.
6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione derivatives as novel D-amino acid oxidase inhibitors
J. Med. Chem.
58
7258-7272
2015
Homo sapiens
Notarangelo, F.M.; Wang, X.D.; Horning, K.J.; Schwarcz, R.
Role of D-amino acid oxidase in the production of kynurenine pathway metabolites from D-tryptophan in mice
J. Neurochem.
136
804-814
2015
Mus musculus
Yoshimoto, M.; Okamoto, M.; Ujihashi, K.; Okita, T.
Selective oxidation of D-amino acids catalyzed by oligolamellar liposomes intercalated with D-amino acid oxidase
Langmuir
30
6180-6186
2014
Sus scrofa
Sasabe, J.; Miyoshi, Y.; Rakoff-Nahoum, S.; Zhang, T.; Mita, M.; Davis, B.M.; Hamase, K.; Waldor, M.K.
Interplay between microbial D-amino acids and host D-amino acid oxidase modifies murine mucosal defence and gut microbiota
Nat. Microbiol.
1
16125
2016
Mus musculus (P18894), Mus musculus
Han, H.; Zhu, B.; Fu, X.; You, S.; Wang, B.; Li, Z.; Zhao, W.; Peng, R.; Yao, Q.
Overexpression of D-amino acid oxidase from Bradyrhizobium japonicum, enhances resistance to glyphosate in Arabidopsis thaliana
Plant Cell Rep.
34
2043-2051
2015
Bradyrhizobium japonicum
Liu, Q.; Chen, L.; Zhang, Z.; Du, B.; Xiao, Y.; Yang, K.; Gong, L.; Wu, L.; Li, X.; He, Y.
pH-Dependent enantioselectivity of D-amino acid oxidase in aqueous solution
Sci. Rep.
7
2994
2017
Sus scrofa
Jiang, J.F.; Qiao, J.; Mu, X.Y.; Moon, M.H.; Qi, L.
Fabrication of enzyme reactor utilizing magnetic porous polymer membrane for screening D-amino acid oxidase inhibitors
Talanta
165
251-257
2017
Sus scrofa
Trimmer, E.E.; Wanninayake, U.S.; Fitzpatrick, P.F.
Mechanistic studies of an amine oxidase derived from D-amino acid oxidase
Biochemistry
56
2024-2030
2017
Sus scrofa (P00371)
Murtas, G.; Caldinelli, L.; Cappelletti, P.; Sacchi, S.; Pollegioni, L.
Human D-amino acid oxidase The inactive G183R variant
Biochim. Biophys. Acta
1866
822-830
2018
Homo sapiens (P14920), Homo sapiens
Szilagyi, B.; Skok, Z.; Racz, A.; Frlan, R.; Ferenczy, G.G.; Ilas, J.; Keseru, G.M.
Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation
Bioorg. Med. Chem. Lett.
28
1693-1698
2018
Homo sapiens (P14920)
Yang, S.
Efficient production of D-amino acid oxidase in Escherichia coli by a trade-off between its expression and biomass using N-terminal modification
Biores. Technol.
243
716-723
2017
Rhodotorula toruloides (P80324), Rhodotorula toruloides
Ahn, M.; Park, S.; Jeon, J.; Choi, J.K.; Khang, Y.
Application of an S-layer protein as a self-aggregating tag for cost-effective separation of recombinant human and yeast D-amino acid oxidases in the aqueous two-phase system
Biotechnol. Lett.
42
241-248
2020
Homo sapiens (P14920), Rhodotorula toruloides (P80324), Rhodotorula toruloides ATCC 26217 (P80324)
Yasukawa, K.; Motojima, F.; Ono, A.; Asano, Y.
Expansion of the substrate specificity of porcine kidney D-amino acid oxidase for S-stereoselective oxidation of 4-Cl-benzhydrylamine
ChemCatChem
10
3500-3505
2018
Sus scrofa (P00371), Sus scrofa
Yasukawa, K.; Kawahara, N.; Motojima, F.; Nakano, S.; Asano, Y.
Porcine kidney D-amino acid oxidase-derived R-amine oxidases with new substrate specificities
Enzymes
47
117-136
2020
Sus scrofa (P00371), Sus scrofa
Kato, Y.; Hin, N.; Maita, N.; Thomas, A.G.; Kurosawa, S.; Rojas, C.; Yorita, K.; Slusher, B.S.; Fukui, K.; Tsukamoto, T.
Structural basis for potent inhibition of D-amino acid oxidase by thiophene carboxylic acids
Eur. J. Med. Chem.
159
23-34
2018
Homo sapiens (P14920), Homo sapiens
Rosini, E.; Caldinelli, L.; Piubelli, L.
Assays of D-amino acid oxidase activity
Front. Mol. Biosci.
4
102
2017
Homo sapiens (P14920), Rhodotorula toruloides (P80324)
Murtas, G.; Sacchi, S.; Valentino, M.; Pollegioni, L.
Biochemical properties of human D-amino acid oxidase
Front. Mol. Biosci.
4
88
2017
Homo sapiens (P14920), Homo sapiens
Murtas, G.; Sacchi, S.; Pollegioni, L.
Substitution of arginine 120 in human D-amino acid oxidase favors FAD-binding and nuclear mistargeting
Front. Mol. Biosci.
6
125
2019
Homo sapiens (P14920), Homo sapiens
Jagannath, V.; Brotzakis, Z.; Parrinello, M.; Walitza, S.; Gruenblatt, E.
Controversial effects of D-amino acid oxidase activator (DAOA)/G72 on D-amino acid oxidase (DAO) activity in human neuronal, astrocyte and kidney cell lines The N-methyl D-aspartate (NMDA) receptor hypofunction point of view
Front. Mol. Neurosci.
10
342
2017
Homo sapiens
Jagannath, V.; Marinova, Z.; Monoranu, C.; Walitza, S.; Gruenblatt, E.
Expression of D-amino acid oxidase (DAO/DAAO) and D-amino acid oxidase activator (DAOA/G72) during development and aging in the human post-mortem brain
Front. Neuroanat.
11
31
2017
Homo sapiens (P14920), Homo sapiens
Rachadech, W.; Kato, Y.; Abou El-Magd, R.M.; Shishido, Y.; Kim, S.H.; Sogabe, H.; Maita, N.; Yorita, K.; Fukui, K.
P219L substitution in human D-amino acid oxidase impacts the ligand binding and catalytic efficiency
J. Biochem.
168
557-567
2020
Homo sapiens (P14920), Homo sapiens
Kim, S.; Shishido, Y.; Sogabe, H.; Rachadech, W.; Yorita, K.; Kato, Y.; Fukui, K.
Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues Implication for aging and neurodegeneration
J. Biochem.
25
187-196
2020
Mus musculus (P18894), Mus musculus
Padhi, A.; Hazra, S.
Insights into the role of D-amino acid oxidase mutations in amyotrophic lateral sclerosis
J. Cell. Biochem.
120
2180-2197
2019
Homo sapiens (P14920), Homo sapiens
Taniguchi, S.; Chosrowjan, H.; Ito, S.; Miyasaka, H.; Katane, M.; Homma, H.; Tanaka, F.; Nueangaudom, A.; Lugsanangarm, K.; Kokpol, S.
Comparative studies on picosecond-resolved fluorescence of D-amino acid oxidases from human with one from porcine kidney. Photoinduced electron transfer from aromatic amino acids to the excited flavin
J. Photochem. Photobiol. B
198
111546
2019
Homo sapiens (P14920), Homo sapiens, Sus scrofa (P00371), Sus scrofa
Szilagyi, B.; Hargitai, C.; Kelemen, A.A.; Racz, A.; Ferenczy, G.G.; Volk, B.; Keseru, G.M.
Synthesis and biochemical evaluation of lid-open D-amino acid oxidase inhibitors
Molecules
24
290
2019
Homo sapiens (P14920)
Kohiki, T.; Kato, Y.; Nishikawa, Y.; Yorita, K.; Sagawa, I.; Denda, M.; Inokuma, T.; Shigenaga, A.; Fukui, K.; Otaka, A.
Elucidation of inhibitor-binding pockets of d-amino acid oxidase using docking simulation and N-sulfanylethylanilide-based labeling technology
Org. Biomol. Chem.
15
5289-5297
2017
Homo sapiens (P14920)
Kiss, D.J.; Ferenczy, G.G.
A detailed mechanism of the oxidative half-reaction of D-amino acid oxidase another route for flavin oxidation
Org. Biomol. Chem.
17
7973-7984
2019
Rhodotorula toruloides (P80324)
Kondori, N.; Paul, P.; Robbins, J.; Liu, K.; Hildyard, J.; Wells, D.; De Belleroche, J.
Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase Phenotype and loss of spinal cord motor neurons
PLoS ONE
12
e0188912
2017
Homo sapiens (P14920)
Subramanian, K.; Gora, A.; Spruijt, R.; Mitusinska, K.; Suarez-Diez, M.; Martins Dos Santos, V.; Schaap, P.J.
Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access
PLoS ONE
13
e0198990
2018
Sus scrofa (P00371), Sus scrofa, Homo sapiens (P14920), Homo sapiens
Padhi, A.; Zhang, K.
Mechanistic insights into the loss-of-function mechanisms of rare human D-amino acid oxidase variants implicated in amyotrophic lateral sclerosis
Sci. Rep.
10
17146
2020
Homo sapiens (P14920), Homo sapiens
Lin, C.H.; Yang, H.T.; Chiu, C.C.; Lane, H.Y.
Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging
Sci. Rep.
7
14849
2017
Homo sapiens (P14920), Homo sapiens
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