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Reference on EC 1.4.1.4 - glutamate dehydrogenase (NADP+)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hatanaka, M.; Tachiki, T.; Kumagai, H.; Tochikura, T.
Distribution and some properties of glutamine synthetase and glutamate dehydrogenase in Bifidobacteria
Agric. Biol. Chem.
51
251-252
1987
Bifidobacterium adolescentis, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium longum subsp. infantis, Bifidobacterium longum, Bifidobacterium pseudolongum, Bifidobacterium thermophilum
-
Manually annotated by BRENDA team
Ma, K.; Robb, F.T.; Adams, M.W.
Purification and characterization of NADP-specific alcohol dehydrogenase and glutamate dehydrogenase from the hyperthermophilic archaeon Thermococcus litoralis
Appl. Environ. Microbiol.
60
562-568
1994
Thermococcus litoralis
Manually annotated by BRENDA team
Hemmil, I.A.; Mntsl, P.I.
Purification and properties of glutamate synthase and glutamate dehydrogenase from Bacillus megaterium
Biochem. J.
173
45-52
1978
Priestia megaterium
Manually annotated by BRENDA team
Lebbink, J.H.; Knapp, S.; van der Oost, J.; Rice, D.; Ladenstein, R.; de Vos, W.M.
Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface
J. Mol. Biol.
289
357-369
1999
Thermotoga maritima
Manually annotated by BRENDA team
Bhuiya, M.W.; Sakuraba, H.; Ohshima, T.
Temperature dependence of kinetic parameters for hyperthermophilic glutamate dehydrogenase from Aeropyrum pernix K1
Biosci. Biotechnol. Biochem.
66
873-876
2002
Aeropyrum pernix K1, Aeropyrum pernix K1 JCM 9820
Manually annotated by BRENDA team
Robb, F.T.; Maeder, D.L.; DiRuggiero, J.; Borges, K.M.; Tolliday, N.
Glutamate dehydrogenases from hyperthermophiles
Methods Enzymol.
331
26-41
2001
Thermococcus litoralis
Manually annotated by BRENDA team
Steen, I.H.; Hvoslef, H.; Lien, T.; Birkeland, N.K.
Isocitrate dehydrogenase, malate dehydrogenase, and glutamate dehydrogenase from Archaeoglobus fulgidus
Methods Enzymol.
331
13-26
2001
Archaeoglobus fulgidus
Manually annotated by BRENDA team
DeLuna, A.; Avendano, A.; Riego, L.; Gonzalez, A.
NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles
J. Biol. Chem.
276
43775-43783
2001
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Helianti, I.; Morita, Y.; Yamamura, A.; Murakami, Y.; Yokoyama, K.; Tamiya, E.
Characterization of native glutamate dehydrogenase from an aerobic hyperthermophilic archaeon Aeropyrum pernix K1
Appl. Microbiol. Biotechnol.
56
388-394
2001
Aeropyrum pernix K1
Manually annotated by BRENDA team
Di Fraia, R.; Wilquet, V.; Ciardiello, M.A.; Carratore, V.; Antignani, A.; Camardella, L.; Glansdorff, N.; Di Prisco, G.
NADP+-dependent glutamate dehydrogenase in the Antarctic psychrotolerant bacterium Psychrobacter sp. TAD1. Characterization, protein and DNA sequence, and relationship to other glutamate dehydrogenases
Eur. J. Biochem.
267
121-131
2000
Escherichia coli, Psychrobacter sp., Escherichia coli DH5-alpha, Psychrobacter sp. TAD1
Manually annotated by BRENDA team
Bhuiya, M.W.; Sakuraba, H.; Kujo, C.; Nunoura-Kominato, N.; Kawarabayasi, Y.; Kikuchi, H.; Ohshima, T.
Glutamate dehydrogenase from the aerobic hyperthermophilic archaeon Aeropyrum pernix K1: enzymatic characterization, identification of the encoding gene, and phylogenetic implications
Extremophiles
4
333-341
2000
Aeropyrum pernix, Aeropyrum pernix (Q9YC65), Aeropyrum pernix K1, Aeropyrum pernix DSM 11879 (Q9YC65)
Manually annotated by BRENDA team
Rahman, R.N.Z.A.; Fujiwara, S.; Nakamura, H.; Takagi, M.; Imanaka, T.
Ion pairs involved in maintaining a thermostable structure of glutamate dehydrogenase from a hyperthermophilic archaeon
Biochem. Biophys. Res. Commun.
248
920-926
1998
Thermococcus kodakarensis
Manually annotated by BRENDA team
Park, J.H.; Schofield, P.J.; Edwards, M.R.
Giardia intestinalis: characterization of a NADP-dependent glutamate dehydrogenase
Exp. Parasitol.
88
131-138
1998
Giardia intestinalis
Manually annotated by BRENDA team
Aalen, N.; Steen, I.H.; Birkeland, N.K.; Lien, T.
Purification and properties of an extremely thermostable NADP+-specific glutamate dehydrogenase from Archaeoglobus fulgidus
Arch. Microbiol.
168
536-539
1997
Archaeoglobus fulgidus, Archaeoglobus fulgidus 7324
Manually annotated by BRENDA team
Inokuchi, R.; Itagaki, T.; Wiskich, J.T.; Nakayama, K.; Okada, M.
An NADP-glutamate dehydrogenase from the green alga Bryopsis maxima. Purification and properties
Plant Cell Physiol.
38
327-335
1997
Bryopsis maxima
Manually annotated by BRENDA team
Ferrer, J.; Perez-Pomares, F.; Bonete, M.J.
NADP-glutamate dehydrogenase from the halophilic archaeon Haloferax mediterranei: enzyme purification, N-terminal sequence and stability studies
FEMS Microbiol. Lett.
141
59-63
1996
Haloferax mediterranei, Haloferax mediterranei DSM 1411
Manually annotated by BRENDA team
Koike, K.; Hakamada, Y.; Yoshimatsu, T.; Kobayashi, T.; Ito, S.
NADP-specific glutamate dehydrogenase from alkalophilic Bacillus sp. KSM-635: purification and enzymic properties
Biosci. Biotechnol. Biochem.
60
1764-1767
1996
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) KSM-635
Manually annotated by BRENDA team
Bogati, M.S.; Pocsi, I.; Maticsek, J.; Boross, P.; Tozser, J.; Szentirmai, A.
NADP-specific glutamate dehydrogenase of Penicillium chrysogenum has a homohexamer structure
J. Basic Microbiol.
36
371-375
1996
Penicillium chrysogenum, Penicillium chrysogenum NCAIM 00237
Manually annotated by BRENDA team
Krauth-Siegel, R.L.; Mueller, J.G.; Lottspeich, F.; Schirmer, R.H.
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria
Eur. J. Biochem.
235
345-350
1996
Plasmodium falciparum
Manually annotated by BRENDA team
Kobayashi, T.; Higuchi, S.; Kimura, K.; Kudo, T.; Horikoshi, K.
Properties of glutamate dehydrogenase and its involvement in alanine production in a hyperthermophilic archaeon, Thermococcus profundus
J. Biochem.
118
587-592
1995
Thermococcus profundus
Manually annotated by BRENDA team
Baars, J.J.P.; Op den Camp, H.J.M.; van Hoek, A.H.A.M.; van der Drift, C.; Van Griensven, L.J.L.D.; Visser, J.; Vogels, G.D.
Purification and characterization of NADP-dependent glutamate dehydrogenase from the commercial mushroom Agaricus bisporus
Curr. Microbiol.
30
211-217
1995
Agaricus bisporus
Manually annotated by BRENDA team
Lebbink, J.H.G.; Eggen, R.I.L.; Geerling, A.C.M.; Consalvi, V.; Chiaraluce, R.; Scandurra, R.; de Vos, W.M.
Exchange of domains of glutamate dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus and the mesophilic bacterium Clostridium difficile: Effects on catalysis, thermoactivity and stability
Protein Eng.
8
1287-1294
1995
Clostridioides difficile, Pyrococcus furiosus
Manually annotated by BRENDA team
Perysinakis, A.; Kinghorn, J.R.; Drainas, C.
Biochemical and genetical studies of NADP-specific glutamate dehydrogenase in the fission yeast Schizosaccharomyces pombe
Curr. Genet.
26
315-320
1994
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Korber, F.C.; Rizkallah, P.J.; Attwood, T.K.; Wootton, J.C.; McPherson, M.J.; North, A.C.; Geddes, A.J.; Abeysinghe, I.S.; Baker, P.J.; Dean, J.L.; et al.
Crystallization of the NADP(+)-dependent glutamate dehydrogenase from Escherichia coli
J. Mol. Biol.
234
1270-1273
1993
Escherichia coli
Manually annotated by BRENDA team
Ohshima, T.; Nishida, N.
Purification and properties of extremely thermostable glutamate dehydrogenase from two hyperthermophilic archaebacteria, Pyrococcus woesei and Pyrococcus furiosus
Biosci. Biotechnol. Biochem.
57
945-951
1993
Pyrococcus furiosus, Pyrococcus woesei
Manually annotated by BRENDA team
Hudson, R.C.; Ruttersmith, L.D.; Daniel, R.M.
Glutamate dehydrogenase from the extremely thermophilic archaebacterial isolate AN1
Biochim. Biophys. Acta
1202
244-250
1993
Thermococcus sp.
Manually annotated by BRENDA team
Lin, H.P.P.; Reeves, H.C.
Purification and characterization of NADP+-specific glutamate dehydrogenase from Escherichia coli
Curr. Microbiol.
22
371-376
1991
Escherichia coli
Manually annotated by BRENDA team
Pamula, F.; Wheldrake, J.F.
Purification and properties of the NADP-dependent glutamate dehydrogenase from Dictyostelium discoideum
Mol. Cell. Biochem.
105
85-92
1991
Dictyostelium discoideum
Manually annotated by BRENDA team
Bonete, M.J.; Camacho, M.L.; Candenas, E.
Analysis of the kinetic mechanism of halophilic NADP-dependent glutamate dehydrogenase
Biochim. Biophys. Acta
1041
305-310
1990
Halobacterium salinarum, Halobacterium salinarum NRC 36014
Manually annotated by BRENDA team
Op den Camp, H.J.M.; Liem, K.D.; Meesters, P.; Hermans, J.M.H.; van der Drift, C.
Purification and characterization of the NADP-dependent glutamate dehydrogenase from Bacillus fastidiosus
Antonie van Leeuwenhoek
55
303-311
1989
Metabacillus fastidiosus
Manually annotated by BRENDA team
Vancurova, I.; Vancura, A.; Volc, J.; Kopecky, J.; Neuzil, J.; Basarova, G.; Behal, V.
Purification and properties of NADP-dependent glutamate dehydrogenase from Streptomyces fradiae
J. Gen. Microbiol.
135
3311-3318
1989
Streptomyces fradiae
Manually annotated by BRENDA team
Lilley, K.S.; Hornby, D.P.; Engel, P.C.
Purification, chemical modification and analysis of pH-dependence of the NADP+-dependent glutamate dehydrogenase of Escherichia coli
Biochem. Soc. Trans.
16
876-877
1988
Escherichia coli, Escherichia coli K2
-
Manually annotated by BRENDA team
Martinez-Bilbao, M.; Martinez, A.; Urkijo, I.; Llama, M.J.; Serra, J.L.
Induction, isolation, and some properties of the NADPH-dependent glutamate dehydrogenase from the nonheterocystous cyanobacterium Phormidium laminosum
J. Bacteriol.
170
4897-4902
1988
Phormidium laminosum
Manually annotated by BRENDA team
Turner, A.C.; Lushbaugh, W.B.
Trichomonas vaginalis: characterization of its glutamate dehydrogenase
Exp. Parasitol.
67
47-53
1988
Trichomonas vaginalis
Manually annotated by BRENDA team
Bascomb, N.F.; Schmidt, R.R.
Purification and partial kinetic and physical characterization of two chloroplast-localized NADP-specific glutamate dehydrogenase isoenzymes and their preferential accumulation in Chlorella sorokiniana cells cultured at low or high ammonium levels
Plant Physiol.
83
75-84
1987
Chlorella sorokiniana
Manually annotated by BRENDA team
Weining, S.; Nicholas, D.J.D.
Purification and properties of NADP+-dependent glutamate dehydrogenase from Nitrobacter hamburgensis strain X14
Phytochemistry
26
2151-2153
1987
Nitrobacter hamburgensis, Nitrobacter hamburgensis X14
-
Manually annotated by BRENDA team
Florencio, F.J.; Marques, S.; Candau, P.
Identification and characterization of a glutamate dehydrogenase in the unicellular cyanobacterium Synechocystis PCC 6803
FEBS Lett.
223
37-41
1987
Synechocystis sp.
-
Manually annotated by BRENDA team
Catmull, J.; Yellowlees, D.; Miller, D.J.
NADP+-dependent glutamate dehydrogenase from Acropora formosa
Mar. Biol.
95
559-563
1987
Acropora formosa
-
Manually annotated by BRENDA team
Cioni, P.; Cavaliere, M.G.; Fissi, A.; Balestreri, E.; Felicioli, R.
Glutamate dehydrogenase from E.coli kinetic structural and regulation studies
Ital. J. Biochem.
35
175A-177A
1986
Escherichia coli
-
Manually annotated by BRENDA team
Misono, H.; Goto, N.; Nagasaki, S.
Purification, crystallization and properties of NADP+-specific glutamate dehydrogenase from Lactobacillus fermentum
Agric. Biol. Chem.
49
117-123
1985
Enterococcus faecalis, Limosilactobacillus fermentum, Lactococcus lactis, Streptococcus equinus, Streptococcus equinus IFO 12553, Lactococcus lactis IFO 12546, Enterococcus faecalis IFO 12964, Limosilactobacillus fermentum IFO 3071
-
Manually annotated by BRENDA team
Agrawal, A.K.; Rao, V.K.M.
Kinetic studies on glutamate dehydrogenase of Aspergillus ochraceus
Indian J. Biochem. Biophys.
21
386-388
1984
Aspergillus ochraceus, Aspergillus ochraceus ATCC
Manually annotated by BRENDA team
Botton, B.; Msatef, Y.
Purification and properties of NADP-dependent glutamate dehydrogenase from Sphaerostilbe repens
Physiol. Plant.
59
438-444
1983
Corallomycetella repens
-
Manually annotated by BRENDA team
Sarada, K.V.; Rao, N.A.; Venkitasubramanian, T.A.
Isolation and characterisation of glutamate dehydrogenase from Mycobacterium smegmatis CDC 46
Biochim. Biophys. Acta
615
299-308
1980
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis CDC46
Manually annotated by BRENDA team
Shimizu, H.; Kuratsu, T.; Hirata, F.
Purification and some properties of glutamate dehydrogenase from Proteus inconstans
J. Ferment. Technol.
57
428-433
1979
Proteus inconstans
-
Manually annotated by BRENDA team
Leicht, W.; Werber, M.M.; Eisenberg, H.
Purification and characterization of glutamate dehydrogenase from Halobacterium of the Dead Sea
Biochemistry
17
4004-4010
1978
Halobacterium sp.
Manually annotated by BRENDA team
Juan, S.M.; Segura, E.L.; Cazzulo, J.J.
Purification and some properties of the NADP-linked glutamate dehydrogenase from Trypanosoma cruzi
Int. J. Biochem.
9
395-400
1978
Trypanosoma cruzi
Manually annotated by BRENDA team
Camardella, L.; di Prisco, G.; Garofano, F.; Guerrini, A.M.
Purification and properties of NADP-dependent glutamate dehydrogenase from yeast nuclear fractions
Biochim. Biophys. Acta
429
324-330
1976
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Veronese, F.M.; Boccu, E.; Conventi, L.
Glutamate dehydrogenase from Escherichia coli: induction, purification and properties of the enzyme
Biochim. Biophys. Acta
377
217-228
1975
Escherichia coli, Escherichia coli MRE 600
Manually annotated by BRENDA team
Sakamoto, N.; Kotre, A.M.; Savageau, M.A.
Glutamate dehydrogenase from Escherichia coli: purification and properties
J. Bacteriol.
124
775-783
1975
Escherichia coli
Manually annotated by BRENDA team
Epstein, I.; Grossowicz, N.
Purification and properties of glutamate dehydrogenase from a thermophilic bacillus
J. Bacteriol.
122
1257-1264
1975
Thermophilic bacillus
Manually annotated by BRENDA team
Coulton, J.W.; Kapoor, M.
Purification and some properties of the glutamate dehydrogenase of Salmonella typhimurium
Can. J. Microbiol.
19
427-438
1973
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Coulton, J.W.; Kapoor, M.
Studies on the kinetics and regulation of glutamate dehydrogenase of Salmonella typhimurium
Can. J. Microbiol.
19
439-450
1973
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Amin, A.; Joshi, M.; Deshpande, M.V.
Morphology-associated expression of NADP-dependent glutamate dehydrogenases during yeast-mycelium transition of a dimorphic fungus Benjaminiella poitrasii
Antonie van Leeuwenhoek
85
327-334
2004
Benjaminiella poitrasii
Manually annotated by BRENDA team
deLuna, A.; Quezada, H.; Gomez-Puyou, A.; Gonzalez, A.
Asparaginyl deamidation in two glutamate dehydrogenase isoenzymes from Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
328
1083-1090
2005
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Lebbink, J.H.; Consalvi, V.; Chiaraluce, R.; Berndt, K.D.; Ladenstein, R.
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability
Biochemistry
41
15524-15535
2002
Thermotoga maritima
Manually annotated by BRENDA team
de Morais, M.A., Jr.
The NADP+-dependent glutamate dehydrogenase of the yeast Kluyveromyces marxianus responds to nitrogen repression similarly to Saccharomyces cerevisiae
Braz. J. Microbiol.
34
334-338
2003
Kluyveromyces marxianus, Kluyveromyces marxianus CBS6556
-
Manually annotated by BRENDA team
Camardella, L.; di Fraia, R.; Antignani, A.; Ciardiello, M.A.; di Prisco, G.; Coleman, J.K.; Buchon, L.; Guespin, J.; Russell, N.J.
The antarctic Psychrobacter sp. TAD1 has two cold-active glutamate dehydrogenases with different cofactor specificities. Characterisation of the NAD+-dependent enzyme
Comp. Biochem. Physiol. A
131A
559-567
2002
Psychrobacter sp., Psychrobacter sp. TAD1
-
Manually annotated by BRENDA team
Alba-Lois, L.; Segal, C.; Rodarte, B.; Valdes-Lopez, V.; DeLuna, A.; Cardenas, R.
NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii
Curr. Microbiol.
48
68-72
2004
Debaryomyces hansenii, Debaryomyces hansenii Y7426
Manually annotated by BRENDA team
Ingoldsby, L.M.; Geoghegan, K.F.; Hayden, B.M.; Engel, P.C.
The discovery of four distinct glutamate dehydrogenase genes in a strain of Halobacterium salinarum
Gene
349
237-244
2005
Halobacterium salinarum
Manually annotated by BRENDA team
Kim, Y.J.; Yoshizawa, M.; Takenaka, S.; Murakami, S.; Aoki, K.
Ammonia assimilation in Klebsiella pneumoniae F-5-2 that can utilize ammonium and nitrate ions simultaneously: purification and characterization of glutamate dehydrogenase and glutamine synthetase
J. Biosci. Bioeng.
93
584-588
2002
Klebsiella pneumoniae, Klebsiella pneumoniae F-5-2
Manually annotated by BRENDA team
Ha, J.S.; Kim, K.; Song, J.J.; Bae, J.W.; Lee, S.G.; Lee, S.C.; Poo, H.; Shin, C.S.; Sung, M.H.
Thermostable glutamate dehydrogenase from a commensal thermophile,Symbiobacterium toebii; overproduction, characterization, and application
J. Mol. Catal. B
26
231-240
2003
Symbiobacterium toebii
-
Manually annotated by BRENDA team
Pagliarulo, C.; Salvatore, P.; de Vitis, L.R.; Colicchio, R.; Monaco, C.; Tredici, M.; Tala, A.; Bardaro, M.; Lavitola, A.; Bruni, C.B.; Alifano, P.
Regulation and differential expression of gdhA encoding NADP-specific glutamate dehydrogenase in Neisseria meningitidis clinical isolates
Mol. Microbiol.
51
1757-1772
2004
Neisseria meningitidis
Manually annotated by BRENDA team
Lawit, S.J.; Miller, P.W.; Dunn, W.I.; Mirabile, J.S.; Schmidt, R.R.
Heterologous expression of cDNAs encoding Chlorella sorokiniana NADP-specific glutamate dehydrogenase wild-type and mutant subunits in Escherichia coli cells and comparison of kinetic and thermal stability properties of their homohexamers
Plant Mol. Biol.
52
605-616
2003
Chlorella sorokiniana
Manually annotated by BRENDA team
Kisaka, H.; Kida, T.
Transgenic tomato plant carrying a gene for NADP-dependent glutamate dehydrogenase (gdhA) from Aspergillus nidulans
Plant Sci.
164
35-42
2003
Aspergillus nidulans
-
Manually annotated by BRENDA team
Tanous, C.; Chambellon, E.; Le Bars, D.; Delespaul, G.; Yvon, M.
Glutamate dehydrogenase activity can be transmitted naturally to Lactococcus lactis strains to stimulate amino acid conversion to aroma compounds
Appl. Environ. Microbiol.
72
1402-1409
2006
Lactococcus lactis, Lactococcus lactis NCDO1867
Manually annotated by BRENDA team
Jaspard, E.
A computational analysis of the three isoforms of glutamate dehydrogenase reveals structural features of the isoform EC 1.4.1.4 supporting a key role in ammonium assimilation by plants
Biol. Direct
1
38
2006
Chlorella sorokiniana (P28998), Chlorella sorokiniana
Manually annotated by BRENDA team
Rosario, C.J.; Bender, R.A.
Importance of tetramer formation by the nitrogen assimilation control protein for strong repression of glutamate dehydrogenase formation in Klebsiella pneumoniae
J. Bacteriol.
187
8291-8299
2005
Klebsiella pneumoniae, Klebsiella pneumoniae MK53
Manually annotated by BRENDA team
Werner, C.; Stubbs, M.T.; Krauth-Siegel, R.L.; Klebe, G.
The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugs
J. Mol. Biol.
349
597-607
2005
Plasmodium falciparum
Manually annotated by BRENDA team
Noor, S.; Punekar, N.S.
Allosteric NADP-glutamate dehydrogenase from aspergilli: purification, characterization and implications for metabolic regulation at the carbon-nitrogen interface
Microbiology
151
1409-1419
2005
Aspergillus awamori, Aspergillus nidulans, Aspergillus niger, Aspergillus oryzae, Aspergillus terreus, Saccharomyces cerevisiae, Aspergillus oryzae NCIM 553, Aspergillus nidulans NCIM 1211, Aspergillus niger NCIM 565, Aspergillus awamori NCIM 1225, Aspergillus terreus NCIM 656
Manually annotated by BRENDA team
Morel, M.; Buee, M.; Chalot, M.; Brun, A.
NADP-dependent glutamate dehydrogenase: a dispensable function in ectomycorrhizal fungi
New Phytol.
169
179-190
2006
Cenococcum geophilum, Cenococcum geophilum H5-3, Hebeloma bulbiferum, Hebeloma cylindrosporum (Q96UJ9), Laccaria amethystina, Laccaria bicolor (P54388), Laccaria bicolor S238N (P54388), no activity in Amanita citrina, no activity in Amanita muscaria, no activity in Amanita muscaria MAN, no activity in Boletus edulis, no activity in Boletus edulis Hub 0, no activity in Lactarius quietus, no activity in Lactarius subdulcis, no activity in Lactarius subdulcis BRI 2, no activity in Paxillus involutus, no activity in Pisolithus tinctorius, no activity in Pisolithus tinctorius 441, no activity in Rhizopogon luteolus, no activity in Rhizopogon luteolus SERRE, no activity in Scleroderma citrinum, no activity in Scleroderma citrinum Foug A, no activity in Suillus bovinus, no activity in Suillus bovinus LED 1, no activity in Thelephora terrestris, no activity in Thelephora terrestris CHA, no activity in Tricholoma populinum, no activity in Tricholoma populinum BLAE, no activity in Xerocomus chrysenteron, Tuber borchii (Q9HFR6)
Manually annotated by BRENDA team
Benachenhou-Lahfa, N.; Labedan, B.; Forterre, P.
PCR-mediated cloning and sequencing of the gene encoding glutamate dehydrogenase from the archaeon Sulfolobus shibatae: identification of putative amino-acid signatures for extremophilic adaptation.
Gene
140
17-24
1994
Saccharolobus shibatae (P39475)
Manually annotated by BRENDA team
Sharkey, M.A.; Engel, P.C.
Apparent negative co-operativity and substrate inhibition in overexpressed glutamate dehydrogenase from Escherichia coli
FEMS Microbiol. Lett.
281
132-139
2008
Escherichia coli
Manually annotated by BRENDA team
Tanous, C.; Chambellon, E.; Yvon, M.
Sequence analysis of the mobilizable lactococcal plasmid pGdh442 encoding glutamate dehydrogenase activity
Microbiology
153
1664-1675
2007
Lactococcus lactis, Lactococcus lactis NCDO1867
Manually annotated by BRENDA team
Thykaer, J.; Rueksomtawin, K.; Noorman, H.; Nielsen, J.
NADPH-dependent glutamate dehydrogenase in Penicillium chrysogenum is involved in regulation of beta-lactam production
Microbiology
154
1242-1250
2008
Penicillium chrysogenum, Penicillium chrysogenum DS12975
Manually annotated by BRENDA team
Souza, S.L.; Gennari, S.M.; Richtzenhain, L.J.; Pena, H.F.; Funada, M.R.; Cortez, A.; Gregori, F.; Soares, R.M.
Molecular identification of Giardia duodenalis isolates from humans, dogs, cats and cattle from the state of Sao Paulo, Brazil, by sequence analysis of fragments of glutamate dehydrogenase (gdh) coding gene
Vet. Parasitol.
149
258-264
2007
Giardia intestinalis (P28724)
Manually annotated by BRENDA team
Joshi, C.V.; Ghormade, V.; Kunde, P.; Kulkarni, P.; Mamgain, H.; Bhat, S.; Paknikar, K.M.; Deshpande, M.V.
Flocculation of dimorphic yeast Benjaminiella poitrasii is altered by modulation of NAD-glutamate dehydrogenase
Biores. Technol.
101
1393-1395
2009
Benjaminiella poitrasii
Manually annotated by BRENDA team
Choi, M.M.; Kim, E.A.; Huh, J.W.; Choi, S.Y.; Cho, S.W.; Yang, S.J.
Small-interfering-RNA-mediated silencing of human glutamate dehydrogenase induces apoptosis in neuroblastoma cells
Biotechnol. Appl. Biochem.
51
107-110
2008
Homo sapiens
Manually annotated by BRENDA team
Choudhury, R.; Noor, S.; Varadarajalu, L.; Punekar, N.
Delineation of an in vivo inhibitor for Aspergillus glutamate dehydrogenase
Enzyme Microb. Technol.
42
151-159
2008
Aspergillus niger
Manually annotated by BRENDA team
Thykaer, J.; Rueksomtawin, K.; Noorman, H.; Nielsen, J.
Disruption of the NADPH-dependent glutamate dehydrogenase affects the morphology of two industrial strains of Penicillium chrysogenum
J. Biotechnol.
139
280-282
2009
Penicillium chrysogenum
Manually annotated by BRENDA team
Vamsee-Krishna, C.; Phale, P.S.
Carbon source-dependent modulation of NADP-glutamate dehydrogenases in isophthalate-degrading Pseudomonas aeruginosa strain PP4, Pseudomonas strain PPD and Acinetobacter lwoffii strain ISP4
Microbiology
154
3329-3337
2008
Acinetobacter lwoffii, Pseudomonas aeruginosa
Manually annotated by BRENDA team
Rodriguez-Saiz, M.; Godio, R.P.; Alvarez, V.; de la Fuente, J.L.; Martin, J.F.; Barredo, J.L.
The NADP-dependent glutamate dehydrogenase gene from the astaxanthin producer Xanthophyllomyces dendrorhous: use of its promoter for controlled gene expression
Mol. Biotechnol.
41
165-172
2009
Phaffia rhodozyma (C6EVR5), Phaffia rhodozyma
Manually annotated by BRENDA team
Choudhury, R.; Punekar, N.S.
Aspergillus terreus NADP-glutamate dehydrogenase is kinetically distinct from the allosteric enzyme of other Aspergilli
Mycol. Res.
113
1121-1126
2009
Aspergillus niger, Aspergillus terreus
Manually annotated by BRENDA team
Qiu, X.; Xie, W.; Lian, X.; Zhang, Q.
Molecular analyses of the rice glutamate dehydrogenase gene family and their response to nitrogen and phosphorous deprivation
Plant Cell Rep.
28
1115-1126
2009
Oryza sativa
Manually annotated by BRENDA team
Sharkey, M.A.; Engel, P.C.
Modular coenzyme specificity: a domain-swopped chimera of glutamate dehydrogenase
Proteins
77
268-278
2009
Escherichia coli
Manually annotated by BRENDA team
Harper, C.J.; Hayward, D.; Kidd, M.; Wiid, I.; van Helden, P.
Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis
BMC Microbiol.
10
138
2010
Mycolicibacterium smegmatis (A0R3E3), Mycolicibacterium smegmatis
Manually annotated by BRENDA team
De Angelis, M.; Calasso, M.; Di Cagno, R.; Siragusa, S.; Minervini, F.; Gobbetti, M.
NADP-glutamate dehydrogenase activity in nonstarter lactic acid bacteria: effects of temperature, pH and NaCl on enzyme activity and expression
J. Appl. Microbiol.
109
1763-1774
2010
Lactiplantibacillus plantarum (Q2WCS9), Lactiplantibacillus plantarum DPPMA49 (Q2WCS9)
Manually annotated by BRENDA team
Vamsee-Krishna, C.; Phale, P.S.
Bypassing isophthalate inhibition by modulating glutamate dehydrogenase (GDH): purification and kinetic characterization of NADP-GDHs from isophthalate-degrading Pseudomonas aeruginosa strain PP4 and Acinetobacter lwoffii strain ISP4
J. Bacteriol.
192
801-806
2010
Acinetobacter lwoffii, Pseudomonas aeruginosa, Pseudomonas aeruginosa PP4, Acinetobacter lwoffii ISP4
Manually annotated by BRENDA team
Consalvi, V.; Chiaraluce, R.; Politi, L.; Vaccaro, R.; De Rosa, M.; Scandurra, R.
Extremely thermostable glutamate dehydrogenase from the hyperthermophilic archaebacterium Pyrococcus furiosus
Eur. J. Biochem.
202
1189-1196
1991
Pyrococcus furiosus
Manually annotated by BRENDA team
Sun, M.M.; Tolliday, N.; Vetriani, C.; Robb, F.T.; Clark, D.S.
Pressure-induced thermostabilization of glutamate dehydrogenase from the hyperthermophile Pyrococcus furiosus
Protein Sci.
8
1056-1063
1999
Pyrococcus furiosus
Manually annotated by BRENDA team
Wakamatsu, T.; Higashi, C.; Ohmori, T.; Doi, K.; Ohshima, T.
Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from a hyperthermophilic archaeon Pyrobaculum calidifontis
Extremophiles
17
379-389
2013
Pyrobaculum calidifontis (A3MWK6), Pyrobaculum calidifontis JCM 11548 (A3MWK6)
Manually annotated by BRENDA team
Sharkey, M.A.; Oliveira, T.F.; Engel, P.C.; Khan, A.R.
Structure of NADP(+) -dependent glutamate dehydrogenase from Escherichia coli - reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases
FEBS J.
280
4681-4692
2013
Escherichia coli (P00370)
Manually annotated by BRENDA team
Lee, Y.J.; Kim, K.J.; Kang, H.Y.; Kim, H.R.; Maeng, P.J.
Involvement of GDH3-encoded NADP+-dependent glutamate dehydrogenase in yeast cell resistance to stress-induced apoptosis in stationary phase cells
J. Biol. Chem.
287
44221-44233
2012
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Manually annotated by BRENDA team
Tang, Y.; Sieg, A.; Trotter, P.J.
13C-metabolic enrichment of glutamate in glutamate dehydrogenase mutants of Saccharomyces cerevisiae
Microbiol. Res.
166
521-530
2011
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Zocher, K.; Fritz-Wolf, K.; Kehr, S.; Fischer, M.; Rahlfs, S.; Becker, K.
Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2
Mol. Biochem. Parasitol.
183
52-62
2012
Plasmodium falciparum (Q8ILF7), Plasmodium falciparum (Q8ILT0)
Manually annotated by BRENDA team
Abiko, T.; Wakayama, M.; Kawakami, A.; Obara, M.; Kisaka, H.; Miwa, T.; Aoki, N.; Ohsugi, R.
Changes in nitrogen assimilation, metabolism, and growth in transgenic rice plants expressing a fungal NADP(H)-dependent glutamate dehydrogenase (gdhA)
Planta
232
299-311
2010
Aspergillus niger
Manually annotated by BRENDA team
Sedelnikova, S.E.; Yip, K.S.; Stillman, T.J.; Ma, K.; Adams, M.W.; Robb, F.T.; Rice, D.W.
Crystallization of the glutamate dehydrogenase from the hyperthermophilic archaeon Thermococcus litoralis
Acta Crystallogr. Sect. D
52
1185-1187
1996
Thermococcus litoralis (Q56304), Thermococcus litoralis, Thermococcus litoralis DSM 5473 (Q56304)
Manually annotated by BRENDA team
Bhuiya, M.W.; Tsuge, H.; Sakuraba, H.; Yoneda, K.; Katunuma, N.; Ohshima, T.
Crystallization and preliminary X-ray diffraction analysis of glutamate dehydrogenase from an aerobic hyperthermophilic archaeon, Aeropyrum pernix K1
Acta Crystallogr. Sect. D
58
1338-1339
2002
Aeropyrum pernix, Aeropyrum pernix DSM 11879
Manually annotated by BRENDA team
Lee, M.K.; Gonzalez, J.M.; Robb, F.T.
Extremely thermostable glutamate dehydrogenase (GDH) from the freshwater archaeon Thermococcus waiotapuensis: cloning and comparison with two marine hyperthermophilic GDHs
Extremophiles
6
151-159
2002
Thermococcus waiotapuensis (Q977X9)
Manually annotated by BRENDA team
Ferrer, J.; Cremades, R.; Pire, C.; Bonete, M.J.
Fluorescence and quenching comparative studies of halophilic and bovine glutamate dehydrogenase
J. Photochem. Photobiol. B
47
148-154
1998
Bos taurus, Haloferax mediterranei
Manually annotated by BRENDA team
Sun, M.M.; Caillot, R.; Mak, G.; Robb, F.T.; Clark, D.S.
Mechanism of pressure-induced thermostabilization of proteins: studies of glutamate dehydrogenases from the hyperthermophile Thermococcus litoralis
Protein Sci.
10
1750-1757
2001
Thermococcus litoralis (Q56304), Thermococcus litoralis DSM 5473 (Q56304)
Manually annotated by BRENDA team
Prakash, P.; Walvekar, A.; Punekar, N.; Bhaumik, P.
Purification, crystallization and preliminary X-ray diffraction analysis of NADP-dependent glutamate dehydrogenase from Aspergillus niger
Acta Crystallogr. Sect. F
70
1508-1512
2014
Aspergillus niger
Manually annotated by BRENDA team
Oliveira, T.; Sharkey, M.; Engel, P.; Khan, A.
Crystal structure of a chimaeric bacterial glutamate dehydrogenase
Acta Crystallogr. Sect. F
72
462-466
2016
Escherichia coli (P00370)
Manually annotated by BRENDA team
Zhu, J.; Lu, K.; Xu, X.; Wang, X.; Shi, J.
Purification and characterization of a novel glutamate dehydrogenase from Geotrichum candidum with higher alcohol and amino acid activity
AMB Express
7
009
2017
Geotrichum candidum, Geotrichum candidum S12
Manually annotated by BRENDA team
Son, H.F.; Kim, I.K.; Kim, K.J.
Structural insights into domain movement and cofactor specificity of glutamate dehydrogenase from Corynebacterium glutamicum
Biochem. Biophys. Res. Commun.
459
387-392
2015
Corynebacterium glutamicum (P31026), Corynebacterium glutamicum ATCC 13032 (P31026)
Manually annotated by BRENDA team
Geng, F.; Ma, C.W.; Zeng, A.P.
Reengineering substrate specificity of E. coli glutamate dehydrogenase using a position-based prediction method
Biotechnol. Lett.
39
599-605
2017
Escherichia coli (Q8XDW9)
Manually annotated by BRENDA team
Garcia-Galan, C.; Barbosa, O.; Fernandez-Lafuente, R.
Stabilization of the hexameric glutamate dehydrogenase from Escherichia coli by cations and polyethyleneimine
Enzyme Microb. Technol.
52
211-217
2013
Escherichia coli
Manually annotated by BRENDA team
Tian, G.; Wang, Q.; Wei, X.; Ma, X.; Chen, S.
Glutamate dehydrogenase (RocG) in Bacillus licheniformis WX-02 Enzymatic properties and specific functions in glutamic acid synthesis for poly-?-glutamic acid production
Enzyme Microb. Technol.
99
9-15
2017
Bacillus licheniformis (AKQ74236), Bacillus licheniformis WX-02 (AKQ74236)
Manually annotated by BRENDA team
Wakamatsu, T.; Higashi, C.; Ohmori, T.; Doi, K.; Ohshima, T.
Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from a hyperthermophilic archaeon Pyrobaculum calidifontis
Extremophiles
17
379-389
2013
Pyrobaculum calidifontis (A3MWK6), Pyrobaculum calidifontis JCM 11548 (A3MWK6)
Manually annotated by BRENDA team
Tomita, T.; Yin, L.; Nakamura, S.; Kosono, S.; Kuzuyama, T.; Nishiyama, M.
Crystal structure of the 2-iminoglutarate-bound complex of glutamate dehydrogenase from Corynebacterium glutamicum
FEBS Lett.
591
1611-1622
2017
Corynebacterium glutamicum (A0A0U4QBJ6), Corynebacterium glutamicum ATCC 13869 (A0A0U4QBJ6)
Manually annotated by BRENDA team
Ballester-Tomas, L.; Randez-Gil, F.; Perez-Torrado, R.; Prieto, J.A.
Redox engineering by ectopic expression of glutamate dehydrogenase genes links NADPH availability and NADH oxidation with cold growth in Saccharomyces cerevisiae
Microb. Cell Fact.
14
100
2015
Saccharomyces cerevisiae (P07262)
Manually annotated by BRENDA team
Downes, D.J.; Davis, M.A.; Kreutzberger, S.D.; Taig, B.L.; Todd, R.B.
Regulation of the NADP-glutamate dehydrogenase gene gdhA in Aspergillus nidulans by the Zn(II)2Cys6 transcription factor LeuB
Microbiology
159
2467-2480
2013
Aspergillus nidulans (P18819), Aspergillus nidulans, Aspergillus nidulans ATCC 38163 (P18819)
Manually annotated by BRENDA team
Campero-Basaldua, C.; Quezada, H.; Riego-Ruiz, L.; Marquez, D.; Rojas, E.; Gonzalez, J.; El-Hafidi, M.; Gonzalez, A.
Diversification of the kinetic properties of yeast NADP-glutamate-dehydrogenase isozymes proceeds independently of their evolutionary origin
MicrobiologyOpen
6
e00419
2017
Saccharomyces cerevisiae, Lachancea kluyveri, Saccharomyces cerevisiae CLA1
Manually annotated by BRENDA team
Campero-Basaldua, C.; Quezada, H.; Riego-Ruiz, L.; Marquez, D.; Rojas, E.; Gonzalez, J.; El-Hafidi, M.; Gonzalez, A.
Diversification of the kinetic properties of yeast NADP-glutamate-dehydrogenase isozymes proceeds independently of their evolutionary origin
MicrobiologyOpen
6
doi: 10.1002/mbo3.419
2017
Kluyveromyces lactis
Manually annotated by BRENDA team
Zhang, H.; Liang, C.; Aoki, N.; Kawai, K.; Takane, K.; Ohsugi, R.
Introduction of a fungal NADP(H)-dependent glutamate dehydrogenase (gdhA) improves growth, grain weight and salt resistance by enhancing the nitrogen uptake efficiency in forage rice
Plant Prod. Sci.
19
267-278
2016
Aspergillus niger
-
Manually annotated by BRENDA team
Walvekar, A.S.; Choudhury, R.; Punekar, N.S.
Mixed disulfide formation at Cys141 leads to apparent unidirectional attenuation of Aspergillus niger NADP-glutamate dehydrogenase activity
PLoS ONE
9
e101662
2014
Aspergillus niger (B6V7E4), Aspergillus niger
Manually annotated by BRENDA team
Hou, W.; Lu, S.; Zhao, H.; Yu, Y.; Xu, H.; Yu, B.; Su, L.; Lin, C.; Ruan, B.H.
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP+ binding site
Biochem. Biophys. Res. Commun.
509
262-267
2019
Escherichia coli (P00370)
Manually annotated by BRENDA team
Li, N.; Wang, W.; Zeng, X.; Liu, M.; Li, M.; Li, C.; Wang, M.
Crystal structure of glutamate dehydrogenase 3 from Candida albicans
Biochem. Biophys. Res. Commun.
570
15-20
2021
Candida albicans (A0A1D8PMH8), Candida albicans, Candida albicans ATCC MYA-2876 (A0A1D8PMH8)
Manually annotated by BRENDA team
Pathan, E.; Kulkarni, A.; Prasanna, N.; Ramana, C.; Deshpande, M.
NADP-dependent glutamate dehydrogenases in a dimorphic zygomycete Benjaminiella poitrasii purification, characterization and their evaluation as an antifungal drug target
Biochim. Biophys. Acta
1864
129696
2020
Benjaminiella poitrasii (A0A076N6W1), Benjaminiella poitrasii (A0A076V390), Benjaminiella poitrasii, Benjaminiella poitrasii NCIM 1240 (A0A076N6W1), Benjaminiella poitrasii NCIM 1240 (A0A076V390)
Manually annotated by BRENDA team
Du, C.Q.; Lin, J.Z.; Dong, L.A.; Liu, C.; Tang, D.Y.; Yan, L.; Chen, M.D.; Liu, S.; Liu, X.M.
Overexpression of an NADP(H)-dependent glutamate dehydrogenase gene, TrGDH, from Trichurus improves nitrogen assimilation, growth status and grain weight per plant in rice
Breed. Sci.
69
429-438
2019
Trichurus sp.
Manually annotated by BRENDA team
Sato, K.; Kamijo, T.; Takahashi, S.; Sato, T.
Comparison of NAD with NADP-dependent glutamate dehydrogenase, and CNT with rGO-modified electrodes, for the construction of glutamate sensors
Electroanalysis
30
2237-2240
2018
Proteus sp. G4468 (A0A845TU58)
-
Manually annotated by BRENDA team
Pathan, E.K.; Ghormade, V.; Panwar, S.L.; Prasad, R.; Deshpande, M.V.
Molecular studies of NAD- and NADP-glutamate dehydrogenases decipher the conundrum of yeast-hypha dimorphism in zygomycete Benjaminiella poitrasii
FEMS Yeast Res.
19
foz074
2019
Benjaminiella poitrasii (A0A385P597), Benjaminiella poitrasii (A0A385P5J9), Benjaminiella poitrasii
Manually annotated by BRENDA team
Lee, W.H.; Oh, J.Y.; Maeng, P.J.
The NADP+-dependent glutamate dehydrogenase Gdh1 is subjected to glucose starvation-induced reversible aggregation that affects stress resistance in yeast
J. Microbiol.
57
884-892
2019
Saccharomyces cerevisiae (P07262), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P07262)
Manually annotated by BRENDA team
Mara, P.; Fragiadakis, G.S.; Gkountromichos, F.; Alexandraki, D.
The pleiotropic effects of the glutamate dehydrogenase (GDH) pathway in Saccharomyces cerevisiae
Microb. Cell Fact.
17
170
2018
Saccharomyces cerevisiae (P07262), Saccharomyces cerevisiae (P39708), Saccharomyces cerevisiae ATCC 204508 (P07262), Saccharomyces cerevisiae ATCC 204508 (P39708)
Manually annotated by BRENDA team
Han, T.; Cannon, R.; Gallo, S.; Villas-Boas, S.
A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis
NPJ Biofilms Microbiomes
5
13
2019
Candida albicans (A0A1D8PMH8), Candida albicans, Candida albicans ATCC MYA-2876 (A0A1D8PMH8)
Manually annotated by BRENDA team
Xian, L.; Zhang, Y.; Cao, Y.; Wan, T.; Gong, Y.; Dai, C.; Ochieng, W.A.; Nasimiyu, A.T.; Li, W.; Liu, F.
Glutamate dehydrogenase plays an important role in ammonium detoxification by submerged macrophytes
Sci. Total Environ.
722
137859
2020
Myriophyllum spicatum, Potamogeton lucens
Manually annotated by BRENDA team
Trotter, P.J.; Juco, K.; Le, H.T.; Nelson, K.; Tamayo, L.I.; Nicaud, J.M.; Park, Y.K.
Glutamate dehydrogenases in the oleaginous yeast Yarrowia lipolytica
Yeast
37
103-115
2020
Yarrowia lipolytica (Q6C1A9), Yarrowia lipolytica, Yarrowia lipolytica CLIB 122 (Q6C1A9), Yarrowia lipolytica E 150 (Q6C1A9)
Manually annotated by BRENDA team