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1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
1,1,1,2-tetrachloroethane + reduced acceptor
1,1-dichlorethene + chloride + acceptor
1,1,1-trichloroethane + reduced acceptor
1,1-dichloroethane + chloride + acceptor
-
-
-
?
1,1,2,2-tetrachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
1,1,2-trichloroethane + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
1,1,2-trichloroethene + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
1,1,3-trichloro-1-propene + Ti(III) citrate
1,1-dichloro-1-propene + Cl- + ?
-
-
-
-
?
1,1,3-trichloropropene + reduced acceptor
1,1-dichloropropene + chloride + acceptor
-
22.9% activity compared with perchloroethene as substrate
-
-
?
1,1-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
1,2,4,5-tetrachlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
1,2,4,5-tetrachlorobenzene + reduced methyl viologen
1,2,4-trichlorobenzene + chloride + methyl viologen
-
-
-
-
?
1,2,4-trichlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
1,2,4-trichlorobenzene + reduced methyl viologen
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + methyl viologen
-
-
-
-
?
1,2-dichloropropane + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
2,3-dichloro-1-propene + Ti(III) citrate
2-chloropropene + Cl- + ?
-
as a side product, 2,5-dichloro-1,5-hexadiene is formed demonstrating that the reductive dechlorination of 2,3-dichloropropene proceeds via a radical reaction mechanism
-
-
?
2,3-dichlorophenol + reduced acceptor
2-chlorophenol + chloride + oxidized acceptor
2,3-dichloropropene + reduced acceptor
2-chloropropene + chloride + acceptor
-
14.4% activity compared with perchloroethene as substrate
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
2,4,6-trichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
2,4-dichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
3,5-dichlorophenol + reduced acceptor
? + chloride + oxidized acceptor
-
-
-
?
bromoform + reduced acceptor
dibromomethane + chloride + acceptor
-
-
-
?
chlorinated propenes + reduced acceptor
propene + chloride + acceptor
-
22% of the reduction rates with perchloroethene
-
-
?
chloroacetamide + reduced acceptor
acetamide + chloride + acceptor
-
very poor substrate
-
-
?
chloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
chloroform + reduced acceptor
dichloromethane + chloride + acceptor
-
-
-
?
cis-1,2-dichloroethene + reduced acceptor
monochloroethene + chloride + acceptor
-
-
-
-
?
cis-1,2-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
cis-1,3-dichloropropene + reduced acceptor
mono-chloropropene + chloride + acceptor
-
chlorination rate is lower than for trans-1,3-dichloropropene and reaction ceases after 2-3 min
-
?
dichloroethene + reduced acceptor
chloroethene + chloride + acceptor
-
-
-
-
?
hexachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
monochloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
pentachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + 2 H2
cis-1,2-dichloroethene + 2 chloride + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
tetrachloroethene + reduced acceptor
trans-1,2 dichloroethene + acceptor + 2 chloride
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
tetrachloroethene + reduced benzylviologen
trichloroethene + chloride + benzylviologen
-
-
-
-
?
tetrachloroethene + reduced cobaltocene
trichloroethene + chloride + cobaltocene
-
-
-
-
?
tetrachloroethene + reduced ethyl viologen
cis-1,2-dichloroethene + chloride + ethyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
trichloroethene + chloride + methyl viologen
-
-
-
?
tetrachloroethene + reduced methylviologen
trichloroethene + chloride + methylviologen
tetrachloromethane + reduced acceptor
? + chloride + acceptor
-
very poor substrate
-
-
?
tetraiodoethene + reduced acceptor
triiodoethene + iodide + acceptor
-
reaction rate is considerably slower than with tetrachloroethene
-
-
?
trans-1,2-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
trans-1,3-dichloropropene + reduced acceptor
mono-chloropropene + chloride + acceptor
-
5.7% activity compared with perchloroethene as substrate
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
trichloroethene + reduced acceptor
dichloroethene + chloride + acceptor
-
-
-
-
?
additional information
?
-
1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
-
-
-
-
?
1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
-
-
-
-
?
1,1,1,2-tetrachloroethane + reduced acceptor
1,1-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,1,2-tetrachloroethane + reduced acceptor
1,1-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2,2-tetrachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2,2-tetrachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2-trichloroethene + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2-trichloroethene + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,3-dichlorophenol + reduced acceptor
2-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,3-dichlorophenol + reduced acceptor
2-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,6-trichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,6-trichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4-dichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4-dichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trans-1,2 dichloroethene + acceptor + 2 chloride
dechlorination activity of tetrachloroethene to trans-1,2 dichloroethene is detected after 24 h of incubating the corresponding unstained gel fragment
-
-
?
tetrachloroethene + reduced acceptor
trans-1,2 dichloroethene + acceptor + 2 chloride
dechlorination activity of tetrachloroethene to trans-1,2 dichloroethene is detected after 24 h of incubating the corresponding unstained gel fragment
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
lipophilic solvent tetrachloroethene, one of the most abundant halogenated xenobiotic pollutants in the environment
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
quite specific for tetrachloroethene
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
besides reduced methyl viologen, titanium(III)citrate can serve as electron donor for reductive dehalogenation
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methylviologen
trichloroethene + chloride + methylviologen
-
-
-
-
?
tetrachloroethene + reduced methylviologen
trichloroethene + chloride + methylviologen
-
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
?
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
-
r
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
good substrate, comparable to tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
70% of activity compared with tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
good substrate, comparable to tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
poor substrate, 10% of the rate of tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
besides reduced methyl viologen, titanium(III)citrate can serve as electron donor for reductive dehalogenation
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
additional information
?
-
trichlofluoroethene, tetrachloromethane, hexachloroethane, tetrachloroethane, trichloroethane, and 1,1,1-trichloro-2,2,2-trifluoroethane cause an enzyme dependent oxidation of reduced methyl viologen
-
-
?
additional information
?
-
-
trichlofluoroethene, tetrachloromethane, hexachloroethane, tetrachloroethane, trichloroethane, and 1,1,1-trichloro-2,2,2-trifluoroethane cause an enzyme dependent oxidation of reduced methyl viologen
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
no activity with trichloroethene, TCE, cis-dichloroethene, cis-DCE, or vinyl chloride
-
-
?
additional information
?
-
-
enzyme quite specific
-
-
?
additional information
?
-
-
very low activity with reduced benzyl viologen
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
-
-
?
additional information
?
-
-
enzyme quite specific
-
-
?
additional information
?
-
-
very high substrate specificity
-
-
?
additional information
?
-
-
no activity with other chloroethenes or chloromethanes or chlorinated aromatic compounds, no activity with carbon tetrachloride, 1,1-dichloroethene, trans-1,2-dichloroethene, cis-1,2-dichloroethene, 3-chlorobenzoate, 3-chloro-4-hydroxyphenol, pentachlorophenol, 2,4,6-trichlorophenol, 2,4,5-trichlorophenol
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
-
the enzyme shows no dihaloelimination activity towards 1,1,2-trichloroethane or 1,1,1-trichloroethane
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
-
-
?
additional information
?
-
-
the enzyme shows no dihaloelimination activity towards 1,1,2-trichloroethane or 1,1,1-trichloroethane
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
broad substrate specificity, degrades various chlorinated aliphatic compounds
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
broad substrate specificity, degrades various chlorinated aliphatic compounds
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
additional information
?
-
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
no activity with other chloroethenes, chloroethanes or chloromethanes, no activity with 1,1-dichloroethene, trans-1,2-dichloroethene, 1,1,1-trichloroethane, 1,1,1-trichloroacetone, hexachloroethane, and the chlorinated aromatic compounds 3-chlorobenzoate, 4-chlorophenol, and 3,4-dichlorobenzoate
-
-
?
additional information
?
-
-
no activity with dichloroethene, 1-chloropropene, 2-chloropropene, 3-chloropropene, 1,1-dichloropropene, 1,2-dichloropropane, 1,3-dichloropropane, and 1,2,3-trichloropropane
-
-
?
additional information
?
-
-
anaerobic growth in presence of dimethylbenzimidazole leads to replacement of the adenine moiety in the nucleotide loop of cofoactor norpseudo-B12 by dimethylbenzimidazole. The formation of the dimethylbenzimidazole-containing nor-B12 severely affects tetrachloroethene-dependent growth and the PceA activity. In dimethylbenzimidazole-treated cells processing of the cytoplasmic PceA precursor is impeded. PceA enriched from cells cultivated with dimethylbenzimidazole contains nor-B12. Nor-B12 purified from cells grown in the presence of dimethylbenzimidazole mediates the abiotic reductive dehalogenation of trichloroacetate to dichloroacetate at a 25fold lower rate in comparison with norpseudo-B12
-
-
?
additional information
?
-
-
dehalogenation of tetrachloroethene results in a similar extent of C and Cl isotope fractionation, and in similar dual element isotope slopes for PceA enzyme and for abiotic dehylogenation by corrinoids. Catalytic dehalogenation by enzymes and different corrinoids display mechanistic and/or kinetic differences
-
-
?
additional information
?
-
-
anaerobic growth in presence of dimethylbenzimidazole leads to replacement of the adenine moiety in the nucleotide loop of cofoactor norpseudo-B12 by dimethylbenzimidazole. The formation of the dimethylbenzimidazole-containing nor-B12 severely affects tetrachloroethene-dependent growth and the PceA activity. In dimethylbenzimidazole-treated cells processing of the cytoplasmic PceA precursor is impeded. PceA enriched from cells cultivated with dimethylbenzimidazole contains nor-B12. Nor-B12 purified from cells grown in the presence of dimethylbenzimidazole mediates the abiotic reductive dehalogenation of trichloroacetate to dichloroacetate at a 25fold lower rate in comparison with norpseudo-B12
-
-
?
additional information
?
-
-
dehalogenation of tetrachloroethene results in a similar extent of C and Cl isotope fractionation, and in similar dual element isotope slopes for PceA enzyme and for abiotic dehylogenation by corrinoids. Catalytic dehalogenation by enzymes and different corrinoids display mechanistic and/or kinetic differences
-
-
?
additional information
?
-
no substrate: trichloroethene
-
-
?
additional information
?
-
-
in homogeneous aqueous solution containing titanium(III) citrate or titanium(III)-nitrilotriacetic acid as bulk electron donor, cobalamin, cobinamide, and cobamide are effective electron transfer mediators for the reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene. For a given chlorinated ethene, the reaction rate varies only slightly with pH and type of corrinoid present and is about 5 and 50 times faster for tetrachloroethene as compared to trichlorofluoroethene and trichloroethene, respectively. The first and rate-limiting step of the reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene by super-reduced corrinoids is a dissociative one-electron transfer yielding the corresponding vinyl radicals
-
-
?
additional information
?
-
using pull-down assays PceA1 interacts with DnaK (Hsp70)
-
-
?
additional information
?
-
using pull-down assays PceA1 interacts with DnaK (Hsp70)
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1,2,4,5-tetrachlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
1,2,4-trichlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
chloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
cis-1,2-dichloroethene + reduced acceptor
monochloroethene + chloride + acceptor
-
-
-
-
?
dichloroethene + reduced acceptor
chloroethene + chloride + acceptor
-
-
-
-
?
monochloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + 2 H2
cis-1,2-dichloroethene + 2 chloride + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
trichloroethene + reduced acceptor
dichloroethene + chloride + acceptor
-
-
-
-
?
additional information
?
-
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE, physiological electron donor is not known
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
additional information
?
-
using pull-down assays PceA1 interacts with DnaK (Hsp70)
-
-
?
additional information
?
-
using pull-down assays PceA1 interacts with DnaK (Hsp70)
-
-
?
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1998
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163
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-
brenda
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178
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2002
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brenda
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brenda
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brenda
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127
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2005
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brenda
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Electroenzymatic reactions. Investigation of a reductive dehalogenase by means of electrogenerated redox cosubstrates
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127
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2005
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brenda
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Biochemical and molecular characterization of a tetrachloroethene dechlorinating Desulfitobacterium sp. strain Y51: a review
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32
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2005
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Evidence for a radical mechanism of the dechlorination of chlorinated propenes mediated by the tetrachloroethene reductive dehalogenase of Sulfurospirillum multivorans
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Sulfurospirillum multivorans
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Cloning of a novel dehalogenase from environmental DNA
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74
1290-1292
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uncultured bacterium (D6RU53), uncultured bacterium (D6RU55)
brenda
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Identification and transcriptional analysis of trans-DCE-producing reductive dehalogenases in Dehalococcoides species
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4
1020-1030
2010
Dehalococcoides sp. (D6MZ08), Dehalococcoides sp. MB (D6MZ08)
brenda
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Impact of vitamin B12 on formation of the tetrachloroethene reductive dehalogenase in Desulfitobacterium hafniense strain Y51
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78
8025-8032
2012
Desulfitobacterium hafniense, Desulfitobacterium hafniense Y51
brenda
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Functional genotyping of Sulfurospirillum spp. in mixed cultures allowed the identification of a new tetrachloroethene reductive dehalogenase
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79
6941-6947
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brenda
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Exogenous 5,6-dimethylbenzimidazole caused production of a non-functional tetrachloroethene reductive dehalogenase in Sulfurospirillum multivorans
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16
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2014
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brenda
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Identification of a reductive tetrachloroethene dehalogenase in Shewanella sediminis
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20120326
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Functional heterologous production of reductive dehalogenases from Desulfitobacterium hafniense strains
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Corrinoid-mediated reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene in homogeneous aqueous solution: Reaction kinetics and reaction mechanisms
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1997
synthetic construct
-
brenda
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Combined C and Cl isotope effects indicate differences between corrinoids and enzyme (Sulfurospirillum multivorans PceA) in reductive dehalogenation of tetrachloroethene, but not trichloroethene
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11837-11845
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brenda
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93
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2016
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brenda
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Reductive dechlorination in the energy metabolism of anaerobic bacteria
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uncultured bacterium
-
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101
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brenda
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Identification of multiple dehalogenase genes involved in tetrachloroethene-to-ethene dechlorination in a Dehalococcoides-dominated enrichment culture
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2017
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brenda
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22
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brenda
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brenda
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284
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brenda
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Reductive tetrachloroethene dehalogenation in the presence of oxygen by Sulfurospirillum multivorans physiological studies and proteome analysis
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2018
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brenda
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brenda
Alfan-Guzman, R.; Ertan, H.; Manefield, M.; Lee, M.
Isolation and characterization of Dehalobacter sp. strain TeCB1 including identification of TcbA a novel tetra- and trichlorobenzene reductive dehalogenase
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brenda
Matturro, B.; Presta, E.; Rossetti, S.
Reductive dechlorination of tetrachloroethene in marine sediments Biodiversity and dehalorespiring capabilities of the indigenous microbes
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445-452
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Dehalococcoides mccartyi
brenda