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Information on EC 1.3.1.74 - 2-alkenal reductase [NAD(P)+]

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IUBMB Comments
Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of alpha,beta-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)].
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
double bond reductase, alkenal/one oxidoreductase, nadph-dependent alkenal/one oxidoreductase, at5g16970, alkenal/one reductase, ataor, at-aer, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a n-alkanal + NAD(P)+ = an alk-2-enal + NAD(P)H + H+
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