Disease on EC 1.21.99.3 - thyroxine 5-deiodinase
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma, Follicular
Thyroid hormone deiodinases--a selenoenzyme family acting as gate keepers to thyroid hormone action.
Adenoma
Expression of 5'-deiodinase enzymes in normal pituitaries and in various human pituitary adenomas.
Arthritis, Rheumatoid
In vivo effect of gold compounds on thyroxine to triiodothyronine conversion by type I 5'-deiodinase in patients with rheumatoid arthritis.
Blindness
Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice.
Breast Diseases
The Pattern of Expression and Role of Triiodothyronine (T3) Receptors and Type I 5'-Deiodinase in Breast Carcinomas, Benign Breast Diseases, Lactational Change, and Normal Breast Epithelium.
Breast Neoplasms
The Pattern of Expression and Role of Triiodothyronine (T3) Receptors and Type I 5'-Deiodinase in Breast Carcinomas, Benign Breast Diseases, Lactational Change, and Normal Breast Epithelium.
Diabetes Mellitus
Pituitary-thyroid axis in short- and long-term experimental diabetes mellitus.
Diabetes Mellitus, Experimental
Autoradiographic thyroid evaluation in short-term experimental diabetes mellitus.
Encephalomyelitis, Autoimmune, Experimental
Inflammation severely alters thyroid hormone signaling in the central nervous system during experimental allergic encephalomyelitis in rat: Direct impact on OPCs differentiation failure.
Euthyroid Sick Syndromes
A potential role of activated NF-kappa B in the pathogenesis of euthyroid sick syndrome.
Euthyroid Sick Syndromes
Euthyroid sick syndrome and inhibitory effect of sera on the activity of thyroid 5'-deiodinase in systemic sclerosis.
Euthyroid Sick Syndromes
Immunoneutralization of interleukin-1, tumor necrosis factor, interleukin-6 or interferon does not prevent the LPS-induced sick euthyroid syndrome in mice.
Euthyroid Sick Syndromes
Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia.
Euthyroid Sick Syndromes
Thyroid hormone metabolism and level of illness severity in pediatric cardiac surgery patients.
Gastrointestinal Stromal Tumors
Consumptive hypothyroidism due to a gastrointestinal stromal tumor expressing type 3 iodothyronine deiodinase.
Gestational Trophoblastic Disease
Loss of Selenoprotein Iodothyronine Deiodinase 3 Expression Correlates with Progression of Complete Hydatidiform Mole to Gestational Trophoblastic Neoplasia.
Graves Disease
Thyroid T4 5'-deiodinase activity in normal and abnormal human thyroid glands.
Hemangioendothelioma
Severe hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother.
Hemangioma
Difficult treatment of consumptive hypothyroidism in a child with massive parotid hemangioma.
Hemangioma
Increased type 3 iodothyronine deiodinase activity in a regrown hepatic hemangioma with consumptive hypothyroidism.
Hemangioma
New insight into the pathophysiology of severe hypothyroidism in an infant with multiple hepatic hemangiomas.
Hemangioma
Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas.
Hemangioma
Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas.
Hemangioma
Vincristine for successful treatment of steroid-dependent infantile hemangiomas.
Hydatidiform Mole
Loss of Selenoprotein Iodothyronine Deiodinase 3 Expression Correlates with Progression of Complete Hydatidiform Mole to Gestational Trophoblastic Neoplasia.
Hyperthyroidism
Effects of thyroid and glucocorticoid hormones on the level of messenger ribonucleic acid for iodothyronine type I 5'-deiodinase in rat primary hepatocyte cultures grown as spheroids.
Hyperthyroidism
Multigenerational Disruption of the Thyroid Endocrine System in Marine Medaka after a Life-Cycle Exposure to Perfluorobutanesulfonate.
Hyperthyroidism
Parent-of-origin allelic contributions to deiodinase-3 expression elicit localized hyperthyroid milieu in the hippocampus.
Hyperthyroidism
Relative developmental toxicities of pentachloroanisole and pentachlorophenol in a zebrafish model (Danio rerio).
Hyperthyroidism
Thyroxine type II 5'-deiodinase activity in pineal and Harderian gland is enhanced by hypothyroidism but is independent of serum thyroxine concentrations during hyperthyroidism.
Hypothyroidism
5'-Deiodinase type 1 activity in liver and brain of the thyroxine-treated dystrophic hamster.
Hypothyroidism
A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase.
Hypothyroidism
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
Hypothyroidism
Alpha 1- and beta-adrenergic receptors in brown adipose tissue and the adrenergic regulation of thyroxine 5'-deiodinase.
Hypothyroidism
Comparative study of pituitary-thyroid hormone economy in fasting and hypothyroid rats.
Hypothyroidism
Consumptive hypothyroidism caused by paraneoplastic production of type 3 iodothyronine deiodinase.
Hypothyroidism
Consumptive hypothyroidism due to a gastrointestinal stromal tumor expressing type 3 iodothyronine deiodinase.
Hypothyroidism
Consumptive hypothyroidism resulting from hepatic vascular tumors in an athyreotic adult.
Hypothyroidism
Demonstration of thyromimetic effects of 3,5,3'-triiodothyronine sulfate (T3S) in euthyroid rats.
Hypothyroidism
Developmental changes in rat brain 5'-deiodinase and thyroid hormones during the fetal period: the effects of fetal hypothyroidism and maternal thyroid hormones.
Hypothyroidism
Difficult treatment of consumptive hypothyroidism in a child with massive parotid hemangioma.
Hypothyroidism
Effect of the cardiac inotropic drug, OPC 8212, on pituitary-thyroid function in the rat.
Hypothyroidism
Effects of thyroid and glucocorticoid hormones on the level of messenger ribonucleic acid for iodothyronine type I 5'-deiodinase in rat primary hepatocyte cultures grown as spheroids.
Hypothyroidism
Functional evidence for the presence of type II 5'-deiodinase in somatotropes and its adaptive role in hypothyroidism.
Hypothyroidism
Increased type 3 iodothyronine deiodinase activity in a regrown hepatic hemangioma with consumptive hypothyroidism.
Hypothyroidism
Modification of thermogenic capacity in neonatal pigs by changes in thyroid status during late gestation.
Hypothyroidism
New insight into the pathophysiology of severe hypothyroidism in an infant with multiple hepatic hemangiomas.
Hypothyroidism
Regulation of thyroxine 5'-deiodinase activity by 3,5,3'-triiodothyronine in cultured rat anterior pituitary cells.
Hypothyroidism
Regulation of thyroxine 5'-deiodinase by thyroid hormones and activators of protein kinase C in GH4C1 cells.
Hypothyroidism
Severe hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother.
Hypothyroidism
Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas.
Hypothyroidism
Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas.
Hypothyroidism
Studies of molecular mechanisms associated with increased deiodinase 3 expression in a case of consumptive hypothyroidism.
Hypothyroidism
Thyroid hormones and 5'-deiodinase in the rat fetus late in gestation: effects of maternal hypothyroidism.
Hypothyroidism
Thyroxine type II 5'-deiodinase activity in pineal and Harderian gland is enhanced by hypothyroidism but is independent of serum thyroxine concentrations during hyperthyroidism.
Hypothyroidism
Transthyretin regulates thyroid hormone levels in the choroid plexus, but not in the brain parenchyma: study in a transthyretin-null mouse model.
Hypothyroidism
Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy.
Hypothyroidism
Vincristine for successful treatment of steroid-dependent infantile hemangiomas.
Infections
Induced illness in interleukin-6 (IL-6) knock-out mice: a causal role of IL-6 in the development of the low 3,5,3'-triiodothyronine syndrome.
Insulinoma
Glucagon-like peptide-1 stimulates type 3 iodothyronine deiodinase expression in a mouse insulinoma cell line.
Kashin-Beck Disease
Effects of methylation of deiodinase 3 gene on gene expression and severity of Kashin-Beck disease.
Ketosis
Relationship between inhibitor of extrathyroidal 5'-deiodinase activity and serum free fatty acid in children with nonthyroidal illness and acute ketosis.
Leber Congenital Amaurosis
Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice.
Multiple Endocrine Neoplasia Type 2a
Preparation with iopanoic acid rapidly controls thyrotoxicosis in patients with amiodarone-induced thyrotoxicosis before thyroidectomy.
Muscular Dystrophies
Alterations in the pituitary-thyroid axis and 5'-deiodinase activity in mice with muscular dystrophy.
Myocardial Infarction
Short-term exercise training improves cardiac function associated to a better antioxidant response and lower type 3 iodothyronine deiodinase activity after myocardial infarction.
Myocardial Infarction
Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study.
Neoplasms
A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase.
Neoplasms
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
Neoplasms
Consumptive hypothyroidism due to a gastrointestinal stromal tumor expressing type 3 iodothyronine deiodinase.
Neoplasms
Difficult treatment of consumptive hypothyroidism in a child with massive parotid hemangioma.
Neoplasms
Expression of 5'-deiodinase enzymes in normal pituitaries and in various human pituitary adenomas.
Neoplasms
Increased type 3 iodothyronine deiodinase activity in a regrown hepatic hemangioma with consumptive hypothyroidism.
Neoplasms
Induced illness in interleukin-6 (IL-6) knock-out mice: a causal role of IL-6 in the development of the low 3,5,3'-triiodothyronine syndrome.
Neoplasms
Loss of Selenoprotein Iodothyronine Deiodinase 3 Expression Correlates with Progression of Complete Hydatidiform Mole to Gestational Trophoblastic Neoplasia.
Neoplasms
Mechanism of metabolic abnormality of thyroid hormones in Walker 256 carcinosarcoma-bearing rats.
Neoplasms
Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.
Neoplasms
Studies of molecular mechanisms associated with increased deiodinase 3 expression in a case of consumptive hypothyroidism.
Neoplasms
Thyroid hormone deiodinases--a selenoenzyme family acting as gate keepers to thyroid hormone action.
Neoplasms
Tumor necrosis factor-alpha and interferon-gamma modulate gene expression of type I 5'-deiodinase, thyroid peroxidase, and thyroglobulin in FRTL-5 rat thyroid cells.
Neoplasms
Tumor necrosis factor-alpha decreases thyrotropin-induced 5'-deiodinase activity in FRTL-5 thyroid cells.
Neuroblastoma
Cyclic adenosine 3',5'-monophosphate and glucose stimulate thyroxine 5'-deiodinase type II in cultured mouse neuroblastoma cells.
Neuroblastoma
Effect of Taurine on Alterations in Deiodinase 3 Expression Induced by BDE 209 in Human Neuroblasoma-Derived SK-N-AS Cells.
Neuroblastoma
Methylmercury inhibits type II 5'-deiodinase activity in NB41A3 neuroblastoma cells.
Neuroblastoma
Reverse T3 and modulators of the calcium messenger system rapidly decrease T4-5'-deiodinase II activity in cultured mouse neuroblastoma cells.
Non-alcoholic Fatty Liver Disease
A Series of microRNA in the Chromosome 14q32.2 Maternally Imprinted Region Related to Progression of Non-Alcoholic Fatty Liver Disease in a Mouse Model.
Osteosarcoma
Thyroid hormone 5'-deiodinase activity, nuclear binding, and effects on mitogenesis in UMR-106 osteoblastic osteosarcoma cells.
Paraneoplastic Syndromes
A Case of Consumptive Hypothyroidism in a 1-Month-Old Boy with Diffuse Infantile Hepatic Hemangiomas.
Pituitary ACTH Hypersecretion
Expression of 5'-deiodinase enzymes in normal pituitaries and in various human pituitary adenomas.
Pituitary Neoplasms
Expression of 5'-deiodinase enzymes in normal pituitaries and in various human pituitary adenomas.
Scleroderma, Systemic
Euthyroid sick syndrome and inhibitory effect of sera on the activity of thyroid 5'-deiodinase in systemic sclerosis.
Sleep Deprivation
Effect of total sleep deprivation on 5'-deiodinase activity of rat brown adipose tissue.
Starvation
Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine.
Starvation
Selective macrophage depletion in the liver does not prevent the development of the sick euthyroid syndrome in the mouse.
Thyroid Neoplasms
Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.
Thyroid Neoplasms
Thyroid carcinoma: interrelationships between local thyroid hormone metabolism by the type I 5'-deiodinase and the expression of thyroid hormone receptors and other thyroid-specific (de-)differentiation markers.
thyroxine 5-deiodinase deficiency
Euthyroid hyperthyroxinemia due to a generalized 5'-deiodinase defect.
thyroxine 5-deiodinase deficiency
Iodothyronine-5'-deiodinase activity in progenies of hypothyroid rats.
Undifferentiated Connective Tissue Diseases
Euthyroid sick syndrome and inhibitory effect of sera on the activity of thyroid 5'-deiodinase in systemic sclerosis.
html completed
